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Chapter 13 - Neuropathic Pain

Published online by Cambridge University Press:  13 October 2018

By
Elina Zakin  and
David M. Simpson
Edited by
Krishnan Padmakumari Sivaraman Nair ,
Marlís González-Fernández  and
Jalesh N. Panicker
Krishnan Padmakumari Sivaraman Nair
Affiliation:
Royal Hallamshire Hospital, Sheffield
Marlís González-Fernández
Affiliation:
Johns Hopkins University Hospital, Baltimore, MD
Jalesh N. Panicker
Affiliation:
National Hospital for Neurology & Neurosurgery, London
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Type
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Information
Neurorehabilitation Therapy and Therapeutics , pp. 144 - 157
Publisher: Cambridge University Press
Print publication year: 2018

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References

Treede, R, Jensen, T, et al. Neuropathic pain: Redefinition and a grading system for clinical and research purposes. Neurology 2008; 70(18): 1630–5.Google Scholar
Woolf, CJ, American College of Physicians, American Physiological Society. Pain: Moving from symptom control toward mechanism-specific pharmacologic management. Ann. Intern. Med. 2004; 140(6): 441–51.CrossRefGoogle ScholarPubMed
Horowitz, SH. The Diagnostic Workup of Patients with Neuropathic Pain. Med. Clin. N. Am. 2007; 91: 21–30.Google Scholar
Simpson, DM, McArthur, JC, Dworkin, RH. Neuropathic pain: Mechanisms, diagnosis and treatment. Oxford, UK: Oxford University Press, 2012.Google Scholar
von Hehn, CA, Baron, R, Woolf, CJ. Deconstructing the neuropathic pain phenotype to reveal neural mechanisms. Neuron. 2012; 73(4): 638–52.Google ScholarPubMed
Chaplan, SR, Guo, HQ, Lee, DH, et al. Neuronal hyperpolarization-activated pacemaker channels drive neuropathic pain. J. Neurosci. 2003; 23(4): 1169–78.Google Scholar
Simpson, DM, Brown, S, Tobias, J. NGX-4010 C107 Study Group. Controlled trial of high-concentration capsaicin patch for treatment of painful HIV neuropathy. Neurology 2008; 70(24): 2305–13.Google Scholar
Woolf, CJ. Central sensitization: Implications for the diagnosis and treatment of pain. Pain 2011; 152(3 Suppl.): S2–S15.Google Scholar
Nitzan-Luques, A, Devor, M, Tal, M. Genotype-selective phenotypic switch in primary afferent neurons contributes to neuropathic pain. Pain 2011; 152(10): 2413–26.Google Scholar
Scholz, J, Broom, DC, Youn, DH, et al. Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury. J. Neurosci. 2005; 25(32): 7317–23.Google Scholar
Ji, RR, Berta, T, Nedergaard, M. Glia and pain: Is chronic pain a gliopathy? Pain 2013; 154(Suppl. 1): S10–S28.Google Scholar
Bouhassira, D, Attal, N. Diagnosis and assessment of neuropathic pain: The saga of clinical tools. Pain 2011; 152(Suppl. 3): S74–S83.CrossRefGoogle ScholarPubMed
Backonja, MM, Galer, BS. Pain assessment and evaluation of patients who have neuropathic pain. Neurol. Clin. 1998; 16(4): 775–90.Google Scholar
Suarez, GA, Dyck, PJ. Quantitative sensory assessment. In Dyck, PJ, Thomas, PK eds. Diabetic neuropathy (2nd edn.). Philadelphia, PA: W. B. Saunders, 1999.Google Scholar
Galantino, ML, Lucci, SL. Living with chronic pain: Exploration of complementary therapies and impact on quality of life. In Wittnick, H, Michel, TH eds. Chronic pain management for physical therapists (2nd edn.). Boston, MA: Butterworth-Heinemann, 2002; 279–91.Google Scholar
Hall, J, et al. Does aquatic exercise relieve pain in adults with neurologic or musculoskeletal disease? A systematic review and meta-analysis of randomized controlled trials. Arch. Phys. Med. Rehabil. 2008; 89(5): 873–83.Google Scholar
Bernaards, CM, et al. The effective of a work style intervention and a lifestyle physical activity intervention on the recovery from neck and upper limb symptoms in computer workers. Pain 2007; 132(1–2): 142–53.Google Scholar
McBeth, J, et al. Cognitive behavior therapy, exercise or both for treating chronic widespread pain. Arch. Intern. Med. 2012; 172(1): 48.Google Scholar
Walsh, DM, Basford, JR. Transcutaneous electrical nerve stimulation, chapter 47. In Smith, HS. ed. Current therapy in pain. Philadelphia, PA: Saunders/Elsevier, 2009; 541–6.Google Scholar
