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Plants and Subsistence during the Fluted-Point Period of the Northeast
- Nathaniel R. Kitchel, Madeline E. Mackie
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- Journal:
- American Antiquity / Volume 87 / Issue 2 / April 2022
- Published online by Cambridge University Press:
- 01 December 2021, pp. 368-376
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- April 2022
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The role of plant foods during the fluted-point period (FPP) of North America is contested. Central to this debate is whether the scarcity of FPP macrobotanical materials stems from poor preservation of archaeological features and the macrobotanical remains they might contain or from the limited use of plants during the FPP. Employing summed probability distributions of radiocarbon date frequencies in northeastern North America, we find that FPP hearths are as common as expected, given the small number of well-dated FPP sites in the region. A second comparison shows that northeastern FPP hearths contain macrobotanical remains at a higher frequency than hearths from a region with better preservation and where small seeds formed a part of the diet. The macrobotanical materials so far recovered from FPP hearths in the Northeast show that plant foods contributed to diets during the FPP but that the plant diet breadth was relatively narrow, consistent with a specialized caribou hunting lifeway.
Addressing personal protective equipment (PPE) decontamination: Methylene blue and light inactivates severe acute respiratory coronavirus virus 2 (SARS-CoV-2) on N95 respirators and medical masks with maintenance of integrity and fit
- Part of
- Thomas Sean Lendvay, James Chen, Brian H. Harcourt, Florine E. M. Scholte, Ying Ling Lin, F. Selcen Kilinc-Balci, Molly M. Lamb, Kamonthip Homdayjanakul, Yi Cui, Amy Price, Belinda Heyne, Jaya Sahni, Kareem B. Kabra, Yi-Chan Lin, David Evans, Christopher N. Mores, Ken Page, Larry F. Chu, Eric Haubruge, Etienne Thiry, Louisa F. Ludwig-Begall, Constance Wielick, Tanner Clark, Thor Wagner, Emily Timm, Thomas Gallagher, Peter Faris, Nicolas Macia, Cyrus J. Mackie, Sarah M. Simmons, Susan Reader, Rebecca Malott, Karen Hope, Jan M. Davies, Sarah R. Tritsch, Lorène Dams, Hans Nauwynck, Jean-Francois Willaert, Simon De Jaeger, Lei Liao, Mervin Zhao, Jan Laperre, Olivier Jolois, Sarah J. Smit, Alpa N. Patel, Mark Mayo, Rod Parker, Vanessa Molloy-Simard, Jean-Luc Lemyre, Steven Chu, John M. Conly, May C. Chu
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- Journal:
- Infection Control & Hospital Epidemiology / Volume 43 / Issue 7 / July 2022
- Published online by Cambridge University Press:
- 21 May 2021, pp. 876-885
- Print publication:
- July 2022
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Objective:
The coronavirus disease 2019 (COVID-19) pandemic has resulted in shortages of personal protective equipment (PPE), underscoring the urgent need for simple, efficient, and inexpensive methods to decontaminate masks and respirators exposed to severe acute respiratory coronavirus virus 2 (SARS-CoV-2). We hypothesized that methylene blue (MB) photochemical treatment, which has various clinical applications, could decontaminate PPE contaminated with coronavirus.
Design:The 2 arms of the study included (1) PPE inoculation with coronaviruses followed by MB with light (MBL) decontamination treatment and (2) PPE treatment with MBL for 5 cycles of decontamination to determine maintenance of PPE performance.
Methods:MBL treatment was used to inactivate coronaviruses on 3 N95 filtering facepiece respirator (FFR) and 2 medical mask models. We inoculated FFR and medical mask materials with 3 coronaviruses, including SARS-CoV-2, and we treated them with 10 µM MB and exposed them to 50,000 lux of white light or 12,500 lux of red light for 30 minutes. In parallel, integrity was assessed after 5 cycles of decontamination using multiple US and international test methods, and the process was compared with the FDA-authorized vaporized hydrogen peroxide plus ozone (VHP+O3) decontamination method.
