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Accacoeliid digeneans associated with fish of the family Molidae exhibit enigmatically high taxonomic diversity. However, the phylogenetic relationships between species within this digenean taxon are poorly understood. In the present study, the first nuclear 28S rRNA gene, ITS2 region of nuclear DNA, and mitochondrial cox1 gene sequence datasets were obtained for two members of the Accacoeliidae, a type and only species of the genus Odhnerium Yamaguti 1934 and an unidentified Accacladocoelium sp. collected from Mola mola (Linnaeus, 1758) off Iturup Island. Analyses of molecular differentiation and phylogenetic relationships indicate that Accacladocoelium sp. is a sister species to Accacladocoelium nigroflavum (Rudolphi, 1819). The genus Odhnerium is closely related to Tetrochetus Looss, 1912, on the 28S rRNA gene-based phylogenetic tree. Results of phylogenetic analysis based on both the mitochondrial cox1 gene and the concatenated ribosomal ITS2 region and cox1 gene of mtDNA show that the genus Odhnerium is close to the A. nigroflavum + Accacladocoelium sp. clade. In turn, the genus Accacladocoelium does not have monophyletic status in the trees reconstructed from these data.
The global population and status of Snowy Owls Bubo scandiacus are particularly challenging to assess because individuals are irruptive and nomadic, and the breeding range is restricted to the remote circumpolar Arctic tundra. The International Union for Conservation of Nature (IUCN) uplisted the Snowy Owl to “Vulnerable” in 2017 because the suggested population estimates appeared considerably lower than historical estimates, and it recommended actions to clarify the population size, structure, and trends. Here we present a broad review and status assessment, an effort led by the International Snowy Owl Working Group (ISOWG) and researchers from around the world, to estimate population trends and the current global status of the Snowy Owl. We use long-term breeding data, genetic studies, satellite-GPS tracking, and survival estimates to assess current population trends at several monitoring sites in the Arctic and we review the ecology and threats throughout the Snowy Owl range. An assessment of the available data suggests that current estimates of a worldwide population of 14,000–28,000 breeding adults are plausible. Our assessment of population trends at five long-term monitoring sites suggests that breeding populations of Snowy Owls in the Arctic have decreased by more than 30% over the past three generations and the species should continue to be categorised as Vulnerable under the IUCN Red List Criterion A2. We offer research recommendations to improve our understanding of Snowy Owl biology and future population assessments in a changing world.
Phylogenetic studies of aberrant species are of considerable scientific interest because their taxonomic rank in traditional systems based on morphological characters is not infrequently overestimated. Apopharynx bolodes (Braun, 1902) is one of the few psilostomid digeneans devoid of the pharynx. This is considered a sufficient basis for assigning it and similar species to the subfamily Apopharynginae. We found A. bolodes in Fulica atra Linnaeus, 1758 from Belarus, described it morphologically, and genotyped it by the 28S rRNA gene and the ITS2 region. It is the first molecular data on A. bolodes and the first record of this digenean species in Belarus. The phylogenetic analysis based on partial sequences of the 28S rRNA gene showed that A. bolodes is closely related to the Sphaeridiotrema spp. (Sphaeridiotrematinae). However, this phylogenetic inference has not received yet support with data on the ITS2 region.
The Cyathocotylidae Mühling, 1898 is a family of primitive diplostomoid trematodes important for understanding the evolution of the superfamily Diplostomoidea. However, cyathocotylids remain poorly studied with the use of molecular techniques. In this study we sequenced the 5.8S + ITS2 region, 28S rRNA, and cox1 genes of two cyathocotylid species and obtained new morphological data on them. We propose Georduboisia nom. nov. instead of the preoccupied name Duboisia Szidat, 1936 (junior homonym of Duboisia Stremme, 1911). Adults of Georduboisia cf. teganuma (Ishii, 1935) and Paracoenogonimus ovatus Katsurada, 1914 were collected from fish-eating birds in the south of the European part of Russia. Georduboisia cf. teganuma was very similar to G.teganuma but differed from it in the shape of the testes. The 28S rRNA gene dataset provided the best-resolved phylogeny of the Cyathocotylidae to date. In the phylogram based on partial sequences of this gene, P. ovatus was close to members of Holostephanoides Dubois, 1983, Neogogatea Chandler & Rausch, 1947 and Gogatea Szidat, 1936. Georduboisia cf. teganuma clustered with members of Cyathocotyle Mühling, 1896 and Holostephanus Szidat, 1936. Phylogenetic analysis based on the 5.8S + ITS2 dataset showed that adults of P. ovatus examined in our study were conspecific with the metacercariae from the musculature of fish collected in Hungary and Italy. It also revealed probable misidentifications of larvae and adults of cyathocotylids whose sequences are deposited in GenBank NCBI.
The genus Ancyrocephalus sensu lato is a large assemblage of species of dactylogyrid monopisthocotyleans without clear taxonomic boundaries. Despite an urgent need for revision, only three representatives of this taxon have been molecularly characterised so far. We found specimens of Ancyrocephalus curtus, a previously non-genotyped species, in gills of Perccottus glenii caught in the River Syumnyur, Amur Basin, Russia. The aim of this study was to assess the phylogenetic position of this parasite using partial sequences of 28S rRNA gene. In the phylogenetic tree, A. curtus appeared as a sister taxon to the dactylogyrine genus Gobioecetes. The new molecular evidence supports the hypothesis about the non-monophyletic status of Ancyrocephalus sensu lato.
Podocotyle is a genus of marine opecoelid digeneans that parasitize a wide variety of fish as adults. We present the first phylogenetic analysis of several Podocotyle isolates using nuclear 28S rDNA and mitochondrial cox1 DNA regions. New sequences were obtained for Podocotyle specimens from fish caught in the Sea of Okhotsk and the White Sea. Based on morphological and molecular data, eight Podocotyle lineages of species rank were revealed. However, this diversity is poorly formalized within the current taxonomic model of the genus. As a result, we identified Podocotyle cf. angulata, Podocotyle cf. atomon, Podocotyle cf. reflexa, Podocotyle atomon of Sokolov et al., 2019, Podocotyle sp. of Denisova et al., 2023, Podocotyle sp. 1, Podocotyle sp. 2 and Podocotyle sp. 3. We also highlight the unresolved question of the life cycles of representatives of Podocotyle whose intramolluscan stages parasitize the intertidal snails Littorina spp.
The COVID-19 outbreak is a serious global public health issue with wide-ranging negative effects on people’s lives, which is reflected in steadily rising mental health problems. In order to appropriately respond to the increased occurrence of psychiatric illness, protect mental health and strengthen resilience it is necessary to include new technologies, such as extended reality (XR) or socially assistive robots (SAR) in not only psychiatric treatment but also in the prevention of psychiatric diseases. In this context, the use of new technologies offers innovative ways to strengthen resilience, self-efficacy and stress coping skills and plays an important role in improving psychological wellbeing.
Objectives
Preliminary results from studies at the Clinical Department of Psychiatry and Psychotherapeutic Medicine in Graz, Austria, dealing with new technologies in psychiatry, show new options for psychiatric settings.
Methods
Project AMIGA: The aim of this study is to test the effectiveness of a cognitive training session, conducted with the SAR named Pepper. In this randomized controlled trial, the effectiveness of SAR on depressive symptoms and correlates is evaluated in a sample of 60 individuals with major depression. While the intervention group will receive cognitive training with the SAR Pepper, the control group will receive “treatment-as-usual” therapy with a common PC software. Participants will receive 30 minutes of training 2 times per week over a period of 3 weeks.
Project XRes4HEALTH: The aim of this study is to develop an XR resilience training to increase resilience and stress coping mechanisms in healthcare workers. A total of 40 people will be included. To test the effectiveness of the resilience training, 3 XR training sessions of 15 minutes each will be held. A pre-post measurement will test the effectiveness of the training on wellbeing and stress levels as well as the acceptance and satisfaction with the training.
Project AI-REFIT: The overall goal of this study is to explore key information to increase resilience in healthy individuals who are at increased risk for mental health problems. Through a usability study, the artificial intelligence-based prototype app of the resilience training will be tested for acceptance, usability, functionality, and efficiency. During the resilience training, participants are wearing a smartwatch which measures psychophysiological parameters. Conclusions about the success of the therapy can be drawn based on digital data acquisition.
Results
New technologies including XR and SAR support classical psychiatric treatment in the topics of resilience and cognitive training as an add-on therapy in times of reduced availability of healthcare workers.
Conclusions
The rapid development of new technologies holds a lot of potential in the treatment of psychiatric disorders, which is why it is important to scientifically evaluate those innovative tools.
The norms of labor law that regulate the relevant relationship between the employee and the employer are constantly evolving under the influence of various factors, including society and the State. Labor law trends have become especially prominent over the past several years, particularly during the COVID-19 pandemic. Lockdown restrictions have dealt a serious blow to the labor field and have required urgent action from both companies and governments. In view of this, a number of relevant subtopics have been formed in labor relations, the study of which is of interest to the entire scientific community. The purpose of the research paper is to study the main trends that have emerged in modern labor law and their impact on the formation of the labor legislation system in Ukraine and the European Union (EU) from a comparative perspective. The article analyzes the main directions that the authors have identified as especially relevant in the development of labor relations and the legal regulation of such issues. Considering that some trends have arisen spontaneously under the influence of the COVID-19 pandemic, and many States were not ready for them, we have analyzed how the legislator settled such issues. The laws of Ukraine, the EU, and individual EU member States are examined here in a comparative perspective to draw upon and understand a complete picture of the modern development of labor relations in Europe and to identify the most beneficial approaches to regulating topical issues of labor law. The information obtained as a result of the study can be used to improve Ukraine's national legislation, bring it in line with European standards, further study the issue of the modern development of labor relations, and teach and develop methodological support for educational disciplines related to labor law and social security law.
The nematode Mooleptus rabuka is recorded in the digestive tract of catshark Apristurus fedorovi caught at the Imperial Ridge (Pacific Ocean). Important morphological features such as the number of cephalic and caudal papillae, the position of amphids and the shape of the gubernaculum are detailed in this parasite species. According to the phylogenetic analyses based on the 18S ribosomal RNA gene sequences, M. rabuka forms a lineage, Mooleptinae nom. nov., which is close to the gnathostomatid genus Echinocephalus (maximum likelihood analysis), or else forms a polytomy with this genus and the lineages of Anguillicola + Spiroxys and Tanqua + ‘Linstowinema’ sp. (Bayesian inference analysis). Overall, our findings do not support the monophyly of the Gnathostomatidae. We elevate spiroxyines to the family status, Spiroxyidae stat. nov., and temporarily consider the Gnathostomatidae to include the following subfamilies: Ancyracanthinae Yorke & Maplestone, 1926, Gnathostomatinae Railliet, 1895 sensu lato and Mooleptinae nom. nov. The name Mooleptinae nom. nov. is suggested instead of the Metaleptinae Moravec & Nagasawa, 2000, which is based on a preoccupied generic name Metaleptus Machida, Ogawa & Okiyama, 1982.
The topic of research was phenomenon of impaired age self-consciousness in non-psychotic latent schizophrenia patients defined.
Objectives
To explore features of impaired age self-identity and to determine syndromic affiliation of the syndrome in comparison with premorbid personality disorders traits.
Methods
The study sample comprised 141 patients with latent schizophrenia (pseudo neurotic (F21.3 - 64.5%, 91 patients), coenesthopathic (F20.8 - 25.5%, 36 patients) and pseudo psychopathic (F21.4, - 9.9%, 14 patients)) aged 16-31 (average 22.1 years old) in 2007-2019. A follow-up, experimental psychological and clinical study was conducted.
Results
The onset of impaired age self-identity was dominated by a radical drop of the subjective age in self-conscious mind of the patients accompanied by a tormented feeling of loss of self-dependence, role autonomy, helplessness, inability of decision making and to be answerable. Patients described this sudden condition as a loss of ‘maturity feeling’ and return to the juvenile perception of self. In a delusive and unclear manner, phrases such as ‘I feel inferior to others as if a helpless child among adults’, ‘I feel as if my childhood is back’ were uttered. Excessive worrying and enlivening of childhood memories were also included. This correlates to occurrence of humble and sometimes dependent/avoidant behavior, feeling of helplessness and fear with respect to caring for one self, rising subordination and suggestibility.
Conclusions
This phenomenon of regress to earlier ontogenetic level of personal development reported as impaired age self-consciousness can thus be regarded as an obligate form of depersonalization in patients with latent schizophrenia.
Covering our faces with masks, due to COVID-19 pandemic safety regulations, we can no longer fully rely on the social signals we are used to. We have to read what’s between the lines. This is already difficult for healthy individuals, but may be particularly challenging for individuals with neuropsychiatric conditions.
Objectives
Our main goal was to examine (i) whether capabilities in body and face language reading are connected to each other in healthy females and males; and (ii) whether capabilities to body/face language reading are related to other social abilities.
Methods
Healthy females and males accomplished a task with point-light body motion portraying angry and neutral locomotion along with a task with point-light faces expressing happiness and angriness. They had to infer emotional content of displays. As a control condition, perceivers were administered with the RMET-M (Reading the Mind in the Eyes Test, Modified) with static images.
Results
Females excelled on inferring emotions from body locomotion. Moreover, only in females, inferring emotions from body and face were firmly linked, whereas in males, face reading was connected to performance on the RMET-M.
Conclusions
The outcome points to gender-specific modes in social cognition: females rely upon merely dynamic cues in facial and bodily displays, whereas males most likely trust configural information. The findings are of value for investigation of face/body language reading in neuropsychiatric conditions, most of which are gender specific.
According to previous studies, about 8,8-14,5% cases of schizophrenia is comorbid to type 2 diabetes. The focus of the study was the evaluation and dynamics of positive and negative symptoms in case of combination of the diseases.
Objectives
100 patients were divided in two groups: 48 patients was assigned to receive a monotherapy treatment with antipsychotic; 52 patients received the combination of antipsychotics, nootropics and antioxidants. The efficiency criterion was the dynamics of the questionnaire The quality of life of patients SF- 36, Hamilton’s scale of Depression and anxiety, overall score on a scale for evaluation positive and negative symptoms (PANSS).
Methods
After treatment the physical component of health is 41,38% in the first group and 56,34% in the second group (p≤ 0,05). The psychical component of health is 39,79% in the first group and 50,8% in the second group (p≤ 0,05). Also statistically confirmed (p≤ 0,05) in the patients of the second group the improvement on the Hamilton’s scale of Depression and anxiety questionnaire and PANSS.
Results
After treatment the physical component of health is 41,38% in the first group and 56,34% in the second group (p≤ 0,05). The psychical component of health is 39,79% in the first group and 50,8% in the second group (p≤ 0,05). Also statistically confirmed (p≤ 0,05) in the patients of the second group the improvement on the Hamilton’s scale of Depression and anxiety questionnaire and PANSS.
Conclusions
According to Quality of Life questionnaire combination of antipsychotic, nootropic, antioxidant is significant more effective than treatment only with antipsychotic.
Research on face tuning is of particular relevance during the Covid-19 pandemic leading to social isolation and anxiety, but also requiring social integrity. Face sensitivity represents an essential component of social competence. This ability is aberrant in most neuropsychiatric conditions. Studies in typically developing individuals enable to develop new tools for examination and better understanding non-verbal social cognition in neuropsychiatry.
Objectives
Here we used a novel set of Face-n-Thing images to address the following issues: (i) whether the ability to seeing faces in non-face images (face pareidolia) is affected by gender; and (ii) whether it is altered with changing display orientation. The main advantage of Face-n-Thing images is that face tuning occurs without being explicitly fostered by familiar elements.
