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Plasma concentrations of carotenoids and vitamin C are better correlated with dietary intake in normal weight than overweight and obese elderly subjects

  • Jesús Vioque (a1), Tanja Weinbrenner (a1), Laura Asensio (a1), Adela Castelló (a1), Ian S. Young (a2) and Astrid Fletcher (a3)...
Abstract

Carotenoid and vitamin C intakes, assessed by FFQ, have been positively associated with plasma concentrations in different populations. However, the influence of BMI on these associations has not been explored in detail. We explored in a cross-sectional study the relation between dietary carotenoid and vitamin C intakes, using a 135-item FFQ, with their plasma concentrations by BMI categories in 252 men and 293 women, 65 years and older. For men and women combined, significant (P < 0·05) Pearson correlations were observed between energy-adjusted dietary intakes and plasma concentrations (carotenoids adjusted for cholesterol) for: α-carotene 0·21, β-carotene 0·19, lycopene 0·18, β-cryptoxanthin 0·20 and vitamin C 0·36. Multiple linear regression analyses showed that the intake of carotenoids and vitamin C were significant predictors of their respective plasma concentration (P < 0·01), and that BMI was inversely associated with plasma concentration of carotenoids (P ≤ 0·01) but not with plasma vitamin C. In addition, we observed significant interactions between BMI and the intakes of α-carotene and lutein + zeaxanthin, and to a lower extent β-carotene, suggesting that these intakes in subjects with high BMI were not good predictors of their plasma concentration. The present data suggest that plasma carotenoids and vitamin C may be good markers of dietary intake in elderly subjects, but not so for α-carotene, β-carotene and lutein + zeaxanthin in obese subjects.

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Corresponding author
*Corresponding author: Dr Jesús Vioque, fax +34 965 91 95 51, email vioque@umh.es
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WK Al Delaimy , P Ferrari , N Slimani , (2005) Plasma carotenoids as biomarkers of intake of fruits and vegetables: individual-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC). Eur J Clin Nutr 59, 13871396.

WK Al Delaimy , AL van Kappel , P Ferrari , (2004) Plasma levels of six carotenoids in nine European countries: report from the European Prospective Investigation into Cancer and Nutrition (EPIC). Public Health Nutr 7, 713722.

LF Andersen , DR Jacobs Jr, MD Gross , PJ Schreiner , WO Dale & DH Lee (2006) Longitudinal associations between body mass index and serum carotenoids: the CARDIA study. Br J Nutr 95, 358365.

C Augood , A Fletcher , G Bentham , (2004) Methods for a population-based study of the prevalence of and risk factors for age-related maculopathy and macular degeneration in elderly European populations: the EUREYE study. Ophthalmic Epidemiol 11, 117129.

CA Augood , JR Vingerling , PT de Jong , (2006) Prevalence of age-related maculopathy in older Europeans: the European Eye Study (EUREYE). Arch Ophthalmol 124, 529535.

E Cho , JM Seddon , B Rosner , WC Willett & SE Hankinson (2004) Prospective study of intake of fruits, vegetables, vitamins, and carotenoids and risk of age-related maculopathy. Arch Ophthalmol 122, 883892.

JK Chug-Ahuja , JM Holden , MR Forman , AR Mangels , GR Beecher & E Lanza (1993) The development and application of a carotenoid database for fruits, vegetables, and selected multicomponent foods. J Am Diet Assoc 93, 318323.

DA Cooper , AL Eldridge & JC Peters (1999) Dietary carotenoids and certain cancers, heart disease, and age-related macular degeneration: a review of recent research. Nutr Rev 57, 201214.

NE Craft (1992) Carotenoid reversed-phase high-performance liquid chromatography methods: reference compendium. Methods Enzymol 213, 185205.

P Galan , FE Viteri , S Bertrais , (2005) Serum concentrations of beta-carotene, vitamins C and E, zinc and selenium are influenced by sex, age, diet, smoking status, alcohol consumption and corpulence in a general French adult population. Eur J Clin Nutr 59, 11811190.

HC Hung , KJ Joshipura , R Jiang , (2004) Fruit and vegetable intake and risk of major chronic disease. J Natl Cancer Inst 96, 15771584.

JF Keaney Jr, MG Larson , RS Vasan , (2003) Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study. Arterioscler Thromb Vasc Biol 23, 434439.

AR Mangels , JM Holden , GR Beecher , MR Forman & E Lanza (1993) Carotenoid content of fruits and vegetables: an evaluation of analytic data. J Am Diet Assoc 93, 284296.

JA Mares-Perlman , AI Fisher , R Klein , M Palta , G Block , AE Millen & JD Wright (2001) Lutein and zeaxanthin in the diet and serum and their relation to age-related maculopathy in the third national health and nutrition examination survey. Am J Epidemiol 153, 424432.

JD Morrow (2003) Is oxidant stress a connection between obesity and atherosclerosis? Arterioscler Thromb Vasc Biol 23, 368370.

ME O'Neill , Y Carroll , B Corridan , (2001) A European carotenoid database to assess carotenoid intakes and its use in a five-country comparative study. Br J Nutr 85, 499507.

S Sasaki , F Ushio , K Amano , M Morihara , O Todoriki , Y Uehara & E Toyooka (2000) Serum biomarker-based validation of a self-administered diet history questionnaire for Japanese subjects. J Nutr Sci Vitaminol (Tokyo) 46, 285296.

KJ Scott , DI Thurnham , DJ Hart , SA Bingham & K Day (1996) The correlation between the intake of lutein, lycopene and beta-carotene from vegetables and fruits, and blood plasma concentrations in a group of women aged 50–65 years in the UK. Br J Nutr 75, 409418.

W Smith , P Mitchell , K Webb & SR Leeder (1999) Dietary antioxidants and age-related maculopathy: the Blue Mountains Eye Study. Ophthalmology 106, 761767.

SA Stanner , J Hughes , CN Kelly & J Buttriss (2004) A review of the epidemiological evidence for the ‘antioxidant hypothesis’. Public Health Nutr 7, 407422.

AL van Kappel , JP Steghens , A Zeleniuch-Jacquotte , V Chajes , P Toniolo & E Riboli (2001) Serum carotenoids as biomarkers of fruit and vegetable consumption in the New York Women's Health Study. Public Health Nutr 4, 829835.

R van Leeuwen , S Boekhoorn , JR Vingerling , JC Witteman , CC Klaver , A Hofman & PT de Jong (2005) Dietary intake of antioxidants and risk of age-related macular degeneration. JAMA 294, 31013107.

P van't Veer , MC Jansen , M Klerk & F Kok (2000) Fruits and vegetables in the prevention of cancer and cardiovascular disease. Public Health Nutr 3, 103107.

GM VandenLangenberg , WE Brady , LC Nebeling , G Block , M Forman , PE Bowen , M Stacewicz-Sapuntzakis & JA Mares-Perlman (1996) Influence of using different sources of carotenoid data in epidemiologic studies. J Am Diet Assoc 96, 12711275.

J Vioque & L Gonzalez (1991) Validity of a food frequency questionnaire (preliminary results). Eur J Cancer Prev 1, 1920.

W Willett (1998) Reproducibility and validity of food-frequency questionnaires. In Nutritional Epidemiology, pp. 101147 [W Willet , editor]. New York: Oxford University Press.

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British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
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