We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
To send content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to .
To send content items to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Find out more about the Kindle Personal Document Service.
Though not the first attempt to ameliorate a human genetic disease by modifying somatic cells, the experiments performed by Dr. Martin J. Cline on two women suffering from thalassemia (one in Jerusalem, the other in Naples) were the first and still the only ones to use rDNA techniques.1 In some respects the criticism and censure of Cline by the NIH resembles the case of Dr. Ian T. Kennedy.2 Both Cline and Kennedy were found guilty of having violated the NIH Guidelines for Research Involving Recombinant DNA Molecules, but there is a crucial difference between the two cases. Cline attempted to implant genetically altered cells into human beings. Consequently, his work involved moral issues concerning the use of human subjects in biomedical experiments which go beyond the usual concerns over safety and control in rDNA research. In fact, I shall argue that the rDNA aspect of the Cline affair was relatively minor compared with the moral reasoning which guided the actions and judgments of Cline and his critics. Despite its importance for understanding the behavior of the participants, this ethical dimension does not receive adequate emphasis in Robin and Markle's account of the Cline episode within the framework of their four sociological perspectives (substantive, network, organizational, societal).
Email your librarian or administrator to recommend adding this to your organisation's collection.