Skip to main content
×
Home
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 10
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Augustinack, Jean C. and van der kouwe, André J.W. 2016. Neuroimaging Part II.


    Zhou, Mengxi Zhang, Feng Zhao, Li Qian, Jin and Dong, Chunbo 2016. Entorhinal cortex: a good biomarker of mild cognitive impairment and mild Alzheimer’s disease. Reviews in the Neurosciences, Vol. 27, Issue. 2,


    Tanner, J. J. Mellott, E. Dunne, E. M. and Price, C. C. 2015. Integrating Neuropsychology and Brain Imaging for a Referral of Possible Pseudodementia: A Case Report. The Clinical Neuropsychologist, Vol. 29, Issue. 2, p. 272.


    Frankó, Edit Insausti, Ana Maria Artacho-Pérula, Emilio Insausti, Ricardo and Chavoix, Chantal 2014. Identification of the human medial temporal lobe regions on magnetic resonance images. Human Brain Mapping, Vol. 35, Issue. 1, p. 248.


    Price, Catherine C. Tanner, Jared J. Schmalfuss, Ilona Garvan, Cynthia Wilson Gearen, Peter Dickey, David Heilman, Kenneth McDonagh, David L. Libon, David J. Leonard, Christiana Bowers, Dawn and Monk, Terri G. 2014. A Pilot Study Evaluating Presurgery Neuroanatomical Biomarkers for Postoperative Cognitive Decline after Total Knee Arthroplasty in Older Adults. Anesthesiology, Vol. 120, Issue. 3, p. 601.


    Tustison, Nicholas J. Cook, Philip A. Klein, Arno Song, Gang Das, Sandhitsu R. Duda, Jeffrey T. Kandel, Benjamin M. van Strien, Niels Stone, James R. Gee, James C. and Avants, Brian B. 2014. Large-scale evaluation of ANTs and FreeSurfer cortical thickness measurements. NeuroImage, Vol. 99, p. 166.


    Hampstead, Benjamin M. and Brown, Gregory S. 2013. Using Neuroimaging to Inform Clinical Practice for the Diagnosis and Treatment of Mild Cognitive Impairment. Clinics in Geriatric Medicine, Vol. 29, Issue. 4, p. 829.


    Troyer, Angela K. Murphy, Kelly J. Anderson, Nicole D. Craik, Fergus I.M. Moscovitch, Morris Maione, Andrea and Gao, Fuqiang 2012. Associative recognition in mild cognitive impairment: Relationship to hippocampal volume and apolipoprotein E. Neuropsychologia, Vol. 50, Issue. 14, p. 3721.


    Wisse, L.E.M. Gerritsen, L. Zwanenburg, J.J.M. Kuijf, H.J. Luijten, P.R. Biessels, G.J. and Geerlings, M.I. 2012. Subfields of the hippocampal formation at 7T MRI: In vivo volumetric assessment. NeuroImage, Vol. 61, Issue. 4, p. 1043.


    Varon, Daniel Loewenstein, David A. Potter, Elizabeth Greig, Maria T. Agron, Joscelyn Shen, Qian Zhao, Weizhao Celeste Ramirez, Maria Santos, Isael Barker, Warren Potter, Huntington and Duara, Ranjan 2011. Minimal Atrophy of the Entorhinal Cortex and Hippocampus: Progression of Cognitive Impairment. Dementia and Geriatric Cognitive Disorders, Vol. 31, Issue. 4, p. 276.


