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This article examines the significance of a highly unusual stone statue discovered at Teynham, Kent, depicting a triton and a ketos. It discusses the context of the find in what appears to be a mausoleum complex adjacent to Watling Street. It provides a detailed description of the statue itself, alongside a petrological study, and places this in the context of other depictions of marine deities, particularly of tritons, in Britain and beyond. The article considers how the sculpture might have been placed on the exterior or interior of the tomb. It also discusses the possible occupant of the mausoleum (perhaps a villa owner or sailor), taking into account the possible symbolic value of the triton, either as signifier of afterlife beliefs or biographical achievement, as well as the ritual treatment of the statue after the tomb was dismantled. The wider context of the Teynham mausoleum is then analysed in terms of its location and form in relation to comparable monuments found in south-east England and better preserved tombs on the continent.
We present the third data release from the Parkes Pulsar Timing Array (PPTA) project. The release contains observations of 32 pulsars obtained using the 64-m Parkes ‘Murriyang’ radio telescope. The data span is up to 18 yr with a typical cadence of 3 weeks. This data release is formed by combining an updated version of our second data release with $\sim$3 yr of more recent data primarily obtained using an ultra-wide-bandwidth receiver system that operates between 704 and 4032 MHz. We provide calibrated pulse profiles, flux density dynamic spectra, pulse times of arrival, and initial pulsar timing models. We describe methods for processing such wide-bandwidth observations and compare this data release with our previous release.
Beaded rims are a characteristic feature of late Roman silver plate vessels, many of which have been found in British treasures including Mildenhall and Traprain Law. This paper discusses how these beaded rims provide insights into the production of silver plate, adding to what little is known of silver plate workshops. Vessels in the Mildenhall treasure provide a case study, after which measurements from beaded rims on other treasures from Roman Britain and the western Roman Empire are compared and discussed.
Coronavirus disease 2019 (COVID-19) has disproportionately affected people with mental health conditions.
Aims
We investigated the association between receiving psychotropic drugs, as an indicator of mental health conditions, and COVID-19 vaccine uptake.
Method
We conducted a cross-sectional analysis of a prospective cohort of the Northern Ireland adult population using national linked primary care registration, vaccination, secondary care and pharmacy dispensing data. Univariable and multivariable logistic regression analyses investigated the association between anxiolytic, antidepressant, antipsychotic, and hypnotic use and COVID-19 vaccination status, accounting for age, gender, deprivation and comorbidities. Receiving any COVID-19 vaccine was the primary outcome.
Results
There were 1 433 814 individuals, of whom 1 166 917 received a COVID-19 vaccination. Psychotropic medications were dispensed to 267 049 people. In univariable analysis, people who received any psychotropic medication had greater odds of receiving COVID-19 vaccination: odds ratio (OR) = 1.42 (95% CI 1.41–1.44). However, after adjustment, psychotropic medication use was associated with reduced odds of vaccination (ORadj = 0.90, 95% CI 0.89–0.91). People who received anxiolytics (ORadj = 0.63, 95% CI 0.61–0.65), antipsychotics (ORadj = 0.75, 95% CI 0.73–0.78) and hypnotics (ORadj = 0.90, 95% CI 0.87–0.93) had reduced odds of being vaccinated. Antidepressant use was not associated with vaccination (ORadj = 1.02, 95% CI 1.00–1.03).
Conclusions
We found significantly lower odds of vaccination in people who were receiving treatment with anxiolytic and antipsychotic medications. There is an urgent need for evidence-based, tailored vaccine support for people with mental health conditions.
We describe 14 yr of public data from the Parkes Pulsar Timing Array (PPTA), an ongoing project that is producing precise measurements of pulse times of arrival from 26 millisecond pulsars using the 64-m Parkes radio telescope with a cadence of approximately 3 weeks in three observing bands. A comprehensive description of the pulsar observing systems employed at the telescope since 2004 is provided, including the calibration methodology and an analysis of the stability of system components. We attempt to provide full accounting of the reduction from the raw measured Stokes parameters to pulse times of arrival to aid third parties in reproducing our results. This conversion is encapsulated in a processing pipeline designed to track provenance. Our data products include pulse times of arrival for each of the pulsars along with an initial set of pulsar parameters and noise models. The calibrated pulse profiles and timing template profiles are also available. These data represent almost 21 000 h of recorded data spanning over 14 yr. After accounting for processes that induce time-correlated noise, 22 of the pulsars have weighted root-mean-square timing residuals of
$<\!\!1\,\mu\text{s}$
in at least one radio band. The data should allow end users to quickly undertake their own gravitational wave analyses, for example, without having to understand the intricacies of pulsar polarisation calibration or attain a mastery of radio frequency interference mitigation as is required when analysing raw data files.
