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He Rourou Whai Painga, an Aotearoa New Zealand Dietary Pattern for Metabolic Health and Whānau Wellbeing: Protocol for a randomised controlled trial
- F.E. Lithander, A. Braakhuis, R. Gearry, T. Merry, M. Foster, C. Ross, A. Parry Strong, J. Krebs, D. Conroy, A. Rolleston, M. Weatherall, J. Mullaney
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- Journal:
- Proceedings of the Nutrition Society / Volume 83 / Issue OCE1 / April 2024
- Published online by Cambridge University Press:
- 07 May 2024, E166
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Cardiometabolic diseases are highly prevalent in Aotearoa New Zealand(1). Dietary intake is a modifiable risk factor for such diseases and certain dietary patterns, specifically the Mediterranean diet (MedDiet), are associated with improved metabolic health(2). This study aims to test whether an intervention of a Mediterranean dietary pattern incorporating high quality New Zealand foods (NZMedDiet pattern) using behaviour change science can improve the metabolic health of participants and their household/whānau. This is a multi-centre, three-stage trial, with two randomised controlled trials (RCTs), both parallel groups, superiority trials, and a longitudinal cohort study. The first RCT (RCT1) is a comparison of the NZMedDiet pattern implemented using behaviour science compared to usual diet for 12 weeks, and the second (RCT2) is a behaviour-change intervention compared to no intervention for 12 weeks, administered after participants have been exposed to the intervention in RCT1. The third stage is a longitudinal cohort study where all participants are followed for up to a year. The primary outcome measure for each stage is the metabolic syndrome severity score (MetSSS). Two hundred index participants and their household/whānau have been recruited and randomised into the trial. Participants are from four centres, two of which are University research units (University of Auckland (n = 57) and University of Otago, Christchurch (n = 60)), one a community-based traditional meeting place (Tu¯ Kotahi Māori Asthma and Research Trust at Ko¯kiri Marae in Lower Hutt, Wellington (n = 19)), and the other based at a hospital-based research unit (the Centre for Endocrine Diabetes and Obesity Research (CEDOR) in Wellington (n = 64). The trial will test whether the NZMedDiet pattern and behaviour change support improves the cardiometabolic health of people in New Zealand.
The association between childhood maltreatment, psychopathology, and adult sexual victimization in men and women: results from three independent samples
- K. B. Werner, V. V. McCutcheon, M. Challa, A. Agrawal, M. T. Lynskey, E. Conroy, D. J. Statham, P. A. F. Madden, A. K. Henders, A. A. Todorov, A. C. Heath, L. Degenhardt, N. G. Martin, K. K. Bucholz, E. C. Nelson
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- Journal:
- Psychological Medicine / Volume 46 / Issue 3 / February 2016
- Published online by Cambridge University Press:
- 13 October 2015, pp. 563-573
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Background
Childhood maltreatment (CM) has consistently been linked with adverse outcomes including substance use disorders and adult sexual revictimization. Adult sexual victimization itself has been linked with psychopathology but has predominately been studied in women. The current investigation examines the impact of CM and co-occurring psychopathology on adult sexual victimization in men and women, replicating findings in three distinct samples.
MethodWe investigated the association between continuous CM factor scores and adult sexual victimization in the Childhood Trauma Study (CTS) sample (N = 2564). We also examined the unique relationship between childhood sexual abuse (CSA) and adult sexual victimization while adjusting for co-occurring substance dependence and psychopathology. We replicated these analyses in two additional samples: the Comorbidity and Trauma Study (CATS; N = 1981) and the Australian Twin-Family Study of Alcohol Use Disorders (OZ-ALC; N = 1537).
ResultsAnalyses revealed a significant association with CM factor scores and adult sexual victimization for both men and women across all three samples. The CSA factor score was strongly associated with adult sexual victimization after adjusting for substance dependence and psychopathology; higher odds ratios were observed in men (than women) consistently across the three samples.
ConclusionsA continuous measure of CSA is independently associated with adult sexual trauma risk across samples in models that included commonly associated substance dependence and psychopathology as covariates. The strength of the association between this CSA measure and adult sexual victimization is higher in magnitude for men than women, pointing to the need for further investigation of sexual victimization in male community samples.
Contributors
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- By J. Todd Arnedt, Sharon Aronovich, Alon Y. Avidan, Alp Sinan Baran, Johnathan Barkham, Lizabeth Binns, Tiffany J. Braley, Devin Brown, Paul R. Carney, Philip Cheng, Ronald D. Chervin, Naricha Chirakalwasan, Wattanachai Chotinaiwattarakul, Deirdre A. Conroy, Charles R. Davies, Dawn Dore-Stites, Alan S. Eiser, Todd Favorite, Barbara T. Felt, James D. Geyer, Jennifer R. Goldschmied, Cathy A. Goldstein, John J. Harrington, Fauziya Hassan, Judith L. Heidebrink, Joseph I. Helman, Shelley Hershner, Timothy F. Hoban, Edward D. Huntley, Rahul K. Kakkar, Douglas Kirsch, Raman K. Malhotra, Beth A. Malow, Lauren O’Connell, Shalini Paruthi, Meredith D. Peters, Scott M. Pickett, Satya Krishna Ramachandran, Fouad Reda, Daniel I. Rifkin, Emerson Robinson, Helena M. Schotland, Q. Afifa Shamim-Uzzaman, Anita Valanju Shelgikar, Renée A. Shellhaas, Jeffrey J. Stanley, Leslie M. Swanson, Mihai C. Teodorescu, Mihai C. Teodorescu, Sheila C. Tsai, Katherine Wilson, Michael E. Yurcheshen, Sarah Nath Zallek
- Edited by Ronald D. Chervin
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- Book:
- Common Pitfalls in Sleep Medicine
- Published online:
- 05 April 2014
- Print publication:
- 10 April 2014, pp x-xiv
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Compound viscous thread with electrostatic and electrokinetic effects
- D. T. Conroy, O. K. Matar, R. V. Craster, D. T. Papageorgiou
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- Journal:
- Journal of Fluid Mechanics / Volume 701 / 25 June 2012
- Published online by Cambridge University Press:
- 30 April 2012, pp. 171-200
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Breakup of an electrified viscous compound jet, surrounded by a dielectric gas, is investigated theoretically. The fluids are considered to be electrolytes and the core fluid viscosity is assumed to be much larger than that of the annular fluid. Axisymmetric configurations are considered with the three fluids bound by a cylindrical electrode that is held at a constant voltage potential. The model equations are investigated asymptotically in the long-wave limit, yielding two cases corresponding to a negligible surface charge with electrokinetic effects and a leaky dielectric model. A linear stability analysis for both cases is performed and the electrical effects are found to have a stabilizing effect, which is consistent with previous investigations of single electrified jet breakup at small wavenumbers. The one-dimensional equations are also solved numerically. The electric field is found to cause satellite formation in the core fluid, which does not occur in the purely hydrodynamic case, with the satellite size increasing with the strength of the electric field.
Contributors
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- By Candice A. Alfano, J. Todd Arnedt, Alon Y. Avidan, Ruth M. Benca, Jed E. Black, Katy Borodkin, Kirk J. Brower, Ritchie E. Brown, Daniel J. Buysse, Dani Choufani, Deirdre A. Conroy, Samuele Cortese, Yaron Dagan, Joel E. Dimsdale, Karl Doghramji, Fabio Ferrarelli, Marcos G. Frank, Philip R. Gehrman, Chad C. Hagen, J. Allan Hobson, Magdolna Hornyak, Thomas D. Hurwitz, Anna Ivanenko, Andrew D. Krystal, Michel Lecendreux, In-Soo Lee, Robert W. McCarley, James T. McKenna, Valerie McLaughlin Crabtree, Thomas A. Mellman, Marta Novak, Michael Perlis, Aimee L. Pierce, David T. Plante, Donn Posner, Allen C. Richert, Dieter Riemann, Carlos H. Schenck, Michael Schredl, Gregory Stores, Andras Szentkiralyi, Michael E. Thase, Wendy M. Troxel, John W. Winkelman
- Edited by John W. Winkelman, David T. Plante, University of Wisconsin, Madison
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- Book:
- Foundations of Psychiatric Sleep Medicine
- Published online:
- 01 June 2011
- Print publication:
- 23 December 2010, pp vii-x
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Dynamics and stability of an annular electrolyte film
- D. T. CONROY, R. V. CRASTER, O. K. MATAR, D. T. PAPAGEORGIOU
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- Journal:
- Journal of Fluid Mechanics / Volume 656 / 10 August 2010
- Published online by Cambridge University Press:
- 26 May 2010, pp. 481-506
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We investigate the evolution of an electrolyte film surrounding a second electrolyte core fluid inside a uniform cylindrical tube and in a core-annular arrangement, when electrostatic and electrokinetic effects are present. The limiting case when the core fluid electrolyte is a perfect conductor is examined. We analyse asymptotically the thin annulus limit to derive a nonlinear evolution equation for the interfacial position, which accounts for electrostatic and electrokinetic effects and is valid for small Debye lengths that scale with the film thickness, that is, charge separation takes place over a distance that scales with the annular layer thickness. The equation is derived and studied in the Debye-Hückel limit (valid for small potentials) as well as the fully nonlinear Poisson–Boltzmann equation. These equations are characterized by an electric capillary number, a dimensionless scaled inverse Debye length and a ratio of interface to wall electrostatic potentials. We explore the effect of electrokinetics on the interfacial dynamics using a linear stability analysis and perform extensive numerical simulations of the initial value problem under periodic boundary conditions. An allied nonlinear analysis is carried out to investigate fully singular finite-time rupture events that can take place. Depending upon the parameter regime, the electrokinetics either stabilize or destabilize the film and, in the latter case, cause the film to rupture in finite time. In this case, the final film shape can have a ring- or line-like rupture; the rupture dynamics are found to be self-similar. In contrast, in the absence of electrostatic effects, the film does not rupture in finite time but instead evolves to very long-lived quasi-static structures that are interrupted by an abrupt re-distribution of these very slowly evolving drops and lobes. The present study shows that electrokinetic effects can be tuned to rupture the film in finite time and the time to rupture can be controlled by varying the system parameters. Some intriguing and novel behaviour is also discovered in the limit of large scaled inverse Debye lengths, namely stable and smooth non-uniform steady state film shapes emerge as a result of a balance between destabilizing capillary forces and stabilizing electrokinetic forces.
Evolution of a chemically reacting plume in a ventilated room
- D. T. CONROY, STEFAN G. LLEWELLYN SMITH, C. P. CAULFIELD
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- Journal:
- Journal of Fluid Mechanics / Volume 537 / 25 August 2005
- Published online by Cambridge University Press:
- 04 August 2005, pp. 221-253
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The dynamics of a second-order chemical reaction in an enclosed space driven by the mixing produced by a turbulent buoyant plume are studied theoretically, numerically and experimentally. An isolated turbulent buoyant plume source is located in an enclosure with a single external opening. Both the source and the opening are located at the bottom of the enclosure. The enclosure is filled with a fluid of a given density with a fixed initial concentration of a chemical. The source supplies a constant volume flux of fluid of different density containing a different chemical of known and constant concentration. These two chemicals undergo a second-order non-reversible reaction, leading to the creation of a third product chemical. For simplicity, we restrict attention to the situation where the reaction process does not affect the density of the fluids involved. Because of the natural constraint of volume conservation, fluid from the enclosure is continually vented. We study the evolution of the various chemical species as they are advected by the developing ventilated filling box process within the room that is driven by the plume dynamics. In particular, we study both the mean and vertical distributions of the chemical species as a function of time within the room. We compare the results of analogue laboratory experiments with theoretical predictions derived from reduced numerical models, and find excellent agreement. Important parameters for the behaviour of the system are associated with the source volume flux and specific momentum flux relative to the source specific buoyancy flux, the ratio of the initial concentrations of the reacting chemical input in the plume and the reacting chemical in the enclosed space, the reaction rate of the chemicals and the aspect ratio of the room. Although the behaviour of the system depends on all these parameters in a non-trivial way, in general the concentration within the room of the chemical input at the isolated source passes through three distinct phases. Initially, as the source fluid flows into the room, the mean concentration of the input chemical increases due to the inflow, with some loss due to the reaction with the chemical initially within the room. After a finite time, the layer of fluid contaminated by the inflow reaches the opening to the exterior at the base of the room. During an ensuing intermediate phase, the rate of increase in the concentration of the input chemical then drops non-trivially, due to the extra sink for the input chemical of the outflow through the opening. During this intermediate stage, the concentration of the input chemical continues to rise, but at a rate that is reduced due to the reaction with the fluid in the room. Ultimately, all the fluid (and hence the chemical) that was originally within the room is lost, both through reaction and outflow through the opening, and the room approaches its final steady state, being filled completely with source fluid.