Skip to main content
×
×
Home

A symptom-based approach to treatment of psychosis in autism spectrum disorder

  • Victoria Bell (a1), Henry Dunne (a2), Tharun Zacharia (a3), Katrina Brooker (a4) and Sukhi Shergill (a5)...
  • Please note a correction has been issued for this article.
Summary

The optimal management of autism with psychosis remains unclear. This report describes a 22-year-old man with autism and psychosis who was referred to a tertiary-level specialist psychosis service, following a 6-year history of deterioration in mental health starting around the time of sitting GCSE examinations and an episode of bullying at school. We describe the individualised symptom-based approach that was effective in his treatment.

Declaration of interest

The authors declare no conflict of interest.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      A symptom-based approach to treatment of psychosis in autism spectrum disorder
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      A symptom-based approach to treatment of psychosis in autism spectrum disorder
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      A symptom-based approach to treatment of psychosis in autism spectrum disorder
      Available formats
      ×
Copyright
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommerical-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.
Corresponding author
Correspondence: Dr Victoria Bell, Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London SE5 8AF, UK. Email: victoria.1.bell@kcl.ac.uk
Footnotes
Hide All

Authors should be acknowledged as joint first authors.

Footnotes
References
Hide All
1Nylander, L, Lugnegard, T, Hallerback, MU. Autism spectrum disorders and schizophrenia spectrum disorders in adults: is there a connection? A literature review and some suggestions for future clinical research. Clin Neuropsychiatry J Treat Eval 2008; 5: 4354.
2Owen, MJ, O'Donovan, MC, Thapar, A, Craddock, N. Neurodevelopmental hypothesis of schizophrenia. Br J Psychiatry 2011; 198: 173–5.
3Chisholm, K, Lin, A, Abu-Akel, A, Wood, SJ. The association between autism and schizophrenia spectrum disorders: a review of eight alternate models of co-occurrence. Neurosci Biobehav Rev 2015; 55: 173–83.
4van Dooren, K, McPherson, L, Lennox, N. Mapping the needs of adults with autism and co-morbid intellectual disability. Curr Dev Disord Rep 2016; 3: 82–9.
5Raja, M, Azzoni, A. Autistic spectrum disorders and schizophrenia in the adult psychiatric setting: diagnosis and comorbidity. Psychiatr Danub 2010; 22: 514–21.
6Barneveld, PS, Pieterse, J, de Sonneville, L, van Rijn, S, Lahuis, B, van Engeland, H, et al. Overlap of autistic and schizotypal traits in adolescents with autism spectrum disorders. Schizophr Res 2011; 126: 231–6.
7Bevan, JR, Thapar, A, Lewis, G, Zammit, S. The association between early autistic traits and psychotic experiences in adolescence. Schizophr Res 2012; 135: 164–9.
8North, AS, Russell, AJ, Gudjonsson, GH. High functioning autism spectrum disorders: an investigation of psychological vulnerabilities during interrogative interview. J Forens Psychiatry Psychol 2008; 19: 323–34.
9van Os, J, Hanssen, M, Bijl, RV, Ravelli, A. Strauss (1969) revisited: a psychosis continuum in the general population? Schizophr Res 2000; 45: 1120.
10Lord, C, Rutter, M, Le Couteur, A. Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord 1994; 24: 659–85.
11Fleischhacker, WW, McQuade, RD, Marcus, RN, Archibald, D, Swanink, R, Carson, WH. A double-blind, randomized comparative study of aripiprazole and olanzapine in patients with schizophrenia. Biol Psychiatry 2009; 65: 510–17.
12Mauri, MC, Moliterno, D, Rossattini, M, Colasanti, A. Depression in schizophrenia: comparison of first-and second-generation antipsychotic drugs. Schizophr Res 2008; 99: 712.
13La Grenade, L, Graham, D, Trontell, A. Myocarditis and cardiomyopathy associated with clozapine use in the United States. N Engl J Med 2001; 345: 224–5.
14Taylor, D, Paton, C, Kapur, S. Maudsley Prescribing Guidelines (11th edn). Informa Healthcare, 2012.
15Goodman, WK, Price, LH, Rasmussen, SA, Mazure, C, Fleischmann, RL, Hill, CL, et al. The Yale–Brown Obsessive–Compulsive Scale: development, use, and reliability. Arch Gen Psychiatry 1989; 46: 1006–11.
16Schirmbeck, F, Zink, M. Clozapine-induced obsessive-compulsive symptoms in schizophrenia: a critical review. Curr Neuropharmacol 2012; 10: 8895.
17Samalin, L, Garnier, M, Llorca, PM. Clinical potential of lurasidone in the management of schizophrenia. Ther Clin Risk Manag 2011; 7: 239.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

BJPsych Open
  • ISSN: -
  • EISSN: 2056-4724
  • URL: /core/journals/bjpsych-open
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed

A symptom-based approach to treatment of psychosis in autism spectrum disorder

  • Victoria Bell (a1), Henry Dunne (a2), Tharun Zacharia (a3), Katrina Brooker (a4) and Sukhi Shergill (a5)...
  • Please note a correction has been issued for this article.
Submit a response

eLetters

No eLetters have been published for this article.

×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *