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Boots on the ground in Africa's ancient DNA ‘revolution’: archaeological perspectives on ethics and best practices

  • Mary E. Prendergast (a1) and Elizabeth Sawchuk (a2)
Abstract

Recent methodological advances have increased the pace and scale of African ancient DNA (aDNA) research, inciting a rush to sample broadly from museum collections, and raising ethical concerns over the destruction of human remains. In the absence of discipline-wide protocols, teams are often left to navigate aDNA sampling on an individual basis, contributing to widely varying practices that do not always protect the long-term integrity of collections. As those on the frontline, archaeologists and curators must create and adhere to best practices. We review ethical issues particular to African aDNA contexts and suggest protocols with the aim of initiating public discussion.

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This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction in any medium, provided the original work is properly cited.
Corresponding author
*Authors for correspondence (Email: mprendergast@post.harvard.edu; esawchuk@gmail.com)
References
Hide All
Allentoft, M.E. 2013. Recovering samples for ancient DNA research—guidelines for the field archaeologist. Antiquity Project Gallery 87 (338). Available at: https://www.antiquity.ac.uk/projgall/allentoft338/ (accessed 17 May 2018).
Antoine, D. & Ambers, J.. 2015. The scientific analysis of human remains from the British Museum Collection: research potential and examples from the Nile Valley, in Fletcher, A., Antoine, D. & Hill, J.D. (ed.) Regarding the dead: 2030. London: British Museum.
APABE (Advisory Panel on the Archaeology of Burials in England). 2013. Science and the dead: a guideline for the destructive sampling of archaeological human remains for scientific analysis. Swindon: English Heritage.
Buikstra, J.E. & Ubelaker, D.H. (ed.). 1994. Standards for data collection from human skeletal remains (Arkansas Archeological Survey Research Series 44). Fayetteville: Arkansas Archeological Survey Research Series.
CBD (Convention on Biological Diversity). 2011. Nagoya protocol on access to genetic resources and the fair and equitable sharing of benefits arising from their utilization to the Convention on Biological Diversity. Quebec: Secretariat of the Convention on Biological Diversity. Available at: https://www.cbd.int/abs/doc/protocol/nagoya-protocol-en.pdf (accessed 17 May 2018).
Dabney, J., Knapp, M., Glocke, I., Gansauge, M.-T., Weihmann, A., Nickel, B., Valdiosera, C., Garcia, N., Pääbo, S., Arsuaga, J.-L. & Meyer, M.. 2013. Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragment. Proceedings of the National Academy of Sciences of the USA 110: 15758–63. https://doi.org/10.1073/pnas.1314445110
De Luna, K.M., Fleisher, J.B. & McIntosh, S.K.. 2012. Thinking across the African past: interdisciplinarity and early history. African Archaeological Review 29: 7594. https://doi.org/10.1007/s10437-012-9123-y
Eller, J.D. 1999. From culture to ethnicity to conflict: an anthropological perspective on international ethnic conflict. Ann Arbor: University of Michigan Press. https://doi.org/10.3998/mpub.14446
Fu, Q., Meyer, M., Gao, X., Stenzel, U., Burbano, H.A., Kelso, J. & Pääbo, S.. 2013. DNA analysis of an early modern human from Tianyuan Cave, China. Proceedings of the National Academy of Sciences of the USA 110: 2223–27. https://doi.org/10.1073/pnas.1221359110
Fu, Q., Hajdinjak, M., Moldovan, O.T., Constantin, S., Mallick, S., Skoglund, P., Patterson, N., Rohland, N., Lazaridis, I., Nickel, B., Viola, B., Prufer, K., Meyer, M., Kelso, J., Reich, D. & Paabo, S.. 2015. An early modern human from Romania with a recent Neanderthal ancestor. Nature 524: 216–19. https://doi.org/10.1038/nature14558
Gallego Llorente, M., Jones, E.R., Eriksson, A., Siska, V., Arthur, K.W., Arthur, J.W., Curtis, M.C., Stock, J.T., Coltorti, M., Pieruccini, P., Stretton, S., Brock, F., Higham, T., Park, Y., Hofreiter, M., Bradley, D.G., Bhak, J., Pinhasi, R. & Manica, A.. 2015. Ancient Ethiopian genome reveals extensive Eurasian admixture in Eastern Africa. Science 350: 820–22. https://doi.org/10.1126/science.aad2879
Giblin, J., King, R. & Smith, B.. 2014. Introduction: de-centring ethical assumptions by re-centring ethical debate in African archaeology. Azania: Archaeological Research in Africa 49: 131–35. https://doi.org/10.1080/0067270X.2014.904979
Hrdlicka, A. 1918. Physical anthropology: its scope and aims; its history and present status in America. American Journal of Physical Anthropology 1: 133–82.