We describe an ultra-wide-bandwidth, low-frequency receiver recently installed on the Parkes radio telescope. The receiver system provides continuous frequency coverage from 704 to 4032 MHz. For much of the band (
${\sim}60\%$
), the system temperature is approximately 22 K and the receiver system remains in a linear regime even in the presence of strong mobile phone transmissions. We discuss the scientific and technical aspects of the new receiver, including its astronomical objectives, as well as the feed, receiver, digitiser, and signal processor design. We describe the pipeline routines that form the archive-ready data products and how those data files can be accessed from the archives. The system performance is quantified, including the system noise and linearity, beam shape, antenna efficiency, polarisation calibration, and timing stability.
Thomas Hobbes' Leviathan is arguably the greatest piece of political philosophy written in the English language. Written in a time of great political turmoil (Hobbes' life spanned the reign of Charles I, the Civil Wars, the Commonwealth and the Protectorate, and the Restoration), Leviathan is an argument for obedience to authority grounded in an analysis of human nature. Since its first publication in 1991 Richard Tuck's edition of Leviathan has been recognised as the single most accurate and authoritative text, and for this revised edition Professor Tuck has provided a much amplified and expanded introduction, which will provide students unfamiliar with Hobbes with a cogent and accessible introduction to this most challenging of texts. Other vital aids to study include an extensive guide to further reading, a note on textual matters, a chronology of important events and brief biographies of important persons mentioned in Hobbes' text.
De Cive (On the Citizen) is the first full exposition of the political thought of Thomas Hobbes, the greatest English political philosopher of all time. Professors Tuck and Silverthorne have undertaken the first complete translation since 1651, a rendition long thought (in error) to be at least sanctioned by Hobbes himself. On the Citizen is written in a clear, straightforward, expository style, and in many ways offers students a more digestible account of Hobbes's political thought than the Leviathan itself. This new translation is both accurate and accessible, and is itself a significant scholarly event: it is accompanied by a full glossary of Latin terms, a chronology, bibliography, and an expository introduction. Throughout the editors have emphasised consistency in the translation and usage of Hobbes's basic conceptual vocabulary, respecting Hobbes's own concern for accurate definition of terms.
The hoard of silver plate known as the Vinkovci treasure (or the Cibalae treasure, after the Roman name for the town) was discovered on March 23, 2012, during rescue excavations in the town of Vinkovci (Colonia Aurelia Cibalae) in the Vukovar-Srijem county of E Croatia (fig. 1). It is one of the most significant late Roman discoveries of the new millennium, and the first major 4th-c. A.D. assemblage of silver plate to be unearthed for at least half a century (the Seuso treasure was probably found in the late 1970s, and although new pieces of the Kaiseraugst treasure emerged in the 1990s the original discovery was made in 1961). This interim report on the treasure is based upon the results of research conducted by the authors in the 4 years that have passed since it came to light.
Subclinical hypothyroidism (SCHo) is a common biochemical diagnosis in older age. Evidence of impact is inconclusive and guidelines are inconsistent. With increasing numbers of thyroid function tests (TFTs) performed, GPs frequently have to make management decisions regarding this diagnosis. However, little is known about how SCHo is currently being managed in primary care.
Aim
To explore management of SCHo in primary care and GP reported rationale for treatment of SCHo in older individuals.
Design
Descriptive study using retrospective case note review and GP survey.
Setting
Nineteen General Practices, Central England, UK.
Methods
Follow-up of a large cohort with subsequent detailed review of individuals for whom therapy had been initiated following diagnosis of SCHo. Data on practice policies, and rationale behind treatment were collected via GP questionnaire.
