Skip to main content
×
Home
    • Aa
    • Aa
  • Access

Studies with vitamin E and β-carotene as single agents do not prove lack of benefit

  • Raymond A. Firestone (a1)
  • DOI: http://dx.doi.org/10.1017/S0007114507727447
  • Published online: 01 November 2007
  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Studies with vitamin E and β-carotene as single agents do not prove lack of benefit
      Your Kindle email address
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Studies with vitamin E and β-carotene as single agents do not prove lack of benefit
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Studies with vitamin E and β-carotene as single agents do not prove lack of benefit
      Available formats
      ×
Abstract
Copyright
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1S Hercberg , S Czernichow & P Galan (2006) Antioxidant vitamins and minerals in prevention of cancers: lessons from the SU.VI.MAX study. Brit J Nutr 96, S28S30.

2HOPE trial investigators (2005) Effects of long-term vitamin E supplementation on cardiovascular events and cancer. J Am Med Assoc 293, 13381387.

3PF Hu , DB Reuben , EM Crimmins , TB Harris , MH Huang & TE Seeman (2004) The effects of serum β-carotene concentration and burden of inflammation on all-cause mortality risk in high-functioning older persons: MacArthur studies of successful aging. J Gerontol Ser A 59, 849854.

4K Miwa , S Okinaga & M Fujita (2004) Low serum α-tocopherol concentrations in subjects with various coronary risk factors. Circulation J 68, 542546.

5KA Steinmetz & JD Potter (1991) Vegetables, fruit and cancer. I. Epidemiology. Cancer Causes Control 2, 325357.

6R Peto , R Doll , JD Buckley & MB Sporn (1981) Can dietary β-carotene materially reduce human cancer rates? Nature 290, 201208.

7Y Ito , K Wakai , K Suzuki , A Tamakoshi , N Seki , M Ando , Y Nishino & T Ishibashi (2003) Serum carotenoids and mortality from lung cancer: a case-control study nested in the Japan Collaborative Cohort (JACC) study. Cancer Sci 94, 5763.

9PR Taylor (2003) Prospective study of serum vitamin E levels and esophageal and gastric cancers. J Nat Can Inst 95, 1414.

10AT Diplock (1987) Dietary supplementation with antioxidants. Is there a case for exceeding the recommended dietary allowance? Free Rad Biol Med 3, 199–201.

11HOPE trail investigators (2000) Vitamin E supplementation and cardiovascular events in high-risk patients. New Engl J Med 342, 154–160.

12DP Vivekanathan , MS Penn , SK Sapp , A Hsu & EJ Topol (2003) Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomized trials. Lancet 361, 20172023.

13LH Kushi , AR Folsom , RJ Prineas , PJ Mink , Y Wu & RM Bostick (1996) Dietary antioxidant vitamins and death from coronary heart disease in postmenopausal women. New Engl J Med 334, 1156–1162.

14JM Rapola , J Virtamo , S Ripatti , JK Huttunen , D Albanes , PR Taylor & OP Heinonen (1997) Randomised trial of α-tocopherol and β-carotene supplements on incidence of major coronary events in men with previous myocardial infarction. Lancet 349, 17151720.

16AJ Duffield-Lillico & CB Begg (2004) Reflections on the landmark studies of β-carotene supplementation. J Nat Cancer Inst 96, 17291731.

18SJ Weinstein , ME Wright , P Pietinen , I King , C Tan , PR Taylor , J Virtamo & D Albanes (2005) Serum α-tocopherol and γ-tocopherol in relation to prostate cancer risk in a prospective study. J Nat Cancer Inst 97, 396–399.

19KH Wagner , A Kamal-Eldin & I Elmadfa (2004) γ-Tocopherol - an underestimated vitamin? Ann Nutr Metab 48, 169–188.

20KJ Helzlsouer , HY Huang , AJ Alberg , S Hoffman , A Burke , EP Norkus , S Morris & GW Comstock (2000) Association between α-tocopherol, γ-tocopherol, selenium, and subsequent prostate cancer. J Nat Cancer Inst 92, 20182023.

21F Osakada , A Hashino , T Kune , H Katsuki , S Kaneko & A Akaike (2004) α-Tocotrienol provides the most important neuroprotection among vitamin E analogs on cultured striatal neurons. Neuropharmacol 47, 904–915.

22Q Jiang , J Wong , H Fyrst , JD Saba & BN Ames (2004) γ-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis. Proc Nat Acad Sci USA 101, 1782517830.

23RM Tamimi , SE Hankinson , H Campos , D Spiegelman , S Zhang , GA Colditz & WC Willett (2005) Plasma carotenoids, retinol, and tocopherols and risk of breast cancer. Am J Epidemiol 161, 153–160.

24K Sato , E Niki & H Shimasaki (1990) Free radical-mediated chain oxidation of low density lipoprotein and its synergistic inhibition by vitamin E and vitamin C. Arch Biochem Biophys 279, 402405.

25VW Bowry & KU Ingold (1999) The unexpected role of vitamin E (α-tocopherol) in the peroxidation of human low-density lipoprotein. Acc Chem Res 32, 27–34.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×