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The evaluation of potential global morbidity attributable to intestinal nematode infections

  • M. S. Chan (a1), G. F. Medley (a1), D. Jamison (a2) and D. A. P. Bundy (a1)
  • DOI:
  • Published online: 01 April 2009

This paper presents a method of estimating the potential global morbidity due to human intestinal nematode infections (Ascaris lumbricoides, Trichuris trichiura and hookworms), based on the observed prevalence of infection. The method relies on the observed relationships between prevalence and intensity of infection, and between worm burden and potential morbidity. This approach is shown to be sensitive to the precision of the original prevalence estimates and, in particular, to the degree of spatial heterogeneity in levels of infection. The estimates presented here indicate that several tens of millions of children are likely to suffer developmental consequences from infection, and suggest that the global disease burden of geohelminthiasis may be significantly greater than was supposed.

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R. M. Anderson (1982). Transmission dynamics and control of infectious disease agents. In Population Biology of Infectious Diseases (ed. R. M. Anderson & R. M. May ), pp. 149–76. Berlin: Springer.

R. M. Anderson & R. M. May (1985). Helminth infections of humans: mathematical models, population dynamics and control. Advances in Parasitology 24, 1101.

R. M. Anderson & R. M. May (1991). Infectious Diseases of Humans: Dynamics and Control. Oxford: Oxford University Press.

D. A. P. Bundy , S. K. Chandiwana , M. M. A. Homeida , S. Yoon & K. E. Mott (1991). The epidemiological implications of a multi-infection approach to the control of human helminth infections. Transactions of the Royal Society of Tropical Medicine and Hygiene 85, 274–6.

D. A. P. Bundy & E. S. Cooper (1989). Trichuris and trichuriasis in humans. Advances in Parasitology 28, 107–73.

D. A. P. Bundy , E. S. Cooper , D. E. Thompson , J. M. Didier & I. Simmons (1987). Epidemiology and population dynamics of Ascaris lumbricoides and Trichuris trichiura in the same community. Transactions of the Royal Society of Tropical Medicine and Hygiene 81, 987–93.

D. W. T. Crompton (1988). The prevalence of ascariasis. Parasitology Today 4, 162–9.

H. L. Guyatt & D. A. P. Bundy (1991). Estimating prevalence of community morbidity due to intestinal helminths: prevalence of infection as an indicator of the prevalence of disease. Transactions of the Royal Society of Tropical Medicine and Hygiene 85, 778–82.

H. L. Guyatt & D. Evans (1992). Economic considerations for helminth control. Parasitology Today 8, 397402.

R. M. May & R. M. Anderson (1984). Spatial heterogeneity and the design of immunisation programs. Mathematical Bioscience 72, 83111.

C. Nokes , S. M. Grantham-McGregor , A. W. Sawyer , E. S. Cooper & D. A. P. Bundy (1992). Parasitic helminth infection and cognitive function in school children. Proceedings of the Royal Society 247, 7781.

L. Savioli , D. A. P. Bundy & A. M. Tomkins (1992). Intestinal parasitic infections: a soluble public health problem. Transactions of the Royal Society of Tropical Medicine and Hygiene 86, 353–4.

L. S. Stephenson , M. C. Latham , S. N. Kinoti , K. M. Kurz & H. Brigham (1990). Improvements in physical fitness of Kenyan schoolboys infected with hookworm, Trichuris trichiura and Ascaris lumbricoides following a single dose of albendazole. Transactions of the Royal Society of Tropical Medicine and Hygiene 84, 277–82.

S. J. De Vlas & B. Gryseels (1992). Underestimation of Schistosoma mansoni prevalences. Parasitology Today 8, 274–7.

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