Results
Forty-two individuals were treated following identification of SCHo. Factors regarded as supporting instigation of therapy recorded by practitioners included symptoms, a positive antithyroid antibody test and history of radioiodine therapy. In all, 55% were registered at 3/19 practices suggesting significant between practice variation. Reasons for testing included chronic disease check-up (n = 14), presenting ‘thyroid symptoms’ (n = 5) and presenting other symptoms (n = 9). Reasons for therapy initiation were only recorded in 26 cases and included presence of symptoms, persistently high or increasing serum thyroid stimulating hormone concentration and patient request. Only 2/15 GPs reported having practice guidelines on management.
Conclusion
Results suggest that GPs are uncertain how to interpret symptoms and TFT results in older individuals. There is considerable variation in management of SCHo between GPs with some GPs treating patients outside of all guideline recommendations.
An Ensemble Pulsar Time Scale (EPT) is derived based on the Pulsar Timing Array. It is interesting to compare the EPT with the TT terrestrial time scale, and get many new realization on the pulsar time scale and the algorithm. Some future interesting applications of the EPT are described and discussed.
A strain of the alfalfa leafcutter bee, Megachile pacifica Panzer, that has produced less than 1% second-generation adults for 3 consecutive years was produced by selection against bivoltinism. The selection process also resulted in the production of bees that reproduced at a much higher rate than the unselected parent stock.
The ‘William Allen box’ is a rare survival of a collection of antiquities, mostly of Roman date, collected in the Victorian period. This paper discusses the identity and life of the collector and some of the more notable objects before examining the provenance of some of the material, in particular the findspots ‘Ad Fines’ and ‘Croydon’. The importance of the collection in the context of the antiquarian age in which it was assembled is also discussed.
During the 1950s a number of Birmingham practices began to offer an informal experience of general practice to students in their elective period. Some offered contacts in the evenings or at weekends to students who requested this. The Birmingham LMC was active in encouraging such experiences. In 1966 the Midland faculty of the then College of General Practitioners began to explore the possibility of establishing a formal post in the medical school and Michael Drury, who had recently returned from a Nuffield Fellowship, was offered a part-time post as a lecturer in the department of social medicine by Professor Thomas McKeown. This enabled these elective attachments to be promoted more formally and with clear objectives and assessments.
These became sufficiently well taken up for the Dean, a neurosurgeon Professor Brodie Hughes, to agree that if outside money could be found for four years a part-time post with secretarial help would be established. Money was raised, principally thanks to the activities of two members of the faculty board, Micky Dale and Robin Steel, partly from a private donation and partly from a voluntary levy introduced by all the LMCs in the area. This enabled an appointment committee to be established in 1974 and Michael Drury was duly appointed Clarkson (named after the private donor) senior clinical tutor on a half-time basis. There was considerable discussion about where this post should be based.
This book was first published in 2006. Despite many well-intentioned policies and changes to management practices, the world's natural resources continue to decline. The roles and interplay between science and policy in the regional broadacre agriculture landscape are examined here, offering readers a thorough understanding of the complex interactions that occur across spatial scales to produce the regional-scale impacts. The fundamental causes of resource degradation, social decline and environmental pollution are addressed, examining the cross-scale drivers from the individual farm level to the global level of commodity systems. Broadacre agriculture is a common land use throughout all continents of the world and is driven by the same type of dynamics, and this case study of the Western Australia agricultural region can be used to clearly demonstrate the principles for other agricultural systems. Aimed at academics, ranging from researchers through to policy analysts, this book will inspire innovation and action in sustainable natural resource management.
Landscape ecology is a relatively new area of study, which aims to understand the pattern of interaction of biological and cultural communities within a landscape. This book brings together leading figures from the field to provide an up-to-date survey of recent advances, identify key research problems and suggest a future direction for development and expansion of knowledge. Providing in-depth reviews of the principles and methods for understanding landscape patterns and changes, the book illustrates concepts with examples of innovative applications from different parts of the world. Forming a current 'state-of-the-science' for the science of landscape ecology, this book forms an essential reference for graduate students, academics, professionals and practitioners in ecology, environmental science, natural resource management, and landscape planning and design.