14 results
Canadian Stroke Best Practice Recommendations: Secondary Prevention of Stroke Update 2020 – ADDENDUM
- David J. Gladstone, M. Patrice Lindsay, James Douketis, Eric E. Smith, Dar Dowlatshahi, Theodore Wein, Aline Bourgoin, Jafna Cox, John B. Falconer, Brett R. Graham, Marilyn Labrie, Lena McDonald, Jennifer Mandzia, Daniel Ngui, Paul Pageau, Amanda Rodgerson, William Semchuk, Tammy Tebbutt, Carmen Tuchak, Stephen van Gaal, Karina Villaluna, Norine Foley, Shelagh Coutts, Anita Mountain, Gord Gubitz, Jacob A Udell, Rebecca McGuff, Manraj K.S. Heran, Pascale Lavoie, Alexandre Y. Poppe
-
- Journal:
- Canadian Journal of Neurological Sciences / Volume 50 / Issue 3 / May 2023
- Published online by Cambridge University Press:
- 03 June 2022, p. 481
-
- Article
-
- You have access Access
- Open access
- HTML
- Export citation
Canadian Stroke Best Practice Recommendations: Secondary Prevention of Stroke Update 2020
- David J. Gladstone, M. Patrice Lindsay, James Douketis, Eric E. Smith, Dar Dowlatshahi, Theodore Wein, Aline Bourgoin, Jafna Cox, John B. Falconer, Brett R. Graham, Marilyn Labrie, Lena McDonald, Jennifer Mandzia, Daniel Ngui, Paul Pageau, Amanda Rodgerson, William Semchuk, Tammy Tebbutt, Carmen Tuchak, Stephen van Gaal, Karina Villaluna, Norine Foley, Shelagh Coutts, Anita Mountain, Gord Gubitz, Jacob A Udell, Rebecca McGuff, Manraj K.S. Heran, Pascale Lavoie, Alexandre Y. Poppe, , the Canadian Stroke Consortium
-
- Journal:
- Canadian Journal of Neurological Sciences / Volume 49 / Issue 3 / May 2022
- Published online by Cambridge University Press:
- 18 June 2021, pp. 315-337
-
- Article
-
- You have access Access
- Open access
- HTML
- Export citation
-
The 2020 update of the Canadian Stroke Best Practice Recommendations (CSBPR) for the Secondary Prevention of Stroke includes current evidence-based recommendations and expert opinions intended for use by clinicians across a broad range of settings. They provide guidance for the prevention of ischemic stroke recurrence through the identification and management of modifiable vascular risk factors. Recommendations address triage, diagnostic testing, lifestyle behaviors, vaping, hypertension, hyperlipidemia, diabetes, atrial fibrillation, other cardiac conditions, antiplatelet and anticoagulant therapies, and carotid and vertebral artery disease. This update of the previous 2017 guideline contains several new or revised recommendations. Recommendations regarding triage and initial assessment of acute transient ischemic attack (TIA) and minor stroke have been simplified, and selected aspects of the etiological stroke workup are revised. Updated treatment recommendations based on new evidence have been made for dual antiplatelet therapy for TIA and minor stroke; anticoagulant therapy for atrial fibrillation; embolic strokes of undetermined source; low-density lipoprotein lowering; hypertriglyceridemia; diabetes treatment; and patent foramen ovale management. A new section has been added to provide practical guidance regarding temporary interruption of antithrombotic therapy for surgical procedures. Cancer-associated ischemic stroke is addressed. A section on virtual care delivery of secondary stroke prevention services in included to highlight a shifting paradigm of care delivery made more urgent by the global pandemic. In addition, where appropriate, sex differences as they pertain to treatments have been addressed. The CSBPR include supporting materials such as implementation resources to facilitate the adoption of evidence into practice and performance measures to enable monitoring of uptake and effectiveness of recommendations.