Results:Overall, MBL robustly and consistently inactivated all 3 coronaviruses with 99.8% to >99.9% virus inactivation across all FFRs and medical masks tested. FFR and medical mask integrity was maintained after 5 cycles of MBL treatment, whereas 1 FFR model failed after 5 cycles of VHP+O3.
Conclusions:MBL treatment decontaminated respirators and masks by inactivating 3 tested coronaviruses without compromising integrity through 5 cycles of decontamination. MBL decontamination is effective, is low cost, and does not require specialized equipment, making it applicable in low- to high-resource settings.
Cross-linking of sodium caseinate-structured emulsion with transglutaminase alters postprandial metabolic and appetite responses in healthy young individuals
- Kristiina R. Juvonen, Adam Macierzanka, Martina E. Lille, David E. Laaksonen, Hannu M. Mykkänen, Leo K. Niskanen, Jussi Pihlajamäki, Kari A. Mäkelä, Clare E. N. Mills, Alan R. Mackie, Paul Malcolm, Karl-Heinz Herzig, Kaisa S. Poutanen, Leila J. Karhunen
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- Journal:
- British Journal of Nutrition / Volume 114 / Issue 3 / 14 August 2015
- Published online by Cambridge University Press:
- 10 July 2015, pp. 418-429
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- 14 August 2015
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The physico-chemical and interfacial properties of fat emulsions influence lipid digestion and may affect postprandial responses. The aim of the present study was to determine the effects of the modification of the interfacial layer of a fat emulsion by cross-linking on postprandial metabolic and appetite responses. A total of fifteen healthy individuals (26·5 (sem 6·9) years and BMI 21·9 (sem 2·0) kg/m2) participated in a cross-over design experiment in which they consumed two isoenergetic (1924 kJ (460 kcal)) and isovolumic (250 g) emulsions stabilised with either sodium caseinate (Cas) or transglutaminase-cross-linked sodium caseinate (Cas-TG) in a randomised order. Blood samples were collected from the individuals at baseline and for 6 h postprandially for the determination of serum TAG and plasma NEFA, cholecystokinin (CCK), glucagon-like peptide 1 (GLP-1), glucose and insulin responses. Appetite was assessed using visual analogue scales. Postprandial TAG and NEFA responses and gastric emptying (GE) rates were comparable between the emulsions. CCK increased more after the ingestion of Cas-TG than after the ingestion of Cas (P< 0·05), while GLP-1 responses did not differ between the two test emulsions. Glucose and insulin profiles were lower after consuming Cas-TG than after consuming Cas (P< 0·05). The overall insulin, glucose and CCK responses, expressed as areas above/under the curve, did not differ significantly between the Cas and Cas-TG meal conditions. Satiety ratings were reduced and hunger, desire to eat and thirst ratings increased more after the ingestion of Cas-TG than after the ingestion of Cas (P< 0·05). The present results suggest that even a subtle structural modification of the interfacial layer of a fat emulsion can alter the early postprandial profiles of glucose, insulin, CCK, appetite and satiety through decreased protein digestion without affecting significantly on GE or overall lipid digestion.
