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Effect of a nutritional intervention promoting the Mediterranean food pattern on electrophoretic characteristics of low-density lipoprotein particles in healthy women from the Québec City metropolitan area

  • Julie Goulet (a1), Benoît Lamarche (a1), Amélie Charest (a1), Geneviève Nadeau (a1), Annie Lapointe (a1), Sophie Desroches (a1) and Simone Lemieux (a1)...
Abstract

The objective of the present study was to evaluate the effect of a nutritional intervention promoting the Mediterranean food pattern in free-living conditions on LDL electrophoretic characteristics in a group of seventy-one healthy women, aged between 30 and 65 years. The 12-week nutritional intervention consisted of two courses on nutrition and seven individual sessions with a dietitian. The first course provided information on the Mediterranean food pattern and the second was a cooking lesson. LDL peak particle diameter (LDL-PPD) and cholesterol levels in small (LDL-cholesterol<255?Å) and large LDL fractions (LDL-cholesterol>260?Å) were obtained by 2–16% polyacrylamide gel electrophoresis of whole plasma. The sample was divided on the basis of baseline LDL-PPD using tertiles of the distribution (258·4 Å and 260·0 Å). Among the total sample of women, no significant change in LDL-PPD was observed in response to the nutritional intervention. However, subjects who at baseline were in the first tertile of the LDL-PPD distribution (>258·4 Å) showed a significant increase in LDL-PPD and in the proportion of LDL% >260?%uest;Å in response to the 12-week nutritional intervention (P>0·05). In contrast, LDL-PPD decreased significantly (P=0·007) among women with large LDL particles at baseline (LDL-PPD >260 Å) while the proportion of LDL%<255 Å and of LDL%>260 Å remained unchanged. To conclude, changes in the food pattern, in response to a nutritional intervention promoting the Mediterranean food pattern, were accompanied by beneficial modifications in LDL electrophoretic characteristics in women who were characterised at baseline by smaller LDL particles.

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Corresponding author
*Corresponding author: fax +1 418 656 5877, email Simone.Lemieux@aln.ulaval.ca
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Y Bosse , L Perusse , JP Despres , B Lamarche , YC Chagnon , T Rice , DC Rao , C Bouchard & MC Vohl Evidence for a major quantitative trait locus on chromosome 17q21 affecting low-density lipoprotein peak particle diameter. Circulation (2003) 107, 23612368.

M Burstein & J Samaille On a rapid determination of the cholesterol bound to the serum α- and β-lipoproteins (in French). Clin Chim Acta (1960) 5, 609609.

M de Lorgeril , S Renaud , N Mamelle , P Salen , JL Martin , I Monjaud , J Guidollet , P Touboul & J Delaye Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease.. Lancet (1994) 343, 14541459.

M de Lorgeril , P Salen , JL Martin , I Monjaud ,J Delaye & N Mamelle Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study. Circulation (1999) 99, 779785.

S Moorjani , C Gagné , PJ Lupien & D Brun Plasma triglycerides related decrease in high-density lipoprotein cholesterol and its association with myocardial infarction in heterozygous familial hypercholesterolemia. Metabolism (1986) 35, 311316.

RB Singh , G Dubnov , MA Niaz , S Ghosh , R Singh , SS Rastogi , O Manor , D Pella & EM Berry Effect of an Indo-Mediterranean diet on progression of coronary artery disease in high risk patients (Indo-Mediterranean Diet Heart Study): a randomised single-blind trial. Lancet (2002) 360, 14551461.

A Tchernof , B Lamarche , D Prud'Homme , A Nadeau , S Moorjani , F Labrie , PJ Lupien & JP Despres The dense LDL phenotype. Association with plasma lipoprotein levels, visceral obesity, and hyperinsulinemia in men. Diabetes Care (1996) 19, 629637.

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British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
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