Using energy requirements to compare the suitability of alternative methods for broadcast and site-specific weed control – CORRIGENDUM
- Guy R. Y. Coleman, Amanda Stead, Marc P. Rigter, Zhe Xu, David Johnson, Graham M. Brooker, Salah Sukkarieh, Michael J. Walsh
-
- Journal:
- Weed Technology / Volume 34 / Issue 1 / February 2020
- Published online by Cambridge University Press:
- 13 January 2020, pp. 153-154
-
- Article
-
- You have access Access
- Open access
- HTML
- Export citation
Using energy requirements to compare the suitability of alternative methods for broadcast and site-specific weed control
- Guy R. Y. Coleman, Amanda Stead, Marc P. Rigter, Zhe Xu, David Johnson, Graham M. Brooker, Salah Sukkarieh, Michael J. Walsh
-
- Journal:
- Weed Technology / Volume 33 / Issue 4 / August 2019
- Published online by Cambridge University Press:
- 29 May 2019, pp. 633-650
-
- Article
-
- You have access Access
- Open access
- HTML
- Export citation
-
The widespread use of herbicides in cropping systems has led to the evolution of resistance in major weeds. The resultant loss of herbicide efficacy is compounded by a lack of new herbicide sites of action, driving demand for alternative weed control technologies. While there are many alternative methods for control, identifying the most appropriate method to pursue for commercial development has been hampered by the inability to compare techniques in a fair and equitable manner. Given that all currently available and alternative weed control methods share an intrinsic energy consumption, the aim of this review was to compare methods based on energy consumption. Energy consumption was compared for chemical, mechanical, and thermal weed control technologies when applied as broadcast (whole-field) and site-specific treatments. Tillage systems, such as flex-tine harrow (4.2 to 5.5 MJ ha−1), sweep cultivator (13 to 14 MJ ha−1), and rotary hoe (12 to 17 MJ ha−1) consumed the least energy of broadcast weed control treatments. Thermal-based approaches, including flaming (1,008 to 4,334 MJ ha−1) and infrared (2,000 to 3,887 MJ ha−1), are more appropriate for use in conservation cropping systems; however, their energy requirements are 100- to 1,000-fold greater than those of tillage treatments. The site-specific application of weed control treatments to control 2-leaf-stage broadleaf weeds at a density of 5 plants m−2 reduced energy consumption of herbicidal, thermal, and mechanical treatments by 97%, 99%, and 97%, respectively. Significantly, this site-specific approach resulted in similar energy requirements for current and alternative technologies (e.g., electrocution [15 to 19 MJ ha−1], laser pyrolysis [15 to 249 MJ ha−1], hoeing [17 MJ ha−1], and herbicides [15 MJ ha−1]). Using similar energy sources, a standardized energy comparison provides an opportunity for estimation of weed control costs, suggesting site-specific weed management is critical in the economically realistic implementation of alternative technologies.
Helicobacter pylori as an oncogenic pathogen, revisited
- Muhammad Miftahussurur, Yoshio Yamaoka, David Y. Graham
-
- Journal:
- Expert Reviews in Molecular Medicine / Volume 19 / 2017
- Published online by Cambridge University Press:
- 21 March 2017, e4
-
- Article
- Export citation
-
Gastric cancer is an inflammation-associated malignancy aetiologically related to infection with the bacterium, Helicobacter pylori, which is considered a necessary but insufficient cause. Unless treated, H. pylori causes life-long acute and chronic gastric inflammation resulting in progressive gastric mucosal damage that may result in gastric cancer. The rate of progression from superficial gastritis, to an atrophic metaplastic mucosa, and ultimately to cancer relates to the virulence of the infecting H. pylori as well as host and environmental factors. H. pylori virulence is a reflection of its propensity to cause severe gastric inflammation. Both mucosal inflammation and H. pylori can cause host genomic instability, including dysregulation of DNA mismatch repair, stimulation of expression of activation-induced cytidine deaminase, abnormal DNA methylation and dysregulation of micro RNAs, which may result in an accumulation of mutations and loss of normal regulation of cell growth. The difference in cancer risk between the most and least virulent H. pylori strain is only approximately 2-fold. Overall, none of the putative virulence factors identified to date have proved to be disease-specific. The presence, severity, extent and duration of inflammation appear to be the most important factors and current evidence suggests that any host, environmental or bacterial factor that reliably enhances the inflammatory response to the H. pylori infection increases the risk of gastric cancer.
Contributors
-
- By Mitchell Aboulafia, Frederick Adams, Marilyn McCord Adams, Robert M. Adams, Laird Addis, James W. Allard, David Allison, William P. Alston, Karl Ameriks, C. Anthony Anderson, David Leech Anderson, Lanier Anderson, Roger Ariew, David Armstrong, Denis G. Arnold, E. J. Ashworth, Margaret Atherton, Robin Attfield, Bruce Aune, Edward Wilson Averill, Jody Azzouni, Kent Bach, Andrew Bailey, Lynne Rudder Baker, Thomas R. Baldwin, Jon Barwise, George Bealer, William Bechtel, Lawrence C. Becker, Mark A. Bedau, Ernst Behler, José A. Benardete, Ermanno Bencivenga, Jan Berg, Michael Bergmann, Robert L. Bernasconi, Sven Bernecker, Bernard Berofsky, Rod Bertolet, Charles J. Beyer, Christian Beyer, Joseph Bien, Joseph Bien, Peg Birmingham, Ivan Boh, James Bohman, Daniel Bonevac, Laurence BonJour, William J. Bouwsma, Raymond D. Bradley, Myles Brand, Richard B. Brandt, Michael E. Bratman, Stephen E. Braude, Daniel Breazeale, Angela Breitenbach, Jason Bridges, David O. Brink, Gordon G. Brittan, Justin Broackes, Dan W. Brock, Aaron Bronfman, Jeffrey E. Brower, Bartosz Brozek, Anthony Brueckner, Jeffrey Bub, Lara Buchak, Otavio Bueno, Ann E. Bumpus, Robert W. Burch, John Burgess, Arthur W. Burks, Panayot Butchvarov, Robert E. Butts, Marina Bykova, Patrick Byrne, David Carr, Noël Carroll, Edward S. Casey, Victor Caston, Victor Caston, Albert Casullo, Robert L. Causey, Alan K. L. Chan, Ruth Chang, Deen K. Chatterjee, Andrew Chignell, Roderick M. Chisholm, Kelly J. Clark, E. J. Coffman, Robin Collins, Brian P. Copenhaver, John Corcoran, John Cottingham, Roger Crisp, Frederick J. Crosson, Antonio S. Cua, Phillip D. Cummins, Martin Curd, Adam Cureton, Andrew Cutrofello, Stephen Darwall, Paul Sheldon Davies, Wayne A. Davis, Timothy Joseph Day, Claudio de Almeida, Mario De Caro, Mario De Caro, John Deigh, C. F. Delaney, Daniel C. Dennett, Michael R. DePaul, Michael Detlefsen, Daniel Trent Devereux, Philip E. Devine, John M. Dillon, Martin C. Dillon, Robert DiSalle, Mary Domski, Alan Donagan, Paul Draper, Fred Dretske, Mircea Dumitru, Wilhelm Dupré, Gerald Dworkin, John Earman, Ellery Eells, Catherine Z. Elgin, Berent Enç, Ronald P. Endicott, Edward Erwin, John Etchemendy, C. Stephen Evans, Susan L. Feagin, Solomon Feferman, Richard Feldman, Arthur Fine, Maurice A. Finocchiaro, William FitzPatrick, Richard E. Flathman, Gvozden Flego, Richard Foley, Graeme Forbes, Rainer Forst, Malcolm R. Forster, Daniel Fouke, Patrick Francken, Samuel Freeman, Elizabeth Fricker, Miranda Fricker, Michael Friedman, Michael Fuerstein, Richard A. Fumerton, Alan Gabbey, Pieranna Garavaso, Daniel Garber, Jorge L. A. Garcia, Robert K. Garcia, Don Garrett, Philip Gasper, Gerald Gaus, Berys Gaut, Bernard Gert, Roger F. Gibson, Cody Gilmore, Carl Ginet, Alan H. Goldman, Alvin I. Goldman, Alfonso Gömez-Lobo, Lenn E. Goodman, Robert M. Gordon, Stefan Gosepath, Jorge J. E. Gracia, Daniel W. Graham, George A. Graham, Peter J. Graham, Richard E. Grandy, I. Grattan-Guinness, John Greco, Philip T. Grier, Nicholas Griffin, Nicholas Griffin, David A. Griffiths, Paul J. Griffiths, Stephen R. Grimm, Charles L. Griswold, Charles B. Guignon, Pete A. Y. Gunter, Dimitri Gutas, Gary Gutting, Paul Guyer, Kwame Gyekye, Oscar A. Haac, Raul Hakli, Raul Hakli, Michael Hallett, Edward C. Halper, Jean Hampton, R. James Hankinson, K. R. Hanley, Russell Hardin, Robert M. Harnish, William Harper, David Harrah, Kevin Hart, Ali Hasan, William Hasker, John Haugeland, Roger Hausheer, William Heald, Peter Heath, Richard Heck, John F. Heil, Vincent F. Hendricks, Stephen Hetherington, Francis Heylighen, Kathleen Marie Higgins, Risto Hilpinen, Harold T. Hodes, Joshua Hoffman, Alan Holland, Robert L. Holmes, Richard Holton, Brad W. Hooker, Terence E. Horgan, Tamara Horowitz, Paul Horwich, Vittorio Hösle, Paul Hoβfeld, Daniel Howard-Snyder, Frances Howard-Snyder, Anne Hudson, Deal W. Hudson, Carl A. Huffman, David L. Hull, Patricia Huntington, Thomas Hurka, Paul Hurley, Rosalind Hursthouse, Guillermo Hurtado, Ronald E. Hustwit, Sarah Hutton, Jonathan Jenkins Ichikawa, Harry A. Ide, David Ingram, Philip J. Ivanhoe, Alfred L. Ivry, Frank Jackson, Dale Jacquette, Joseph Jedwab, Richard Jeffrey, David Alan Johnson, Edward Johnson, Mark D. Jordan, Richard Joyce, Hwa Yol Jung, Robert Hillary Kane, Tomis Kapitan, Jacquelyn Ann K. Kegley, James A. Keller, Ralph Kennedy, Sergei Khoruzhii, Jaegwon Kim, Yersu Kim, Nathan L. King, Patricia Kitcher, Peter D. Klein, E. D. Klemke, Virginia Klenk, George L. Kline, Christian Klotz, Simo Knuuttila, Joseph J. Kockelmans, Konstantin Kolenda, Sebastian Tomasz Kołodziejczyk, Isaac Kramnick, Richard Kraut, Fred Kroon, Manfred Kuehn, Steven T. Kuhn, Henry E. Kyburg, John Lachs, Jennifer Lackey, Stephen E. Lahey, Andrea Lavazza, Thomas H. Leahey, Joo Heung Lee, Keith Lehrer, Dorothy Leland, Noah M. Lemos, Ernest LePore, Sarah-Jane Leslie, Isaac Levi, Andrew Levine, Alan E. Lewis, Daniel E. Little, Shu-hsien Liu, Shu-hsien Liu, Alan K. L. Chan, Brian Loar, Lawrence B. Lombard, John Longeway, Dominic McIver Lopes, Michael J. Loux, E. J. Lowe, Steven Luper, Eugene C. Luschei, William G. Lycan, David Lyons, David Macarthur, Danielle Macbeth, Scott MacDonald, Jacob L. Mackey, Louis H. Mackey, Penelope Mackie, Edward H. Madden, Penelope Maddy, G. B. Madison, Bernd Magnus, Pekka Mäkelä, Rudolf A. Makkreel, David Manley, William E. Mann (W.E.M.), Vladimir Marchenkov, Peter Markie, Jean-Pierre Marquis, Ausonio Marras, Mike W. Martin, A. P. Martinich, William L. McBride, David McCabe, Storrs McCall, Hugh J. McCann, Robert N. McCauley, John J. McDermott, Sarah McGrath, Ralph McInerny, Daniel J. McKaughan, Thomas McKay, Michael McKinsey, Brian P. McLaughlin, Ernan McMullin, Anthonie Meijers, Jack W. Meiland, William Jason Melanson, Alfred R. Mele, Joseph R. Mendola, Christopher Menzel, Michael J. Meyer, Christian B. Miller, David W. Miller, Peter Millican, Robert N. Minor, Phillip Mitsis, James A. Montmarquet, Michael S. Moore, Tim Moore, Benjamin Morison, Donald R. Morrison, Stephen J. Morse, Paul K. Moser, Alexander P. D. Mourelatos, Ian Mueller, James Bernard Murphy, Mark C. Murphy, Steven Nadler, Jan Narveson, Alan Nelson, Jerome Neu, Samuel Newlands, Kai Nielsen, Ilkka Niiniluoto, Carlos G. Noreña, Calvin G. Normore, David Fate Norton, Nikolaj Nottelmann, Donald Nute, David S. Oderberg, Steve Odin, Michael O’Rourke, Willard G. Oxtoby, Heinz Paetzold, George S. Pappas, Anthony J. Parel, Lydia Patton, R. P. Peerenboom, Francis Jeffry Pelletier, Adriaan T. Peperzak, Derk Pereboom, Jaroslav Peregrin, Glen Pettigrove, Philip Pettit, Edmund L. Pincoffs, Andrew Pinsent, Robert B. Pippin, Alvin Plantinga, Louis P. Pojman, Richard H. Popkin, John F. Post, Carl J. Posy, William J. Prior, Richard Purtill, Michael Quante, Philip L. Quinn, Philip L. Quinn, Elizabeth S. Radcliffe, Diana Raffman, Gerard Raulet, Stephen L. Read, Andrews Reath, Andrew Reisner, Nicholas Rescher, Henry S. Richardson, Robert C. Richardson, Thomas Ricketts, Wayne D. Riggs, Mark Roberts, Robert C. Roberts, Luke Robinson, Alexander Rosenberg, Gary Rosenkranz, Bernice Glatzer Rosenthal, Adina L. Roskies, William L. Rowe, T. M. Rudavsky, Michael Ruse, Bruce Russell, Lilly-Marlene Russow, Dan Ryder, R. M. Sainsbury, Joseph Salerno, Nathan Salmon, Wesley C. Salmon, Constantine Sandis, David H. Sanford, Marco Santambrogio, David Sapire, Ruth A. Saunders, Geoffrey Sayre-McCord, Charles Sayward, James P. Scanlan, Richard Schacht, Tamar Schapiro, Frederick F. Schmitt, Jerome B. Schneewind, Calvin O. Schrag, Alan D. Schrift, George F. Schumm, Jean-Loup Seban, David N. Sedley, Kenneth Seeskin, Krister Segerberg, Charlene Haddock Seigfried, Dennis M. Senchuk, James F. Sennett, William Lad Sessions, Stewart Shapiro, Tommie Shelby, Donald W. Sherburne, Christopher Shields, Roger A. Shiner, Sydney Shoemaker, Robert K. Shope, Kwong-loi Shun, Wilfried Sieg, A. John Simmons, Robert L. Simon, Marcus G. Singer, Georgette Sinkler, Walter Sinnott-Armstrong, Matti T. Sintonen, Lawrence Sklar, Brian Skyrms, Robert C. Sleigh, Michael Anthony Slote, Hans Sluga, Barry Smith, Michael Smith, Robin Smith, Robert Sokolowski, Robert C. Solomon, Marta Soniewicka, Philip Soper, Ernest Sosa, Nicholas Southwood, Paul Vincent Spade, T. L. S. Sprigge, Eric O. Springsted, George J. Stack, Rebecca Stangl, Jason Stanley, Florian Steinberger, Sören Stenlund, Christopher Stephens, James P. Sterba, Josef Stern, Matthias Steup, M. A. Stewart, Leopold Stubenberg, Edith Dudley Sulla, Frederick Suppe, Jere Paul Surber, David George Sussman, Sigrún Svavarsdóttir, Zeno G. Swijtink, Richard Swinburne, Charles C. Taliaferro, Robert B. Talisse, John Tasioulas, Paul Teller, Larry S. Temkin, Mark Textor, H. S. Thayer, Peter Thielke, Alan Thomas, Amie L. Thomasson, Katherine Thomson-Jones, Joshua C. Thurow, Vzalerie Tiberius, Terrence N. Tice, Paul Tidman, Mark C. Timmons, William Tolhurst, James E. Tomberlin, Rosemarie Tong, Lawrence Torcello, Kelly Trogdon, J. D. Trout, Robert E. Tully, Raimo Tuomela, John Turri, Martin M. Tweedale, Thomas Uebel, Jennifer Uleman, James Van Cleve, Harry van der Linden, Peter van Inwagen, Bryan W. Van Norden, René van Woudenberg, Donald Phillip Verene, Samantha Vice, Thomas Vinci, Donald Wayne Viney, Barbara Von Eckardt, Peter B. M. Vranas, Steven J. Wagner, William J. Wainwright, Paul E. Walker, Robert E. Wall, Craig Walton, Douglas Walton, Eric Watkins, Richard A. Watson, Michael V. Wedin, Rudolph H. Weingartner, Paul Weirich, Paul J. Weithman, Carl Wellman, Howard Wettstein, Samuel C. Wheeler, Stephen A. White, Jennifer Whiting, Edward R. Wierenga, Michael Williams, Fred Wilson, W. Kent Wilson, Kenneth P. Winkler, John F. Wippel, Jan Woleński, Allan B. Wolter, Nicholas P. Wolterstorff, Rega Wood, W. Jay Wood, Paul Woodruff, Alison Wylie, Gideon Yaffe, Takashi Yagisawa, Yutaka Yamamoto, Keith E. Yandell, Xiaomei Yang, Dean Zimmerman, Günter Zoller, Catherine Zuckert, Michael Zuckert, Jack A. Zupko (J.A.Z.)
- Edited by Robert Audi, University of Notre Dame, Indiana
-
- Book:
- The Cambridge Dictionary of Philosophy
- Published online:
- 05 August 2015
- Print publication:
- 27 April 2015, pp ix-xxx
-
- Chapter
- Export citation
138 - Helicobacter pylori
- from Part XVIII - Specific organisms: bacteria
-
- By David Y. Graham, Baylor College of Medicine, Emiko Rimbara, National Institute of Infectious Diseases
- Edited by David Schlossberg, Temple University, Philadelphia
-
- Book:
- Clinical Infectious Disease
- Published online:
- 05 April 2015
- Print publication:
- 23 April 2015, pp 907-914
-
- Chapter
- Export citation
-
Summary
Introduction
Helicobacter pylori are gram-negative spiral shaped-bacteria that infect more than 50% of humans globally. H. pylori infection is a serious chronic transmissible infectious disease that causes inflammation and progressive damage to the structure and function of the stomach. H. pylori is a major cause of morbidity and mortality worldwide. The prevalence of H. pylori infection is inversely related to the general health and well-being of a society. As with other chronic infectious diseases, the infection remains clinically latent and only approximately 20% of infected individuals eventually develop clinically recognizable diseases. H. pylori infection causes progressive and destructive inflammation (e.g., gastritis) of the stomach and is the infection etiologically related to gastric and duodenal ulcer disease, gastric cancer, and primary B-cell gastric lymphoma.
Discovery of H. pylori
In the early 1980s, Robin Warren, a pathologist in Perth, Western Australia teamed up with a young trainee in internal medicine, Barry Marshall, to investigate small curved bacteria seen on gastric biopsies from patients with gastritis. In 1982, with a bit of luck, the organism was cultured and initially named Campylobacter pyloridis. It is now known as Helicobacter pylori and is a microaerophilic, gram-negative, spiral rod approximately 0.6 × 3.5 µm with approximately seven unipolar flagellae. Biochemical features that help identify it are the presence of urease, oxidase, and catalase.
Contributors
-
- By Denis Barabé, Craig F. Barrett, Josef Bogner, Mark W. Chase, James I. Cohen, Natalie Cusimano, Jerrold I. Davis, Melvin R. Duvall, Carol A. Furness, Thomas J. Givnish, Rafaël Govaerts, Sean W. Graham, William J. D. Iles, F. Andrew Jones, Jim Leebens-Mack, Donald H. Les, Simon J. Mayo, Joel R. McNeal, Renato Mello-Silva, Jin Murata, C. David, L. Orme, Gitte Petersen, J. Chris Pires, Margarita V. Remizowa, Paula J. Rudall, Maria das Graças Sajo, Vincent Savolainen, Robert W. Scotland, Ole Seberg, Selena Y. Smith, Benjamin Sobkowiak, Dmitry D. Sokoloff, Dennis W. Stevenson, Norio Tanaka, Nicholas P. Tippery, Koichi Uehara, Paul Wilkin
- Edited by Paul Wilkin, Royal Botanic Gardens, Kew, Simon J. Mayo, Royal Botanic Gardens, Kew
-
- Book:
- Early Events in Monocot Evolution
- Published online:
- 05 June 2013
- Print publication:
- 30 May 2013, pp -
-
- Chapter
- Export citation
Contributors
-
- By Jennifer L. Allen, Inés Baños, Isabel Boege, Susan M. Bögels, Sam Cartwright-Hatton, Sarah Clark, Judith A. Cohen, Cathy Creswell, Esther I. de Bruin, Jessica Deighton, Helen F. Dodd, Caroline L. Donovan, Nicola Dummett, Sandra Dunsmuir, Melinda Edwards, Lara J. Farrell, Iyabo A. Fatimilehin, Andrew Fugard, Peter Fuggle, Philip Graham, Alice M. Gregory, Amira Hassan, Kevin Hilbert, Jennifer L. Hudson, Georgina C. Krebs, Jennifer Y. F. Lau, Anthony P. Mannarino, Sonja March, Ella L. Milliner, Laura K. Murray, Lynne Murray, Carol Newall, Thomas H. Ollendick, Dennis Ougrin, Ronald M. Rapee, Shirley Reynolds, Natalie Rodriguez, Benjamin C. Schwartzman, Stephen Scott, Susan H. Spence, Paul Stallard, Ellen Trautmann, David Trickey, Cynthia M. Turner, Saskia van der Oord, Beth Watkins, Miranda Wolpert, Jeffrey J. Wood
- Edited by Philip Graham, Shirley Reynolds, University of Reading
-
- Book:
- Cognitive Behaviour Therapy for Children and Families
- Published online:
- 05 March 2013
- Print publication:
- 14 March 2013, pp viii-x
-
- Chapter
- Export citation
Contributors
-
- By Emily Abbey, Charl Alberts, Herman Baert, Shalini Bahl, John Barresi, Marie-Cécile Bertau, Sunil Bhatia, Kenneth R. Cabell, Nandita Chaudhary, Elżbieta Chmielnicka-Kuter, Giancarlo Dimaggio, Shaun Gallagher, Thorsten Gieser, Alex Gillespie, Miguel M. Gonçalves, Hubert J. M. Hermans, Agnieszka Hermans-Konopka, Vincent W. Hevern, David Y. F. Ho, Carol A. Jasper, Dorota Kobylińska, Reinekke Lengelle, M. Beatrice Ligorio, Graham Lindegger, John T. Lysaker, Paul H. Lysaker, Frans Meijers, Toon van Meijl, Helen R. Moore, Masayoshi Morioka, Robert A. Neimeyer, Dina Nir, Piotr K. Oleś, Małgorzata Puchalska-Wasyl, Peter T. F. Raggatt, António P. Ribeiro, John Rowan, Katarzyna Stemplewska-Żakowicz, Seth Surgan, Hubert Suszek, Jaan Valsiner, Leni M. F. Verhofstadt-Denève, Lisa S. Whittaker, Annemie Winters, Bartosz Zalewski, Renata Żurawska-Żyła
- Edited by Hubert J. M. Hermans, Radboud Universiteit Nijmegen, Thorsten Gieser, Universität Koblenz-Landau, Germany
-
- Book:
- Handbook of Dialogical Self Theory
- Published online:
- 05 June 2012
- Print publication:
- 24 November 2011, pp x-xiii
-
- Chapter
- Export citation
List of Contributors
-
- By Harold P. Adams, Colum F. Amory, Anne Angelillo-Scherrer, Irena Anselm, Marcel Arnold, Robert W. Baloh, Ralf W. Baumgartner, José Biller, Valérie Biousse, Matthias Bischof, Julien Bogousslavsky, Natan M. Bornstein, Marie Germaine Bousser, Robin L. Brey, John C. M. Brust, Alan Bryer, Olivier Calvetti, Louis R. Caplan, José Castillo, Hugues Chabriat, Chin-Sang Chung, Charlotte Cordonnier, Steven C. Cramer, Luís Cunha, Rima M. Dafer, John F. Dashe, Cyrus K. Dastur, Antonio Dávalos, Larry E. Davis, Patricia Davis, Stephen M. Davis, Jan L. De Bleecker, Michael A. De Georgia, Amir R. Dehdashti, Oscar H. Del Brutto, Jacques L. De Reuck, Hans-Christoph Diener, Kathleen B. Digre, Vivian U. Fritz, Nancy Futrell, Bhuwan P. Garg, Philip B. Gorelick, Glenn D. Graham, Alexander Y. Gur, John J. Halperin, Michael Hennerici, Isabel Lestro Henriques, Roberto C. Heros, Daniel B. Hier, Lorenz Hirt, Joanna C. Jen, Taro Kaibara, Sumit Kapoor, Sarosh M. Katrak, Siddharth Kharkar, Walter J. Koroshetz, Monisha Kumar, Sandeep Kumar, Emre Kumral, Tobias Kurth, Rogelio Leira, Steven R. Levine, Didier Leys, Doris Lin, Jonathan Lipton, Alfredo M. Lopez-Yunez, Betsy B. Love, Ayrton Roberto Massaro, Heinrich P. Mattle, Manu Mehdiratta, John H. Menkes, Philippe Metellus, Reto Meuli, Patrik Michel, Panayiotis Mitsias, Jorge Moncayo-Gaete, Julien Morier, Krassen Nedeltchev, Bernhard Neundörfer, Olukemi A. Olugemo, Nikolaos I. H. Papamitsakis, Stephen D. Reck, Luca Regli, Marc D. Reichhart, Daniele Rigamonti, Michael J. Rivkin, E. Steve Roach, Jose F. Roldan, David Z. Rose, Daniel M. Rosenbaum, N. Paul Rosman, Elayna O. Rubens, Sean I. Savitz, Marc Schapira, Robert J. Schwartzman, Magdy Selim, Yukito Shinohara, Aneesh B. Singhal, Michael A. Sloan, Barney J. Stern, Mathias Sturzenegger, Oriana Thompson, A. Wesley Thevathasan, Jonathan D. Trobe, Michael Varner, Dana Védy, Jorge Vidaurre, Engin Y. Yilmaz, Khaled Zamel, Mathieu Zuber
- Edited by Louis R. Caplan, Julien Bogousslavsky
-
- Book:
- Uncommon Causes of Stroke
- Published online:
- 06 January 2010
- Print publication:
- 09 October 2008, pp ix-xiv
-
- Chapter
- Export citation
136 - Helicobacter Pylori
- from Part XVIII - Specific Organisms – Bacteria
-
- By Ping-I Hsu, National Yang-Ming University, David Y. Graham, Baylor College of Medicine
- Edited by David Schlossberg
-
- Book:
- Clinical Infectious Disease
- Published online:
- 05 March 2013
- Print publication:
- 12 May 2008, pp 969-976
-
- Chapter
- Export citation
-
Summary
INTRODUCTION
Helicobacter pylori are gram-negative spiral shaped bacteria that infect more than 50% of humans globally. Helicobacter pylori infection is a serious chronic transmissible infectious disease that causes damage to gastric structure and function and is a major cause of morbidity and mortality worldwide. The prevalence of H. pylori is inversely related to the general health and well-being of a society. However, as with other chronic infectious diseases, the infection remains clinically latent in most with about 20% of infected individuals developing clinically recognizable diseases. The natural niche for the organism is the human stomach, where it causes destructive inflammation (eg, gastritis). Helicobacter pylori is now accepted as the major cause of gastric and duodenal ulcer disease, gastric cancer, and primary B-cell gastric lymphoma. It is also responsible for some cases of nonulcer dyspepsia.
DISCOVERY OF H. PYLORI
In the early 1980s, Robin Warren, a pathologist in Perth, Western Australia, who had observed small curved bacteria in gastric biopsy specimens, teamed up with a young trainee in internal medicine, Barry Marshall, to further investigate the role of these bacteria in human disease. By 1982, with a bit of luck, Marshall successfully isolated the organism from biopsy specimens. The organism was initially named Campylobacter pyloridis based on the insight from Warren that the organism looked like a Campylobacter. That organism is now known as H. pylori and is a microaerophilic, gram-negative, spiral rod approximately 0.6 × 3.5 μ with approximately 7 unipolar flagellae.
Contributors
-
- By Graham Allan, Donna M. Allen, Irwin Altman, Arthur Aron, Donald H. Baucom, Steven R. H. Beach, Ellen Berscheid, Rosemary Blieszner, Jeffrey Boase, Tyfany M. J. Boettcher, Barbara B. Brown, Abraham P. Buunk, Lorne Campbell, Daniel J. Canary, Rodney Cate, John P. Caughlin, Mahnaz Charania, Jennie Y. Chen, F. Scott Christopher, Jennifer A. Clarke, Marilyn Coleman, W. Andrew Collins, Michael K. Coolsen, Nathan R. Cottle, Carolyn E. Cutrona, Marianne Dainton, Valerian J. Derlega, Lisa M. Diamond, Pieternel Dijkstra, Steve Duck, Pearl A. Dykstra, Norman B. Epstein, Beverley Fehr, Frank D. Fincham, Helen E. Fisher, Julie Fitness, Garth J. O. Fletcher, Myron D. Friesen, Lawrence Ganong, Kelli A. Gardner, Jenny de Jong Gierveld, Robin Goodwin, Christine R. Gray, Kathryn Greene, David W. Harris, Willard W. Hartup, John H. Harvey, Kathi L. Heffner, Ted L. Huston, William J. Ickes, Emily A. Impett, Michael P. Johnson, Deborah J. Jones, Deborah A. Kashy, Janice K. Kiecolt‐Glaser, Jeffrey L. Kirchner, Brighid M. Kleinman, Galena H. Kline, Mark L. Knapp, Ascan Koerner, Jean‐Philippe Laurenceau, Kim Leon, Timothy J. Loving, Stephanie D. Madsen, Howard J. Markman, Alicia Mathews, Mario Mikulincer, Patricia Noller, Nickola C. Overall, Letitia Anne Peplau, Daniel Perlman, Sally Planalp, Urmila Pillay, Nicole D. Pleasant, Caryl E. Rusbult, Barbara R. Sarason, Irwin G. Sarason, Phillip R. Shaver, Alan L. Sillars, Jeffry A. Simpson, Susan Sprecher, Susan Stanton, Greg Strong, Catherine A. Surra, Anita L. Vangelisti, C. Arthur VanLear, Theo van Tilburg, Barry Wellman, Amy Wenzel, Carol M. Werner, Adam R. West, Sarah W. Whitton, Heike A. Winterheld
- Edited by Anita L. Vangelisti, University of Texas, Austin, Daniel Perlman, University of British Columbia, Vancouver
-
- Book:
- The Cambridge Handbook of Personal Relationships
- Published online:
- 05 June 2012
- Print publication:
- 05 June 2006, pp xvii-xxii
-
- Chapter
- Export citation
Percutaneous Feeding Tube Changes in Long-Term–Care Facility Patients
- Sylvia Graham, Gloria Sim, Ruby Laughren, Joyce Chicoine, Edith Stephenson, Gwen Leche, Margaret McIntyre, David Murray, Fred Y. Aoki, Lindsay E. Nicolle
-
- Journal:
- Infection Control & Hospital Epidemiology / Volume 17 / Issue 11 / November 1996
- Published online by Cambridge University Press:
- 02 January 2015, pp. 732-736
- Print publication:
- November 1996
-
- Article
- Export citation
-
Objective:
To compare patient outcomes when percutaneous feeding tubes were changed routinely each month or only when necessary (prn).
Design:Prospective, randomized, nonblinded crossover study of 6 months of routine monthly changes compared with 6 months of prn changes.
Setting:416-bed long-term–care facility.
Patients:26 permanent residents with nutrition managed through percutaneous gastrostomy or jejunosto-my feeding tubes. The median age was 61.5 years; 8 (31%) also had tracheostomies, and 3 (12%) had indwelling urinary catheters.
Results:The frequency of feeding tube changes was 40 per 1,000 patient-days during the 6 months of routine tube changes and 14 per 1,000 when tubes were changed prn (P<.001). There were no differences between the two study periods in frequency of stoma site infections, fever, episodes of emesis, and total antibiotic courses. The median duration in situ of feeding tubes with prn changes was 104 days. For both periods, feeding tubes were significantly more likely to fall out and require replacement within 24 hours of previous tube replacement.
Conclusion:There were no observed differences in clinical outcomes in long-term–care facility patients when feeding tubes were changed only as necessary as compared to routine monthly changes.