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An Innovative Tool to Measure Human Skin Strain Distribution in Vivo using Motion Capture and Delaunay Mesh

Published online by Cambridge University Press:  08 May 2012

J. Mahmud*
Affiliation:
Faculty of Mechanical Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia
S. L. Evans
Affiliation:
Institute of Medical Engineering and Medical Physics, School of Engineering, Cardiff University, The Parade, CF24 3AA, United Kingdom
C. A. Holt
Affiliation:
Institute of Medical Engineering and Medical Physics, School of Engineering, Cardiff University, The Parade, CF24 3AA, United Kingdom
*
*Corresponding author (jm@salam.uitm.edu.my)
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Abstract

Skin has a complex structure and its deformation mechanics is still not well defined. In the study of skin biomechanics, the stretch ratio, λ, is an important property, which is determined using strain data. This paper attempts to develop a novel tool by integrating experimental-numerical approach to measure full-field strain distribution of human skin in vivo. Skin deformation in vivo was measured using motion capture system, (which is not a full-field measuring tool) and then by constructing finite elements, its full-field strain contour is produced. The experimental procedure starts by attaching a set of reflective markers onto the skin at the forearm of healthy volunteers. Skin deformation is induced by pulling a nylon filament attached with a loading tab. Three infrared cameras are used to capture the movement of markers during load application. QTM (Qualisys, Sweden) software is used to track markers trajectories and generate data consisting of 3-dimensional markers coordinate. The initial capture is set as the reference marker positions (undeformed skin) and the subsequent images represent the deformed skin relative to the initial. Representing markers as nodes, finite elements are constructed by adjoining three adjacent markers using Delaunay mesh. Strains were deduced from the strain displacement matrix and measured for three subjects at three loading directions. The results are in fair agreement with those obtained by others. The method and output provide a useful addition to understanding skin deformation.

Type
Articles
Copyright
Copyright © The Society of Theoretical and Applied Mechanics, R.O.C. 2012

