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Chapter 14 - Prophylaxis for Fetal Growth Restriction: Nitric Oxide Donors and Sildenafil

from Section 4 - Prophylaxis and Treatment

Published online by Cambridge University Press:  23 July 2018

Christoph Lees
Affiliation:
Imperial College London
Gerard H. A. Visser
Affiliation:
Universiteit Utrecht, The Netherlands
Kurt Hecher
Affiliation:
University Medical Centre, Hamburg
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Publisher: Cambridge University Press
Print publication year: 2018

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References

Kaufmann, P, Black, S, Huppertz, B. Endovascular trophoblast invasion: Implications for the pathogenesis of intrauterine growth retardation and preeclampsia. Biol Reprod 2003;69(1):17.Google Scholar
Myatt, L. Review: Reactive oxygen and nitrogen species and functional adaptation of the placenta. Placenta 2010;31 Suppl:S66–69.Google Scholar
Krause, BJ, Hanson, MA, Casanello, P. Role of nitric oxide in placental vascular development and function. Placenta 2011;32(11):797805.CrossRefGoogle ScholarPubMed
De Pace, V, Chiossi, G, Facchinetti, F. Clinical use of nitric oxide donors and L-arginine in obstetrics. J Matern Fetal Neonatal Med 2007;20(8):569–79.Google Scholar
Govers, R, Rabelink, TJ. Cellular regulation of endothelial nitric oxide synthase. Am J Physiol Renal Physiol 2001;280(2):F193–206.Google Scholar
Lowe, DT. Nitric oxide dysfunction in the pathophysiology of preeclampsia. Nitric Oxide 2000;4(4):441–58.Google Scholar
Bird, IM, Zhang, L, Magness, RR. Possible mechanisms underlying pregnancy-induced changes in uterine artery endothelial function. Am J Physiol Regul Integr Comp Physiol 2003;284(2):R245–58.CrossRefGoogle ScholarPubMed
Johnson, MR, Anim-Nyame, N, Johnson, P, Sooranna, SR, Steer, PJ. Does endothelial cell activation occur with intrauterine growth restriction? BJOG 2002;109(7):836–9.Google Scholar
Pisaneschi, S, Strigini, FA, Sanchez, AM, Begliuomini, S, Casarosa, E, Ripoli, A, Ghirri, P, Boldrini, A, Fink, B, Genazzani, AR, Coceani, F, Simoncini, T. Compensatory feto-placental upregulation of the nitric oxide system during fetal growth restriction. PLoS One 2012;7(9):e45294.Google Scholar
Meher, S, Duley, L. Nitric oxide for preventing pre-eclampsia and its complications. Cochrane Database Syst Rev 2007;(2):CD006490.Google ScholarPubMed
Mills, TA, Wareing, M, Bugg, GJ, Greenwood, SL, Baker, PN. Chorionic plate artery function and Doppler indices in normal pregnancy and intrauterine growth restriction. Eur J Clin Invest 2005;35(12):758–64.Google Scholar
Sweeney, M, Wareing, M, Mills, TA, Baker, PN, Taggart, MJ. Characterisation of tone oscillations in placental and myometrial arteries from normal pregnancies and those complicated by pre-eclampsia and growth restriction. Placenta 2008;29(4):356–65.CrossRefGoogle ScholarPubMed
Wu, G, Bazer, FW, Satterfield, MC, Li, X, Wang, X, Johnson, GA, Burghardt, RC, Dai, Z, Wang, J, Wu, Z. Impacts of arginine nutrition on embryonic and fetal development in mammals. Amino Acids 2013;45(2):241–56.Google Scholar
Neri, I, Mazza, V, Galassi, MC, Volpe, A, Facchinetti, F. Effects of L-arginine on utero-placental circulation in growth-retarded fetuses. Acta Obstet Gynecol Scand 1996;75:208–12.Google Scholar
Neri, I, Marietta, M, Piccinini, F, Volpe, A, Facchinetti, F. The L-arginine-nitric oxide system regulates platelet aggregation in pregnancy. J Soc Gynecol Invest 1998;5(4):192–6.Google ScholarPubMed
Sieroszewski, P, Suzin, J, Karowicz-Bilińska, A. Ultrasound evaluation of intrauterine growth restriction therapy by a nitric oxide donor (L-arginine). J Matern Fetal Neonatal Med 2004;15(6):363–6.Google Scholar