Contributors
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- By Mitchell Aboulafia, Frederick Adams, Marilyn McCord Adams, Robert M. Adams, Laird Addis, James W. Allard, David Allison, William P. Alston, Karl Ameriks, C. Anthony Anderson, David Leech Anderson, Lanier Anderson, Roger Ariew, David Armstrong, Denis G. Arnold, E. J. Ashworth, Margaret Atherton, Robin Attfield, Bruce Aune, Edward Wilson Averill, Jody Azzouni, Kent Bach, Andrew Bailey, Lynne Rudder Baker, Thomas R. Baldwin, Jon Barwise, George Bealer, William Bechtel, Lawrence C. Becker, Mark A. Bedau, Ernst Behler, José A. Benardete, Ermanno Bencivenga, Jan Berg, Michael Bergmann, Robert L. Bernasconi, Sven Bernecker, Bernard Berofsky, Rod Bertolet, Charles J. Beyer, Christian Beyer, Joseph Bien, Joseph Bien, Peg Birmingham, Ivan Boh, James Bohman, Daniel Bonevac, Laurence BonJour, William J. Bouwsma, Raymond D. Bradley, Myles Brand, Richard B. Brandt, Michael E. Bratman, Stephen E. Braude, Daniel Breazeale, Angela Breitenbach, Jason Bridges, David O. Brink, Gordon G. Brittan, Justin Broackes, Dan W. Brock, Aaron Bronfman, Jeffrey E. Brower, Bartosz Brozek, Anthony Brueckner, Jeffrey Bub, Lara Buchak, Otavio Bueno, Ann E. Bumpus, Robert W. Burch, John Burgess, Arthur W. Burks, Panayot Butchvarov, Robert E. Butts, Marina Bykova, Patrick Byrne, David Carr, Noël Carroll, Edward S. Casey, Victor Caston, Victor Caston, Albert Casullo, Robert L. Causey, Alan K. L. Chan, Ruth Chang, Deen K. Chatterjee, Andrew Chignell, Roderick M. Chisholm, Kelly J. Clark, E. J. Coffman, Robin Collins, Brian P. Copenhaver, John Corcoran, John Cottingham, Roger Crisp, Frederick J. Crosson, Antonio S. Cua, Phillip D. Cummins, Martin Curd, Adam Cureton, Andrew Cutrofello, Stephen Darwall, Paul Sheldon Davies, Wayne A. Davis, Timothy Joseph Day, Claudio de Almeida, Mario De Caro, Mario De Caro, John Deigh, C. F. Delaney, Daniel C. Dennett, Michael R. DePaul, Michael Detlefsen, Daniel Trent Devereux, Philip E. Devine, John M. Dillon, Martin C. Dillon, Robert DiSalle, Mary Domski, Alan Donagan, Paul Draper, Fred Dretske, Mircea Dumitru, Wilhelm Dupré, Gerald Dworkin, John Earman, Ellery Eells, Catherine Z. Elgin, Berent Enç, Ronald P. Endicott, Edward Erwin, John Etchemendy, C. Stephen Evans, Susan L. Feagin, Solomon Feferman, Richard Feldman, Arthur Fine, Maurice A. Finocchiaro, William FitzPatrick, Richard E. Flathman, Gvozden Flego, Richard Foley, Graeme Forbes, Rainer Forst, Malcolm R. Forster, Daniel Fouke, Patrick Francken, Samuel Freeman, Elizabeth Fricker, Miranda Fricker, Michael Friedman, Michael Fuerstein, Richard A. Fumerton, Alan Gabbey, Pieranna Garavaso, Daniel Garber, Jorge L. A. Garcia, Robert K. Garcia, Don Garrett, Philip Gasper, Gerald Gaus, Berys Gaut, Bernard Gert, Roger F. Gibson, Cody Gilmore, Carl Ginet, Alan H. Goldman, Alvin I. Goldman, Alfonso Gömez-Lobo, Lenn E. Goodman, Robert M. Gordon, Stefan Gosepath, Jorge J. E. Gracia, Daniel W. Graham, George A. Graham, Peter J. Graham, Richard E. Grandy, I. Grattan-Guinness, John Greco, Philip T. Grier, Nicholas Griffin, Nicholas Griffin, David A. Griffiths, Paul J. Griffiths, Stephen R. Grimm, Charles L. Griswold, Charles