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References

REFERENCES

1. Delalleau, A., Josse, G., Lagarde, J. M., Zahouani, H. and Bergheau, J. M., “A Nonlinear Elastic Behavior to Identify the Mechanical Properties of Human Skin In vivo,” Skin Research and Technology, 14, pp. 152164 (2008).CrossRefGoogle ScholarPubMed
2. Dobrev, H., “Application of Cutometer Area Parameters for the Study of Human Skin Fatigue,” Skin Research and Technology, 11, pp. 120122 (2005).CrossRefGoogle Scholar
3. Bader, D. L. and Bowker, P., “Mechanical Characteristics of Skin and Underlying Tissues In vivo,” Biomaterials, 4, pp. 305308 (1983).CrossRefGoogle ScholarPubMed
4. Tham, L. M., Lee, H. P. and Lu, C., “Cupping: From a Biomechanical Perspective,” Journal of Biomechanics, 39, pp. 21832193 (2006).CrossRefGoogle ScholarPubMed
5. Evans, S. L., “On the Implementation of a Wrinkling Hyperelastic Membrane Model for Skin and Other Materials,” Computer Methods on Biomechanics and Biomedical Engineering, 12, pp. 319332 (2009).CrossRefGoogle ScholarPubMed
6. Ridge, M. D. and Wright, V., “Mechanical Properties of Skin: A Bioengineering Study of Skin Structure,” Journal of Applied Physiology, 21, pp. 16021606 (1966).CrossRefGoogle ScholarPubMed
7. Mahmud, J., Holt, C. A. and Evans, S. L., “An Innovative Application of a Small Scale Motion Analysis Technique to Quantify Human Skin Deformation In vivo,” Journal of Biomechanics, 43, pp. 10021006 (2010).CrossRefGoogle ScholarPubMed
8. Khatyr, F., Imberdis, C., Varchon, D., Lagarde, J. M. and Josse, G., “Measurement of the Mechanical Properties of the Skin Using the Suction Test,” Skin Research and Technology, 12, pp. 2431 (2006).CrossRefGoogle ScholarPubMed
9. Pierard-Franchimont, C., Henry, F. and Pierard, G. E., “Mechanical Properties of Primary Anetoderma in a Child,” Skin Research and Technology, 3, pp. 8183 (1997).CrossRefGoogle ScholarPubMed
10. Diridollou, S., Berson, M., Vabre, V., Black, D., Karlsson, B., Auriol, F., Gregoire, J. M., Yvon, C., Vaillant, L., Gall, Y. and Patat, F., “An In vivo Method for Measuring the Mechanical Properties of the Skin Using Ultrasound,” Ultrasound in Medicine & Biology, 24, pp. 215224 (1998).CrossRefGoogle Scholar
11. Jemec, G. B. E., Selvaag, E, Agren, M. and Wulf, H. C., “Measurement of the Mechanical Properties of Skin with Ballistometer and Suction Cup,” Skin Research and Technology, 7, pp. 122126 (2001).CrossRefGoogle ScholarPubMed
12. Smalls, L. K., Wickett, R. R. and Visscher, M. O., “Effect of Dermal Thickness, Tissue Composition and Body Site on Skin Biomechanical Properties,” Skin Research and Technology, 12, pp. 4349 (2006).CrossRefGoogle ScholarPubMed
13. Wan Abas, W. A. B. and Barbenel, J. C., “Uniaxial Tension Test of Human Skin In vivo,” Journal of Biomedical Engineering, 4, pp. 6571 (1982).CrossRefGoogle ScholarPubMed
14. Lim, K. H., Chew, C. M., Chen, P. Y. C., Jeyapalina, S., Ho, H. N., Rappel, J. K. and Lim, B. H., “New Extensometer to Measure In vivo Uniaxial Mechanical Properties of Human Skin,” Journal of Biomechanics, 41, pp. 931936 (2008).CrossRefGoogle ScholarPubMed
15. Chapuis, J. F. and Agache, P., “A New Technique to Study the Mechanical Properties of Collagen Lattices,” Journal of Biomechanics, 25, pp. 115120 (1992).CrossRefGoogle Scholar
16. Lafrance, H., Yahia, L. H., Germain, L. and Auger, F. A., “Mechanical Properties of Human Skin Equivalents Submitted to Cyclic Tensile Forces,” Skin Research and Technology, 4, pp. 228236 (1998).CrossRefGoogle ScholarPubMed
17. Highley, D. R., Coomey, M., Denbeste, M. and Wolfram, L. J., “Frictional Properties of Skin,” Journal of Investigative Dermatology, 69, pp. 303305 (1977).CrossRefGoogle ScholarPubMed
18. Agache, P. G., Monneur, C., Leveque, J. L. and de Rigal, J., “Mechanical Properties and Young's Modulus of Human Skin In vivo,” Archives of Dermatological Research, 269, pp. 221232 (1980).CrossRefGoogle ScholarPubMed
19. Leveque, J. L., de Rigal, J., Agache, P. G. and Monneur, C., “Influence of Ageing on the In Vivo Extensibility of Human Skin at a Low Stress,” Archives of Dermatological Research, 269, pp. 127135 (1980).CrossRefGoogle Scholar
20. Sanders, J. E., Garbini, J. L., Leschen, J. M., Allen, M. S. and Jorgensen, J. E., “A Bidirectional Load Applicator for the Investigation of Skin Response to Mechanical Stress,” IEEE Transactions on Biomedical Engineering, 44, pp. 290296 (1997).CrossRefGoogle ScholarPubMed
