2 results
The improvement of healthy habits in patients with severe mental disorders: the LIFESTYLE trial
- V. Sollo, M. Di Vincenzo, M. Carbone, A. Rosa, R. Toricco, L. Tretola, M. Luciano, G. Sampogna, A. Fiorillo
-
- Journal:
- European Psychiatry / Volume 66 / Issue S1 / March 2023
- Published online by Cambridge University Press:
- 19 July 2023, pp. S74-S75
-
- Article
-
- You have access Access
- Open access
- Export citation
-
Introduction
The impact of unhealthy lifestyle behaviors is significant in the general population, being associated with chronic physical conditions, reduced life expectancy and increased healthcare costs. This impact is higher in patients with severe mental disorders (SMD). In fact, SMD patients present higher rates of obesity, metabolic syndrome, diabetes, and cardiovascular diseases compared to the general population. The relationship between physical and mental health is multifactorial and includes side effects of many psychotropic drugs, sedentary behaviors, reduction of physical exercise, smoking, and substance abuse. Finally, illness-related factors, including cognitive impairment, reduced psychosocial functioning, social isolation, and self-stigma, can significantly impact on patients’ physical health.
ObjectivesThis study, coordinated by the Department of Psychiatry of the University of Campania “L. Vanvitelli”, aims to test the efficacy of a lifestyle group intervention, compared to a brief psycho-educational intervention, in improving healthy habits in a real-world sample of patients with SMD.
Methods401 patients were recruited and randomly allocated to receive the experimental or the control intervention. Inclusion criteria were age between 18 and 65 years; primary diagnosis of schizophrenia, schizoaffective disorder, delusional disorder, other psychotic disorders, major depressive disorder, or bipolar disorder according to the DSM-5; BMI≥ 25. At baseline and 6 months post-randomization all patients were administered: SCID-5, BPRS, MATRICS, MCCB, IPAQ and a questionnaire on lifestyle behaviors developed by the Italian National Institute of Health.
Results206 patients were allocated to the experimental group and 195 in the control one, of which 43.3% had a main diagnosis of bipolar disorder, 29.9% of psychosis and 26.9% of major depression. Patients were mainly female (57%), with a mean age of 45.6±11.8 years and with an educational level of 11.7±2.9 years. All patients were treated with at least one psychotropic drug. About 29.4% of patients reported performing physical activity regularly, while only 3.7% performed at least 75 min of vigorous physical activity per week. Patients practicing physical activity report higher levels of perceived satisfaction with the quality of life compared with non-active patients (p < 0.005). A general improvement in dietary patterns from T0 to T1 was found in patients receiving the experimental intervention. We found an increased weekly intake of fish (p < .001), vegetables (p < .05) and fresh fruit (p < .01). Moreover, we also found a reduction of junk food (p <.05) and of weekly consumption of cereals (p < .01).
ConclusionsOur findings show that patients with SMD can improve their lifestyle behaviors with appropriate support. There is the need to implement similar interventions clinical practice to reduce the mortality gap in patients with SMD.
Disclosure of InterestNone Declared
Turbulence laws in natural bed flows
- Domenico Ferraro, Sergio Servidio, Vincenzo Carbone, Subhasish Dey, Roberto Gaudio
-
- Journal:
- Journal of Fluid Mechanics / Volume 798 / 10 July 2016
- Published online by Cambridge University Press:
- 06 June 2016, pp. 540-571
-
- Article
- Export citation
-
Characterization of turbulence in natural bed streams is one of the most fascinating problems of fluid dynamics. In this study, a statistical description of turbulence in a natural pebble bed flow is presented applying the laws of turbulence. A laboratory experiment was conducted to measure the three-dimensional instantaneous velocity components in a flow over heterogeneous coarse sediments that simulated a natural bed. The analysis reveals that the spectra (in Fourier space) show a power-law scaling,
$E(k)\sim k^{{\it\alpha}}$, suggesting the presence of inertial range turbulence. The exponent
${\it\alpha}$ is slightly shallower than the Kolmogorov
$5/3$ scaling law, with this deviation possibly due to the bed roughness heterogeneity and to fluctuation anisotropy. The Taylor frozen-in approximation is broken at smaller scales towards the roughness crest level; therefore, a new statistical tool for the validation of this approximation is proposed. The Kolmogorov
$4/5$-law for the longitudinal increments and simultaneously the Monin–Yaglom
$4/3$-law for the nonlinear normal fluxes (both in physical space) are preserved, providing an accurate estimation of the turbulent kinetic energy dissipation rate. The heterogeneity of the bed acts to induce the transport of finite kinetic helicity to the outer layer through persistently prolonged vortices. An associated
$2/15$-law for the cascade of helicity has been locally found. These findings open a new direction in turbulence research for flows over highly rough beds.
![](/core/cambridge-core/public/images/lazy-loader.gif)