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Education can be viewed as a control theory problem in which students seek ongoing exogenous input—either through traditional classroom teaching or other alternative training resources—to minimize the discrepancies between their actual and target (reference) performance levels. Using illustrative data from \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$n=784$$\end{document} Dutch elementary school students as measured using the Math Garden, a web-based computer adaptive practice and monitoring system, we simulate and evaluate the outcomes of using off-line and finite memory linear quadratic controllers with constraintsto forecast students’ optimal training durations. By integrating population standards with each student’s own latent change information, we demonstrate that adoption of the control theory-guided, person- and time-specific training dosages could yield increased training benefits at reduced costs compared to students’ actual observed training durations, and a fixed-duration training scheme. The control theory approach also outperforms a linear scheme that provides training recommendations based on observed scores under noisy and the presence of missing data. Design-related issues such as ways to determine the penalty cost of input administration and the size of the control horizon window are addressed through a series of illustrative and empirically (Math Garden) motivated simulations.
Homeless shelter residents and staff may be at higher risk of SARS-CoV-2 infection. However, SARS-CoV-2 infection estimates in this population have been reliant on cross-sectional or outbreak investigation data. We conducted routine surveillance and outbreak testing in 23 homeless shelters in King County, Washington, to estimate the occurrence of laboratory-confirmed SARS-CoV-2 infection and risk factors during 1 January 2020–31 May 2021. Symptom surveys and nasal swabs were collected for SARS-CoV-2 testing by RT-PCR for residents aged ≥3 months and staff. We collected 12,915 specimens from 2,930 unique participants. We identified 4.74 (95% CI 4.00–5.58) SARS-CoV-2 infections per 100 individuals (residents: 4.96, 95% CI 4.12–5.91; staff: 3.86, 95% CI 2.43–5.79). Most infections were asymptomatic at the time of detection (74%) and detected during routine surveillance (73%). Outbreak testing yielded higher test positivity than routine surveillance (2.7% versus 0.9%). Among those infected, residents were less likely to report symptoms than staff. Participants who were vaccinated against seasonal influenza and were current smokers had lower odds of having an infection detected. Active surveillance that includes SARS-CoV-2 testing of all persons is essential in ascertaining the true burden of SARS-CoV-2 infections among residents and staff of congregate settings.
Doyle’s (2013) theoretical survey of discount functions criticizes two parametric families abbreviated as CRDI and CADI families. We show that Doyle’s criticisms are based on a mathematical mistake and are incorrect.
Conflicts are increasingly analysed as exhibiting a stealth complexity in which triggers and consequences are intricately linked to climate, environmental degradation and the struggle to control a finite pool of natural resources. The climate crisis is a multifaceted reality and, against this background, many pressing priorities compete with each other. The disruptive effect of climate variability and change on food systems is particularly acute and constitutes a direct and tangible threat to livelihoods globally. The objective of this paper is to demonstrate and discuss the importance of food systems under a climate crisis in exacerbating conflicts in the Sahelian region and propose interventions beyond and complementary to the usual military and security solutions. We demonstrate for the Sahel that (i) climate hazards are frequent and exposure to climate variability is high, (ii) hotspots of high climate variability and conflict exist, and (iii) impact pathways by which climate exacerbates food systems that can lead to conflicts are documented in the literature. While these three findings suggest clear links between conflict and climate, we find that (iv) current peace indices do not include climate and food systems indicators and therefore provide an uncomplete picture, and (v) food systems programming for climate adaptation has so far not explicitly considered peace and security outcomes. Furthermore, we propose that food systems programming that truly tackles the climate crisis should take more explicit account of peace and security outcomes in conflict-affected areas.
We investigate the phased evolution and variation of the South Asian monsoon and resulting weathering intensity and physical erosion in the Himalaya–Karakoram Mountains since late Pliocene time (c. 3.4 Ma) using a comprehensive approach. Neodymium and strontium isotopic compositions and single-grain zircon U–Pb age spectra reveal the sources of the deposits in the east Arabian Sea, and show a combination of sources from the Himalaya and the Karakoram–Kohistan–Ladakh Mountains, with sediments from the Indian Peninsula such as the Deccan Traps or Craton. We interpret shifts in the sediment sources to have been forced by sea-level changes that correlate with South Asian monsoon rainfall variation since late Pliocene time. We collected 908 samples from the International Ocean Discovery Program Hole U1456A, which was drilled in the east Arabian Sea. Time series of hematite content and grain size of the sediments were examined downcore. We found South Asian monsoon precipitation and weathering intensity experienced three phases from late Pliocene time. Lower monsoon precipitation, with a lower variability and strong weathering intensity, occurred during 3.4–2.4 Ma; an increased and more variable South Asian monsoon rainfall, along with strengthened but fluctuating weathering intensity, occurred at 1.8–1.1 Ma; and a reduced rainfall with lower South Asian monsoon precipitation variability and moderate weathering intensity marked the period 1.1–0.1 Ma. Maximum entropy spectral analysis and wavelet transform show that there were orbital-dominated cycles of periods c. 100 and c. 41 ka in these proxy-based time series. We propose that the monsoon, sea level, global temperature and insolation together forced the weathering and erosion in SW Asia.
We describe an ultra-wide-bandwidth, low-frequency receiver recently installed on the Parkes radio telescope. The receiver system provides continuous frequency coverage from 704 to 4032 MHz. For much of the band (
${\sim}60\%$
), the system temperature is approximately 22 K and the receiver system remains in a linear regime even in the presence of strong mobile phone transmissions. We discuss the scientific and technical aspects of the new receiver, including its astronomical objectives, as well as the feed, receiver, digitiser, and signal processor design. We describe the pipeline routines that form the archive-ready data products and how those data files can be accessed from the archives. The system performance is quantified, including the system noise and linearity, beam shape, antenna efficiency, polarisation calibration, and timing stability.
The spatial pattern of accumulation rate can be inferred from internal layers in glaciers and ice sheets. Non-dimensional analysis determines where finite strain can be neglected (‘shallow-layer approximation’) or approximated with a local one-dimensional flow model (‘local-layer approximation’), and where gradients in strain rate along particle paths must be included (‘deep layers’). We develop a general geophysical inverse procedure to infer the spatial pattern of accumulation rate along a steady-state flowband, using measured topography of the ice-sheet surface, bed and a ‘deep layer’. A variety of thermomechanical ice-flow models can be used in the forward problem to calculate surface topography and ice velocity, which are used to calculate particle paths and internal-layer shapes. An objective tolerance criterion prevents over-fitting the data. After making site-specific simplifications in the thermomechanical flow algorithm, we find the accumulation rate along a flowband through Taylor Mouth, a flank site on Taylor Dome, Antarctica, using a layer at approximately 100 m depth, or 20% of the ice thickness. Accumulation rate correlates with ice-surface curvature. At this site, gradients along flow paths critically impact inference of both the accumulation pattern, and the depth-age relation in a 100 m core.
Deposition of snow from precipitation and wind events creates layering within seasonal snowpacks. The thickness and horizontal continuity of layers within seasonal snowpacks can be highly variable, due to snow blowing around topography and vegetation, and this has important implications for hydrology, remote sensing and avalanche forecasting. In this paper, we present practical field and post-processing protocols for recording lateral variations in snow stratigraphy using near-infrared (NIR) photography. A Fuji S9100 digital camera, modified to be sensitive to NIR wavelengths, was mounted on a rail system that allowed for rapid imaging of a 10 m long snow trench excavated on the north side of Toolik Lake, Alaska (68°38′ N, 149°36′ W). Post-processing of the images included removal of lens distortion and vignetting. A tape measure running along the base of the trench provided known locations (control points) that permitted scaling and georeferencing. Snow layer heights estimated from the NIR images compared well with manual stratigraphic measurements made at 0.2 m intervals along the trench (n = 357, R2 = 0.97). Considerably greater stratigraphic detail was captured by the NIR images than in the manually recorded profiles. NIR imaging of snow trenches using the described protocols is an efficient tool for quantifying continuous microscale variations in snow layers and associated properties.
There is a need for clinical tools to identify cultural issues in diagnostic assessment.
Aims
To assess the feasibility, acceptability and clinical utility of the DSM-5 Cultural Formulation Interview (CFI) in routine clinical practice.
Method
Mixed-methods evaluation of field trial data from six countries. The CFI was administered to diagnostically diverse psychiatric out-patients during a diagnostic interview. In post-evaluation sessions, patients and clinicians completed debriefing qualitative interviews and Likert-scale questionnaires. The duration of CFI administration and the full diagnostic session were monitored.
Results
Mixed-methods data from 318 patients and 75 clinicians found the CFI feasible, acceptable and useful. Clinician feasibility ratings were significantly lower than patient ratings and other clinician-assessed outcomes. After administering one CFI, however, clinician feasibility ratings improved significantly and subsequent interviews required less time.
Conclusions
The CFI was included in DSM-5 as a feasible, acceptable and useful cultural assessment tool.
Genome wide association studies (GWAS) have largely succeeded family-based linkage studies in livestock and human populations as the preferred method to map loci for complex or quantitative traits. However, the type of results produced by the two analyses contrast sharply due to differences in linkage disequilibrium (LD) imposed by the design of studies. In this paper, we demonstrate that association and linkage studies are in agreement provided that (i) the effects from both studies are estimated appropriately as random effects, (ii) all markers are fitted simultaneously and (iii) appropriate adjustments are made for the differences in LD between the study designs. We demonstrate with real data that linkage results can be predicted by the sum of association effects. Our association study captured most of the linkage information because we could predict the linkage results with moderate accuracy. We suggest that the ability of common single nucleotide polymorphism (SNP) to capture the genetic variance in a population will depend on the effective population size of the study organism. The results provide further evidence for many loci of small effect underlying complex traits. The analysis suggests a more informed method for GWAS is to fit statistical models where all SNPs are analysed simultaneously and as random effects.
Transnational non-governmental organizations (TNGOs) in general, and advocacy groups in particular, have gained considerable visibility and influence in global affairs. Since its creation in 1961, Amnesty International has become an authority on human rights issues around the world. Oxfam, Greenpeace, and Doctors Without Borders have gained a similar status on global issues related to development, the environment, and humanitarian relief, respectively. As these organizations have become significant players in global affairs, scholars across a variety of academic fields have begun to analyze the power of transnational advocacy organizations and their networks (Keck and Sikkink, 1998). The majority of early studies in the academic field of international relations viewed advocacy organizations as altruistic actors seeking to advance universally accepted principles. More recent scholarship responding to the principled advocacy literature has argued that TNGOs are better understood as interest-driven actors motivated primarily by the imperative of organizational survival in a competitive environment (Cooley and Ron, 2002; Bob, 2005; Ron, Ramos, and Rodgers, 2005).
In this chapter, we take a different approach to the study of advocacy organizations by inquiring into the nature of transnational advocacy itself as well as its organization as a collective endeavor at both the level of individual organizations and the level of networks. To answer questions about the role of advocacy in contemporary transnational activism, we rely on evidence collected in a large-scale study based on 152 interviews with leaders of transnational non-governmental organizations registered in the United States.