21. Payne, P. A., “Measurement of Properties and Function of Skin,” Clinical Physics & Physiological Measurement, 12, pp. 105129 (1991).CrossRefGoogle ScholarPubMed
22. Jachowicz, J., McMullen, R. and Preetypaul, D., “Indentometric Analysis of In vivo Skin and Comparison with Artificial Skin Models,” Skin Research and Technology, 13, pp. 299309 (2007).CrossRefGoogle ScholarPubMed
23. Tran, H. V., Charleux, F., Rachik, M., Ehrlacher, A. and Ho Ba Tho, M. C., “In vivo Characterization of the Mechanical Properties of Human Skin Derived from MRI and Indentation Techniques,” Computer Methods in Biomechanics and Biomedical Engineering, 10, pp. 401407 (2007).CrossRefGoogle ScholarPubMed
24. Shergold, O. A. and Fleck, N. A., “Mechanisms of Deep Penetration of Soft Solids, with the Application to the Injection and Wounding of Skin,” Proceedings of the Royal Society London A, 460, pp. 30373058 (2004).CrossRefGoogle Scholar
25. Fung, Y. C., Biomechanics: Mechanical Properties of Living Tissue, 2nd Ed., Springer-Verlag New York Inc., U.S.A., pp. 13 (1993).CrossRefGoogle Scholar
26. Screen, H. R. C. and Evans, S. L., “Measuring Strain Distribution in the Tendon Using Confocal Microscopy and Finite Elements,” Journal of Strain Analysis for Engineering Design, 44, pp. 327335 (2009).CrossRefGoogle Scholar
27. Guan, E., Smilow, S., Rafailovich, M. and Sokolov, J., “Determining the Mechanical Properties of Rat Skin with Digital Image Speckle Correlation,” Dermatology, 208, pp. 112119 (2004).CrossRefGoogle ScholarPubMed
28. Sutton, M. A., Ke, X., Lessner, S. M., Goldbach, M., Yost, M., Zhao, F. and Schreier, H. W., “Strain Field Measurements on Mouse Carotid Arteries Using Microscopic Three-Dimensional Digital Image Correlation,” Journal of Biomedical Materials Research Part A, pp. 178190 (2008).CrossRefGoogle ScholarPubMed
29. Staloff, I. A. and Rafailovitch, M., “Measuement of Skin Stretch using Digital Imanage Speckle Correlation,” Skin Research and Technology, 14, pp. 298303 (2008).CrossRefGoogle Scholar
30. Evans, S. L. and Holt, C. A., “Measuring the Mechanical Properties of Human Skin In Vivo using Digital Image Correlation and Finite Element Modelling,” Journal of Strain Analysis for Engineering Design, 44, pp. 337345 (2009).CrossRefGoogle Scholar
31. Wang, T.-M., Chen, H.-L., Hsu, W.-C., Liu, M.-W. and Lu, T.-W., “Biomechanical Role of the Loco-motor System in Controlling Body Center of Mass Motion in Older Adults During Obstructed Gait,” Journal of Mechanics, 26, pp. 195203 (2010).CrossRefGoogle Scholar
32. Hsu, W.-C., Wang, T.-M., Liu, M.-W., Chen, H.-L. and Lu, T.-W., “Control of Body's Center of Mass Motion During Level Walking and Obstacle-Crossing in Older Patients with Knee Osteoarthritis,” Journal of Mechanics, 26, pp. 229237 (2010).CrossRefGoogle Scholar
33. Liu, H., Holt, C. A. and Evans, S. L., “Accuracy and Repeatability of an Optical Motion Analysis System for Measuring Small Deformations of Biological Tissues,” Journal of Biomechanics, 40, pp. 210214 (2007).CrossRefGoogle ScholarPubMed
34. Cappozzo, A., Catani, F., Della Croce, U. and Leardini, A., “Position and Orientation in Space of Bones during Movement: Anatomical Frame Definition and Determination,” Clinical Biomechanics, 10, pp. 171178 (1995).CrossRefGoogle ScholarPubMed
35. Whatling, G. M., Dabke, H. V., Holt, C. A., Jones, L., Madete, J., Alderman, P. M. and Roberts, P., “Objective Functional Assessment of Total Hip Arthroplasty Following Two Common Surgical Approaches: The Posterior and Direct Lateral Approaches,” Proceedings of the IMechE [H], 222, pp. 897905 (2008).CrossRefGoogle ScholarPubMed
36. Liu, H., “Development of a Novel System to Measure and Calculate Tooth Movements for Studying the Properties of the Periodontal Ligament,” Ph.D. thesis, School of Engineering, Cardiff University Press, UK (2006).Google Scholar
37. Matlab vR2008b Manual (Delaunay function, Matlab, The MathWorks, Inc.)Google Scholar
39. Dyer, R., Zhang, H. and Moller, T., “Delaunay Mesh Construction,” Proceedings of the 5th Eurographics Symposium on Geometry Processing, Spain, pp. 273282 (2007).Google Scholar
40. Rees, D., Basic Engineering Plasticity — An Introduction with Engineering and Manufacturing Applications, Butterworth-Heinemann U.S.A., p. 41 (2006).Google Scholar