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Secondary flows in turbulent boundary layers developing over truncated cone surfaces
- Ioannis K. Kaminaris, Elias Balaras, Michael P. Schultz, Ralph J. Volino
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- Journal:
- Journal of Fluid Mechanics / Volume 961 / 25 April 2023
- Published online by Cambridge University Press:
- 24 April 2023, A23
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The evolution of a turbulent boundary layer over truncated cones in staggered and random configurations is investigated using direct numerical simulations. Three random planform densities and one staggered, which closely match the configuration in the recent experiment by Womack et al. (J. Fluid Mech., vol. 933, 2022, A38), are considered. The experiment is also used to validate the present computations which are found to reproduce the flow measurements very accurately. Spanwise heterogeneity in the mean streamwise velocity in the form of high and low momentum pathways was detected in both the staggered and random arrangements, indicating the presence of secondary flows in the cross-stream plane. The momentum pathways found in the staggered arrangements are much weaker and confined near the roughness crest, while in the random arrangements they approach the edge of the boundary layer. We found a clear correlation of the momentum pathways with the leading edge of the roughness, while the correlation to the local topography was very weak for all the cases studied. Vorticity transport analysis is also employed to explore the nature of the secondary flows formed, highlighting the strong presence of vortex stretching near the leading edge of the roughness. The impact of the momentum pathways on the flow statistics, especially in the random arrangements, is demonstrated by the breakdown of outer-layer similarity.
Comparison of smooth- and rough-wall non-equilibrium boundary layers with favourable and adverse pressure gradients
- Ralph J. Volino, Michael P. Schultz
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- Journal:
- Journal of Fluid Mechanics / Volume 959 / 25 March 2023
- Published online by Cambridge University Press:
- 23 March 2023, A35
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Measurements were made in rough-wall boundary layers subject to favourable, zero and adverse pressure gradients. Profiles of mean velocity and turbulence quantities were acquired and velocity fields were measured in multiple planes to document flow structure. Comparisons were made to equivalent smooth-wall cases with the same free stream velocity distributions. Outer layer similarity was observed between the rough- and smooth-wall cases in all quantities in the favourable and zero pressure gradient regions, but large differences were observed with adverse pressure gradients. In both the smooth- and rough-wall cases, the favourable pressure gradient reduced the turbulence in the boundary layer, and increased the size of turbulence structures relative to the boundary layer thickness in both the streamwise and spanwise directions, while lowering their inclination angle with respect to the wall. When the boundary layer was returned to a zero pressure gradient following the favourable pressure gradient region, the turbulence level and the size and inclination of the structures returned to their canonical zero pressure gradient condition. The response of the boundary layer was somewhat faster in the rough-wall case, causing it to reach equilibrium in a shorter streamwise distance after the changes in pressure gradient than in the smooth-wall case. The adverse pressure gradient increased turbulence levels relative to the wall friction velocity, reduced the size of turbulence structures relative to the boundary layer thickness and increased their inclination angle. The changes with the adverse pressure gradient were significantly larger with the rough wall than the smooth. The results suggest that similarity might be achieved with adverse pressure gradients if smooth- and rough-wall cases with the same Clauser pressure gradient parameter history are compared.
Turbulent boundary layer flow over regularly and irregularly arranged truncated cone surfaces
- Kristofer M. Womack, Ralph J. Volino, Charles Meneveau, Michael P. Schultz
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- Journal:
- Journal of Fluid Mechanics / Volume 933 / 25 February 2022
- Published online by Cambridge University Press:
- 04 January 2022, A38
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Aiming to study the rough-wall turbulent boundary layer structure over differently arranged roughness elements, an experimental study was conducted on flows with regular and random roughness. Varying planform densities of truncated cone roughness elements in a square staggered pattern were investigated. The same planform densities were also investigated in random arrangements. Velocity statistics were measured via two-component laser Doppler velocimetry and stereoscopic particle image velocimetry. Friction velocity, thickness, roughness length and zero-plane displacement, determined from spatially averaged flow statistics, showed only minor differences between the regular and random arrangements at the same density. Recent a priori morphometric and statistical drag prediction methods were evaluated against experimentally determined roughness length. Observed differences between regular and random surface flow parameters were due to the presence of secondary flows which manifest as high-momentum pathways and low-momentum pathways in the streamwise velocity. Contrary to expectation, these secondary flows were present over the random surfaces and not discernible over the regular surfaces. Previously identified streamwise-coherent spanwise roughness heterogeneity does not seem to be present, suggesting that such roughness heterogeneity is not necessary to sustain secondary flows. Evidence suggests that the observed secondary flows were initiated at the front edge of the roughness and sustained over irregular roughness. Due to the secondary flows, local turbulent boundary layer profiles do not scale with local wall shear stress but appear to scale with local turbulent shear stress above the roughness canopy. Additionally, quadrant analysis shows distinct changes in the populations of ejection and sweep events.
Quaternary tephra from the Valles caldera in the volcanic field of the Jemez Mountains of New Mexico identified in western Canada
- John A. Westgate, Giday WoldeGabriel, Henry C. Halls, Colin J. Bray, René W. Barendregt, Nicholas J.G. Pearce, Andrei M. Sarna-Wojcicki, Michael P. Gorton, Richard E. Kelley, Emily Schultz-Fellenz
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- Journal:
- Quaternary Research / Volume 91 / Issue 2 / March 2019
- Published online by Cambridge University Press:
- 27 December 2018, pp. 813-828
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A fine-grained, up to 3-m-thick tephra bed in southwestern Saskatchewan, herein named Duncairn tephra (Dt), is derived from an early Pleistocene eruption in the Jemez Mountains volcanic field of New Mexico, requiring a trajectory of northward tephra dispersal of ~1500 km. An unusually low CaO content in its glass shards denies a source in the closer Yellowstone and Heise volcanic fields, whereas a Pleistocene tephra bed (LSMt) in the La Sal Mountains of Utah has a very similar glass chemistry to that of the Dt, supporting a more southerly source. Comprehensive characterization of these two distal tephra beds along with samples collected near the Valles caldera in New Mexico, including grain size, mineral assemblage, major- and trace-element composition of glass and minerals, paleomagnetism, and fission-track dating, justify this correlation. Two glass populations each exist in the Dt and LSMt. The proximal correlative of Dt1 is the plinian Tsankawi Pumice and co-ignimbritic ash of the first ignimbrite (Qbt1g) of the 1.24 Ma Tshirege Member of the Bandelier Tuff. The correlative of Dt2 and LSMt is the co-ignimbritic ash of Qbt2. Mixing of Dt1 and Dt2 probably occurred during northward transport in a jet stream.
