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Consequences of plant phenolic compounds for productivity and health of ruminants

Published online by Cambridge University Press:  11 August 2008

Garry C. Waghorn*
Affiliation:
Nutrition and Behaviour, AgResearch, Grasslands Research Centre, Private Bag 11008, Palmers ton North, New Zealand
Warren C. McNabb
Affiliation:
Nutrition and Behaviour, AgResearch, Grasslands Research Centre, Private Bag 11008, Palmers ton North, New Zealand
*
*Corresponding author: Dr Garry Waghorn, fax +64 6351 8003, garry.waghorn@agresearch.co.nz
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Abstract

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Plant phenolic compounds are diverse in structure but are characterised by hydroxylated aromatic rings (e.g. flavan-3-ols). They are categorised as secondary metabolites, and their function in plants is often poorly understood. Many plant phenolic compounds are polymerised into larger molecules such as the proanthocyanidins (PA; condensed tannins) and lignins. Only the lignins, PA, oestrogenic compounds and hydrolysable tannins will be considered here. Lignins slow the physical and microbial degradation of ingested feed, because of resilient covalent bonding with hemicellulose and cellulose, rather than any direct effects on the rumen per se. The PA are prevalent in browse and are expressed in the foliage of some legumes (e.g. Lotus spp.), but rarely in grasses. They reduce the nutritive value of poor-quality diets, but can also have substantial benefits for ruminant productivity and health when improved temperate forages are fed. Beneficial effects are dependent on the chemical and physical structure, and concentration of the PA in the diet, but they have been shown to improve live-weight gain, milk yield and protein concentration, and ovulation rate. They prevent bloat in cattle, reduce gastrointestinal nematode numbers, flystrike and CILt production. Some phenolic compounds (e.g. coumestans) cause temporary infertility, whilst those produced by Fusarium fungi found in pasture, silage or stored grains can cause permanent infertility. The HT may be toxic because products of their metabolism can cause liver damage and other metabolic disorders.

Type
Nutrition and Behaviour Group Symposium on ‘Exploitation of medicinal properties of plants by animals and man through food intake and foraging behaviour’
Copyright
Copyright © The Nutrition Society 2003

References

Adams, NR (1995) Detection of the effects of phytoestrogens in sheep and cattle. Journal of Animal Science 73, 15091515CrossRefGoogle ScholarPubMed
Aerts, RJ, McNabb, WC, Molan, A, Brand, A, Barry, TN & Peters, JS (1999) Condensed tannins from Lotus corniculatus and Lotus pedunculatus exert different effects on the in vitro rumen degradation of ribulose-l,5-bisphosphate carboxylase/oxygenase (Rubisco) protein. Journal of the Science of Food and Agriculture 79, 79853.0.CO;2-K>CrossRefGoogle Scholar
Athanasiadou, S, Kyriazakis, I, Jackson, F & Coop, RL (2000) Consequences of long-term feeding with condensed tannins on sheep parasitised with Trichostrongylus colubriformis. Inter- national Journal for Parasitology 30, 10251033CrossRefGoogle ScholarPubMed
Athanasiadou, S, Kyriazakis, I, Jackson, F & Coop, RL (2001) Direct anthelmintic effect of condensed tannins towards different gastrointestinal nematodes of sheep: in vitro and in vivo studies. Veterinary Parasitology 99, 205219CrossRefGoogle ScholarPubMed
Beddows, AR (1956) Observations on hoove, haven, blown or bloa4 taken from agricultural writings, 1716–1827. Journal of the Agricultural Society 33, 1215Google Scholar
Brooker, JD, O'Donovan, L, Skene, IK & Sellick, G (2000) Mechanisms of tannin resistance and detoxification in the rumen Microbial Biosystems. New Frontiers, Proceedings of the 8th International Symposium on Microbial Ecology 409417 Bell CR Brylinsky M Johnson-Green P Halifax, Canada Atlantic Canada Society for Microbial EcologyGoogle Scholar
