Book contents
- The Genetics of African Populations in Health and Disease
- Cambridge Studies in Biological and Evolutionary Anthropology
- The Genetics of African Populations in Health and Disease
- Copyright page
- Contents
- Contributors
- 1 Reflections on Conceptualizing Africa for Biological Studies with a Historical Component
- 2 History and Genetics in Africa
- 3 Disease, Selection, and Evolution in the African Landscape
- 4 Genetic Susceptibility to Visceral Leishmaniasis
- 5 Genetics of Infection in Sub-Saharan Africa
- 6 Pharmacogenomics and Infectious Diseases in Africa
- 7 A Glimpse into Pharmacogenomics in Africa
- 8 Genomics of Cardiometabolic Disorders in Sub-Saharan Africa
- 9 Breast Cancer in African Populations
- 10 Sociobiological Transition and Cancer
- 11 The Genetic Epidemiology of Orphan Diseases in North Africa
- 12 Birth Defects and Genetic Disease in Sub-Saharan Africa
- 13 Neurogenetic Disorders in Africa: Hereditary Spastic Paraplegia
- 14 Enabling Genomic Revolution in Africa
- Index
- References
9 - Breast Cancer in African Populations
Published online by Cambridge University Press: 02 December 2019
Book contents
- The Genetics of African Populations in Health and Disease
- Cambridge Studies in Biological and Evolutionary Anthropology
- The Genetics of African Populations in Health and Disease
- Copyright page
- Contents
- Contributors
- 1 Reflections on Conceptualizing Africa for Biological Studies with a Historical Component
- 2 History and Genetics in Africa
- 3 Disease, Selection, and Evolution in the African Landscape
- 4 Genetic Susceptibility to Visceral Leishmaniasis
- 5 Genetics of Infection in Sub-Saharan Africa
- 6 Pharmacogenomics and Infectious Diseases in Africa
- 7 A Glimpse into Pharmacogenomics in Africa
- 8 Genomics of Cardiometabolic Disorders in Sub-Saharan Africa
- 9 Breast Cancer in African Populations
- 10 Sociobiological Transition and Cancer
- 11 The Genetic Epidemiology of Orphan Diseases in North Africa
- 12 Birth Defects and Genetic Disease in Sub-Saharan Africa
- 13 Neurogenetic Disorders in Africa: Hereditary Spastic Paraplegia
- 14 Enabling Genomic Revolution in Africa
- Index
- References
Summary
Breast cancer is the second most common form of malignant neoplasia in the world, with an estimated 1.67 million new cancer cases diagnosed in 2012, accounting for 25 percent of all cancers (Ferlay et al. 2013). It is the most frequently diagnosed type of cancer in women in both the developed and less developed regions. The biological and pathological diversity of this disease as influenced by distinct phenotypes, differences in prognosis, and mixed responses to treatment limit the progress to reduce the burden of this disease (Kestler et al. 2011). Thus, the incidence of breast cancer is rising in many parts of the world, especially in developing countries. Breast cancer does not manifest equally in various regions of the world. Its incidence is higher in North America and Northern and Western Europe compared to Southern Europe, and lowest in Africa and Asia (Ferlay et al. 2013).
- Type
- Chapter
- Information
- The Genetics of African Populations in Health and Disease , pp. 199 - 216Publisher: Cambridge University PressPrint publication year: 2019
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