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Fish and fish-liver oil consumption in adolescence and midlife and risk of CHD in older women

  • Alfheidur Haraldsdottir (a1) (a2), Johanna E Torfadottir (a1) (a2), Unnur A Valdimarsdottir (a2) (a3), Thor Aspelund (a2) (a4), Tamara B Harris (a5), Lenore J Launer (a5), Vilmundur Gudnason (a4) (a6) and Laufey Steingrimsdottir (a1)...
Abstract
Abstract Objective

To study the association of fish and fish-liver oil consumption across the lifespan with CHD later in life among Icelandic women, with special emphasis on the effects of consumption in adolescence.

Design

Prevalence association study. Logistic regression was used to estimate odds ratios and 95 % confidence intervals of CHD according to fish or fish-liver oil exposure. Models were adjusted for age, education, concurrent diet and other known risk factors.

Setting

The study was nested within the AGES-Reykjavik Study, conducted in Reykjavik, Iceland.

Subjects

Participants were 3326 women aged 66–96 years, with available information on CHD status at entry to the study and information on fish and fish-liver oil consumption during midlife and adolescence. Dietary habits were assessed retrospectively using a validated FFQ.

Results

CHD was identified in 234 (7·9 %) women. Compared with women with no intake of fish-liver oil in adolescence or midlife, women who consumed fish-liver oil at least three times weekly in adolescence or in midlife had a decreased risk of CHD (OR=0·62; 95 % CI 0·45, 0·85 and OR=0·68; 95 % CI 0·50, 0·94, respectively). No associations were observed between fish intake (>2 portions/week v. ≤2 portions/week) in adolescence or midlife and CHD in this population with high fish intake.

Conclusions

Fish-liver oil consumption, from early life, may reduce the risk of CHD in older women. Lifelong nutrition may be of importance in the prevention of CHD in older women.

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*Corresponding author: Email alh1@hi.is
References
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1. Bucher HC, Hengstler P, Schindler C et al. (2002) N-3 polyunsaturated fatty acids in coronary heart disease: a meta-analysis of randomized controlled trials. Am J Med 112, 298304.
2. Harris WS, Kris-Etherton PM & Harris KA (2008) Intakes of long-chain omega-3 fatty acid associated with reduced risk for death from coronary heart disease in healthy adults. Curr Atheroscler Rep 10, 503509.
3. Mozaffarian D & Rimm EB (2006) Fish intake, contaminants, and human health: evaluating the risks and the benefits. JAMA 296, 18851899.
4. Kris-Etherton PM, Harris WS & Appel LJ (2002) Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 106, 27472757.
5. He K, Song Y, Daviglus ML et al. (2004) Accumulated evidence on fish consumption and coronary heart disease mortality: a meta-analysis of cohort studies. Circulation 109, 27052711.
6. Ness AR, Maynard M, Frankel S et al. (2005) Diet in childhood and adult cardiovascular and all cause mortality: the Boyd Orr cohort. Heart 91, 894898.
7. Strom M, Halldorsson TI, Mortensen EL et al. (2012) Fish, n-3 fatty acids, and cardiovascular diseases in women of reproductive age: a prospective study in a large national cohort. Hypertension 59, 3643.
8. Berenson GS, Srinivasan SR, Bao W et al. (1998) Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. N Engl J Med 338, 16501656.
9. Sekikawa A, Steingrimsdottir L, Ueshima H et al. (2012) Serum levels of marine-derived n-3 fatty acids in Icelanders, Japanese, Koreans, and Americans – a descriptive epidemiologic study. Prostaglandins Leukot Essent Fatty Acids 87, 1116.
10. Harris TB, Launer LJ, Eiriksdottir G et al. (2007) Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics. Am J Epidemiol 165, 10761087.
11. Bjornsson G, Bjornsson BO, Davidsson D et al. (1982) Report abc XXIV. Health Survey in the Reykjavik Area—Women. Stages I–II. 1968–69, 1971–72 and 1976–78. Participants, Invitation, Response etc. Reykjavik: The Icelandic Heart Association.
12. Eysteinsdottir T, Gunnarsdottir I, Thorsdottir I et al. (2011) Validity of retrospective diet history: assessing recall of midlife diet using food frequency questionnaire in later life. J Nutr Health Aging 15, 809814.
13. Eysteinsdottir T, Thorsdottir I, Gunnarsdottir I et al. (2012) Assessing validity of a short food frequency questionnaire on present dietary intake of elderly Icelanders. Nutr J 11, 12.
14. Gunnarsdottir I, Gunnarsdottir BE, Steingrimsdottir L et al. (2010) Iodine status of adolescent girls in a population changing from high to lower fish consumption. Eur J Clin Nutr 64, 958964.
15. Steingrimsdottir L, Thorgeirsdottir H & Aegisdottir S (1991) The Diet of Icelanders. National Nutrition Survey 1990. Main Findings. Reykjavik: Icelandic Nutrtion Council.
16. Steingrimsdottir L, Thorgeirsdottir H & Olafsdottir AS (2003) The Diet of Icelanders. Dietary Survey of the Icelandic Nutrition Council 2002. Main Findings. Reykjavik: Icelandic Nutrtion Council.
17. Sigurjonsson J (1943) Survey on Diet and Health in Iceland (1939–1940) . Reykjavik: Icelandic Nutrition Council.
18. Matís (2009) ISGEM. The Icelandic Food Composition Database. http://www.matis.is/ISGEM/en/search/ (accessed September 2013).
19. Tunstall-Pedoe H, Kuulasmaa K, Amouyel P et al. (1994) Myocardial infarction and coronary deaths in the World Health Organization MONICA Project. Registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four continents. Circulation 90, 583612.
20. Mahoney LT, Burns TL, Stanford W et al. (1996) Coronary risk factors measured in childhood and young adult life are associated with coronary artery calcification in young adults: the Muscatine Study. J Am Coll Cardiol 27, 277284.
21. Magnussen CG, Niinikoski H, Juonala M et al. (2012) When and how to start prevention of atherosclerosis? Lessons from the Cardiovascular Risk in the Young Finns Study and the Special Turku Coronary Risk Factor Intervention Project. Pediatr Nephrol 27, 14411452.
22. Mozaffarian D (2008) Fish and n-3 fatty acids for the prevention of fatal coronary heart disease and sudden cardiac death. Am J Clin Nutr 87, issue 6, 1991S1996S.
23. Anderson JL, May HT, Horne BD et al. (2010) Relation of vitamin D deficiency to cardiovascular risk factors, disease status, and incident events in a general healthcare population. Am J Cardiology 106, 963968.
24. Hsia J, Heiss G, Ren H et al. (2007) Calcium/vitamin D supplementation and cardiovascular events. Circulation 115, 846854.
25. Gunnarsdottir I, Tomasson H, Kiely M et al. (2008) Inclusion of fish or fish oil in weight-loss diets for young adults: effects on blood lipids. Int J Obes (Lond) 32, 1105–1012.
26. Kromhout D, Bosschieter EB & de Lezenne Coulander C (1985) The inverse relation between fish consumption and 20-year mortality from coronary heart disease. New Engl J Med 312, 12051209.
27. Oomen CM, Feskens EJ, Rasanen L et al. (2000) Fish consumption and coronary heart disease mortality in Finland, Italy, and The Netherlands. Am J Epidemiol 151, 9991006.
28. Erkkila AT, Schwab US, de Mello VD et al. (2008) Effects of fatty and lean fish intake on blood pressure in subjects with coronary heart disease using multiple medications. Eur J Nutr 47, 319328.
29. Mozaffarian D, Lemaitre RN, Kuller LH et al. (2003) Cardiac benefits of fish consumption may depend on the type of fish meal consumed: the Cardiovascular Health Study. Circulation 107, 13721377.
30. Aspelund T, Thorgeirsson G, Sigurdsson G et al. (2007) Estimation of 10-year risk of fatal cardiovascular disease and coronary heart disease in Iceland with results comparable with those of the Systematic Coronary Risk Evaluation project. Eur J Cardiovasc Prev Rehabil 14, 761768.
31. Dwyer JT & Coleman KA (1997) Insights into dietary recall from a longitudinal study: accuracy over four decades. Am J Clin Nutr 65, 4 Suppl., 1153S1158S.
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Public Health Nutrition
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