Xiao, XM, Li, LP. L-arginine treatment for asymmetric fetal growth restriction. Int J Gynaecol Obstet 2005;88(1):1518.CrossRefGoogle ScholarPubMed
Winer, N, Branger, B, Azria, E, Tsatsaris, V, Philippe, HJ, Rozé, JC, Descamps, P, Boog, G, Cynoper, L, Darmaun, D. L-arginine treatment for severe vascular fetal intrauterine growth restriction: A randomized double-bind controlled trial. Clin Nutr 2009;28(3):243–8.Google Scholar
Ramsay, B, de Belder, A, Campbell, S, Moncada, S, Martin, JF. A nitric oxide donor improves uterine artery diastolic blood flow in normal early pregnancy and in women at high risk of pre-eclampsia. Eur J Clin Invest 1994;24(1):76–8.Google Scholar
Kähler, C, Schleussner, E, Möller, A, Seewald, HJ. Nitric oxide donors: Effects on fetoplacental blood flow. Eur J Obstet Gynecol Reprod Biol 2004;115(1):1014.Google Scholar
Lees, C, Valensise, H, Black, R, Harrington, K, Byiers, S, Romanini, C, Campbell, S. The efficacy and fetal-maternal cardiovascular effects of transdermal glyceryl trinitrate in the prophylaxis of pre-eclampsia and its complications: A randomized double-blind placebo-controlled trial. Ultrasound Obstet Gynecol 1998;12(5):334–8.Google Scholar
Barsoum, IB, Renaud, SJ, Graham, CH. Glyceryl trinitrate inhibits hypoxia-induced release of soluble fms-like tyrosine kinase-1 and endoglin from placental tissues. Am J Pathol 2011;178(6):2888–96.CrossRefGoogle ScholarPubMed
Schleussner, E, Lehmann, T, Kähler, C, Schneider, U, Schlembach, D, Groten, T. Impact of the nitric oxide-donor pentaerythrityl-tetranitrate on perinatal outcome in risk pregnancies: A prospective, randomized, double-blinded trial. J Perinat Med 2014;42(4):507–14.Google Scholar
Daiber, A, Wenzel, P, Oelze, M, Münzel, T. New insights into bioactivation of organic nitrates, nitrate tolerance and cross-tolerance. Clin Res Cardiol 2008;97(1):1220.Google Scholar
Read, MA, Giles, WB, Leitch, IM, Boura, AL, Walters, WA. Vascular responses to sodium nitroprusside in the human fetal-placental circulation. Reprod Fertil Dev 1995;7(6):1557–61.CrossRefGoogle ScholarPubMed
Koopmans, CM, Blaauw, J, Van Pampus, MG, Rakhorst, G, Aarnoudse, JG. Abnormal endothelium-dependent microvascular dilator reactivity in pregnancies complicated by normotensive intrauterine growth restriction. Am J Obstet Gynecol 2009;200(1):66.e1–6.CrossRefGoogle ScholarPubMed
Zoma, WD, Baker, RS, Clark, KE. Effects of combined use of sildenafil citrate (Viagra) and 17beta-estradiol on ovine coronary and uterine hemodynamics. Am J Obstet Gynecol 2004;190(5):1291–7.Google Scholar
Wareing, M, Myers, JE, O’Hara, M, Baker, PN. Sildenafil citrate (Viagra) enhances vasodilatation in fetal growth restriction. J Clin Endocrinol Metab 2005;90(5):2550–5.CrossRefGoogle ScholarPubMed
Dastjerdi, MV, Hosseini, S, Bayani, L. Sildenafil citrate and uteroplacental perfusion in fetal growth restriction. J Res Med Sci 2012;17(7):632–6.Google Scholar
Miller, SL, Loose, JM, Jenkin, G, Wallace, EM. The effects of sildenafil citrate (Viagra) on uterine blood flow and well being in the intrauterine growth-restricted fetus. Am J Obstet Gynecol 2009;200(1):102.e1–7.CrossRefGoogle ScholarPubMed
Nassar, AH, Masrouha, KZ, Itani, H, Nader, KA, Usta, IM. Effects of sildenafil in Nω-nitro-L-arginine methyl ester-induced intrauterine growth restriction in a rat model. Am J Perinatol 2012;29(6):429–34.Google ScholarPubMed
Ganzevoort, W, Alfirevicz, Z, von Dadelszen, P, Kenny, L, Papageorghiou, A, van Wassenaer-Leemhuis, A, Gluud, C, Mol, BW, Baker, PN. STRIDER: Sildenafil Therapy In Dismal prognosis Early-onset intrauterine growth Restriction – a protocol for a systematic review with individual participant data and aggregate data meta-analysis and trial sequential analysis. Syst Rev 2014;3:23.CrossRefGoogle ScholarPubMed

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