Joseph, T. 2017. How genetics is settling the Aryan migration debate. The Hindu, 16 June 2017.
Kaestle, F.A. & Horsburgh, K.A.. 2002. Ancient DNA in anthropology: methods, applications, and ethics. American Journal of Physical Anthropology Supplement 5: 92130. https://doi.org/10.1002/ajpa.10179
MacEachern, S. 2000. Genes, tribes, and African history. Current Anthropology 41: 357–84. https://doi.org/10.1086/300144
MacEachern, S. 2013. Genetics and archaeology, in Mitchell, P. & Lane, P.J. (ed.) The Oxford handbook of African archaeology: 6576. Oxford: Oxford University Press.
Makarewicz, C., Marom, N. & Bar-Oz, G.. 2017. Palaeobiology: ensure equal access to ancient DNA. Nature 548: 158. https://doi.org/10.1038/548158a
Matisoo-Smith, E. & Horsburgh, K.A.. 2012. DNA for archaeologists. Walnut Creek (CA): Left Coast.
Meyer, M. & Kircher, M.. 2010. Illumina sequencing library preparation for highly multiplexed target capture and sequencing. Cold Spring Harbor Protocols 2010 (6): 110. https://doi.org/10.1101/pdb.prot5448
Meyer, M., Kircher, M., Gansauge, M.T., Li, H., Racimo, F., Mallick, S., Schraiber, J.G., Jay, F., Prufer, K., de Filippo, C., Sudmant, P.H., Alkan, C., Fu, Q., Do, R., Rohland, N., Tandon, A., Siebauer, M., Green, R.E., Bryc, K., Briggs, A.W., Stenzel, U., Dabney, J., Shendure, J., Kitzman, J., Hammer, M.F., Shunkov, M.V., Derevianko, A.P., Patterson, N., Andres, A.M., Eichler, E.E., Slatkin, M., Reich, D., Kelso, J. & Paabo, S.. 2012. A high-coverage genome sequence from an archaic Denisovan individual. Science 338: 222–26. https://doi.org/10.1126/science.1224344
Mitchell, P.D. & Brickley, M. (ed.). 2017. Updated guidelines to the standards for recording human remains. Reading: Chartered Institute for Archaeologists.
Morris, A.G. 2014. Controversies about the study of human remains in post-Apartheid South Africa, in O'Donnabhain, B. & Lozada, M.C. (ed.) Archaeological human remains: global perspectives: 189–98. Cham: Springer.
Morris, A.G. 2017. Ancient DNA comes of age, but still has some teenage problems. South African Journal of Science 113 (9–10): 12. https://doi.org/10.17159/sajs.2017/a0232
Morris, A.G., Heinze, A., Chan, E.K.F., Smith, A.B. & Hayes, V.M.. 2014. First ancient mitochondrial human genome from a prepastoralist southern African. Genome Biology and Evolution 6: 2647–53. https://doi.org/10.1093/gbe/evu202
Musonda, F.B. 2013. Decolonising the Broken Hill skull: cultural loss and a pathway to Zambian archaeological sovereignty. African Archaeological Review 30: 195220. https://doi.org/10.1007/s10437-013-9134-3
Nienaber, W.C. & Steyn, M.. 2011. Republic of South Africa, in Márquez-Grant, N. & Fibiger, L. (ed.) Physical anthropology and legislation: European perspectives and beyond: 501–12. New York: Routledge.
Nordling, L. 2017. How the genomics revolution could finally help Africa. Nature 544: 2022. https://doi.org/10.1038/544020a
Parsons, N. & Segobye, A.. 2002. Missing persons and stolen bodies: the repatriation of ‘El Negro’ to Botswana, in Fforde, C., Hubert, J. & Turnbull, P. (ed.) The dead and their possessions: repatriation in principle, policy and practice: 245–55. London: Routledge. https://doi.org/10.4324/9780203165775_ chapter_20
Pinhasi, R., Fernandes, D., Sirak, K., Novak, M., Connell, S., Alpaslan-Roodenberg, S., Gerritsen, F., Moiseyev, V., Gromov, A., Raczky, P., Anders, A., Pietrusewsky, M., Rollefson, G., Jovanovic, M., Trinhhoang, H., Bar-Oz, G., Oxenham, M., Matsumura, H. & Hofreiter, M.. 2015. Optimal ancient DNA yields from the inner ear part of the human petrous bone. PLoS ONE 10: e0129102. https://doi.org/10.1371/journal.pone.0129102
Pluciennik, M. 2006. Clash of cultures? Archaeology and genetics. Documenta Praehistorica 33: 3949. https://doi.org/10.4312/dp.33.6
Pollard, AM. & Bray, P.. 2007. A bicycle made for two? The integration of scientific techniques into archaeological interpretation. Annual Review of Anthropology 36: 245–59.
Robertshaw, P. 2012. African archaeology, multidisciplinary reconstructions of Africa's recent past, and archaeology's role in future collaborative research. African Archaeological Review 29: 95108. https://doi.org/10.1007/s10437-012-9113-0
Rodríguez-Varela, R., Günther, T., Krzewińska, M., Storå, J., Gillingwater, T.H., MacCallum, M., Arsuaga, J.L., Dobney, K., Valdiosera, C., Jakobsson, M., Götherström, A. & Girdland-Flink, L.. 2017. Genomic analyses of pre-European conquest human remains from the Canary Islands reveal close affinity to modern North Africans. Current Biology 27: 33963402. https://doi.org/10.1016/j.cub.2017.09.059
Sanders, E.R. 1969. The Hamitic hypothesis: its origin and functions in time perspective. Journal of African History 10: 521–32. https://doi.org/10.1017/S0021853700009683
SASI. 2017. San code of research ethics. Kimberly: South African San Institute. Available at: http://trust-project.eu/wp-content/uploads/2017/03/San-Code-of-RESEARCH-Ethics-Booklet-final.pdf (accessed 17 May 2018).
Schlebusch, C.M., Malmström, H., Günther, T., Sjödin, P., Coutinho, A., Edlund, H., Munters, A.R., Vicente, M., Steyn, M., Soodyall, H., Lombard, M. & Jakobsson, M.. 2017. Southern African ancient genomes estimate modern human divergence to 350,000 to 260,000 years ago. Science 358: 652–55. https://doi.org/10.1126/science.aao6266
Schmidt, P.R. & Pikirayi, I.. (ed.). 2016. Community archaeology and heritage in Africa: decolonizing practice. London: Routledge.
Schuenemann, V.J., Peltzer, A., Welte, B., van Pelt, W.P., Molak, M., Wang, C.C., Furtwangler, A., Urban, C., Reiter, E., Nieselt, K., Tessmann, B., Francken, M., Harvati, K., Haak, W., Schiffels, S. & Krause, J.. 2017. Ancient Egyptian mummy genomes suggest an increase of Sub-Saharan African ancestry in post-Roman periods. Nature Communications 8: 15694. https://doi.org/10.1038/ncomms15694
Seligman, C.G. 1930. Races of Africa. London: Thornton Butterworth Ltd.