    ×
  • Journal of the International Neuropsychological Society, Volume 16, Issue 5
  • September 2010, pp. 846-855

Entorhinal cortex volume in older adults: Reliability and validity considerations for three published measurement protocols

  • C.C. PRICE (a1) (a2) (a3), M.F. WOOD (a4), C.M. LEONARD (a2) (a5), S. TOWLER (a1), J. WARD (a1), H. MONTIJO (a6), I. KELLISON (a1), D. BOWERS (a1) (a2), T. MONK (a7), J.C. NEWCOMER (a8) and I. SCHMALFUSS (a9) (a10)
  • DOI: http://dx.doi.org/10.1017/S135561771000072X
  • Published online: 01 August 2010
Abstract
Abstract

Measuring the entorhinal cortex (ERC) is challenging due to lateral border discrimination from the perirhinal cortex. From a sample of 39 nondemented older adults who completed volumetric image scans and verbal memory indices, we examined reliability and validity concerns for three ERC protocols with different lateral boundary guidelines (i.e., Goncharova, Dickerson, Stoub, & deToledo-Morrell, 2001; Honeycutt et al., 1998; Insausti et al., 1998). We used three novice raters to assess inter-rater reliability on a subset of scans (216 total ERCs), with the entire dataset measured by one rater with strong intra-rater reliability on each technique (234 total ERCs). We found moderate to strong inter-rater reliability for two techniques with consistent ERC lateral boundary endpoints (Goncharova, Honeycutt), with negligible to moderate reliability for the technique requiring consideration of collateral sulcal depth (Insausti). Left ERC and story memory associations were moderate and positive for two techniques designed to exclude the perirhinal cortex (Insausti, Goncharova), with the Insausti technique continuing to explain 10% of memory score variance after additionally controlling for depression symptom severity. Right ERC-story memory associations were nonexistent after excluding an outlier. Researchers are encouraged to consider challenges of rater training for ERC techniques and how lateral boundary endpoints may impact structure-function associations. (JINS, 2010, 16, 846–855.)

Copyright
Corresponding author
*Correspondence and reprint requests to: Catherine C. Price, Ph.D., Clinical and Health Psychology, 101 S. Newell Drive, PO Box 100165, University of Florida, Gainesville, FL 32610. E-mail: cep23@phhp.ufl.edu
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

P.E. Barta , L. Dhingra , R. Royall , & E. Schwartz (1997). Improving stereological estimates for the volume of structures identified in three-dimensional arrays of spatial data. Journal of Neuroscience Methods, 75, 111118.

P.S. Bellgowan , E.A. Buffalo , J. Bodurka , & A. Martin (2009). Lateralized spatial and object memory encoding in entorhinal and perirhinal cortices. Learning & Memory, 16, 433438.

H. Braak , & E. Braak (1994). Morphological criteria for the recognition of Alzheimer’s disease and the distribution pattern of cortical changes related to this disorder. Neurobiology of Aging, 15, 355360.

H. Braak , & E. Braak (1997). Frequency of stages of Alzheimer-related lesions in different age categories. Neurobiology of Aging, 18, 351357.

E.D. Bigler , E.S. Neeley , M.J. Miller , D.F. Tate , S.A. Rice , H. Cleavinger , . (2004). Cerebral volume loss, cognitive deficit and neuropsychological performance: Comparative measures of brain atrophy: I. Dementia. Journal of the International Neuropsychological Society, 10, 442452.

E.D. Bigler , & D.F. Tate (2001). Brain Volume, intracranial volume, and dementia. Investigative Radiology, 36, 539546.

M.E. Charlson , P. Pompei , K.L. Ales , & C.R. MacKenzie (1987). A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. Journal of Chronic Disorders, 40, 373383.

J. Cohen (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale, NJ: Lawrence Earlbaum Associates.

L. deToledo-Morrell , T.R. Stoub , M. Bulgakova , R.S. Wilson , D.A. Bennett , S. Leurgans , . (2004). MRI derived entorhinal volume is a good predictor of conversion from MCI to AD. Neurobiology of Aging, 25, 11971203.

B.C. Dickerson , E. Fezcko , J.C. Augustinack , J. Pacheco , J.C. Morris , B. Fischl , . (2009). Differential effects of aging and Alzheimer’s disease on medial temporal lobe cortical thickness and surface area. Neurobiology of Aging, 30, 432440.