B. Guignon, Pete A. Y. Gunter, Dimitri Gutas, Gary Gutting, Paul Guyer, Kwame Gyekye, Oscar A. Haac, Raul Hakli, Raul Hakli, Michael Hallett, Edward C. Halper, Jean Hampton, R. James Hankinson, K. R. Hanley, Russell Hardin, Robert M. Harnish, William Harper, David Harrah, Kevin Hart, Ali Hasan, William Hasker, John Haugeland, Roger Hausheer, William Heald, Peter Heath, Richard Heck, John F. Heil, Vincent F. Hendricks, Stephen Hetherington, Francis Heylighen, Kathleen Marie Higgins, Risto Hilpinen, Harold T. Hodes, Joshua Hoffman, Alan Holland, Robert L. Holmes, Richard Holton, Brad W. Hooker, Terence E. Horgan, Tamara Horowitz, Paul Horwich, Vittorio Hösle, Paul Hoβfeld, Daniel Howard-Snyder, Frances Howard-Snyder, Anne Hudson, Deal W. Hudson, Carl A. Huffman, David L. Hull, Patricia Huntington, Thomas Hurka, Paul Hurley, Rosalind Hursthouse, Guillermo Hurtado, Ronald E. Hustwit, Sarah Hutton, Jonathan Jenkins Ichikawa, Harry A. Ide, David Ingram, Philip J. Ivanhoe, Alfred L. Ivry, Frank Jackson, Dale Jacquette, Joseph Jedwab, Richard Jeffrey, David Alan Johnson, Edward Johnson, Mark D. Jordan, Richard Joyce, Hwa Yol Jung, Robert Hillary Kane, Tomis Kapitan, Jacquelyn Ann K. Kegley, James A. Keller, Ralph Kennedy, Sergei Khoruzhii, Jaegwon Kim, Yersu Kim, Nathan L. King, Patricia Kitcher, Peter D. Klein, E. D. Klemke, Virginia Klenk, George L. Kline, Christian Klotz, Simo Knuuttila, Joseph J. Kockelmans, Konstantin Kolenda, Sebastian Tomasz Kołodziejczyk, Isaac Kramnick, Richard Kraut, Fred Kroon, Manfred Kuehn, Steven T. Kuhn, Henry E. Kyburg, John Lachs, Jennifer Lackey, Stephen E. Lahey, Andrea Lavazza, Thomas H. Leahey, Joo Heung Lee, Keith Lehrer, Dorothy Leland, Noah M. Lemos, Ernest LePore, Sarah-Jane Leslie, Isaac Levi, Andrew Levine, Alan E. Lewis, Daniel E. Little, Shu-hsien Liu, Shu-hsien Liu, Alan K. L. Chan, Brian Loar, Lawrence B. Lombard, John Longeway, Dominic McIver Lopes, Michael J. Loux, E. J. Lowe, Steven Luper, Eugene C. Luschei, William G. Lycan, David Lyons, David Macarthur, Danielle Macbeth, Scott MacDonald, Jacob L. Mackey, Louis H. Mackey, Penelope Mackie, Edward H. Madden, Penelope Maddy, G. B. Madison, Bernd Magnus, Pekka Mäkelä, Rudolf A. Makkreel, David Manley, William E. Mann (W.E.M.), Vladimir Marchenkov, Peter Markie, Jean-Pierre Marquis, Ausonio Marras, Mike W. Martin, A. P. Martinich, William L. McBride, David McCabe, Storrs McCall, Hugh J. McCann, Robert N. McCauley, John J. McDermott, Sarah McGrath, Ralph McInerny, Daniel J. McKaughan, Thomas McKay, Michael McKinsey, Brian P. McLaughlin, Ernan McMullin, Anthonie Meijers, Jack W. Meiland, William Jason Melanson, Alfred R. Mele, Joseph R. Mendola, Christopher Menzel, Michael J. Meyer, Christian B. Miller, David W. Miller, Peter Millican, Robert N. Minor, Phillip Mitsis, James A. Montmarquet, Michael S. Moore, Tim Moore, Benjamin Morison, Donald R. Morrison, Stephen J. Morse, Paul K. Moser, Alexander P. D. Mourelatos, Ian Mueller, James Bernard Murphy, Mark C. Murphy, Steven Nadler, Jan Narveson, Alan Nelson, Jerome Neu, Samuel Newlands, Kai Nielsen, Ilkka Niiniluoto, Carlos G. Noreña, Calvin G. Normore, David Fate Norton, Nikolaj