Patil, S., et al. The role of acupuncture in pain management. Curr. Pain Headache Rep. 2016; 20(4): 22.Google Scholar
Dorfman, D, George, MC, Schnir, J, Simpson, DM, Davidson, G, Montgomery, G. Hypnosis for treatment of HIV neuropathic pain: A preliminary report. Pain Med. 2013; 14(7): 1048–56.Google Scholar
Dworkin, , et al. Recommendations for the pharmacological management of neuropathic pain: An overview and literature update. Mayo Clin. Proc. 2010; 85(3): S3–14.Google Scholar
Kremer, M, et al. Antidepressants and gabapentinoids in neuropathic pain: Mechanistic insights. Neuroscience 2016; S0306-4522(16): 30296–2.Google Scholar
Gilron, , et al. Morphine, gabapentin, or their combination for neuropathic pain. N. Engl. J. Med. 2005; 352: 1324–34.Google Scholar
Dworkin, , et al. Pharmacological management of neuropathic pain: Evidence-based recommendations. Pain 2007; 132(3): 237–51.Google Scholar
Rowbotham, MC, et al. Venlafaxine extended release in the treatment of painful diabetic neuropathy: A double-blind, placebo-controlled study. Pain 2004; 100: 697–706.Google Scholar
Fava, , et al. Emergency of adverse events following discontinuation of treatment with extended-release venlafaxine. Am. J. Psychiatry 1997; 154: 1760–2.Google Scholar
Caterina, MJ. Vanilloid receptors take a TRP beyond the sensory afferent. Pain 2003; 105: 5–9.Google Scholar
Capsaicin Study Group. Effect of treatment with capsaicin on daily activities of patients with painful diabetic neuropathy. Diabetes Care 1992; 15:159–65.Google Scholar
Gibbons, CH, et al. Capsaicin induces degeneration of cutaneous autonomic nerve fibers. Ann. Neurol. 2010; 68(6): 888–98.Google Scholar
Simpson, DM, Robinson-Papp, J, Van, J, et al. Capsaicin 8% patch in painful diabetic peripheral neuropathy: A randomized, double-blind, placebo-controlled study. J Pain. 2017; 18(1): 42–53.Google Scholar
Cheung, H, Kamp, D, Harris, E. An in vitro investigation of the action of lamotrigine on neuronal voltage-activated sodium channels. Epilepsy Res. 1992; 13: 309–24.Google Scholar
Raskin, P, Donofrio, PD, Rosenthal, NR, et al. Topiramate vs placebo in painful diabetic neuropathy: Analgesic and metabolic effects. Neurology 2004; 63: 865–73.Google Scholar
Shank, RP, Gardocki, JF, Streeter, AJ, et al. An overview of the preclinical aspects of topiramate pharmacology, pharmacokinetics, and mechanism of action. Epilepsia 2000; 41(Suppl.): S3–9.CrossRefGoogle ScholarPubMed
Perucca, E, Bialer, M. The clinical pharmacokinetics of the newer antiepileptic drugs. Focus on topiramate, zonisamide and tiagabine. Clin. Pharmacokinet. 1996; 31: 29–46.CrossRefGoogle ScholarPubMed
Dogra, S, Beydoun, S, Mazzola, J, et al. Oxcarbazepine in painful diabetic neuropathy: A randomized, placebo-controlled study. Eur. J. Pain. 2005; 9: 543–54.Google Scholar
McLean, MJ, Schmutz, M, Wamil, AW, et al. Oxcarbazepine: Mechanism of action. Epilepsia 1994; 35(Suppl. 3): S5–9.Google Scholar
Rull, JA, Quibrera, R, Gonzalez-Millan, H, et al. Symptomatic treatment of peripheral diabetic neuropathy with carbamazepine (Tegretol): Double blind crossover trial. Diabetologia 1969; 5: 215–18.Google Scholar
Wiffen, PJ, McQuay, HJ, Moore, RA. Carbamazepine for acute and chronic pain. Cochrane Database Syst. Rev. 2005; CD005451.Google Scholar
Gilron, I, et al. Morphine, gabapentin, or their combination for neuropathic pain. N. Engl. J. Med. 2005; 352: 1324–34.Google Scholar
Jones, D, Story, DA. Serotonin syndrome and the anesthetist. Aneasth. Intensive Care 2005; 33: 181–7.Google Scholar
Lionberger, R. General principles for evaluating the abuse deterrence of generic solid oral opioid drug products: Guidance for industry. Food and Drug Administration Center for Drug Evaluation and Research (CDER). www.federalregister.gov/documents/2017/11/22/2017-25248/general-principles-for-evaluating-the-abuse-deterrence-of-generic-solid-oral-opioid-drug-products.Google Scholar
Finnerup, NB, et al. Algorithm for neuropathic pain treatment: An evidence based proposal. Pain 2005; 188: 289–305.Google Scholar
Vranken, JH, et al. Pregabalin in patients with central neuropathic pain: A randomized, double-blind, placebo-controlled trial of a flexible-dose regimen. Pain 2008; 136: 150–7.CrossRefGoogle ScholarPubMed
