Skip to main content
×
Home
    • Aa
    • Aa

Neural grafting in human disease versus animal models: Cautionary notes

  • Kathy Steece-Collier (a1)
Abstract
Abstract

Over the past two decades, research on neural transplantation in animal models of neurodegeneration has provided provocative in sights into the therapeutic use of grafted tissue for various neurological diseases. Although great strides have been made and functional benefits gained in these animal models, much information is still needed with regard to transplantation in human patients. Several factors are unique to human disease, for example, age of the recipient, duration of disease, and drug interaction with grafted cells; these need to be explored before grafting can be considered a safe and effective therapeutic tool.

Copyright
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

E. O. Backlund , P. -O. Granberg , B. Hamberger , G. Sedwall , A. Seiger & L. Olson (1985) Transplantation of adrenal medullary tissue to striatum in Parkinsonism. In: Neural grafting in the mammalian CNS, ed. A. Björklund & U. Stenevi . Elsevier . [aDGS]

S. Koch & D. E. Leary (1992) A century of psychology as science. American Psychological Association. [MPL]

E. A. Neuwelt (1989) Implications of the blood-brain barrier and its manipulation. Vol. I: Basic science aspects. Vol. 2: Clinical aspects. Plenum. aEAN

D. G. Stein & B. A. Sabel (1988) Pharmacological, approaches to the treatment of brain and spinal cord injury. Plenum Press. [arDGS]

D. G. Stein & B. A. Sabel (1988) Pharmacological, approaches to the treatment of brain and spinal cord injury. Plenum Press. [arDGS]

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Behavioral and Brain Sciences
  • ISSN: 0140-525X
  • EISSN: 1469-1825
  • URL: /core/journals/behavioral-and-brain-sciences
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 1 *
Loading metrics...

Abstract views

Total abstract views: 32 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 22nd September 2017. This data will be updated every 24 hours.