Nottelmann, Donald Nute, David S. Oderberg, Steve Odin, Michael O’Rourke, Willard G. Oxtoby, Heinz Paetzold, George S. Pappas, Anthony J. Parel, Lydia Patton, R. P. Peerenboom, Francis Jeffry Pelletier, Adriaan T. Peperzak, Derk Pereboom, Jaroslav Peregrin, Glen Pettigrove, Philip Pettit, Edmund L. Pincoffs, Andrew Pinsent, Robert B. Pippin, Alvin Plantinga, Louis P. Pojman, Richard H. Popkin, John F. Post, Carl J. Posy, William J. Prior, Richard Purtill, Michael Quante, Philip L. Quinn, Philip L. Quinn, Elizabeth S. Radcliffe, Diana Raffman, Gerard Raulet, Stephen L. Read, Andrews Reath, Andrew Reisner, Nicholas Rescher, Henry S. Richardson, Robert C. Richardson, Thomas Ricketts, Wayne D. Riggs, Mark Roberts, Robert C. Roberts, Luke Robinson, Alexander Rosenberg, Gary Rosenkranz, Bernice Glatzer Rosenthal, Adina L. Roskies, William L. Rowe, T. M. Rudavsky, Michael Ruse, Bruce Russell, Lilly-Marlene Russow, Dan Ryder, R. M. Sainsbury, Joseph Salerno, Nathan Salmon, Wesley C. Salmon, Constantine Sandis, David H. Sanford, Marco Santambrogio, David Sapire, Ruth A. Saunders, Geoffrey Sayre-McCord, Charles Sayward, James P. Scanlan, Richard Schacht, Tamar Schapiro, Frederick F. Schmitt, Jerome B. Schneewind, Calvin O. Schrag, Alan D. Schrift, George F. Schumm, Jean-Loup Seban, David N. Sedley, Kenneth Seeskin, Krister Segerberg, Charlene Haddock Seigfried, Dennis M. Senchuk, James F. Sennett, William Lad Sessions, Stewart Shapiro, Tommie Shelby, Donald W. Sherburne, Christopher Shields, Roger A. Shiner, Sydney Shoemaker, Robert K. Shope, Kwong-loi Shun, Wilfried Sieg, A. John Simmons, Robert L. Simon, Marcus G. Singer, Georgette Sinkler, Walter Sinnott-Armstrong, Matti T. Sintonen, Lawrence Sklar, Brian Skyrms, Robert C. Sleigh, Michael Anthony Slote, Hans Sluga, Barry Smith, Michael Smith, Robin Smith, Robert Sokolowski, Robert C. Solomon, Marta Soniewicka, Philip Soper, Ernest Sosa, Nicholas Southwood, Paul Vincent Spade, T. L. S. Sprigge, Eric O. Springsted, George J. Stack, Rebecca Stangl, Jason Stanley, Florian Steinberger, Sören Stenlund, Christopher Stephens, James P. Sterba, Josef Stern, Matthias Steup, M. A. Stewart, Leopold Stubenberg, Edith Dudley Sulla, Frederick Suppe, Jere Paul Surber, David George Sussman, Sigrún Svavarsdóttir, Zeno G. Swijtink, Richard Swinburne, Charles C. Taliaferro, Robert B. Talisse, John Tasioulas, Paul Teller, Larry S. Temkin, Mark Textor, H. S. Thayer, Peter Thielke, Alan Thomas, Amie L. Thomasson, Katherine Thomson-Jones, Joshua C. Thurow, Vzalerie Tiberius, Terrence N. Tice, Paul Tidman, Mark C. Timmons, William Tolhurst, James E. Tomberlin, Rosemarie Tong, Lawrence Torcello, Kelly Trogdon, J. D. Trout, Robert E. Tully, Raimo Tuomela, John Turri, Martin M. Tweedale, Thomas Uebel, Jennifer Uleman, James Van Cleve, Harry van der Linden, Peter van Inwagen, Bryan W. Van Norden, René van Woudenberg, Donald Phillip Verene, Samantha Vice, Thomas Vinci, Donald Wayne Viney, Barbara Von Eckardt, Peter B. M. Vranas, Steven J. Wagner, William J. Wainwright, Paul E. Walker, Robert E. Wall, Craig Walton, Douglas Walton, Eric Watkins, Richard A. Watson, Michael V. Wedin, Rudolph H. Weingartner, Paul