Gilron, I, Tu, D, et al. Combination of morphine with notriptyline for neuropathic pain. Pain 2015; 156(8): 1440–8.Google Scholar
O’Connor, AB, et al. Pain associated with multiple sclerosis: Systematic review and proposed classification. Pain 2008; 137: 96–111.Google Scholar
Wallace, MS, Marcotte, TD, Umlauf, A, Gouaux, B, Atkinson, JH. Efficacy of inhaled cannabis on painful diabetic neuropathy. J. Pain. 2015; 16(7): 616–27.Google Scholar
Accident Compensation Corporation. Interventional guidelines for pain management. www.acc.co.nz/for-providers/clinical-best-practice/interventional-pain-management/interventions/intervention-index/WCM1.034233.Google Scholar
Pasqualucci, A, Pasqualucci, V, Galla, F, et al. Prevention of post-herpetic neuralgia: Acyclovir and prednisolone versus epidural local anesthetic and methylprednisolone. Acta Anaesthesiol. Scand. 2000; 44: 910–18.CrossRefGoogle ScholarPubMed
Ji, G, Niu, J, Hou, L, Lu, Y, Xiong, L. The effectiveness of repetitive paravertebral injections with local anesthetics and steroids for the prevention of postherpetic neuralgia in patients with acute herpes zoster. Anesth. Analg. 2009; 109: 1651–5.Google Scholar
Van Wijck, AJ, Opstelten, W, et al. The PINE study of epidural steroids and local anaesthetics to prevent postherpetic neuralgia: A randomized controlled trial. Lancet 2006; 367: 219–24.Google Scholar
Rijsdijk, M, Van Wijck, AJ, et al. No beneficial effect of intrathecal methylprednisolone acetate in postherpetic neuralgia patients. Eur. J. Pain. 2013; 17: 714–23.Google Scholar
Kim, YH, Lee, CJ, et al. Effect of pulsed radiofrequency for postherpetic neuralgia. Acta Anaesthesiol. Scand. 2008; 52: 1140–3.Google Scholar
Dworkin, R, O’Connor, A, et al. Interventional management of neuropathic pain: NeuPSIG Recommendations. Pain 2013; 154: 2249–61.Google Scholar
de Vos, CC, Rajan, V, et al. Effect and safety of spinal cord stimulation for treatment of chronic pain caused by diabetic neuropathy. J. Diabetes Complications 2009; 23: 40–5.Google Scholar
Papuc, E, Rejdak, K. The role of neurostimulation in the treatment of neuropathic pain. Ann. Agric. Environ. Med. 2013; 1: 14–17.Google Scholar
Cruccu, G, et al. EFNS guidelines on neurostimulation therapy for neuropathic pain. Eur. J. Neurol. 2007; 14(9): 952–70.Google Scholar
Lee, CH, Delton, AL. Prognostic ability of Tinel Sign in determining outcome for decompression surgery in diabetic and nondiabetic neuropathy. Ann. Plast. Sug. 2004; 53: 523–7.Google Scholar
Stokvis, A, Van der Avoort, DJ, et al. Surgical management of neuroma pain: A prospective follow-up study. Pain 2010; 151: 862–9.Google Scholar
Anderson, VC, Burchiel, KJ. A prospective study of long-term intrathecal morphine in the management of chronic nonmalignant pain. Neurosurgery 1999; 44: 289–300.Google Scholar
Cetas, JS, Saedi, T, Burchiel, KJ. Destructive procedures for the treatment of nonmalignant pain: A structured literature review. J. Neurosurg. 2008; 109: 389–404.Google Scholar
Rivera Dia, RC, Lotero, MAA, et al. Botulinum toxin for the treatment of chronic pain: Review of evidence. Colomb. J. Anesthesiol. 2014; 42(3): 205–13.Google Scholar
Sim, WS. Application of botulinum toxin in pain management. Korean J. Pain. 2011; 24(1): 1–6.Google Scholar
Yin, S, Stucker, FJ, Nathan, CA. Clinical application of botulinum toxin in otolaryngology, head and neck practice (brief review). J. La. State Med. Soc. 2001; 153(2): 92–7.Google Scholar
Aoki, KR. Review of a proposed mechanism for the antinociceptive action of botulinum toxin type A. NeuroToxicology 2005; 26(5): 785–93.Google Scholar
Emad, MR, Emad, M, Taheri, P. The efficacy of intradermal injection of botulinum toxin in patients with post-herpetic neuralgia. Iran Red Crescent Med. J. 2011; 13(5): 323–7.Google Scholar
Ngeow, WC, Nair, R. Injection of botulinum toxin type A (BOTOX) into trigger zone of trigeminal neuralgia as a means to control pain. Oral Surg. Med. Oral Pathol. Oral Radiol. Endod. 2010; 109(3): e47–50.Google Scholar
Ranoux, D, Attal, N, et al. Botulinum toxin type A induces direct analgesic effects in chronic neuropathic pain. Ann. Neurol. 2008; 64(3): 274–83.Google Scholar

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