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Chap 28 - MALIGNANT MESOTHELIOMA AND OTHER MESOTHELIAL PROLIFERATIONS

Published online by Cambridge University Press:  01 March 2011

By
Markku Miettinen
Edited by
Markku Miettinen
Markku Miettinen
Affiliation:
Armed Forces Institute of Pathology, Washington DC
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Summary

Benign mesothelial tumors and malignant mesothelioma are important soft tissue tumors that can present at various sites in the body cavities, and the latter also presents as metastatic tumors in the peripheral soft tissues.

The tumor formerly called a fibrous mesothelioma or localized fibrous tumor is a mesenchymal, fibroblastic, nonmesothelial tumor and is now known as a solitary fibrous tumor. This tumor is unrelated to mesothelioma and is included in Chapter 12.

ADENOMATOID TUMOR

An adenomatoid tumor is a benign mesothelial proliferation that is best known for its occurrence in the internal female and male genitalia: the uterus, fallopian tubes, and epididymis, but it can occur almost anywhere around the serosal surfaces, both in the abdominal and thoracic cavities. It is not uniformly agreed whether an adenomatoid tumor is a benign neoplasm or a form of localized mesothelial hyperplasia.

Clinical Features

Adenomatoid tumors are usually detected in young to middle-aged adults, often incidentally during surgery or imaging studies for unrelated conditions. The most common sites in women are the fallopian tube and uterus, where a small 1-cm to 2-cm adenomatoid tumor is not an uncommon finding in a hysterectomy specimen. In a unique case, an adenomatoid tumor involved the uterus diffusely in a renal transplant patient. Involvement of the ovary has been rarely reported.

In men, the epididymis is the most common site, but the spermatic cord or tunica albuginea can also be involved.

Type
Chapter
Information
Modern Soft Tissue Pathology
Tumors and Non-Neoplastic Conditions
 , pp. 811 - 833
Publisher: Cambridge University Press
Print publication year: 2010

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References

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