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Body mass index and blood glucose in psychiatric and general practice populations

  • Sarah McAvoy (a1), Matthew Cordiner (a1), Jackie Kelly (a1), Laura Chiwanda (a1), Christine Jefferies (a1), Kirsteen Miller (a1) and Polash Shajahan (a1) (a2)...
Abstract
Aims and method

Using a retrospective observational approach, we aimed to discern whether there was a difference in metabolic parameters between psychiatric and general practice populations in the same locality. Second, we aimed to establish differences in metabolic parameters of patients taking olanzapine, clozapine or aripiprazole.

Results

Patients with psychiatric illness had a body mass index (BMI) comparable to that of the general practice population (28.7 v. 29.7 kg/m2), but blood glucose was significantly lower in the general practice population (4.8 v. 6.1 mmol/L). Olanzapine was associated with the lowest BMI (26.1 kg/m2) and aripiprazole the highest (32.2 kg/m2), with no difference in blood glucose between antipsychotics.

Clinical implications

Awareness of environmental factors and how they affect individuals is important and medications are not the only cause of metabolic effects. There may be a channelling bias present, meaning practitioners are cognisant of potential metabolic effects prior to prescribing. Overall monitoring of physical health is important regardless of potential cause.

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Copyright
This is an open-access article published by the Royal College of Psychiatrists and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Corresponding author
Correspondence to Polash Shajahan (polash.shajahan@lanarkshire.scot.nhs.uk)
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Declaration of interest

P.S. has received funding for travel, subsistence and meeting costs for the European College of Neuropsychopharmacology in 2013 from Janssen Pharmaceuticals.

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References
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Body mass index and blood glucose in psychiatric and general practice populations

  • Sarah McAvoy (a1), Matthew Cordiner (a1), Jackie Kelly (a1), Laura Chiwanda (a1), Christine Jefferies (a1), Kirsteen Miller (a1) and Polash Shajahan (a1) (a2)...
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