Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-76fb5796d-25wd4 Total loading time: 0 Render date: 2024-04-30T03:40:59.568Z Has data issue: false hasContentIssue false

Chapter 7 - Pharmacology of histamine, muscarine and dopamine antagonists

Published online by Cambridge University Press:  05 March 2016

By
Tricia A. Meyer  and
Russell K. McAllister
Edited by
Tong Joo Gan  and
Ashraf S. Habib
Foreword by
Henrik Kehlet
Tong Joo Gan
Affiliation:
Duke University Medical Center, Durham
Ashraf S. Habib
Affiliation:
Duke University Medical Center, Durham
Get access

Summary

A summary is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Chapter
Information
Postoperative Nausea and Vomiting
A Practical Guide
 , pp. 62 - 73
Publisher: Cambridge University Press
Print publication year: 2016

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Kovac, A. Prevention and treatment of postoperative nausea and vomiting. Drugs 2000; 59: 213–43.CrossRefGoogle ScholarPubMed
Golembiewski, J, Tokumara, S. Pharmacological prophylaxis and management of adult postoperative/postdischarge nausea and vomiting. J Perianesth Nurs 2006; 21: 385–97.CrossRefGoogle ScholarPubMed
McEvoy, GK, Snow, ED, eds. AHFS: Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 2013; 1–14.Google Scholar
Kluwer, Wolters. Lexicomp Online: Dimenhydrinate, 2014. http://online.lexi.com/lco/action/search?q=dimenhydrinate&t=name. (Accessed October 25, 2014.)Google Scholar
Kluwer, Wolters. Lexicomp Online: Diphenhydramine. 2014. http://online.lexi.com/lco/action/search?q=diphenhydramine&t=name. (Accessed October 25, 2014.)Google Scholar
Kluwer, Wolters. Lexicomp Online: Meclizine, 2014 http://online.lexi.com/lco/action/search?q=meclizine&t=name. (Accessed October 25, 2014.)Google Scholar
Kluwer, Wolters. Lexicomp Online: Hydroxyzine, 2014. http://online.lexi.com/lco/action/search?q=hydroxyzine&t=name. (Accessed October 25, 2014.)Google Scholar
Kluwer, Wolters. Lexicomp Online: Cyclizine, 2014. http://online.lexi.com/lco/action/search?q=cyclizine&t=name. (Accessed October 25, 2014.)Google Scholar
Kluwer, Wolters. Lexicomp Online: Promethazine, 2014. http://online.lexi.com/lco/action/search?q=promethazine&t=name. (Accessed October 25, 2014.)Google Scholar
Gan, TJ, Diemunsch, P, Habib, A, et al. Consensus guidelines for the management of postoperative nausea and vomiting. Anesth Analg 2014; 118: 85–113.CrossRefGoogle ScholarPubMed
McEvoy, GK, Snow, ED, eds. AHFS: Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 2013; 2942–5.Google Scholar
Eberhart, LH, Seeling, W, Bopp, TI, et al. Dimenhydrinate for prevention of post-operative nausea and vomiting in female in-patients. Eur J Anaesthesiol 1999; 16: 284–9.CrossRefGoogle ScholarPubMed
Kothari, SN, Boyd, WC, Bottcher, ML, et al. Antiemetic efficacy of prophylactic dimenhydrinate (Dramamine) vs. ondansetron (Zofran): a randomized, prospective trial inpatients undergoing laparoscopic cholecystectomy. Surg Endosc 2000; 14: 926–9.CrossRefGoogle ScholarPubMed
Eberhart, LH, Seeling, W, Ulrich, B, et al. Dimenhydrinate and metoclopramide alone or in combination for prophylaxis of PONV. J Clin Anesth 2000; 47: 780–5.Google ScholarPubMed
Habib, A, Gan, TJ. The effectiveness of rescue antiemetics after failure of prophylaxis with ondansetron or droperidol: a preliminary report. J Clin Anesth 2005; 17: 62–5.CrossRefGoogle ScholarPubMed
Kranke, P, Morin, AM, Roewer, N, et al. Dimenhydrinate for prophylaxis of postoperative nausea and vomiting: a meta-analysis of randomized controlled trials. Acta Anaesthesiol Scand 2002; 46: 238–44.CrossRefGoogle ScholarPubMed
Lu, CW, Jean, WH, Wu, CC, et al. Antiemetic efficacy of metoclopramide and diphenhydramine added to patient-controlled morphine analgesia: a randomised controlled trial. Eur J Anaesthesiol 2010; 27: 1052–7.CrossRefGoogle ScholarPubMed