Sirak, K.A., Fernandes, D.M., Cheronet, O., Novak, M., Gamarra, B., Balassa, T., Bernert, Z., Cseki, A., Dani, J., Gallina, J.Z., Kocsis-Buruzs, G., Kovari, I., Laszlo, O., Pap, I., Patay, R., Petkes, Z., Szenthe, G., Szeniczey, T., Hajdu, T. & Pinhasi, R.. 2017. A minimally invasive method for sampling human petrous bones from the cranial base for ancient DNA analysis. Biotechniques 62: 283–89. https://doi.org/10.2144/000114558
Skoglund, P., Thompson, J.C., Prendergast, M.E., Mittnik, A., Sirak, K., Hajdinjak, M., Salie, T., Rohland, N., Mallick, S., Peltzer, A., Heinze, A., Olalde, I., Ferry, M., Harney, E., Michel, M., Stewardson, K., Cerezo-Román, J.I., Chiumia, C., Crowther, A., Gomani-Chindebvu, E., Gidna, A.O., Grillo, K.M., Helenius, I.T., Hellenthal, G., Helm, R., Horton, M., López, S., Mabulla, A.Z.P., Parkington, J., Shipton, C., Thomas, M.G., Tibesasa, R., Welling, M., Hayes, V.M., Kennett, D.J., Ramesar, R., Meyer, M., Pääbo, S., Patterson, N., Morris, A.G., Boivin, N., Pinhasi, R., Krause, J. & Reich, D.. 2017. Reconstructing prehistoric African population structure. Cell 171: 5971. https://doi.org/10.1016/j.cell.2017.08.049
Steyn, M., Morris, A.G., Mosothwane, M.N., Nienaber, W.C. & Maat, G.J.R.. 2013. Opening the cupboard: lessons in biology and history from African skeletons. Goodwin Series 11: 15.
Straight, B., Lane, P.J., Hilton, C.E. & Letua, M.. 2015. ‘It was maendeleo that removed them’: disturbing burials and reciprocal knowledge production in a context of collaborative archaeology. Journal of the Royal Anthropological Institute 21: 391418. https://doi.org/10.1111/1467-9655.12212
Tilley, H. 2016. Medicine, empires, and ethics in colonial Africa. AMA Journal of Ethics 18: 743–53. https://doi.org/10.1001/journalofethics.2016.18.7.mhst1-1607
Trigger, B.G. 2006. A history of archaeological thought (2nd edition). Cambridge: Cambridge University Press.
WAC (World Archaeological Congress). 1989. The Vermillion Accord on human remains. Available at: http://worldarch.org/code-of-ethics/ (accessed 17 May 2018).
Wittwer-Backofen, U., Kästner, M., Möller, D., Vohberger, M., Lutz-Bonengel, S. & Speck, D.. 2014. Ambiguous provenance? Experience with provenance analysis of human remains from Namibia in the Alexander Ecker Collection. Anthropologischer Anzeiger Journal of Biological and Clinical Anthropology 71 (1–2): 6586.
Wright, G.E., Koornhof, P.G., Adeyemo, A.A. & Tiffin, N.. 2013. Ethical and legal implications of whole genome and whole exome sequencing in African populations. BMC Medical Ethics 14: 21. https://doi.org/10.1186/1472-6939-14-21
Yakubu, A., Tindana, P., Matimba, A., Littler, K., Munung, N.S., Madden, E., Staunton, C. & De Vries, J.. 2018. Model framework for governance of genomic research and biobanking in Africa—a content description. AAS Open Research 1: 13. https://doi.org/10.12688/aasopenres.12844.1
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