In adults, a diet low in sodium and high in potassium helps reduce blood pressure and risk of cardiovascular disease(1). Whether this same relationship exists among children is less clear. There is some evidence to indicate that reducing sodium intake is favourable for maintaining healthy blood pressure levels across childhood(2). However, it is not clear how sodium intake during childhood influences blood pressure and whether sex or body mass index moderates any effects. The effects of potassium intake and the sodium-to-potassium ratio on children’s blood pressure have been generally inconsistent(3). It is important to understand the relationship between sodium and potassium on childhood blood pressure as elevated blood pressure across childhood increases the risk of future hypertension and target organ damage(4). Few studies in children have utilised the 24-hour urinary electrolyte excretion, an objective measure, of sodium intake. Therefore, this study examined the relationship between 24-hour urinary sodium, potassium and sodium-to-potassium molar ratio and blood pressure among Australian schoolchildren aged 4–12 years; and if these associations were moderated by body weight or sex. Data from 793 children who participated in the Salt and Other Nutrient Intakes in Children study were included in this analysis. Children recruited from primary schools (n = 61) located across the state of Victoria provided one 24-hour urine collection, and anthropometric and blood pressure measurements. Blood pressure z-scores standardised for age, sex and height were calculated. Multiple linear regression analysis, with adjustment for covariates (age, sex, socioeconomic position and weight category), was conducted. Body weight (underweight/healthy weight, overweight and obese) and sex subgroup analyses, including interaction terms were completed. Mean (SD) sodium excretion was 2386 (1046) (SD) mg/d and 72% of children exceeded the recommended upper level for sodium intake. Mean (SD) potassium excretion was 1796 (675) mg/d and the sodium-to-potassium molar ratio was 2.4 (1.1). Eighteen percent of children had elevated blood pressure. Overall, there were no associations between 24-hour sodium or potassium excretion and blood pressure in adjusted regression models. However, there was a significant positive association between sodium excretion and systolic blood pressure z-score in children with obesity (b-coefficient 0.70 [95% CI 0.05, 1.33], p = 0.04, n = 23) and among girls (b-coefficient 0.09 [95% CI 0.01, 0.17], p = 0.02, n = 365). We found a positive association between 24-hr urinary excretion and SBP in girls and children living with obesity, providing further support to the hypothesis that body weight is a moderator of this relationship through heightened salt sensitivity. Public health interventions aiming to reduce elevated blood pressure during childhood are likely to be most effective by reducing sodium intake in conjunction with promoting healthy weight.