Priesol, AJ, Deschler, DG, Park, L. Motion sickness. http://www.uptodate.com/contents/search?source=USER_PREF&search (Accessed October 27, 2014.)Google Scholar
Forrester, CM, Benfield, DA, Matern, CE, et al. Meclizine in combination with ondansetron for prevention of postoperative nausea and vomiting in high risk population. AANA 2007; 75: 27–33.Google ScholarPubMed
McKenzie, R, Wadhwa, RK, Uy, NT, et al. Antiemetic effectiveness of intramuscular hydroxyzine compare with intramuscular droperidol. Anesth Analg 1981; 60: 783–8.CrossRefGoogle Scholar
Grimsehl, K, Whiteside, JB, Mackenzie, N. Comparison of cyclizine and ondansetron for the prevention of postoperative nausea and vomiting in laparoscopic day-case gynaecological surgery. Anaesthesia 2002: 57: 61–5.CrossRefGoogle ScholarPubMed
O’Brien, CM, Titley, G, Whitehouse, P. A comparison of cylcizine, ondansetron and placebo as prophylaxis against postoperative nausea and vomiting in children. Anaesthesia 2003; 58: 707–11.Google ScholarPubMed
Carlisle, J, Stevenson, CA. Drugs for preventing postoperative nausea and vomiting. Cochrane Database Syst Rev 2006; 19: CD004125.Google Scholar
McEvoy, GK, Snow, ED (eds). AHFS: Drug Information. Bethesda, MD: American Society of Health-System Pharmacists; 2013: 2528–45.Google Scholar
Kluwer, Wolters. Lexicomp Online: Prochlorperazine, 2014. http://online.lexi.com/lco/action/search?t=name&q=Prochlorperazine (Accessed October 25, 2014.)Google Scholar
Kluwer, Wolters. Lexicomp Online: Perphenazine, 2014. http://online.lexi.com/lco/action/search?t=name&q=Perphenazine. (Accessed October 25, 2014.)Google Scholar
McEvoy, GK, Snow, ED, (eds). AHFS: Drug Information. Bethesda, MD, American Society of Health-System Pharmacists, 2013; 2631–3.Google Scholar
Habib, AS, Reuveni, J, Taguchi, A, et al. A comparison of ondansetron with promethazine for treating postoperative nausea and vomiting in patients who received prophylaxis with ondansetron: a retrospective database analysis. Anesth Analg 2007; 104: 548–51.CrossRefGoogle ScholarPubMed
US Food and Drug Administration. Information for Healthcare Professionals: Intravenous Promethazine and Severe Tissue Injury, Including Gangrene. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/ucm182169.htm# (Accessed November 4, 2014.)Google Scholar
Khalil, S, Philbrook, L, Rabb, M, et al. Ondansetron/promethazine combination or promethazine for the prevention alone reduces nausea and vomiting after middle ear surgery. J Clin Anesth 1999; 11: 596–600.CrossRefGoogle ScholarPubMed
Schnabel, A, Eberhart, LH, Muellenbach, R, et al. Efficacy of perphenazine to prevent postoperative nausea and vomiting: a quantitative systematic review. Eur J Anesthesiol 2010; 27: 1044–51.CrossRefGoogle ScholarPubMed
Chen, JJ, Frame, DG, White, TJ. Efficacy of ondansetron and prochlorperazine for the prevention of postoperative nausea and vomiting after total hip replacement or total knee replacement procedures: a randomized, double-blind, comparative trial. Arch Intern Med 1998; 158: 2124–8.CrossRefGoogle ScholarPubMed
Kluwer, Wolters. Lexicomp Online: Droperidol, 2014. http://online.lexi.com/lco/action/search?q=droperidol&t=name. (Accessed October 25, 2014.)Google Scholar
Apfel, CC, Korttila, K, Abdalla, M, et al. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. N Engl J Med 2004; 350: 2441–51.CrossRefGoogle ScholarPubMed
Henzi, I, Sonderegger, J, Tramèr, MR. Efficacy, dose–response, and adverse effects of droperidol for prevention of postoperative nausea and vomiting. Can J Anaesth 2000; 47: 537–51.CrossRefGoogle ScholarPubMed
Chan, MT, Choi, KC, Gin, T, et al. The additive interactions between ondansetron and droperidol for preventing postoperative nausea and vomiting. Anesth Analg 2006; 103: 1155–62.CrossRefGoogle ScholarPubMed