Burke, JL, Waghorn, GC & Brookes, IM (2002) An evaluation of sulla (Hedysarum coronarium) with pasture, white clover and lucerne for lambs. New Zealand Society of Animal Production 62, 152156Google Scholar
Cheeke, PR (1998) Natural Toxicants in Feeds, Forages and Poisonous Plants Danville, IL Interstate Publishers IncGoogle Scholar
Cremin, JD, Drackley, JK, Hansen, LR, Grum, DF, Odle, J & Fahey, GC (1995) Effects of glycine and bovine serum albumin on inhibition of propionate metabolism in ovine hepatocytes caused by reduced phenolic monomers. Journal of Animal Science 73, 30093021CrossRefGoogle ScholarPubMed
Douglas, GB, Stienezen, M, Waghorn, GC & Foote, AG (1999) Effect of condensed tannins in birdsfoot trefoil (Lotus corniculatus) and sulla (Hedysarum coronarium) on body weight, carcass fat depth, and wool growth of lambs in New Zealand. New Zealand Journal of Agricultural Research 42, 5564CrossRefGoogle Scholar
Foo, LY, Lu, Y, McNabb, WC, Waghorn, GC & Ulyatt, MJ (1997) Proanthocyanidins from Lotus pedunculatus. Phytochemistry 45, 16891696CrossRefGoogle Scholar
Foo, LY, Newman, R, Waghorn, GC, McNabb, WC & Ulyatt, MJ (1996) Proanthocyanidins from Lotus corniculatus. Phytochemistry 41, 617624CrossRefGoogle Scholar
Grabber, JH, Ralph, J & Hatfield, RD (1998) Ferulate cross-links limit the enzymatic degradation of synthetically lignified primary walls of maize. Journal of the Science of Food and Agriculture 77, 1932003.0.CO;2-A>CrossRefGoogle Scholar
Grundhofer, P, Niemetz, R, Schilling, G & Cross, GG (2001) Biosynthesis and subcellular distribution of hydrolysable tannins. Phytochemistry 57, 915927CrossRefGoogle Scholar
Harris, SL, Clark, DA & Labuyrie, PJ (1998) Birdsfoot trefoil – an alternative legume for New Zealand dairy pastures. Proceedings of the New Zealand Grassland Association 60, 99103CrossRefGoogle Scholar
Hatfield, RD, Jung, HG, Ralph, J, Buxton, DR & Weimer, PJ (1994) A comparison of the insoluble residues produced by the Klason lignin and detergent lignin procedures. Journal of the Science of Food and Agriculture 65, 5158CrossRefGoogle Scholar
Hatfield, RD, Ralph, J & Grabber, JH (1999) Cell wall structural foundations: molecular basis for improving forage digestibilities. Crop Science 39, 2737CrossRefGoogle Scholar
Hoskin, SO, Wilson, PR, Barry, TN, Charleston, WAG & Waghorn, GC (2000) Effect of forage legumes containing condensed tannins on lungworm (Dictyocaulus sp.) and gastrointestinal parasitism in young red deer (Cervus elaphus). Research in Veterinary Science 68, 223230CrossRefGoogle Scholar
Jones, RJ, Meyer, JHF, Bechaz, FM, Stultz, MA, Palmer, B, Van, der & Merwe, G (2001) Comparison of rumen fluid from South African game species and from sheep to digest tanniniferous browse. Australian Journal of Agricultural Research 52, 453460CrossRefGoogle Scholar
Jung, HG (1989) Forage lignins and their effects on fibre digestibility. Agronomy Journal 81, 3338CrossRefGoogle Scholar
Jung, HG, Mertens, DR & Payne, AJ (1997) Correlation of acid detergent lignin and Klason lignin with digestibility of forage dry matter and neutral detergent fibre. Journal of Dairy Science 80, 16221628CrossRefGoogle Scholar
Larkin, PJ, Tanner, GJ, Joseph, RG & Kelman, WM (1999) Modifying condensed tannin content in plants Proceedings of the XVIII International Grasslands Congress, Vol. 3, 167178 Buchanan-Smith JG Bailey LD McCaughey P Calgary, Alta Association Management CentreGoogle Scholar
Leathwick, DM & Atkinson, DS (1995) Dagginess and flystrike in lambs grazed on Lotus corniculatus or ryegrass. Proceedings of the New Zealand Society of Animal Production 55, 196198Google Scholar
Lowry, JB, Conlan, LL, Schlink, AC & McSweeney, CS (1994) Acid detergent dispersible lignin in tropical grasses. Journal of the Science of Food and Agriculture 65, 4149CrossRefGoogle Scholar
Lowry, JB, McSweeney, CS & Palmer, B (1996) Changing perceptions of the effect of plant phenolics on nutrient supply in the ruminant. Australian Journal of Agricultural Research 47, 829842CrossRefGoogle Scholar
Lowry, JB, Sumpter, EA, McSweeney, CS, Schline, AC & Bowden, B (1993) Phenolic acids in the fibre of some tropical grasses, effect on feed quality and their metabolism by sheep. Australian Journal of Agricultural Research 44, 11231133CrossRefGoogle Scholar
McMahon, LR, McAllister, TA, Berg, BP, Majak, W, Acharya, SN, Popp, JD, Coulman, BE, Wang, Y, Cheng, K-J (2000) A review of the effects of forage condensed tannins on ruminal fermentation and bloat in grazing cattle. Canadian Journal of Plant Science 80, 469485CrossRefGoogle Scholar
McNabb, WC, Waghorn, GC, Peters, JS & Barry, TN (1996) The effect of condensed tannins in Lotus pedunculatus on the solubilisation and degradation of ribulose–1,5- bis phosphate carboxylase (EC 4.1.1.39; Rubisco) protein in the rumen and the sites of Rubisco digestion. British Journal of Nutrition 76, 535549CrossRefGoogle Scholar
Min, BR, McNabb, WC, Barry, TN, Kemp, PD, Waghorn, GC & McDonald, MF (1999) The effect of condensed tannins in Lotus corniculatus upon reproductive efficiency and wool production in sheep during late summer and autumn Journal of Agricultural Science, Cambridge 132, 323334CrossRefGoogle Scholar
Molan, AL, Waghorn, GL & McNabb, WC (2002) Effect of condensed tannins on egg hatching and larval development of Trichostrongylus colubriformis in vitro. Veterinary Record 150, 6569CrossRefGoogle ScholarPubMed
Molan, AL, Waghorn, GC, Min, BR & McNabb, WC (2000) The effect of condensed tannins from seven herbages on Trichostrongylus colubriformis larval migration in vitro. Folia Parasitologica 47, 3944CrossRefGoogle ScholarPubMed
Mueller-Harvey, I (2001) Analysis of hydrolysable tannins. Animal Feed Science and Technology 91, 320CrossRefGoogle Scholar
Mueller-Harvey, I & McAllan, AB (1992) Tannins. Their bio- chemistry and nutritional properties Advances In Plant Cell Biochemistry And Biotechnology, Vol. 1, 151217 Morrison IM London JAI Press LtdGoogle Scholar
Niezen, JH, Charleston, WAG, Robertson, HA, Shelton, D, Waghorn, GC & Green, R (2000a) The effect of feeding sulla (Hedysarum coronarium) or lucerne (Medicago sativa) on lamb parasite burdens and development of immunity to gastrointestinal parasites. Veterinary Parasitology 105, 229245CrossRefGoogle Scholar
Niezen, JH, Waghorn, TS, Charleston, WAG & Waghorn, GC (1995) Growth and gastrointestinal nematode parasitism in lambs grazing either lucerne (Medicago sativa) or sulla (Hedysarum coronarium) which contains condensed tannins Journal of Agricultural Science, Cambridge 125, 281289CrossRefGoogle Scholar
Niezen, JH, Waghorn, GC, Graham, T, Carter, JL & Leathwick, DM (2002b) The effect of diet fed to lambs on subsequent development of Trichostrongylus colubriformis larvae in vitro and on pasture. Veterinary Parasitology 105, 269283CrossRefGoogle ScholarPubMed
Ortiz, LT, Alzueta, C, Trevino, J & Castano, M (1994) Effects of faba bean tannins on the growth and histological structure of the intestinal tract and liver of chicks and rats. British Poultry Science 35, 743754CrossRefGoogle ScholarPubMed
Palm, CA & Sanches, PA (1991) Nitrogen release from the leaves of some tropical legumes as affected by their lignin and poly- phenolic contents. Soil Biology and Biochemistry 23, 8388CrossRefGoogle Scholar
Priolo, A, Waghorn, GC, Lanza, M, Biondi, L & Pennisi, P (2000) Polyethylene glycol as a means for reducing the impact of condensed tannins in Carob pulp: Effects on lamb growth performance and meat quality. Journal of Animal Science 78, 810816CrossRefGoogle ScholarPubMed
Reed, JD (1995) Nutritional toxicology of tannins and related polyphenols in forage legumes. Journal of Animal Science 73, 15161528CrossRefGoogle ScholarPubMed
Rittner, U & Reed, JD (1992) Phenolics and in vitro degradability of protein and fibre in west African browse. Journal of the Science of Food and Agriculture 58, 2128CrossRefGoogle Scholar
Robertson, HA, Niezen, JH, Waghorn, GC, Charleston, WAG & Jinlong, M (1995) The effect of six herbages on liveweight gain wool growth and faecal egg count of parasitised ewe lambs. Proceedings of the New Zealand Society of Animal Production 55, 199201Google Scholar
