Book contents
- Pediatric Pathology of Hematopoietic and Histiocytic Disorders
- Pediatric Pathology of Hematopoietic and Histiocytic Disorders
- Copyright page
- Epigraph
- Contents
- Contributors
- Section I General Hematology and Hematopathology
- Section II Non-Neoplastic Hematologic Disorders of Blood and Bone Marrow
- Section III Non-Neoplastic Disorders of Extramedullary Lymphoid Tissues
- Section IV Neoplastic Disorders of Bone Marrow
- Section V Mature Lymphoid Neoplasms
- Chapter 20 Mature B-Cell Non-Hodgkin Neoplasms
- Chapter 21 Mature T-Cell and NK-Cell Non-Hodgkin Lymphomas
- Chapter 22 Hodgkin Lymphoma
- Chapter 23 Immunodeficiency-Associated Lymphoproliferative Disorders
- Section VI Histiocytic Disorders and Neoplasms
- Index
- References
Chapter 23 - Immunodeficiency-Associated Lymphoproliferative Disorders
from Section V - Mature Lymphoid Neoplasms
Published online by Cambridge University Press: 25 January 2024
Book contents
- Pediatric Pathology of Hematopoietic and Histiocytic Disorders
- Pediatric Pathology of Hematopoietic and Histiocytic Disorders
- Copyright page
- Epigraph
- Contents
- Contributors
- Section I General Hematology and Hematopathology
- Section II Non-Neoplastic Hematologic Disorders of Blood and Bone Marrow
- Section III Non-Neoplastic Disorders of Extramedullary Lymphoid Tissues
- Section IV Neoplastic Disorders of Bone Marrow
- Section V Mature Lymphoid Neoplasms
- Chapter 20 Mature B-Cell Non-Hodgkin Neoplasms
- Chapter 21 Mature T-Cell and NK-Cell Non-Hodgkin Lymphomas
- Chapter 22 Hodgkin Lymphoma
- Chapter 23 Immunodeficiency-Associated Lymphoproliferative Disorders
- Section VI Histiocytic Disorders and Neoplasms
- Index
- References
Summary
Immunodeficiency is a state of reduced ability to produce an adequate immune response due to an insufficiency or absence of antibodies, immune cells, or both. Immunodeficiency disorders can be primary (inherited/congenital) or acquired. Acquired immunodeficiencies can result from HIV infection, solid organ or hematopoietic stem cell transplantation, and other iatrogenic conditions, such as chemotherapy.
Immunodeficiency is associated with an increased risk of benign and malignant lymphoproliferative disorders (LPDs) [1]. As a result, a wide range of clinical manifestations and diseases can develop. Pathologists may face a challenge in making an accurate diagnosis and classification of lesion tissues from these patients because of the different nature of their immune systems in this context. Therefore, it is important that the pathologist be informed of the underlying condition when evaluating specimens from these patients [1].
- Type
- Chapter
- Information
- Pediatric Pathology of Hematopoietic and Histiocytic Disorders , pp. 296 - 306Publisher: Cambridge University PressPrint publication year: 2024
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