Schaub, I, Lysakowski, C, Elia, N, et al. Low-dose droperidol (≤1 mg or ≤15 μg kg-1) for the prevention of postoperative nausea and vomiting in adults: quantitative systematic review of randomised controlled trials. Eur J Anaesthesiol 2012; 29(6): 286–94.CrossRefGoogle ScholarPubMed
Charbit, B, Albaladejo, P, Funck-Brentano, C, et al. Prolongation of QTc interval after postoperative nausea and vomiting treatment by droperidol or ondansetron. Anesthesiology 2005; 102: 1094–100.CrossRefGoogle ScholarPubMed
White, PF, Song, D, Abrao, J, et al. Effect of low-dose droperidol on the QT interval during and after general anesthesia: a placebo-controlled study. Anesthesiology 2005; 102: 1101–5.CrossRefGoogle Scholar
Nuttall, GA, Malone, AM, Michels, CA, et al. Does low-dose droperidol increase the risk of polymorphic ventricular tachycardia or death in the surgical patient? Anesthesiology 2013; 118: 382–6.CrossRefGoogle ScholarPubMed
Kluwer, Wolters. Lexicomp Online: Haloperidol, 2014. http://online.lexi.com/lco/action/search?q=haloperidol&t=name. (Accessed October 25, 2014.)Google Scholar
Büttner, M, Walder, B, von Elm, E, et al. Is low-dose haloperidol a useful antiemetic?: A meta-analysis of published and unpublished randomized trials. Anesthesiology 2004; 101: 1454–63.CrossRefGoogle ScholarPubMed
Aouad, MT, Siddik-Sayyid, SM, Taha, SK, et al. Haloperidol vs. ondansetron for the prevention of postoperative nausea and vomiting following gynaecological surgery. Eur J Anaesthesiol 2007; 24: 171–8.CrossRefGoogle ScholarPubMed
Wang, TF, Liu, YH, Chu, CC, et al. Low-dose haloperidol prevents post-operative nausea and vomiting after ambulatory laparoscopic surgery. Acta Anaesthesiol Scand 2008; 52: 280–4.CrossRefGoogle ScholarPubMed
Rosow, CE, Haspel, KL, Smith, SE, et al. Haloperidol versus ondansetron for prophylaxis of postoperative nausea and vomiting. Anesth Analg 2008; 106: 1407–9.CrossRefGoogle ScholarPubMed
Feng, PH, Chu, KS, Lu, IC, et al. Haloperidol plus ondansetron prevents postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. Acta Anaesthesiol Taiwan 2009; 47(1): 3–9.CrossRefGoogle ScholarPubMed
Kluwer, Wolters. Lexicomp Online: Metoclopramide. 2014. http://online.lexi.com/lco/action/search?q=metocl&t=name. (Accessed October 25, 2014.)Google Scholar
Henzi, I, Walder, B, Tramèr, MR. Metoclopramide in the prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized, placebo-controlled studies. Br J Anaesth 1999; 83: 761–71.CrossRefGoogle ScholarPubMed
Wallenborn, J, Gelbrich, G, Bulst, D, et al. Prevention of postoperative nausea and vomiting by metoclopramide combined with dexamethasone: randomised double blind multicentre trial. BMJ 2006; 12: 324.CrossRefGoogle Scholar
Kluwer, Wolters. Lexicomp Online: Scopolamine. 2014. http://online.lexi.com/lco/action/doc/retrieve/docid/patch_f/1801741. (Accessed October 25, 2014.)Google Scholar
Bailey, PL, Streisand, JB, Pace, NL et al. Transdermal scopolamine reduces nausea and vomiting after outpatient laparoscopy. Anesthesiology 1990; 72: 977–80.CrossRefGoogle ScholarPubMed
White, PF, Tang, J, Song, D, et al. Transdermal scopolamine: an alternative to ondansetron and droperidol for the prevention of postoperative and postdischarge emetic symptoms. Anesth Analg 2007; 104: 92–6.CrossRefGoogle ScholarPubMed
Apfel, CC, Zhang, K, George, E, et al. Transdermal scopolamine for the prevention of postoperative nausea and vomiting: a systematic review and meta-analysis. Clin Ther 2010; 32: 1987–2002.CrossRefGoogle ScholarPubMed
Lee, DT, Jenkins, NL, Anastasopulos, AJ. Transdermal scopolamine and perioperative anisocoria in craniofacial surgery: a report of 3 patients. J Craniofac Surg 2013; 24: 470–2.Google ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×