Satter, LD, Jung, HG, Van, Vuuren, AM, Engels FM (1999) Challenges in the nutrition of high producing ruminants Nutritional Ecology Of Herbivores. Proceedings of the Vth International Symposium on the Nutrition of Herbivores 609646 Jung HG Fahey GC Jr Savoy, IL American Society of Animal ScienceGoogle Scholar
Scalbert, A (1991) Antimicrobial properties of tannins. Phyto- chemistry 30, 38753883Google Scholar
Taylor, CE & Murant, AF (1966) Nematicidal activity of aqueous extracts from raspberry canes and roots. Nematologica 12, 488494Google Scholar
Terrill, TH, Rowan, AM, Douglas, GB & Barry, TN (1992) Determination of extractable and bound condensed tannin concentrations in forage plants. Protein concentrate meals and cereal grains. Journal of the Science of Food and Agriculture 58, 321329CrossRefGoogle Scholar
Terrill, TH, Waghorn, GC, Woolley, DJ, McNabb, WC & Barry, TN (1994) Assay and digestion of 14 C-labelled condensed tannins in the gastrointestinal tract of sheep. British Journal of Nutrition 72, 467477CrossRefGoogle Scholar
Waghorn, GC (1996) Condensed tannins and nutrition absorption from the small intestine Proceedings of the 1996 Canadian Society of Animal Science Annual Meeting 175194 Rode LM Lethbridge, Alta Lethbridge Research CentreGoogle Scholar
Waghorn, GC (2002) Can forages match concentrate diets for dairy production?. Proceedings of the New Zealand Society of Animal Production 62, 261266Google Scholar
Waghorn, GC, Adams, NR & Woodfield, DR (2002a) Deleterious substances in grazed pastures Sheep Nutrition 333356 Freer M Dove H Wallingford, Oxon CAB InternationalCrossRefGoogle Scholar
Waghorn, GC, Gregory, NG, Todd, SE & Wesselink, R (1999a) Dags in sheep; a look at faeces and reasons for dag formation. Proceedings of the New Zealand Grassland Association 61, 4349CrossRefGoogle Scholar
Waghorn, GC, Reed, JD & Ndlovu, LR (1999b) Condensed tannins and herbivore nutrition Proceedings of the XVIIth International Grasslands Congress, Vol. 3, 153156 Buchanan-Smith JG Bailey LD McCaughey D Calgary, Alta Association Management CentreGoogle Scholar
Waghorn, GC & Shelton, ID (1997) Effect of condensed tannins in Lotus corniculatus on the nutritive value of pasture for sheep. Journal of Agricultural Science, Cambridge 128, 365372CrossRefGoogle Scholar
Waghorn, GC, Shelton, ID & Thomas, VJ (1989) Particle breakdown and rumen digestion of fresh ryegrass (Lolium perenne L.) and Lucerne (Medicago saliva L.) fed to cows during a restricted feeding period. British Journal of Nutrition 61, 409423CrossRefGoogle Scholar
Waghorn, GC, Tavendale, MH & Woodfield, DR (2002b) Methanogenesis from forages fed to New Zealand ruminants. Proceedings of the New Zealand Grassland Association 64, 167171CrossRefGoogle Scholar
Walton, JP, Waghorn, GC, Plaizier, JC, Birtles, M & McBride, BW (2002) Influence of condensed tannins on gut morphology in sheep fed Lotus pedunculatus. Canadian Journal of Animal Science 81, 605607CrossRefGoogle Scholar
Wang, Y, Douglas, GB, Waghorn, GC, Barry, TN & Foote, AG (1996a) The effect of condensed tannins in Lotus corniculatus upon the lactation performance in ewes Journal of Agricultural Science, Cambridge 126, 353362CrossRefGoogle Scholar
Wang, Y, Waghorn, GC, McNabb, WC, Barry, TN, Hedley, MJ & Shelton, ID (1996b) Effect of condensed tannins in Lotus corniculatus upon the digestion of methionine and cysteine in the small intestine of sheep Journal of Agricultural Science, Cambridge 127, 413421CrossRefGoogle Scholar
Wilson, JR (1993) Organization of forage plant tissues Forage Cell Wall Structure And Digestibility 132 Jung H Buxton D Hatfield R Ralph J Madison, WI American Society of Agronomy IncCrossRefGoogle Scholar
Wilson, JR & Hatfield, RD (1997) Structural and chemical changes of cell types during stem development: consequences for fibre degradation by rumen microflora. Australian Journal of Agricultural Research 48, 165180CrossRefGoogle Scholar
Woodward, SL, Auldist, MJ, Laboyrie, PJ & Jansen, EBL (1999) Effect of Lotus corniculatus and condensed tannins on milk yield and milk composition of dairy cows. Proceedings of the New Zealand Society of Animal Production 54, 152155Google Scholar