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Follow-up blood cultures in Pseudomonas aeruginosa bacteremia: A potential target for diagnostic stewardship
- Alexis L. Green, Yuanyuan Liang, Lyndsay M. O’Hara, Lisa Pineles, Scott Sorongon, Anthony D. Harris, Jonathan D. Baghdadi
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- Journal:
- Antimicrobial Stewardship & Healthcare Epidemiology / Volume 1 / Issue 1 / 2021
- Published online by Cambridge University Press:
- 27 August 2021, e23
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Objectives:
Evidence supporting collection of follow-up blood cultures for Gram-negative bacteremia is mixed. We sought to understand why providers order follow-up blood cultures when managing P. aeruginosa bacteremia and whether follow-up blood cultures in this context are associated with short- and long-term survival.
Methods:We conducted a retrospective cohort study of adult inpatients with P. aeruginosa bacteremia at the University of Maryland Medical Center in 2015–2020. Kaplan-Meier survival curves and Cox regression with time-varying covariates were used to evaluate the association between follow-up blood cultures and time to mortality within 30 days of first positive blood culture. Provider justifications for follow-up blood cultures were identified through chart review.
Results:Of 159 eligible patients, 127 (80%) had follow-up blood cultures, including 9 (7%) that were positive for P. aeruginosa and 10 (8%) that were positive for other organisms. Follow-up blood cultures were typically collected “to ensure clearance” or “to guide antibiotic therapy.” Overall, 30-day mortality was 25.2%. After risk adjustment for patient characteristics, follow-up blood cultures were associated with a nonsignificant reduction in mortality risk (hazard ratio, 0.43; 95% confidence interval, 1.08; P = .071). In exploratory analyses, the potential mortality reduction from follow-up blood cultures was driven by their use in patients with Pitt bacteremia scores >0.
Conclusions:Follow-up blood cultures are commonly collected for P. aeruginosa bacteremia but infrequently identify persistent bacteremia. Targeted use of follow-up blood cultures based on severity of illness may reduce unnecessary culturing.
PION: Simulations of Wind-Blown Nebulae
- Jonathan Mackey, Samuel Green, Maria Moutzouri, Thomas J. Haworth, Robert D. Kavanagh, Maggie Celeste, Robert Brose, Davit Zargaryan, Ciarán O’Rourke
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- Journal:
- Proceedings of the International Astronomical Union / Volume 16 / Issue S362 / June 2020
- Published online by Cambridge University Press:
- 20 January 2023, pp. 262-267
- Print publication:
- June 2020
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We present an overview of PION, an open-source software project for solving radiation-magnetohydrodynamics equations on a nested grid, aimed at modelling asymmetric nebulae around massive stars. A new implementation of hybrid OpenMP/MPI parallel algorithms is briefly introduced, and improved scaling is demonstrated compared with the current release version. Three-dimensional simulations of an expanding nebula around a Wolf-Rayet star are then presented and analysed, similar to previous 2D simulations in the literature. The evolution of the emission measure of the gas and the X-ray surface brightness are calculated as a function of time, and some qualitative comparison with observations is made.
United States
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- By W Jonathan Cardi, Professor of Law, Wake Forest School of Law, United States, Michael D Green, Williams Professor of Law, Wake Forest School of Law, United States
- Edited by Miquel Martin-Casals
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- Book:
- The Borderlines of Tort Law
- Published by:
- Intersentia
- Published online:
- 15 November 2019
- Print publication:
- 29 August 2019, pp 617-668
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Summary
In the United States, both tort and contract law are generally matters of state rather than federal law. While there is a common core to both tort and contract doctrines in the US, one can find variation – sometimes narrow but sometimes broad – across the 51 independent state jurisdictions. In this United States country report, we attempt to provide a synthesis of state law while also trying to point out states whose laws deviate significantly from the synthesis.