Weirich, Paul J. Weithman, Carl Wellman, Howard Wettstein, Samuel C. Wheeler, Stephen A. White, Jennifer Whiting, Edward R. Wierenga, Michael Williams, Fred Wilson, W. Kent Wilson, Kenneth P. Winkler, John F. Wippel, Jan Woleński, Allan B. Wolter, Nicholas P. Wolterstorff, Rega Wood, W. Jay Wood, Paul Woodruff, Alison Wylie, Gideon Yaffe, Takashi Yagisawa, Yutaka Yamamoto, Keith E. Yandell, Xiaomei Yang, Dean Zimmerman, Günter Zoller, Catherine Zuckert, Michael Zuckert, Jack A. Zupko (J.A.Z.)
- Edited by Robert Audi, University of Notre Dame, Indiana
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- The Cambridge Dictionary of Philosophy
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- 05 August 2015
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- 27 April 2015, pp ix-xxx
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Contributors
- Edited by Claudio López-Guerra, Julia Maskivker, Rollins College, Florida
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- Rationality, Democracy, and Justice
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- 05 January 2015
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- 05 February 2015, pp vii-x
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‘Leptorapide’ – a one-step assay for rapid diagnosis of human leptospirosis
- T. BROWNLOW, O. V. KAVANAGH, E. F. LOGAN, R. A. HARTSKEERL, R. SAVAGE, M. F. PALMER, M. KRAHL, D. P. MACKIE, W. A. ELLIS
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- Epidemiology & Infection / Volume 142 / Issue 6 / June 2014
- Published online by Cambridge University Press:
- 19 September 2013, pp. 1182-1187
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Leptospirosis is a globally important zoonotic infection caused by spirochaetes of the genus Leptospira. It is transmitted to humans by direct contact with infected animals or indirectly via contaminated water. It is mainly a problem of the resource-poor developing countries of the tropical and sub-tropical regions of the world but outbreaks due to an increase in travel and recreational activities have been reported in developed and more industrialized areas of the world. Current methods of diagnosis are costly, time-consuming and require the use of specialized laboratory equipment and personnel. The purpose of this paper is to report the validation of the ‘Leptorapide®’ test (Linnodee Ltd, Northern Ireland) for the diagnosis of human leptospirosis. It is a simple one-step latex agglutination assay performed using equal volumes of serum sample and antigen-bound latex beads. Evidence of leptospiral antibodies is determined within minutes. Agglutination is scored on a scale of 1–5 and the results interpreted using a score card provided with the kit. Validation has been performed with a large sample size obtained from individuals originating from various parts of the world including Brazil and India. The test has shown sensitivity and specificity values of 97·1% and 94·0%, respectively, relative to the microscopic agglutination test. The results demonstrate that Leptorapide offers a cost-effective and accurate alternative to the more historical methods of antibody detection.
