Book contents
- 50 Big Debates in Gynecologic Oncology
- 50 Big Debates in Gynecologic Oncology
- Copyright page
- Contents
- Contributors
- Section I Perioperative Management
- Section II Screening, Prevention, and Early Diagnosis
- Section III Ovarian Cancer
- Section IV Endometrial Cancer
- Section V Cervical Cancer
- Section VI Vaginal and Vulvar Cancer
- Debate 48A Should the Subsequent Management of Patients with Vulvar Cancer and a Positive Sentinel Lymph Node be Complete Groin Lymph Node Dissection or Radiation Therapy?
- Debate 48B Should the Subsequent Management of Patients with Vulvar Cancer and a Positive Sentinel Lymph Node be Complete Groin Lymph Node Dissection or Radiation Therapy?
- Debate 49A What is the Best Treatment for Stage I Vulvar Squamous Cell Carcinoma with either a Close or Positive Surgical Margin?
- Debate 49B What is the Best Treatment for Stage I Vulvar Squamous Cell Carcinoma with either a Close or Positive Surgical Margin?
- Debate 50A Should Adjuvant Radiation be Given to Women with Single Node Positive Vulvar Cancer?
- Debate 50B Should Adjuvant Radiation Therapy be Given to Patients with Single Node Positive Vulvar Cancer?
- Debate 51A Is Pelvic Exenteration an Option for a Pelvic Recurrence of a Vulvar/Vaginal Melanoma after Previous Radiation Therapy?
- Debate 51B Is Pelvic Exenteration an Option for a Pelvic Recurrence of a Vulvar/Vaginal Melanoma after Previous Radiation Therapy?
- Index
- References
Debate 50B - Should Adjuvant Radiation Therapy be Given to Patients with Single Node Positive Vulvar Cancer?
No
from Section VI - Vaginal and Vulvar Cancer
Published online by Cambridge University Press: 20 July 2023
- 50 Big Debates in Gynecologic Oncology
- 50 Big Debates in Gynecologic Oncology
- Copyright page
- Contents
- Contributors
- Section I Perioperative Management
- Section II Screening, Prevention, and Early Diagnosis
- Section III Ovarian Cancer
- Section IV Endometrial Cancer
- Section V Cervical Cancer
- Section VI Vaginal and Vulvar Cancer
- Debate 48A Should the Subsequent Management of Patients with Vulvar Cancer and a Positive Sentinel Lymph Node be Complete Groin Lymph Node Dissection or Radiation Therapy?
- Debate 48B Should the Subsequent Management of Patients with Vulvar Cancer and a Positive Sentinel Lymph Node be Complete Groin Lymph Node Dissection or Radiation Therapy?
- Debate 49A What is the Best Treatment for Stage I Vulvar Squamous Cell Carcinoma with either a Close or Positive Surgical Margin?
- Debate 49B What is the Best Treatment for Stage I Vulvar Squamous Cell Carcinoma with either a Close or Positive Surgical Margin?
- Debate 50A Should Adjuvant Radiation be Given to Women with Single Node Positive Vulvar Cancer?
- Debate 50B Should Adjuvant Radiation Therapy be Given to Patients with Single Node Positive Vulvar Cancer?
- Debate 51A Is Pelvic Exenteration an Option for a Pelvic Recurrence of a Vulvar/Vaginal Melanoma after Previous Radiation Therapy?
- Debate 51B Is Pelvic Exenteration an Option for a Pelvic Recurrence of a Vulvar/Vaginal Melanoma after Previous Radiation Therapy?
- Index
- References
Summary
Inguino-femoral lymph node metastasis in vulvar cancer accounts for increased risk of recurrence and 50% decrease in survival. Adjuvant radiotherapy for single positive IFLN vulvar cancer has persisted as a controversial topic since the publication of GOG 37. Retrospective data from Germany indicates that there is no difference in survival for patients with single node positive vulvar cancer treated with adjuvant radiotherapy or observation. Radical surgery, even with SLNB, followed by radiotherapy can lead to devastating and difficult-to-treat complications including wound infections, lymphedema, pain, and bone fractures. Considering these complications, overall quality of life, and the limited data demonstrating improved survival benefit, it would be beneficial to withhold adjuvant radiotherapy for patients with single-positive IFLN vulvar cancer. Further studies aimed at understanding the molecular landscape and investigating targeted and immunotherapy for vulvar cancer will aid in the treatment of this complex cancer.
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- 50 Big Debates in Gynecologic Oncology , pp. 304 - 306Publisher: Cambridge University PressPrint publication year: 2023