Methods
A newly developed Face-n-Thing task, on which images were shown either with canonical upright orientation or inverted 180º in the image plane, was administered to healthy females and males. On each trial, they have to indicate whether they have a face impression.
Results
Face impression was substantially impeded by display inversion in both males and females. With upright display orientation, no gender differences were found, whereas with inversion, Face-n-Thing images elicited face impression in females significantly more often.
Conclusions
The findings open a way for examination of face sensitivity and underwriting brain networks in neuropsychiatric conditions, most of which are gender-specific. Display inversion represents a proper control for face tuning in neuroimaging studies. Gender differences should be taken into account when conceiving studies in neuropsychiatric populations.
The current COVID-19 pandemic brings social isolation to our daily lives that may elevate depression. The impact of major depressive disorder (MDD) on social cognitive functioning is far from understood, but essential for prevention and treatment of this neuropsychiatric condition.
Objectives
Our aim was to examine (i) whether face tuning is lower in depression; and (ii) how it is related to other cognitive abilities (such as perceptional organization). Furthermore, we intended to clarify gender impact on face tuning in MDD, as twice more females are affected.
Methods
Using a recently developed paradigm, the Face-n-Food task, we examined face tuning in 26 patients with MDD and 26 person-by-person matched controls. The advantage of non-face images is that its single elements do not promote face processing.
Results
Strikingly, MDD individuals showed intact face tuning. As sex ratio in our patient sample was about 2:1 (as in MDD population in general), we recruited additional male patients and found that MDD male patients were as good as female patients. Yet, while face tuning in MDD patients showed a significant correlation with perceptual organization abilities, in controls, it was linked with social cognition.
Conclusions
The outcome suggests that the origins of aberrant social functioning in MDD lie in maladaptive cognitive schemas rather than in a lack of sensitivity towards social signals per se. To elucidate neural circuits involved in face tuning in MDD, a magnetoencephalography (MEG) study with the Face-n-Food images is currently under progress.
Persons in Arctic regions disproportionately experience depression. Knowledge gaps remain regarding factors associated with depression among adolescents in the Northwest Territories (NWT), Canada, where child and adolescent mental health hospitalizations are nearly 2.5 times the national rate. This study assesses correlates of depression among adolescents in the NWT.
Methods
We conducted a cross-sectional survey with adolescents aged 13–18 in 17 NWT communities. We assessed associations between socio-demographic characteristics, dating violence, food insecurity and depression, measured with the 9-item Patient Health Questionnaire. We conducted ordered logistic regressions to assess associations with no, mild, or moderate/severe depression scores.
Results
Participants (n = 399; mean age: 14.3, s.d.: 1.3) were mostly Indigenous (79%) and 45% reported food insecurity. Nearly half (47%) reported minimal/no depression symptoms, 25% mild symptoms and 28% moderate/severe symptoms. In multivariate analyses, participants who were cisgender women compared to other genders, sexually diverse v. heterosexual, and food insecure had double the odds of more severe depression symptoms. Among those dating, dating violence was associated with double the odds of moderate/severe depression symptoms.
Conclusions
Findings support tailored interventions to address material (food insecurity), relational (dating violence) and symbolic (gender and sexual orientation norms) contextual factors associated with depression among adolescents in the NWT.
Identifying a need for developing a conceptual framework for the future development of Food-Based Dietary Guidelines (FBDG) in Europe, The Federation of European Nutrition Sciences established a Task Force for this purpose. A workshop was held with the specific objective to discuss the various dimensions considered as particularly relevant. Existing frameworks for FBDG were discussed, and presentations from various countries illustrated not only several commonalities but also a high degree of heterogeneity in the guidelines from different countries. Environmental aspects were considered in several countries, and dimensions like food safety, dietary habits and preparation were included in others. The workshop provided an overview of the use of FBDG – both in developing front-of-pack nutrition labels and for reformulation and innovation. The European FBDG dimensions were described with examples from the close connection between FBDG and European Union (EU) policies and activities and from the compilation of a database of national FBDG. Also, the challenges with communication of FBDG were discussed. Considering the current scientific basis and the experiences from several countries, the Task Force discussed the various dimensions of developing FBDG and concluded that environmental aspects should be included in the future conceptual framework for FBDG. A change in terminology to sustainable FDBG (SFBDG) could reflect this. The Task Force concluded that further work needs to be done exploring current practice, existing methodologies and the future prospects for incorporating other relevant dimensions into a future Federation of European Nutrition Societies conceptual framework for SFBDG in Europe and working groups were formed to address that.
In 2004 Atserias, Kolaitis, and Vardi proposed $\text {OBDD}$-based propositional proof systems that prove unsatisfiability of a CNF formula by deduction of an identically false $\text {OBDD}$ from $\text {OBDD}$s representing clauses of the initial formula. All $\text {OBDD}$s in such proofs have the same order of variables. We initiate the study of $\text {OBDD}$ based proof systems that additionally contain a rule that allows changing the order in $\text {OBDD}$s. At first we consider a proof system $\text {OBDD}(\land , \text{reordering})$ that uses the conjunction (join) rule and the rule that allows changing the order. We exponentially separate this proof system from $\text {OBDD}(\land )$ proof system that uses only the conjunction rule. We prove exponential lower bounds on the size of $\text {OBDD}(\land , \text{reordering})$ refutations of Tseitin formulas and the pigeonhole principle. The first lower bound was previously unknown even for $\text {OBDD}(\land )$ proofs and the second one extends the result of Tveretina et al. from $\text {OBDD}(\land )$ to $\text {OBDD}(\land , \text{reordering})$.
In 2001 Aguirre and Vardi proposed an approach to the propositional satisfiability problem based on $\text {OBDD}$s and symbolic quantifier elimination (we denote algorithms based on this approach as $\text {OBDD}(\land , \exists )$ algorithms). We augment these algorithms with the operation of reordering of variables and call the new scheme $\text {OBDD}(\land , \exists , \text{reordering})$ algorithms. We notice that there exists an $\text {OBDD}(\land , \exists )$ algorithm that solves satisfiable and unsatisfiable Tseitin formulas in polynomial time (a standard example of a hard system of linear equations over $\mathbb {F}_2$), but we show that there are formulas representing systems of linear equations over $\mathbb {F}_2$ that are hard for $\text {OBDD}(\land , \exists , \text{reordering})$ algorithms. Our hard instances are satisfiable formulas representing systems of linear equations over $\mathbb {F}_2$ that correspond to checksum matrices of error correcting codes.
Depression is one of the most common mental health problem and it grows greater every year around the world.
Aims
The main aims were to analyze the possibility of using functional and structural neuroimaging methods in diagnosis of different depression types and to find the predictors of pharmacological resistance.
Materials & methods
46 patients with depression syndrome were distributed into 3 groups: 1) Neurotic Depression (Diagnosis: Adjustment disorders) - ND group; 2) Endogenous Depression (Diagnosis: Recurrent Depression, Bipolar Affective Disorder - current depressive episode, Schizoaffective disorder, depressive type) - PD group, 3) Depression due to organic pathology (Diagnosis: Organic depressive disorder, Organic mixed affective disorder) - OD group. Controls were 18 years old- and gender-matched healthy participants. We used several methods of functional (positron-emission tomography, functional magnetic resonance imaging) and structural (voxel-based morphometry, diffusion-tensor imaging) neuroimaging.
Results
We found several functional and structural abnormalities in limbic structures within all three groups. Some of them were the same, some were different. Also we found several functional and structural predictors of pharmacological resistance.
Conclusions
We found several functional and structural abnormalities in all three depressive groups. Almost all of them were parts of so-called frontal-subcortical circuits, dysfunction of which, according to the present knowledge, could play crucial role in depression pathogenesis.
Summarizing our own results and analyzing the data of our colleagues, we complement a theory of depression pathogenesis and propose an original point of view for neurobiological basis of different types of depressive disorders and its pharmacological resistance.