Microbiological and chemical changes in the rumen during the stepwise adaptation of sheep to high concentrate diets
- R. I. Mackie, Frances M. C. Gilchrist, Anna M. Robberts, P. E. Hannah, Helen M. Schwartz
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- The Journal of Agricultural Science / Volume 90 / Issue 2 / April 1978
- Published online by Cambridge University Press:
- 27 March 2009, pp. 241-254
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A stepwise adaptation was carried out on eight sheep through diets containing 10, 24, 44, 60 to a final diet containing 71% maize meal and molasses. The numbers of protozoa in the rumen increased in proportion to amount of readily fermentable carbohydrate fed, up to and including the 60% grain and molasses diet, while the numbers of total culturable bacteria remained essentially constant. However, the proportions of amylolytic and lactate-utilizing bacteria increased, and there was an orderly shift from acid-sensitive to more acid-tolerant species, particularly amongst the lactate-utilizers in response to the gradual decrease in the ruminal pH. Up to this stage the protozoa probably controlled the rate of fermentation by engulfing starch grains and bacteria and were thus able to maintain the pH of the rumen above 5·5. Lactic acid appeared only transiently and the peak values tended to diminish as adptation progressed.
The first day the final diet was fed the ruminal pH decreased to 5·4 or below for several hours. Within 7 days the number of protozoa had decreased by 50–80% and the number of total culturable bacteria increased sharply. Conditions in the rumen became unstable: peak values of D- and L- laotic acid increased by ca. 0·5 HIM, the acetate/propionate ratio decreased to ca. 2 and peak glucose concentration increased t o 3·2–9·5 mM. One animal refused all food for 1 day. Acid-tolerant species of lactate-utilizing bacteria multiplied rapidly in response to the increased production of ruminal lactic acid and the ratio of amylolytics to lactate-utilizers decreased from a mean of 10·7 to 3·6. This controlled the increase in lactic acid and the decrease in ruminal pH, allowing the ciliate protozoa to proliferate and regain control of the fermentation.
The types of cellulolytic bacteria did not change during the experiment. Despite their acid sensitivity, the number of cellulolytic bacteria per gram of ingesta was of the same order after 54 days on the 71% grain and molasses diet (0·5–13·3 × 107) as on the initial high roughage diet (3·2–7·6 × 107).
Three sheep which bloated showed no marked chemical or microbiological differences from the non-bloating animals.
Utilization of fish protein hydrolysates in milk substitutes for lambs
- H. S. Soliman, E. R. Ørskov, I. Mackie
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- Journal:
- The Journal of Agricultural Science / Volume 93 / Issue 1 / August 1979
- Published online by Cambridge University Press:
- 27 March 2009, pp. 37-46
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Male and female (Suffolk × (Finnish Landraee × Dorset Horn)) lambs were used in three experiments to examine the replacement of milk by undried and dried fish protein hydrolysates (FPH), a mixture of lard and coconut fat, and partially hydrolysed starch (Protamyl 110). The animals received the experimental diets from 1 week of age in Expts 1 and 2, and from 4 weeks of age in Expt 3. They were given the diets in eight equal feeds (i.e. every 3 h) from an automated teat bar system. The level of feeding was 1·046 MJ/kg0−76/day. Experiments 1 and 2 lasted for 35 days, during which live-weight gain and food conversion ratios were recorded and at the end the digestibility of N, dry matter and starch was determined. Experiment 3 consisted of three small digestibility trials.
In Expt 1, the replacement of milk protein with undried FPH and of milk fat with lard plus coconut fat had no significant effects on live-weight gain, food conversion ratio or nutrient digestibility. Somewhat lower gains for the lambs given the FPH than those given milk protein were observed during the first 15 days of the experiment. Apparent digestibility of milk protein and milk fat was 95 and 99% while that of PFH and lard plus coconut fat was 94 and 96% respectively. The replacement of milk fat with lard and coconut fat caused some reduction in live-weight gains and nutrient digestibility. Lactose was completely replaced by protamyl both in diets based on milk protein or FPH with no effect on live-weight gains or food conversion ratio.
Apparent digestibility of fish protein was not affected by the drying process. Fat digestibility of diets containing undried or dried FPH ranged from 46 to 98% according to the type of emulsifier used. The results are discussed in relation to published data concerning the problems associated with the use of fish protein in milk replacers.
