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A normative study of total scores of the CERAD neuropsychological assessment battery in an educationally diverse elderly population

  • Ji Young Han (a1), Eun Hyun Seo (a2), Dahyun Yi (a1), Bo Kyung Sohn (a3), Young Min Choe (a1), Min Soo Byun (a1), Hyo Jung Choi (a1), Shin Gyeom Kim (a4), Shin Young Park (a5), Jee Wook Kim (a6), Jong Chul Youn (a7), Jin Hyeong Jhoo (a8), Jung Hie Lee (a8), Ki Woong Kim (a9), Jong Inn Woo (a1) and Dong Young Lee (a1)...

Abstract

Background:

This study aimed to investigate the influences of age, education, and gender on the two total scores (TS-I and TS-II) of the Consortium to Establish a Registry for Alzheimer's Disease Neuropsychological assessment battery (CERAD-NP) and to provide normative information based on an analysis for a large number of elderly persons with a wide range of educational levels.

Methods:

In the study, 1,987 community-dwelling healthy volunteers (620 males and 1,367 females; 50–90 years of age; and zero to 25 years of education) were included. People with serious neurological, medical, and psychiatric disorders (including dementia) were excluded. All participants underwent the CERAD-NP assessment. TS-I was generated by summing raw scores from the CERAD-NP subtests, excluding Mini-Mental State Examination and Constructional Praxis (CP) recall subtests. TS-II was calculated by adding CP recall score to TS-I.

Results:

Both TS-I and TS-II were significantly influenced by demographic variables. Education accounted for the greatest proportion of score variance. Interaction effect between age and gender was found. Based on the results obtained, normative data of the CERAD-NP total scores were stratified by age (six overlapping tables), education (four strata), and gender.

Conclusions:

The normative information will be very useful for better interpretation of the CERAD-NP total scores in various clinical and research settings and for comparing individuals’ performance of the battery across countries.

Copyright

Corresponding author

Correspondence should be addressed to: Dr Dong Young Lee, MD, Ph.D., Department of Neuropsychiatry, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, Seoul 110-744, South Korea. Phone: +82.2-2072-2205; Fax: +82.2-744-7241. Email: selfpsy@snu.ac.kr.

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International Psychogeriatrics
  • ISSN: 1041-6102
  • EISSN: 1741-203X
  • URL: /core/journals/international-psychogeriatrics
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