QUESTIONS
TRACING THE BORDERLINES
The bases for liability in tort and contract are thought of as distinct in the US. The phrase ‘law of obligations’ is largely unknown in the United States. Contractual obligations are derived from the agreement of the parties to a contract that sets forth the bilateral obligations of the parties. By contrast, tort duties are imposed on parties by operation of law. This clean conceptual separation can break down in a number of contexts in which a tort occurs in a relationship where there is also a contract or potential contract between the parties, and where a contract is meant to benefit a third party. Medical and other professional malpractice, products liability, landlords’ obligations for defects in rented premises, implied warranties and other terms in contracts, and contractual waivers of tort liability are among the instances in which this occurs.
A court's characterization of an action as tort or contract matters for several reasons. Statutes of limitations typically limit tort actions to two years from the date of discovery of injury; contract actions typically are given four years from the date of material breach. Insurance contracts and principles of governmental immunity sometimes turn on the nature of the claim. The standard for liability is also quite different – to prevail in the typical tort case, a plaintiff must prove negligence; breach of contract requires no such proof, but merely that the defendant breached the agreed-upon terms. In addition, the applicable damages rules are different – rules regarding mitigation, scope of liability (proximate cause), non-pecuniary losses, and punitive damages are much more permissive in the tort context than in contract. Indeed, even some rules that tort and contract actions share – eg causation – are applied differently in sometimes outcome-determinative ways.
2,4-D deposition is reduced and more variable immediately adjacent to cereal rye cover crop rows
- Erin R. Haramoto, Austin D. Sherman, Jonathan D. Green
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- Journal:
- Weed Technology / Volume 34 / Issue 1 / February 2020
- Published online by Cambridge University Press:
- 23 August 2019, pp. 147-152
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Horseweed, also known as marestail, is a problematic weed for no-till soybean producers that can emerge from late summer through the following spring. Overwintering cover crops can reduce both the density and size of fall-emerged weeds such as horseweed and reduce further spring emergence, although typically cover crops do not provide complete control. Cover crops may be integrated with additional spring herbicide applications to control emerged horseweed, and selective herbicides such as 2,4-D may be used to target horseweed while maintaining small grain cover crop growth. However, cover crops may affect herbicide deposition, which could reduce their efficacy to control weeds. The objective of this study was to determine how the amount and variability of 2,4-D ester spray solution deposition, measured with water-sensitive paper, was affected by a cereal rye cover crop and fall-applied saflufenacil. We also examined deposition at the soil surface relative to the cereal rye row position. In a year with greater cereal rye biomass accumulation, there was 44% less coverage and average deposit size was 45% smaller immediately adjacent to cereal rye rows compared with between rows and areas without cereal rye. Greater variability in these measurements was also noted in this position. Percent spray solution coverage was also 22% greater in plots that received saflufenacil in the fall, and deposits were 28% larger. In a year with less cover crop and winter weed biomass, no differences in spray deposition were observed. This suggests that small horseweed plants and other weeds immediately adjacent to cereal rye cover crop rows may be more likely to survive early spring herbicide applications, though the suppressive effects of cover crops may mitigate this concern.