A comparison of undried and dried fish-protein hydrolysate as a protein source for calf milk replacers
- A. M. Petchey, J. B. Owen, I. M. Mackie, A. H. Ritchie, E. R. Ørskov
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- Journal:
- Animal Production / Volume 28 / Issue 2 / April 1979
- Published online by Cambridge University Press:
- 02 September 2010, pp. 191-198
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- April 1979
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Milk replacers in which skim milk protein (SMP) was replaced in various proportions by undried or dried fish protein hydrolysate (FPH) were offered twice daily to British Friesian male calves. Various proportions of fish protein and milk protein in the diets were obtained by mixing replacer made from SMP with replacers made from undried and dried FPH respectively. The ratios were: 100 FPH, 0 SMP; 67 FPH, 33 SMP; 33 FPH, 67 SMP; and 0 FPH, 100 SMP. Calves were offered the milk replacers only to a maximum of 5 1 per day until 28 days when concentrates and hay were offered ad libitum. The calves were weaned after 42 days. Feed intake and live-weight gain were recorded for 84 days.
There was a marked decrease in performance to weaning when the milk replacer contained two-thirds or more of the FPH. The FPH-fed calves had lower hay intakes than those fed milk only. Treatment differences in post-weaning live-weight gain reflected mainly differences in concentrate intake. There was no significant difference in live-weight gain nor food efficiency for calves fed either undried or dried FPH in any period to 84 days. The number of treatments for scour was similar for the two groups. However, the calves fed dried FPH had a lower dry-matter intake in the post-weaning period.
Fish-protein hydrolysate as a substitute for milk protein in calf feeding
- T. L. Dodsworth, J. B. Owen, I. M. Mackie, A. Ritchie, E. R. Ørskov
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- Journal:
- Animal Production / Volume 25 / Issue 1 / August 1977
- Published online by Cambridge University Press:
- 02 September 2010, pp. 19-26
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- August 1977
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Two milk replacers identical in composition except for the protein source, which was either fish-protein hydrolysate (FPH) or dried skim milk, were offered either twice or four times daily to castrated British Friesian male calves in four ratios: 100 FPH 0 Milk; 67 FPH 33 Milk; 33 FPH 67 Milk and 0 FPH 100 Milk. Concentrates and hay were offered ad libitum, and the calves were weaned at 42 days of age. Feed intake and calf live weight were recorded to 100 days of age.
There were no differences in growth rate up to weaning due to frequency of feeding. Up to 67% FPH there were no differences in growth rate but calves on the 100% FPH diet showed a 40% depression in growth compared with the other three levels. Up to 100 days there was no apparent effect of treatment on live-weight gain, but only differences of 12 to 13% would be significant.
The results indicate that at least two-thirds of the milk protein could be replaced by FPH. The need for further work using dried material and FPH from other species is discussed.
Training in Psychotherapy: The Aberdeen Diploma Course
- W. M. Millar, R. E. Mackie, J. D. Gomersall
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- Journal:
- The British Journal of Psychiatry / Volume 114 / Issue 516 / November 1968
- Published online by Cambridge University Press:
- 29 January 2018, pp. 1425-1428
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- November 1968
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In recent years British psychiatric training has received interested scrutiny from the other side of the Atlantic, and there has been appreciation of the broad based approach in dealing with the larger community of psychiatric patients, which as Keir (1964) has pointed out is beginning to occupy the attention of our American colleagues. It has been noted by Cameron (1965), Lesse (1966) and others that there are disadvantages in the predominant approach in American training—which focuses on dynamics, inference and formulation—in that this has produced a neglect of clinical observation and accurate description, giving little knowledge of syndromes or the natural history of psychiatric conditions.
The Journal and its Contents
- R. E. Mackie
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- Journal:
- The British Journal of Psychiatry / Volume 113 / Issue 504 / November 1967
- Published online by Cambridge University Press:
- 29 January 2018, p. 1317
- Print publication:
- November 1967
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