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Microdeletion syndromes and psychiatry: An update

  • Melvyn W. B. Zhang, Nikki Fong, Ying Hui Quek, Cyrus S. H. Ho, Beng Yeong Ng and Roger C. M. Ho...
Summary

Microdeletion syndrome is an important topic in intellectual disability, associated with various psychiatric symptoms, such as autism, attention deficit, hyperactivity, obsession and compulsion, and psychosis. In this article, we provide a clinical update on the following syndromes and their associated psychiatric disorders: Prader–Willi syndrome, Angelman syndrome, Williams syndrome, Wolf–Hirschhorn syndrome, cri du chat syndrome, DiGeorge syndrome and Rubinstein–Taybi syndrome.

Learning Objectives

• Gain an up-to-date understanding of the microdeletion syndromes commonly seen in daily practice

• Appreciate the association between underlying chromosomal abnormalities and the resultant intellectual disabilities in microdeletion syndromes

• Gain up-to-date knowledge about the treatment options for the various microdeletion syndromes commonly seen in daily practice

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Copyright
Corresponding author
Correspondence Dr Melvyn Zhang, Associate Consultant and Adjunct Research Scientist, MD6, 14 Medical Drive, #14-01, Singapore 117599. Email: melvyn_wb_zhang@imh.com.sg
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Declaration of Interest

None

Footnotes
References
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BJPsych Advances
  • ISSN: 2056-4678
  • EISSN: 2056-4686
  • URL: /core/journals/bjpsych-advances
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Microdeletion syndromes and psychiatry: An update

  • Melvyn W. B. Zhang, Nikki Fong, Ying Hui Quek, Cyrus S. H. Ho, Beng Yeong Ng and Roger C. M. Ho...
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