Training for awareness of one's own spirituality: A key factor in overcoming barriers to the provision of spiritual care to advanced cancer patients by doctors and nurses
- Gil Bar-Sela, Michael J. Schultz, Karima Elshamy, Maryam Rassouli, Eran Ben-Arye, Myrna Doumit, Nahla Gafer, Alaa Albashayreh, Ibtisam Ghrayeb, Ibrahim Turker, Gulcin Ozalp, Sultan Kav, Rasha Fahmi, Sophia Nestoros, Hasanein Ghali, Layth Mula-Hussain, Ilana Shazar, Rana Obeidat, Rehana Punjwani, Mohamad Khleif, Gulbeyaz Can, Gonca Tuncel, Haris Charalambous, Safa Faraj, Neophyta Keoppi, Mazin Al-Jadiry, Sergey Postovsky, Ma'an Al-Omari, Samaher Razzaq, Hani Ayyash, Khaled Khader, Rejin Kebudi, Suha Omran, Osaid Rasheed, Mohammed Qadire, Ahmet Ozet, Michael Silbermann
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- Journal:
- Palliative & Supportive Care / Volume 17 / Issue 3 / June 2019
- Published online by Cambridge University Press:
- 06 September 2018, pp. 345-352
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Objective
When patients feel spiritually supported by staff, we find increased use of hospice and reduced use of aggressive treatments at end of life, yet substantial barriers to staff spiritual care provision still exist. We aimed to study these barriers in a new cultural context and analyzed a new subgroup with “unrealized potential” for improved spiritual care provision: those who are positively inclined toward spiritual care yet do not themselves provide it.
MethodWe distributed the Religion and Spirituality in Cancer Care Study via the Middle East Cancer Consortium to physicians and nurses caring for advanced cancer patients. Survey items included how often spiritual care should be provided, how often respondents themselves provide it, and perceived barriers to spiritual care provision.
ResultWe had 770 respondents (40% physicians, 60% nurses) from 14 Middle Eastern countries. The results showed that 82% of respondents think staff should provide spiritual care at least occasionally, but 44% provide spiritual care less often than they think they should. In multivariable analysis of respondents who valued spiritual care yet did not themselves provide it to their most recent patients, predictors included low personal sense of being spiritual (p < 0.001) and not having received training (p = 0.02; only 22% received training). How “developed” a country is negatively predicted spiritual care provision (p < 0.001). Self-perceived barriers were quite similar across cultures.
Significance of resultsDespite relatively high levels of spiritual care provision, we see a gap between desirability and actual provision. Seeing oneself as not spiritual or only slightly spiritual is a key factor demonstrably associated with not providing spiritual care. Efforts to increase spiritual care provision should target those in favor of spiritual care provision, promoting training that helps participants consider their own spirituality and the role that it plays in their personal and professional lives.
Differential analysis of capillary breakup rheometry for Newtonian liquids
- Louise L. McCarroll, Michael J. Solomon, William W. Schultz
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- Journal:
- Journal of Fluid Mechanics / Volume 804 / 10 October 2016
- Published online by Cambridge University Press:
- 08 September 2016, pp. 116-129
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We present a Newtonian, one-dimensional, differential analysis for capillary breakup rheometry (CBR) to determine the surface tension to viscosity ratio $\unicode[STIX]{x1D6FC}$. Our local differential analysis does not require specific assumptions for the axial force to preclude its measurement. Our analysis indicates that measuring gradients in filament curvature is necessary to accurately determine $\unicode[STIX]{x1D6FC}$ when axial force is not measured. CBR experiments were performed on five silicone oils ($0.35~\text{Pa}~\text{s}<\unicode[STIX]{x1D707}<10~\text{ Pa}~\text{s}$), three sample volumes, and three strains to evaluate the operating range of the differential analysis and compare its performance to that of a standard integral method from literature. We investigate the role of filament asymmetry, caused mainly by gravity, on the performance of the differential method for the range of conditions studied. Experimental and analytical details for resolving gradients of curvature are also given.
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- By Michael B. Abramowicz, John R. Allison, Kevin Emerson Collins, Christopher A. Cotropia, James E. Daily, John F. Duffy, Bronwyn H. Hall, Christopher M. Holman, F. Scott Kieff, Josh Lerner, Gerard N. Magliocca, Michael J. Meurer, Kristen Osenga, Arti K. Rai, Bhaven N. Sampat, Pamela Samuelson, Jason Schultz, Ted R. Sichelman
- Edited by Michael B. Abramowicz, James E. Daily, F. Scott Kieff
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- Book:
- Perspectives on Patentable Subject Matter
- Published online:
- 05 December 2014
- Print publication:
- 28 November 2014, pp vii-viii
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Effect of a brief emergency medicine education course on emergency department work intensity of family physicians
- Samuel Vaillancourt, Susan E. Schultz, Chad Leaver, Thérèse Stukel, Michael J. Schull
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- Journal:
- Canadian Journal of Emergency Medicine / Volume 15 / Issue 1 / January 2013
- Published online by Cambridge University Press:
- 04 March 2015, pp. 34-41
- Print publication:
- January 2013
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Background:
Recently, many Canadian emergency departments (EDs) have struggled with physician staffing shortages. In 2006, the Ontario Ministry of Health and Long-Term Care funded a brief “emergency medicine primer” (EMP) course for family physicians to upgrade or refresh skills, with the goal of increasing their ED work intensity. We sought to determine the effect of the EMP on the ED work intensity of family physicians.
Methods:A retrospective longitudinal study was conducted of the ED work of 239 family physicians in the 2 years before and after a minimum of 6 months and up to 2 years from completing an EMP course in 2006 to 2008 compared to non-EMP physicians. ED work intensity was defined as the number of ED shifts per month and the number of ED patients seen per month. We conducted two analyses: a before and after comparison of all EMP physicians and a matched cohort analysis matching each EMP physician to four non-EMP physicians on sex, year of medical school graduation, rurality, and pre-EMP ED work intensity.
Results:Postcourse, EMP physicians worked 0.5 more ED shifts per month (13% increase, p = 0.027). Compared to their matched controls, EMP physicians worked 0.7 more shifts per month (13% increase, p = 0.0032) and saw 15 more patients per month (17% increase, p = 0.0008) compared to matched non-EMP physicians. The greatest increases were among EMP physicians who were younger, were urban, had previous ED experience, or worked in a high-volume ED. The effect of the EMP course was negligible for physicians with no previous ED experience or working in rural areas.
Conclusion:The EMP course is associated with modest increases in ED work intensity among some family physicians, in particular younger physicians in urban areas. No increase was seen among physicians without previous ED experience or working in rural areas.
Efficacy of Retrospective Recall of Attention-Deficit Hyperactivity Disorder Symptoms: A Twin Study
- Mark R. Schultz, Keren Rabi, Stephen V. Faraone, William Kremen, Michael J. Lyons
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- Journal:
- Twin Research and Human Genetics / Volume 9 / Issue 2 / 01 April 2006
- Published online by Cambridge University Press:
- 21 February 2012, pp. 220-232
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Attention-deficit hyperactivity disorder (ADHD) is currently recognized as a neurobiological, genetically based disorder in both children and adults. In this article we examine whether, by using a sample of middle-aged male twin veterans, the phenotypic characterization, prevalence, heritability and the longitudinal course of the illness is comparable to results observed in samples of children and adolescents. We evaluated the utility of adult reports of lifetime ADHD symptoms by examining the heritability of retrospectively reported childhood symptoms, using both symptom-based and discrete classification- based approaches, as well as examining the persistence of ADHD symptoms into adulthood for that subsample of individuals who were judged to possibly have ADHD as children. Our results showed prevalence rates that were approximately similar to those observed in other studies, demonstrable familiality, similar item endorsement patterns, a strong genetic association between hyperactive and inattentive subtypes, and a longitudinal decline in symptom severity. We concluded that while assessing ADHD in adult probands may be less accurate than with children or adolescents, since it demonstrates several characteristics in common with other assessment techniques it remains a viable diagnostic and research strategy, even with population samples.
Turbulence structure in boundary layers over periodic two- and three-dimensional roughness
- RALPH J. VOLINO, MICHAEL P. SCHULTZ, KAREN A. FLACK
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- Journal:
- Journal of Fluid Mechanics / Volume 676 / 10 June 2011
- Published online by Cambridge University Press:
- 15 March 2011, pp. 172-190
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Measurements are presented from turbulent boundary layers over periodic two- and three-dimensional roughness. Cases with transverse rows of staggered cubes and cases with solid square transverse bars of two sizes were considered. Previous results by Volino, Schultz & Flack (J. Fluid Mech. vol. 635, 2009, p. 75) showed outer-layer similarity between cases with three-dimensional roughness and smooth walls, and deviations from similarity in cases with large two-dimensional transverse bars. The present results show that differences also occur with small two-dimensional bars and to a lesser extent when the bars are replaced with rows of staggered cubes. Differences are most apparent in correlations of turbulence quantities, which are of larger spatial extent for the rough-wall cases. The results with the staggered cubes indicate that part of the periodic roughness effect is caused by the repeated disturbance and recovery of the boundary layer as it encounters a row of roughness followed by a smooth surface. A larger effect, however, is due to the blockage caused by the two-dimensional transverse bars, which extend across the entire width of the boundary layer. The small two-dimensional bars have a larger effect than the staggered cubes, in spite of the bar height being only 11 viscous units and 1/7 of the cube height. The effect of the small bars extends well into the outer flow, indicating that effects observed previously with larger bars were not due only to a thickening of the roughness sublayer. The observed differences between the rough- and smooth-wall results are believed to be caused by large-scale attached eddies which extend from the roughness elements to the edge of the boundary layer.
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- By Rose Teteki Abbey, K. C. Abraham, David Tuesday Adamo, LeRoy H. Aden, Efrain Agosto, Victor Aguilan, Gillian T. W. Ahlgren, Charanjit Kaur AjitSingh, Dorothy B E A Akoto, Giuseppe Alberigo, Daniel E. Albrecht, Ruth Albrecht, Daniel O. Aleshire, Urs Altermatt, Anand Amaladass, Michael Amaladoss, James N. Amanze, Lesley G. Anderson, Thomas C. Anderson, Victor Anderson, Hope S. Antone, María Pilar Aquino, Paula Arai, Victorio Araya Guillén, S. Wesley Ariarajah, Ellen T. Armour, Brett Gregory Armstrong, Atsuhiro Asano, Naim Stifan Ateek, Mahmoud Ayoub, John Alembillah Azumah, Mercedes L. García Bachmann, Irena Backus, J. Wayne Baker, Mieke Bal, Lewis V. Baldwin, William Barbieri, António Barbosa da Silva, David Basinger, Bolaji Olukemi Bateye, Oswald Bayer, Daniel H. Bays, Rosalie Beck, Nancy Elizabeth Bedford, Guy-Thomas Bedouelle, Chorbishop Seely Beggiani, Wolfgang Behringer, Christopher M. Bellitto, Byard Bennett, Harold V. Bennett, Teresa Berger, Miguel A. Bernad, Henley Bernard, Alan E. Bernstein, Jon L. Berquist, Johannes Beutler, Ana María Bidegain, Matthew P. Binkewicz, Jennifer Bird, Joseph Blenkinsopp, Dmytro Bondarenko, Paulo Bonfatti, Riet en Pim Bons-Storm, Jessica A. Boon, Marcus J. Borg, Mark Bosco, Peter C. Bouteneff, François Bovon, William D. Bowman, Paul S. Boyer, David Brakke, Richard E. Brantley, Marcus Braybrooke, Ian Breward, Ênio José da Costa Brito, Jewel Spears Brooker, Johannes Brosseder, Nicholas Canfield Read Brown, Robert F. Brown, Pamela K. Brubaker, Walter Brueggemann, Bishop Colin O. Buchanan, Stanley M. Burgess, Amy Nelson Burnett, J. Patout Burns, David B. Burrell, David Buttrick, James P. Byrd, Lavinia Byrne, Gerado Caetano, Marcos Caldas, Alkiviadis Calivas, William J. Callahan, Salvatore Calomino, Euan K. Cameron, William S. Campbell, Marcelo Ayres Camurça, Daniel F. Caner, Paul E. Capetz, Carlos F. Cardoza-Orlandi, Patrick W. Carey, Barbara Carvill, Hal Cauthron, Subhadra Mitra Channa, Mark D. Chapman, James H. Charlesworth, Kenneth R. Chase, Chen Zemin, Luciano Chianeque, Philip Chia Phin Yin, Francisca H. Chimhanda, Daniel Chiquete, John T. Chirban, Soobin Choi, Robert Choquette, Mita Choudhury, Gerald Christianson, John Chryssavgis, Sejong Chun, Esther Chung-Kim, Charles M. A. Clark, Elizabeth A. Clark, Sathianathan Clarke, Fred Cloud, John B. Cobb, W. Owen Cole, John A Coleman, John J. Collins, Sylvia Collins-Mayo, Paul K. Conkin, Beth A. Conklin, Sean Connolly, Demetrios J. Constantelos, Michael A. Conway, Paula M. Cooey, Austin Cooper, Michael L. Cooper-White, Pamela Cooper-White, L. William Countryman, Sérgio Coutinho, Pamela Couture, Shannon Craigo-Snell, James L. Crenshaw, David Crowner, Humberto Horacio Cucchetti, Lawrence S. Cunningham, Elizabeth Mason Currier, Emmanuel Cutrone, Mary L. Daniel, David D. Daniels, Robert Darden, Rolf Darge, Isaiah Dau, Jeffry C. Davis, Jane Dawson, Valentin Dedji, John W. de Gruchy, Paul DeHart, Wendy J. Deichmann Edwards, Miguel A. De La Torre, George E. Demacopoulos, Thomas de Mayo, Leah DeVun, Beatriz de Vasconcellos Dias, Dennis C. Dickerson, John M. Dillon, Luis Miguel Donatello, Igor Dorfmann-Lazarev, Susanna Drake, Jonathan A. Draper, N. Dreher Martin, Otto Dreydoppel, Angelyn Dries, A. J. Droge, Francis X. D'Sa, Marilyn Dunn, Nicole Wilkinson Duran, Rifaat Ebied, Mark J. Edwards, William H. Edwards, Leonard H. Ehrlich, Nancy L. Eiesland, Martin Elbel, J. Harold Ellens, Stephen Ellingson, Marvin M. Ellison, Robert Ellsberg, Jean Bethke Elshtain, Eldon Jay Epp, Peter C. Erb, Tassilo Erhardt, Maria Erling, Noel Leo Erskine, Gillian R. Evans, Virginia Fabella, Michael A. Fahey, Edward Farley, Margaret A. Farley, Wendy Farley, Robert Fastiggi, Seena Fazel, Duncan S. Ferguson, Helwar Figueroa, Paul Corby Finney, Kyriaki Karidoyanes FitzGerald, Thomas E. FitzGerald, John R. Fitzmier, Marie Therese Flanagan, Sabina Flanagan, Claude Flipo, Ronald B. Flowers, Carole Fontaine, David Ford, Mary Ford, Stephanie A. Ford, Jim Forest, William Franke, Robert M. Franklin, Ruth Franzén, Edward H. Friedman, Samuel Frouisou, Lorelei F. Fuchs, Jojo M. Fung, Inger Furseth, Richard R. Gaillardetz, Brandon Gallaher, China Galland, Mark Galli, Ismael García, Tharscisse Gatwa, Jean-Marie Gaudeul, Luis María Gavilanes del Castillo, Pavel L. Gavrilyuk, Volney P. Gay, Metropolitan Athanasios Geevargis, Kondothra M. George, Mary Gerhart, Simon Gikandi, Maurice Gilbert, Michael J. Gillgannon, Verónica Giménez Beliveau, Terryl Givens, Beth Glazier-McDonald, Philip Gleason, Menghun Goh, Brian Golding, Bishop Hilario M. Gomez, Michelle A. Gonzalez, Donald K. Gorrell, Roy Gottfried, Tamara Grdzelidze, Joel B. Green, Niels Henrik Gregersen, Cristina Grenholm, Herbert Griffiths, Eric W. Gritsch, Erich S. Gruen, Christoffer H. Grundmann, Paul H. Gundani, Jon P. Gunnemann, Petre Guran, Vidar L. Haanes, Jeremiah M. Hackett, Getatchew Haile, Douglas John Hall, Nicholas Hammond, Daphne Hampson, Jehu J. Hanciles, Barry Hankins, Jennifer Haraguchi, Stanley S. Harakas, Anthony John Harding, Conrad L. Harkins, J. William Harmless, Marjory Harper, Amir Harrak, Joel F. Harrington, Mark W. Harris, Susan Ashbrook Harvey, Van A. Harvey, R. Chris Hassel, Jione Havea, Daniel Hawk, Diana L. Hayes, Leslie Hayes, Priscilla Hayner, S. Mark Heim, Simo Heininen, Richard P. Heitzenrater, Eila Helander, David Hempton, Scott H. Hendrix, Jan-Olav Henriksen, Gina Hens-Piazza, Carter Heyward, Nicholas J. Higham, David Hilliard, Norman A. Hjelm, Peter C. Hodgson, Arthur Holder, M. Jan Holton, Dwight N. Hopkins, Ronnie Po-chia Hsia, Po-Ho Huang, James Hudnut-Beumler, Jennifer S. Hughes, Leonard M. Hummel, Mary E. Hunt, Laennec Hurbon, Mark Hutchinson, Susan E. Hylen, Mary Beth Ingham, H. Larry Ingle, Dale T. Irvin, Jon Isaak, Paul John Isaak, Ada María Isasi-Díaz, Hans Raun Iversen, Margaret C. Jacob, Arthur James, Maria Jansdotter-Samuelsson, David Jasper, Werner G. Jeanrond, Renée Jeffery, David Lyle Jeffrey, Theodore W. Jennings, David H. Jensen, Robin Margaret Jensen, David Jobling, Dale A. Johnson, Elizabeth A. Johnson, Maxwell E. Johnson, Sarah Johnson, Mark D. Johnston, F. Stanley Jones, James William Jones, John R. Jones, Alissa Jones Nelson, Inge Jonsson, Jan Joosten, Elizabeth Judd, Mulambya Peggy Kabonde, Robert Kaggwa, Sylvester Kahakwa, Isaac Kalimi, Ogbu U. Kalu, Eunice Kamaara, Wayne C. Kannaday, Musimbi Kanyoro, Veli-Matti Kärkkäinen, Frank Kaufmann, Léon Nguapitshi Kayongo, Richard Kearney, Alice A. Keefe, Ralph Keen, Catherine Keller, Anthony J. Kelly, Karen Kennelly, Kathi Lynn Kern, Fergus Kerr, Edward Kessler, George Kilcourse, Heup Young Kim, Kim Sung-Hae, Kim Yong-Bock, Kim Yung Suk, Richard King, Thomas M. King, Robert M. Kingdon, Ross Kinsler, Hans G. Kippenberg, Cheryl A. Kirk-Duggan, Clifton Kirkpatrick, Leonid Kishkovsky, Nadieszda Kizenko, Jeffrey Klaiber, Hans-Josef Klauck, Sidney Knight, Samuel Kobia, Robert Kolb, Karla Ann Koll, Heikki Kotila, Donald Kraybill, Philip D. W. Krey, Yves Krumenacker, Jeffrey Kah-Jin Kuan, Simanga R. Kumalo, Peter Kuzmic, Simon Shui-Man Kwan, Kwok Pui-lan, André LaCocque, Stephen E. Lahey, John Tsz Pang Lai, Emiel Lamberts, Armando Lampe, Craig Lampe, Beverly J. Lanzetta, Eve LaPlante, Lizette Larson-Miller, Ariel Bybee Laughton, Leonard Lawlor, Bentley Layton, Robin A. Leaver, Karen Lebacqz, Archie Chi Chung Lee, Marilyn J. Legge, Hervé LeGrand, D. L. LeMahieu, Raymond Lemieux, Bill J. Leonard, Ellen M. Leonard, Outi Leppä, Jean Lesaulnier, Nantawan Boonprasat Lewis, Henrietta Leyser, Alexei Lidov, Bernard Lightman, Paul Chang-Ha Lim, Carter Lindberg, Mark R. Lindsay, James R. Linville, James C. Livingston, Ann Loades, David Loades, Jean-Claude Loba-Mkole, Lo Lung Kwong, Wati Longchar, Eleazar López, David W. Lotz, Andrew Louth, Robin W. Lovin, William Luis, Frank D. Macchia, Diarmaid N. J. MacCulloch, Kirk R. MacGregor, Marjory A. MacLean, Donald MacLeod, Tomas S. Maddela, Inge Mager, Laurenti Magesa, David G. Maillu, Fortunato Mallimaci, Philip Mamalakis, Kä Mana, Ukachukwu Chris Manus, Herbert Robinson Marbury, Reuel Norman Marigza, Jacqueline Mariña, Antti Marjanen, Luiz C. L. Marques, Madipoane Masenya (ngwan'a Mphahlele), Caleb J. D. Maskell, Steve Mason, Thomas Massaro, Fernando Matamoros Ponce, András Máté-Tóth, Odair Pedroso Mateus, Dinis Matsolo, Fumitaka Matsuoka, John D'Arcy May, Yelena Mazour-Matusevich, Theodore Mbazumutima, John S. McClure, Christian McConnell, Lee Martin McDonald, Gary B. McGee, Thomas McGowan, Alister E. McGrath, Richard J. McGregor, John A. McGuckin, Maud Burnett McInerney, Elsie Anne McKee, Mary B. McKinley, James F. McMillan, Ernan McMullin, Kathleen E. McVey, M. Douglas Meeks, Monica Jyotsna Melanchthon, Ilie Melniciuc-Puica, Everett Mendoza, Raymond A. Mentzer, William W. Menzies, Ina Merdjanova, Franziska Metzger, Constant J. Mews, Marvin Meyer, Carol Meyers, Vasile Mihoc, Gunner Bjerg Mikkelsen, Maria Inêz de Castro Millen, Clyde Lee Miller, Bonnie J. Miller-McLemore, Alexander Mirkovic, Paul Misner, Nozomu Miyahira, R. W. L. Moberly, Gerald Moede, Aloo Osotsi Mojola, Sunanda Mongia, Rebeca Montemayor, James Moore, Roger E. Moore, Craig E. Morrison O.Carm, Jeffry H. Morrison, Keith Morrison, Wilson J. Moses, Tefetso Henry Mothibe, Mokgethi Motlhabi, Fulata Moyo, Henry Mugabe, Jesse Ndwiga Kanyua Mugambi, Peggy Mulambya-Kabonde, Robert Bruce Mullin, Pamela Mullins Reaves, Saskia Murk Jansen, Heleen L. Murre-Van den Berg, Augustine Musopole, Isaac M. T. Mwase, Philomena Mwaura, Cecilia Nahnfeldt, Anne Nasimiyu Wasike, Carmiña Navia Velasco, Thulani Ndlazi, Alexander Negrov, James B. Nelson, David G. Newcombe, Carol Newsom, Helen J. Nicholson, George W. E. Nickelsburg, Tatyana Nikolskaya, Damayanthi M. A. Niles, Bertil Nilsson, Nyambura Njoroge, Fidelis Nkomazana, Mary Beth Norton, Christian Nottmeier, Sonene Nyawo, Anthère Nzabatsinda, Edward T. Oakes, Gerald O'Collins, Daniel O'Connell, David W. Odell-Scott, Mercy Amba Oduyoye, Kathleen O'Grady, Oyeronke Olajubu, Thomas O'Loughlin, Dennis T. Olson, J. Steven O'Malley, Cephas N. Omenyo, Muriel Orevillo-Montenegro, César Augusto Ornellas Ramos, Agbonkhianmeghe E. Orobator, Kenan B. Osborne, Carolyn Osiek, Javier Otaola Montagne, Douglas F. Ottati, Anna May Say Pa, Irina Paert, Jerry G. Pankhurst, Aristotle Papanikolaou, Samuele F. Pardini, Stefano Parenti, Peter Paris, Sung Bae Park, Cristián G. Parker, Raquel Pastor, Joseph Pathrapankal, Daniel Patte, W. Brown Patterson, Clive Pearson, Keith F. Pecklers, Nancy Cardoso Pereira, David Horace Perkins, Pheme Perkins, Edward N. Peters, Rebecca Todd Peters, Bishop Yeznik Petrossian, Raymond Pfister, Peter C. Phan, Isabel Apawo Phiri, William S. F. Pickering, Derrick G. Pitard, William Elvis Plata, Zlatko Plese, John Plummer, James Newton Poling, Ronald Popivchak, Andrew Porter, Ute Possekel, James M. Powell, Enos Das Pradhan, Devadasan Premnath, Jaime Adrían Prieto Valladares, Anne Primavesi, Randall Prior, María Alicia Puente Lutteroth, Eduardo Guzmão Quadros, Albert Rabil, Laurent William Ramambason, Apolonio M. Ranche, Vololona Randriamanantena Andriamitandrina, Lawrence R. Rast, Paul L. Redditt, Adele Reinhartz, Rolf Rendtorff, Pål Repstad, James N. Rhodes, John K. Riches, Joerg Rieger, Sharon H. Ringe, Sandra Rios, Tyler Roberts, David M. Robinson, James M. Robinson, Joanne Maguire Robinson, Richard A. H. Robinson, Roy R. Robson, Jack B. Rogers, Maria Roginska, Sidney Rooy, Rev. Garnett Roper, Maria José Fontelas Rosado-Nunes, Andrew C. Ross, Stefan Rossbach, François Rossier, John D. Roth, John K. Roth, Phillip Rothwell, Richard E. Rubenstein, Rosemary Radford Ruether, Markku Ruotsila, John E. Rybolt, Risto Saarinen, John Saillant, Juan Sanchez, Wagner Lopes Sanchez, Hugo N. Santos, Gerhard Sauter, Gloria L. Schaab, Sandra M. Schneiders, Quentin J. Schultze, Fernando F. Segovia, Turid Karlsen Seim, Carsten Selch Jensen, Alan P. F. Sell, Frank C. Senn, Kent Davis Sensenig, Damían Setton, Bal Krishna Sharma, Carolyn J. Sharp, Thomas Sheehan, N. Gerald Shenk, Christian Sheppard, Charles Sherlock, Tabona Shoko, Walter B. Shurden, Marguerite Shuster, B. Mark Sietsema, Batara Sihombing, Neil Silberman, Clodomiro Siller, Samuel Silva-Gotay, Heikki Silvet, John K. Simmons, Hagith Sivan, James C. Skedros, Abraham Smith, Ashley A. Smith, Ted A. Smith, Daud Soesilo, Pia Søltoft, Choan-Seng (C. S.) Song, Kathryn Spink, Bryan Spinks, Eric O. Springsted, Nicolas Standaert, Brian Stanley, Glen H. Stassen, Karel Steenbrink, Stephen J. Stein, Andrea Sterk, Gregory E. Sterling, Columba Stewart, Jacques Stewart, Robert B. Stewart, Cynthia Stokes Brown, Ken Stone, Anne Stott, Elizabeth Stuart, Monya Stubbs, Marjorie Hewitt Suchocki, David Kwang-sun Suh, Scott W. Sunquist, Keith Suter, Douglas Sweeney, Charles H. Talbert, Shawqi N. Talia, Elsa Tamez, Joseph B. Tamney, Jonathan Y. Tan, Yak-Hwee Tan, Kathryn Tanner, Feiya Tao, Elizabeth S. Tapia, Aquiline Tarimo, Claire Taylor, Mark Lewis Taylor, Bishop Abba Samuel Wolde Tekestebirhan, Eugene TeSelle, M. Thomas Thangaraj, David R. Thomas, Andrew Thornley, Scott Thumma, Marcelo Timotheo da Costa, George E. “Tink” Tinker, Ola Tjørhom, Karen Jo Torjesen, Iain R. Torrance, Fernando Torres-Londoño, Archbishop Demetrios [Trakatellis], Marit Trelstad, Christine Trevett, Phyllis Trible, Johannes Tromp, Paul Turner, Robert G. Tuttle, Archbishop Desmond Tutu, Peter Tyler, Anders Tyrberg, Justin Ukpong, Javier Ulloa, Camillus Umoh, Kristi Upson-Saia, Martina Urban, Monica Uribe, Elochukwu Eugene Uzukwu, Richard Vaggione, Gabriel Vahanian, Paul Valliere, T. J. Van Bavel, Steven Vanderputten, Peter Van der Veer, Huub Van de Sandt, Louis Van Tongeren, Luke A. Veronis, Noel Villalba, Ramón Vinke, Tim Vivian, David Voas, Elena Volkova, Katharina von Kellenbach, Elina Vuola, Timothy Wadkins, Elaine M. Wainwright, Randi Jones Walker, Dewey D. Wallace, Jerry Walls, Michael J. Walsh, Philip Walters, Janet Walton, Jonathan L. Walton, Wang Xiaochao, Patricia A. Ward, David Harrington Watt, Herold D. Weiss, Laurence L. Welborn, Sharon D. Welch, Timothy Wengert, Traci C. West, Merold Westphal, David Wetherell, Barbara Wheeler, Carolinne White, Jean-Paul Wiest, Frans Wijsen, Terry L. Wilder, Felix Wilfred, Rebecca Wilkin, Daniel H. Williams, D. Newell Williams, Michael A. Williams, Vincent L. Wimbush, Gabriele Winkler, Anders Winroth, Lauri Emílio Wirth, James A. Wiseman, Ebba Witt-Brattström, Teofil Wojciechowski, John Wolffe, Kenman L. Wong, Wong Wai Ching, Linda Woodhead, Wendy M. Wright, Rose Wu, Keith E. Yandell, Gale A. Yee, Viktor Yelensky, Yeo Khiok-Khng, Gustav K. K. Yeung, Angela Yiu, Amos Yong, Yong Ting Jin, You Bin, Youhanna Nessim Youssef, Eliana Yunes, Robert Michael Zaller, Valarie H. Ziegler, Barbara Brown Zikmund, Joyce Ann Zimmerman, Aurora Zlotnik, Zhuo Xinping
- Edited by Daniel Patte, Vanderbilt University, Tennessee
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- Book:
- The Cambridge Dictionary of Christianity
- Published online:
- 05 August 2012
- Print publication:
- 20 September 2010, pp xi-xliv
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Subjective utility ratings of neuroleptics in treating schizophrenia*
- Stephen E. Finn, J. Michael Bailey, Robert T. Schultz, Raymond Faber
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- Journal:
- Psychological Medicine / Volume 20 / Issue 4 / November 1990
- Published online by Cambridge University Press:
- 09 July 2009, pp. 843-848
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This study developed a method for measuring subjective costs and benefits of psychiatric treatments. Forty-one patients rated the relative bothersomeness of symptoms of schizophrenia and side effects of neuroleptics. Thirty-four psychiatrists made parallel ratings from the perspective of the average patient (individual utility) and of the patient's family and society (institutional utility). Psychiatrists predicted patients' ratings moderately well, but misjudged the bothersomeness to patients of 24% of side effects and 20% of symptoms. When considering the patient's perspective, both schizophrenic patients and psychiatrists rated symptoms as no more bothersome than side effects. However, psychiatrists saw side effects as significantly less bothersome than symptoms when considering costs to society. The subjective utility of neuroleptic medications for schizophrenia is most justifiable from an institutional perspective.
Contributors
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- By Donald Addington, Jean Addington, Kelly Allott, Amanda Baker, Gregor Berger, Michael Berk, Max Birchwood, Warrick J. Brewer, Peter Burnett, Tyrone Cannon, Andrew Chanen, Philippe Conus, Barbara Cornblatt, Thomas Craig, Alex Fornito, David Fowler, Shona M. Francey, John Gleeson, Susy Harrigan, Meredith Harris, Leanne Hides, Christian G. Huber, Henry J. Jackson, Anthony F. Jorm, Eóin Killackey, Joachim Klosterkötter, Martin Lambert, Tim Lambert, Shon Lewis, Don Linszen, Dan Lubman, Nellie Lucas, Craig Macneil, Ashok K. Malla, Max Marshall, Louise K. McCutcheon, Patrick D. McGorry, Catharine McNab, Maria Michail, Anthony P. Morrison, Merete Nordentoft, Ross M. G. Norman, Keith H. Nuechterlein, Christos Pantelis, Lisa J. Phillips, Richie Poulton, Paddy Power, Jo Robinson, Frauke Schultze-Lutter, Jim van Os, José Luis Vázquez-Barquero, Dennis Velakoulis, Darryl Wade, Daniel Weinberger, Durk Wiersma, Stephen J. Wood, Annemarie Wright, Murat Yücel, Alison R. Yung, Robert B. Zipursky
- Edited by Henry J. Jackson, University of Melbourne, Patrick D. McGorry
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- Book:
- The Recognition and Management of Early Psychosis
- Published online:
- 10 August 2009
- Print publication:
- 19 February 2009, pp xi-xvi
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Azimuthal structure of turbulence in high Reynolds number pipe flow
- SEAN C. C. BAILEY, MARCUS HULTMARK, ALEXANDER J. SMITS, MICHAEL P. SCHULTZ
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- Journal:
- Journal of Fluid Mechanics / Volume 615 / 25 November 2008
- Published online by Cambridge University Press:
- 25 November 2008, pp. 121-138
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Two-point hot-wire measurements of streamwise velocity were performed in the logarithmic and wake regions of turbulent pipe flow for Reynolds numbers, based on pipe diameter, ranging from 7.6 × 104 to 8.3 × 106 at four wall-normal positions with azimuthal probe separation. The azimuthal correlations were found to be consistent with the presence of very large-scale coherent regions of low-wavenumber, low-momentum fluid observed in previous studies of wall-bounded flows and were found to be independent of changing Reynolds number and surface roughness effects. At the edge of the logarithmic layer the azimuthal scale determined from the correlations was found to be similar to that observed for channel flows but larger than that observed for boundary layers, inconsistent with the concept of a universal logarithmic region. As the wall-normal position increased outside the logarithmic layer, there was a decrease in azimuthal scale relative to that of channel flow. Using cross-spectral analysis, high-wavenumber motion was found to grow azimuthally with wall-normal distance at a faster rate than the low-wavenumber motions.
Contributors
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- By Jeremy Ackerman, Polly Bijur, Hans Bradshaw, Ciaran J. Browne, John H. Burton, Lisa Calder, David Cline, Rita K. Cydulka, Deborah B. Diercks, James Ducharme, Megan L. Fix, Michel Galinski, Ula Hwang, Jonathan S. Ilgen, Andy Jagoda, Samuel Kim, Robert Knopp, Jason B. Lester, Adam Levine, Todd M. Listwa, Frank LoVecchio, Sharon E. Mace, Alan P. Marco, Catherine A. Marco, Chris McEachin, James R. Miner, Kalani Olmsted, Sohan Parekh, Peter Rosen, Michael S. Runyon, Michael T. Schultz, Adam J. Singer, Robert A. Swor, Joshua H. Tamayo-Sarver, Stephen H. Thomas, Michael Turturro, Michael Walta, Benjamin A. White, Beth Wicklund, Susan R. Wilcox, Nathanael Wood, Dale P. Woolridge, Andrew Worster, Janet Simmons Young, Kelly Young
- Edited by Stephen H. Thomas
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- Book:
- Emergency Department Analgesia
- Published online:
- 18 December 2009
- Print publication:
- 25 September 2008, pp viii-xii
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The NASA EPOXI mission of opportunity to gather ultraprecise photometry of known transiting exoplanets
- Jessie L. Christiansen, David Charbonneau, Michael F. A'Hearn, Drake Deming, Matthew J. Holman, Sarah Ballard, David T. F. Weldrake, Richard K. Barry, Marc J. Kuchner, Timothy A. Livengood, Jeffrey Pedelty, Alfred Schultz, Tilak Hewagama, Jessica M. Sunshine, Dennis D. Wellnitz, Don L. Hampton, Carey M. Lisse, Sara Seager, Joseph F. Veverka
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- Journal:
- Proceedings of the International Astronomical Union / Volume 4 / Issue S253 / May 2008
- Published online by Cambridge University Press:
- 01 May 2008, pp. 301-307
- Print publication:
- May 2008
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The NASA Discovery mission EPOXI, utilizing the Deep Impact flyby spacecraft, comprises two phases: EPOCh (Extrasolar Planet Observation and Characterization) and DIXI (Deep Impact eXtended Investigation). With EPOCh, we use the 30-cm high resolution visible imager to obtain ultraprecise photometric light curves of known transiting planet systems. We will analyze these data for evidence of additional planets, via transit timing variations or transits; for planetary moons or rings; for detection of secondary eclipses and the constraint of geometric planetary albedos; and for refinement of the system parameters. Over a period of four months, EPOCh observed four known transiting planet systems, with each system observed continuously for several weeks. Here we present an overview of EPOCh, including the spacecraft and science goals, and preliminary photometry results.
Preliminary Results on HAT-P-4, TrES-3, XO-2, and GJ 436 from the NASA EPOXI Mission
- Sarah Ballard, David Charbonneau, Michael F. A'Hearn, Drake Deming, Matthew J. Holman, Jessie L. Christiansen, David T. F. Weldrake, Richard K. Barry, Marc J. Kuchner, Timothy A. Livengood, Jeffrey Pedelty, Alfred Schultz, Tilak Hewagama, Jessica M. Sunshine, Dennis D. Wellnitz, Don L. Hampton, Carey M. Lisse, Sara Seager, Joseph F. Veverka
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- Journal:
- Proceedings of the International Astronomical Union / Volume 4 / Issue S253 / May 2008
- Published online by Cambridge University Press:
- 01 May 2008, pp. 470-473
- Print publication:
- May 2008
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EPOXI (EPOCh + DIXI) is a NASA Discovery Program Mission of Opportunity using the Deep Impact flyby spacecraft. The EPOCh (Extrasolar Planet Observation and Characterization) Science Investigation will gather photometric time series of known transiting exoplanet systems from January through August 2008. Here we describe the steps in the photometric extraction of the time series and present preliminary results of the first four EPOCh targets.
Crystal structure of a model branchpoint–U2 snRNA duplex containing bulged adenosines
- J. ANDREW BERGLUND, MICHAEL ROSBASH, STEVE C. SCHULTZ
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Bulged nucleotides play a variety of important roles in RNA structure and function, frequently forming tertiary interactions and sometimes even participating in RNA catalysis. In pre-mRNA splicing, the U2 snRNA base pairs with the intron branchpoint sequence (BPS) to form a short RNA duplex that contains a bulged adenosine that ultimately serves as the nucleophile that attacks the 5′ splice site. We have determined a 2.18-Å resolution crystal structure of a self-complementary RNA designed to mimic the highly conserved yeast (Saccharomyces cerevisiae) branchpoint sequence (5′-UACUA
A CGUAGUA with the BPS italicized and the branchsite adenosine underlined) base paired with its complementary sequence from U2 snRNA. The structure shows a nearly ideal A-form helix from which two unpaired adenosines flip out. Although the adenosine adjacent to the branchsite adenosine is the one bulged out in the structure described here, either of these adenosines can serve as the nucleophile in mammalian but not in yeast pre-mRNA splicing. In addition, the packing of the bulged RNA helices within the crystal reveals a novel RNA tertiary interaction in which three RNA helices interact through bulged adenosines in the absence of any divalent metal ions.