E. Feczko , J.C. Augustinack , B. Fischl , & B.C. Dickerson (2009). An MRI-based method for measuring volume, thickness and surface area of entorhinal, perirhinal, and posterior parahippocampal cortex. Neurobiology of Aging, 30, 420431.

B. Fischl , A.A. Stevens , N. Rajendran , T. Yeo , D.N. Greve , K. Leemput , . (2009). Predicting the location of entorhinal cortex from MRI. Neuroimage, 47, 817.

M. Folstein , S. Folstein , & P. McHugh (1975). Mini-mental state: A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatry Research, 12, 189198.

I.I. Goncharova , B.C. Dickerson , T.R. Stoub , & L. deToledo-Morrell (2001). MRI of human entorhinal cortex: A reliable protocol for volumetric measurement. Neurobiology of Aging, 22, 737745.

R. Insausti , T. Tunon , T. Sobreviela , A.M. Insausti , & L.M. Gonzalo (1995). The human entorhinal cortex: A cytoarchitectonic analysis. The Journal of Comparative Neurology, 355, 171198.

C.R. Jeukens , M.C. Vlooswijk , H.J. Majoie , M.C. de Krom , A.P. Aldenkamp , P.A. Hofman , . (2009). Hippocampal MRI volumetry at 3 Tesla: Reliability and practical guidance. Investigative Radiology, 44, 509517.

J.R. Landis , & G.G. Koch (1977). The measurement of observer agreement for categorical data. Biometrics, 33, 159174.

M.P. Lawton , & E.M. Brody (1969). Assessment of older people: Self-maintaining and instrumental activities of daily living. Gerontologist, 9, 179186.

J.W. Newcomer , G. Selke , A. Melson , T. Hershey , S. Craft , K. Richards , . (1999). Decreased memory performance in healthy humans induced by stress-level cortisol treatment. Archives of General Psychiatry, 56, 527533.

C. Reitz , A. Brickman , T.R. Brown , J. Manly , C. DeCarli , S.A. Small , . (2009). Linking hippocampal structure and function to memory performance in an aging population. Archives of Neurology, 66, 13851392.

A.C. Rosen , M.W. Prull , J.D. Gabrieli , T. Stoub , R. O’Hara , L. Friedman , . (2003). Differential associations between entorhinal and hippocampal volumes and memory performance in older adults. Behavioral Neuroscience, 117, 11501160.

D.W. Shattuck , & R.M. Leahy (2002). BrainSuite: An automated cortical surface identification tool. Medical Image Analysis, 6, 129142.

S.M. Smith , M. Jenkinson , M.W. Woolrich , C.F. Beckmann , T.E. Behrens , H. Johansen-Berg , . (2004). Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage, 23(Suppl. 1), S208S219.

A. von Gunten , C. Bouras , E. Kovari , P. Giannakopoulos , & P.R. Hof (2006). Neural substrates of cognitive and behavioral deficits in atypical Alzheimer’s disease. Brain Research Reviews, 51, 176211.

Y. Xu , C.R. Jack Jr., P.C. O’Brien , E. Kokmen , G.E. Smith , R.J. Ivnik , . (2000). Usefulness of MRI measures of entorhinal cortex versus hippocampus in AD. Neurology, 54, 17601767.

P.A. Yushkevich , J. Piven , H.C. Hazlett , R.G. Smith , S. Ho , J.C. Gee , . (2006). User-guided 3D active contour segmentation of anatomical structures: Significantly improved efficiency and reliability. Neuroimage, 31, 11161128.

J. Zhan , M. Brys , L. Glodzik , W. Tsui , E. Javier , J. Wegiel , . (2009). An entorhinal cortex sulcal pattern is associated with Alzheimer’s disease. Human Brain Mapping, 30, 874882.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Journal of the International Neuropsychological Society
  • ISSN: 1355-6177
  • EISSN: 1469-7661
  • URL: /core/journals/journal-of-the-international-neuropsychological-society
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: