1Canene-Adams, K, Campbell, JK, Zaripheh, S, et al. (2005) The tomato as a functional food. J Nutr 135, 1226–1230.
2Giovannucci, E, Ascherio, A, Rimm, EB, et al. (1995) Intake of carotenoids and retinol in relation to risk of prostate cancer. J Natl Cancer Inst 87, 1767–1776.
3Giovannucci, E (2005) Tomato products, lycopene, and prostate cancer: a review of the epidemiological literature. J Nutr 135, 2030S–2031S.
4Blum, A, Monir, M, Wirsansky, I, et al. (2005) The beneficial effects of tomatoes. Eur J Intern Med 16, 402–404.
5Saganuma, H & Inakuma, T (1999) Protective effect of dietary tomato against endothelial dysfunction in hypercholesterolemic mice. Biosci Biotechnol Biochem 63, 78–82.
6Clinton, SK (1998) Lycopene: chemistry, biology and implications for human health and disease. Nutr Rev 56, 35–51.
7Arab, L & Steck, S (2000) Lycopene and cardiovascular disease. Am J Clin Nutr 71, Suppl. 6, S1691–S1695.
8Di Mascio, P, Kaiser, S & Sies, H (1989) Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Arch Biochem Biophys 274, 532–538.
9Sies, H & Stahl, W (1995) Vitamins E and C, beta-carotene, and other carotenoids as antioxidants. Am J Clin Nutr 62, 1315S–1321S.
10Heber, D & Lu, QY (2002) Overview of mechanisms of action of lycopene. Exp Biol Med (Maywood) 227, 920–923.
11Reifen, R, Nissenkorn, A, Matas, Z, et al. (2004) 5-ASA and lycopene decrease the oxidative stress and inflammation induced by iron in rats with colitis. J Gastroenterol 39, 514–519.
12Bansal, P, Gupta, SK, Ojha, SK, et al. (2006) Cardioprotective effect of lycopene in the experimental model of myocardial ischemia–reperfusion injury. Mol Cell Biochem 289, 1–9.
13Sepodes, B, Maio, R, Pinto, R, et al. (2004) Tempol, an intracelullar free radical scavenger, reduces liver injury in hepatic ischemia–reperfusion in the rat. Transplant Proc 36, 849–853.
14Bonta, IL & Bult, H (1977) Effects of anti-inflammatory drugs on the carrageenin-induced hind paw inflammation of rats deprived of endogenous precursors of prostaglandins. Agents Actions Suppl 2, 77–83.
15Wu, Y, Zhou, C, Song, L, et al. (2006) Effect of total phenolics from Laggera alata on acute and chronic inflammation models. J Ethnopharmacol 108, 243–250.
16Mota-Filipe, H, Sepodes, B, McDonald, MC, et al. (2002) The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat. Med Sci Monit 8, BR444–BR453.
17Moussa, ME, Sarraf, CE, Uemoto, S, et al. (1996) Effect of total hepatic vascular exclusion during liver resection on hepatic ultrastructure. Liver Transpl Surg 2, 461–467.
18Serracino-Inglott, F, Habib, NA & Mathie, RT (2001) Hepatic ischemia–reperfusion injury. Am J Surg 181, 160–166.
19Colletti, LM, Kunkel, SL, Walz, A, et al. (1996) The role of cytokine networks in the local liver injury following hepatic ischemia/reperfusion in the rat. Hepatology 23, 506–514.
20Shirasugi, N, Wakabayashi, G, Shimazu, M, et al. (1997) Up-regulation of oxygen-derived free radicals by interleukin-1 in hepatic ischemia/reperfusion injury. Transplantation 64, 1398–1403.
21Ou, B, Hampsch-Woodill, M & Prior, RL (2001) Development and validation of an improved oxygen radical absorbance capacity assay using fluorescein as the fluorescent probe. J Agric Food Chem 49, 4619–4626.
22Cuzzocrea, S, Riley, DP, Caputi, AP, et al. (2001) Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. Pharmacol Rev 53, 135–159.
23Di Rosa, M, Giroud, JP & Willoughby, DA (1971) Studies on the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine. J Pathol 104, 15–29.
24Khattab, MM (2006) Tempol, a membrane-permeable radical scavenger, attenuates peroxynitrite- and superoxide anion-enhanced carrageenan-induced paw edema and hyperalgesia: a key role for superoxide anion. Eur J Pharmacol 548, 167–173.
25Cuzzocrea, S, Zingarelli, B, Hake, P, et al. (1998) Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation. Free Radic Biol Med 24, 450–459.
26de Groot, H & Rauen, U (2007) Ischemia–reperfusion injury: processes in pathogenetic networks: a review. Transplant Proc 39, 481–484.
27Glantzounis, GK, Salacinski, HJ, Yang, W, et al. (2005) The contemporary role of antioxidant therapy in attenuating liver ischemia–reperfusion injury: a review. Liver Transpl 11, 1031–1047.
28Michael McClain, R & Bausch, J (2003) Summary of safety studies conducted with synthetic lycopene. Regul Toxicol Pharmacol 37, 274–285.