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  • Print publication year: 2012
  • Online publication date: November 2012

4 - Severe preeclampsiaand eclampsia

from Section 2 - Algorithms for Management of the Top Five ‘Direct Killers’


1. National Institute for Health and Clinical Excellence. Hypertension in Pregnancy: The Management of Hypertensive Disorders during Pregnancy. CG107. London: National Institute for Health and Clinical Excellence, 2010.
2. JimB, SharmaS, KebedeT, AcharyaA. Hypertension in pregnancy: a comprehensive update. Cardiol Rev 2010; 18 (4): 178–189.
3. GiguereY, CharlandM, BujoldEet al. Combining biochemical and ultrasonographic markers in predicting pre-eclampsia: a systematic review. Clin Chem 2010; 56 (3): 361–375.
4. ThangaratinamS, IsmailKM, SharpSet al. Accuracy of serum uric acid in predicting complications of pre-eclampsia: a systematic review. Br J Obstet Gynaecol 2006; 113: 369–378.
5. CnossenJ S, VollebregtKC, de VriezeNet al. Accuracy of mean arterial pressure and blood pressure measurements in predicting pre-eclampsia: systematic review and meta-analysis. BMJ 2008; 336: 1117.
6. CnossenJS, LeeflangMM, de HaanEEet al. Accuracy of body mass index in predicting pre-eclampsia: bivariate meta-analysis. Br J Obstet Gynaecol 2007; 114 (12): 1477–1485.
7. PolliottiBM, FryA, GordonMDet al. Second-trimester maternal serum placental growth factor and vascular endothelial growth factor for predicting severe, early-onset pre-eclampsia. Obstet Gynecol 2003; 101 (6): 1266–1274.
8. CnossenJS, MorrisRK, ter RietGet al. Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: a systematic review and bivariable meta-analysis. Can Med Assoc J 2008; 178 (6): 701–711.
9. ThangaratinamS, CoomarasamyA, O’MahoneyFet al. Estimation of proteinuria as a predictor of complications of pre-eclampsia: a systematic review. BMC Med 2009; 24 (7): 10.
10. DuleyL, Henderson-SmartDJ, MeherS, KingJF. Antiplatelet agents for preventing pre-eclampsia and its complications. Cochrane Database Syst Rev 2007; 2: CD004659.
11. HofmeyrGJ, LawrieTA, AtallahÁN, DuleyL. Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems. Cochrane Database Syst Rev 2010; 8: CD001059.
12. MageeLA, Von DadelsczenP, ChanSet al. The Control of Hypertension in Pregnancy Study pilot data. Br J Obstet Gynaecol 2007: 114 (6): 770, e13–20.
13. DuleyL, GülmezogluAM, Henderson-SmartDJ, ChouD. Magnesium sulphate and other anticonvulsants for women with pre-eclampsia. Cochrane Database Syst Rev 2010; 11: CD000025.
14. PapannaR, MannLK, KouidesRWet al. Protein/creatinine ratio in pre-eclampsia: a systematic review. Obstetrics and Gynaecology 2008; 112 (1): 135–144.
15.Which anticonvulsant for women with eclampsia? Evidence from the Collaborative Eclampsia Trial. Lancet 1995; 345 (8963): 1455–1463; erratum in Lancet 1995; 346: 258.
16. KoopmansC, BijlengaD, GrownHet al. Induction of labour versus expectant monitoring for gestational hypertension or mild pre-eclampsia after 36 weeks’ gestation (HYPITAT): a multicentre open-label randomised controlled trial. Lancet 2009; 374 (9694): 979–988.
17.HYPITAT-II Trial. Study Information. [Accessed 17/03/2011].
18. Resuscitation Council (UK). Resuscitation Guidelines: Adult Advanced Life Support. 2010. [Accessed 28/02/2011].
19. TuffnellDJ, ShennanAH, WaughJJS, WalkerJJ. The Management of Severe Pre-Eclampsia/Eclampsia. Guideline No. 10(A). London: RCOG, 2006.
20. World Health Organization, UNIFPA, UNICEF, The World Bank. Pregnancy, Childbirth, Postpartum and Newborn Care: A Guide for Essential Practice. Geneva: WHO, 2006.