Coevolution of resistance to PPO inhibitors in waterhemp (Amaranthus tuberculatus) and Palmer amaranth (Amaranthus palmeri)
- Kathryn J. Lillie, Darci A. Giacomini, Jonathan D. Green, Patrick J. Tranel
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- Journal:
- Weed Science / Volume 67 / Issue 5 / September 2019
- Published online by Cambridge University Press:
- 14 August 2019, pp. 521-526
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The first case of evolved protoporphyrinogen oxidase (PPO)-inhibitor resistance was observed in 2001 in common waterhemp [Amaranthus tuberculatus (Moq.) Sauer var. rudis (Sauer) Costea and Tardif]. This resistance in A. tuberculatus is most commonly conferred by deletion of the amino acid glycine at the 210th position (ΔGly-210) of the PPO enzyme (PPO2) encoded by PPX2. In a field in Kentucky in 2015, inadequate control of Amaranthus plants was observed following application of a PPO inhibitor. Morphological observations indicated that survivors included both A. tuberculatus and Palmer amaranth (Amaranthus palmeri S. Watson). Research was conducted to confirm species identities and resistance and then to determine whether resistance evolved independently in the two species or via hybridization. Results from a quantitative PCR assay based on the ribosomal internal transcribed spacer confirmed that both A. tuberculatus and A. palmeri coexisted in the field. The mutation conferring ΔGly-210 in PPO2 was identified in both species; phylogenetic analysis of a region of PPX2, however, indicated that the mutation evolved independently in the two species. Genotyping of greenhouse-grown plants that survived lactofen indicated that all A. tuberculatus survivors, but only a third of A. palmeri survivors, contained the ΔGly-210 mutation. Consequently, A. palmeri plants were evaluated for the presence of an arginine to glycine or methionine substitution at position 128 of PPO2 (Arg-128-Gly and Arg-128-Met). The Arg-128-Gly substitution was found to account for resistance that was not accounted for by the ΔGly-210 mutation in plants from the A. palmeri population. Results from this study provide a modern-day example of both parallel and convergent evolution occurring within a single field.
Tall Ironweed (Vernonia altissima Nutt.) Control in Pastures with Fall-Applied Herbicides
- Michael W. Marshall, Jonathan D. Green, David C. Ditsch, J. Wade Turner
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- Journal:
- Weed Technology / Volume 20 / Issue 1 / March 2006
- Published online by Cambridge University Press:
- 20 January 2017, pp. 52-57
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Tall ironweed is a troublesome perennial weed that infests cool-season grass pastures in Kentucky. Field experiments were conducted in 2000 through 2003 to evaluate the efficacy of fall-applied herbicides on established tall ironweed following a midsummer mowing. Triclopyr-containing treatments showed the greatest suppression of tall ironweed 12 mo after treatment (MAT), across all years. With triclopyr at 0.56 and 0.63 kg/ha, tall ironweed control was 80% or greater in 2 of the 3 yr. Dicamba initially provided 87% control 8 MAT in 2 of 3 yr and declined to less than 60% 12 MAT. Tall ironweed shoot density was also reduced 66% or more 12 MAT with fall-applied triclopyr-containing treatments. In contrast, tall ironweed density increased approximately twofold in dicamba-treated plots between 8 to 12 MAT in all 3 yr. The impact of herbicide treatment on dry matter (DM) yield of spring-seeded red clover (Trifolium pratense L.), tall ironweed, and forage grasses was also evaluated. Red clover DM yield in the herbicide-treated plots in 2002 showed no significant differences from the untreated control. However, red clover DM yield in 2003 was lowest for the two triclopyr + clopyralid treatments, indicating a decrease in DM production compared with that of the nontreated control. Results indicated that fall-applied triclopyr-containing herbicides following a midsummer mowing is an effective program for removing tall ironweed from grass pastures, but further research is needed to evaluate the establishment of red clover following herbicide treatment.
Utility of Aminocyclopyrachlor for Control of Horsenettle (Solanum carolinense) and Tall Ironweed (Vernonia gigantea) in Cool-Season Grass Pastures
- William P. Phillips, Trevor D. Israel, Thomas C. Mueller, Gregory R. Armel, Dennis R. West, Jonathan D. Green, G. Neil Rhodes, Jr.
