We generated a 5.5-yr snapshot of biweekly-to-monthly resolved time series of carbon and oxygen isotope composition (δ13C and δ18O) and Sr/Ca and Mg/Ca from annually banded aragonite skeleton of a ~ 197 ka pristine Porites coral collected at Niue Island (19°00′S, 169°50′W) in the southwestern subtropical Pacific Ocean. This report is the first of a high-resolution coral-based paleoclimate archive during the Marine Isotope Stage (MIS) 7 interglacial. Statistical results suggest that annual averages of sea-surface temperature (SST) and salinity (SSS) at ~ 197 ka were not significantly different from and ~ 1.2 higher than at present, respectively. Monthly mean variations showed increased SSS at ~ 197 ka that was higher (1.4–1.9 relative to today) in the austral summer than in the austral winter. Monthly SST and SSS anomalies at ~ 197 ka indicated smaller amplitudes by ~ 0.3°C (11%) and ~ 0.3 (24%) relative to the present, possibly suggesting less influence of interannual climate variability around Niue. Our results, taken together with other climate proxy records, imply seasonal and interannual modulation of thermal and hydrological conditions, different from today, in the southwestern subtropical Pacific Ocean associated with the Western Pacific Warm Pool and the South Pacific Convergence Zone variability during the MIS 7 interglacial.