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  • Cited by 2
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    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Morrow, Jonathan D. Saunders, Benjamin T. Maren, Stephen and Robinson, Terry E. 2015. Sign-tracking to an appetitive cue predicts incubation of conditioned fear in rats. Behavioural Brain Research, Vol. 276, p. 59.

    Wakefield, Jerome C. 2013. DSM-5 and the General Definition of Personality Disorder. Clinical Social Work Journal, Vol. 41, Issue. 2, p. 168.


High mental disorder rates are based on invalid measures: Questions about the claimed ubiquity of mutation-induced dysfunction

  • Jerome C. Wakefield (a1)
  • DOI:
  • Published online: 09 November 2006

Three reservations about Keller & Miller's (K&M's) argument are explored: Serious validity problems afflict epidemiological criteria discriminating disorders from non-disorders, so high rates may be misleading. Normal variation need not be mild disorder, contrary to a possible interpretation of K&M's article. And, rather than mutation-selection balance, true disorders may result from unselected combinations of normal variants over many loci.

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Behavioral and Brain Sciences
  • ISSN: 0140-525X
  • EISSN: 1469-1825
  • URL: /core/journals/behavioral-and-brain-sciences
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