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Relation between erythrocyte selenium concentrations and glutathione peroxidase (EC 1.11.1.9) activities of New Zealand residents and visitors to New Zealand

Published online by Cambridge University Press:  09 March 2007

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Abstract

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1. Erythrocyte, plasma and whole blood selenium concentrations and glutathione peroxidase (EC I.11. 1.9; GSHPx) activities were measured (1) in 104 healthy New Zealand residents living in Otago, a low-soil-Se area (2) in sixty-four surgical patients, including nineteen patients on total parenteral nutrition and twenty-three cancer patients (3) in fifty-two ‘overseas subjects’ (twenty-five visitors to Otago from outside New Zealand and twenty-seven Otago residents on return from overseas travel).

2. Blood Se concentrations reflected dietary Se intake; means for Otago patients, healthy subjects and overseas subjects were different (0043, 0.059, 0.136 μg Se/ml blood respectively) and mean for overseas residents was greater than for New Zealand overseas travellers.

3. Erythrocyte Se concentration was always greater than plasma Se, and plasma Se was a smaller pro- portion of erythrocyte Se for patients compared with the controls.

4. GSHPx activities were different in the three groups, and vaned directly with erythrocyte Se until a plateau was reached at approximately 0.14 μg Se/ml erythrocytes.

5. Overseas subjects showed no relationship between erythrocyte Se and GSHPx activity. This agrees with some overseas studies and the significance of this finding is discussed.

6. Plasma Se concentration remained the most sensitive index of short-term changes in Se status, and erythrocyte Se and GSHPx activities for long-term changes in New Zealand subjects. Use of these measure- ments for overseas subjects with higher blood levels is discussed.

Type
Papers of direct relevance to Clinical and Human Nutrition
Copyright
Copyright © The Nutrition Society 1979

References

Allaway, W. H. (1978). In Trace Substances in Environmental Health. vol. 12 [Hemphill, D. D., editor]. Columbia: University of Missouri.Google Scholar
Board, P. G. & Peter, D. W. (1976). Vet. Rec. 99, 14.CrossRefGoogle Scholar
Burk, R. F. (1976). In Proceedings of Symposium on Selenium in the Environment, p. 194. Pittsburgh: Industrial Health Foundation Inc.Google Scholar
Dickson, R. C. & Tomlinson, R. H. (1967). Clin. chim. Acta 16, 311.CrossRefGoogle Scholar
Griffiths, N. M. & Thomson, C. D. (1974). N. Z. med. J. 80, 199.Google Scholar
Hafeman, D. S., Sunde, R. A. & Hoekstra, W. G. (1974). J. Nutr. 104, 580.CrossRefGoogle Scholar
Hoekstra, W. G. (1975). In Trace Substances in Environmental Health, vol. 9, p. 331 [Hemphill, D. D., editor]. Columbia: University of Missouri.Google Scholar
Levine, R. J. & Olson, R. E. (1970). Proc. Soc. exp. Biol. Med. 134, 1030.CrossRefGoogle Scholar
Millar, K. R. (1977). In Trace Elements in Human and Animal Health in New Zealand, p. 84. Hamilton, New Zealand: Waikato University Press.Google Scholar
Paglia, D. E. & Valentine, W. N. (1967). J. lab. clin. Med. 70, 158.Google Scholar
Perona, G., Cellerino, R., Guidi, G. C., Moschini, G., Stievano, B. M. & Tregnaghi, C. (1977). Scand. J. Haematol. 19, 116.CrossRefGoogle Scholar
Reddy, K. & Tappel, A. L. (1974). J. Nutr. 104, 1069.CrossRefGoogle Scholar
Robinson, M. F., Godfrey, P. J., Thomson, C. D., Rea, H. M. & van Rij, A. M. (1979). Am. J. clin. Nutr. (In the Press).Google Scholar
Rudolph, N. & Wong, S. L. (1978). Pediat. Res. 12, 789.CrossRefGoogle Scholar
Schmidt, K. & Heller, W. (1976). Blut 33, 247.CrossRefGoogle Scholar
Schrauzer, G. N. & White, D. A. (1978). Bioinorganic Chem. 8, 303.CrossRefGoogle Scholar
Stewart, R. D. H., Griffiths, N. M., Thomson, C. D. & Robinson, M. F. (1978). Br. J. Nutr. 40, 45.CrossRefGoogle Scholar
Thompson, R. H., McMurray, C. H. & Blanchflower, W. J. (1976). Res. vet. Sci. 20 229.Google Scholar
Thomson, C. D., Rea, H. M., Doesburg, V. M. & Robinson, M. F. (1977). Br. J. Nutr. 37, 457.CrossRefGoogle Scholar
van Rij, A. M., Thomson, C. D., McKenzie, J. M. & Robinson, M. F. (1979). Am. J. clin. Nutr. (In the Press).Google Scholar
Watkinson, J. H. (1966). Analyt. Chem. 32, 981.CrossRefGoogle Scholar
Watkinson, J. H. (1974). N.Z. med. J. 80, 202.Google Scholar
Westermarck, T., Raunu, P., Kirjarinta, M. & Lappalainen, L. (1977). Acta pharmac. tox. 40, 1977.Google Scholar
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