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- Journal:
- Weed Technology / Volume 30 / Issue 2 / June 2016
- Published online by Cambridge University Press:
- 20 January 2017, pp. 472-477
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Because horsenettle and tall ironweed are difficult to control in cool-season grass pastures, research was conducted in Tennessee and Kentucky in 2010 and 2011 to examine the efficacy of aminocyclopyrachlor on these weeds. Aminocyclopyrachlor was evaluated at 49 and 98 g ai ha−1 alone and in mixtures with 2,4-D amine at 371 and 742 g ae ha−1. Aminopyralid was also included as a comparison treatment at 88 g ai ha−1. Treatments were applied at three POST timings to horsenettle and two POST timings to tall ironweed. By 1 yr after treatment (YAT) horsenettle was controlled 74% with aminocyclopyrachlor plus 2,4-D applied late POST (LPOST) at 98 + 742 g ha−1. By 1 YAT, tall ironweed was controlled ≥ 93% by aminocyclopyrachlor applied early POST (EPOST) or LPOST, at rates as low as 49 g ha−1. Similar control was achieved with aminopyralid applied LPOST. Both aminocyclopyrachlor and aminopyralid were found to reduce horsenettle and tall ironweed biomass the following year. Moreover, all LPOST applications of aminocyclopyrachlor alone or in mixtures with 2,4-D prevented regrowth of tall ironweed at 1 YAT. Based on these studies, a LPOST herbicide application in August or September when soil moisture is adequate is recommended for control of horsenettle and tall ironweed in cool-season grass pastures.
The United States
- from PART I - PUBLIC AUTHORITY LIABILITY OUTLINED
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- By Michael D Green, Williams Professor of Law, Wake Forest University School of Law, United States, Jonathan Cardi, Professor of Law, Wake Forest School of Law, United States
- Ken Oliphant
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- Book:
- The Liability of Public Authorities in Comparative Perspective
- Published by:
- Intersentia
- Published online:
- 27 November 2017
- Print publication:
- 26 October 2016, pp 537-558
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Summary
INTRODUCTION
OVERVIEW
An initial word about terminology. ‘Public authority liability’ is not the term that would be used in the United States to describe the rules governing liability of public entities. Instead, the almost universal terminology is ‘governmental liability’ or ‘governmental immunity’. One popular treatise does employ the term ‘public entities officers and employees’ liability, although it also uses ‘governmental entities’ liability when focused on the liability of those entities apart from their employees and officials.
Public authority liability in the United States, because of its federal system, is divided between states, which are co-equal sovereigns, and the United States. Federal law addresses the liability of the federal government and its employees, while state law governs the liability of individual states and their employees. One qualification to the above statement of source of law is that federal constitutional provisions can be the basis for liability of state employees and in some instances the basis for injunctive relief as well.
Although the traditional blanket immunity for sovereign entities has long since been abrogated, governmental entities and officials retain a large amount of freedom from tort liability, particularly with regard to ‘discretionary’ decisions made in the course of governing. This area of the law is dominated by statutes – with the Federal Tort Claims Act (FTCA) governing federal liability and virtually every state having its own counterpart. Public authority liability thus involves adoption of universal principles of private tort law, along with modifications – oft en in the form of limitations on the liability of public authorities – contained in the FTCA.
Pursuant to the FTCA, the federal government may be liable for actions in its sphere, including regulatory efforts. Similarly, state governments (and substate governmental units) may be liable for actions in their sphere, including regulatory actions.
With 51 independent state jurisdictions, there is considerable variation that exists in the law governing liability of public entities and public employees.
United States of America
- from Part II
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- By Michael D Green, Williams Professor of Law, Wake Forest University School of Law, United States, Jonathan Cardi, Professor of Law and Associate Dean for Research and Development, Wake Forest School of Law, United States
- Edited by Piotr Machnikowski
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- Book:
- European Product Liability
- Published by:
- Intersentia
- Published online:
- 15 December 2017
- Print publication:
- 02 August 2016, pp 575-616
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Summary
INTRODUCTION
In the US, the substantive rules of product liability are primarily determined by state courts and legislatures. Because the US has a common law system, state courts have played an especially important role in the area of product liability and tort more generally. While strict product liability was developed exclusively by state courts, once it became established, some state legislatures enacted statutes to govern product liability cases. The more comprehensive ones tended to adopt the law that had developed through the common law and place it into statutory form. In some cases, those statutes modified one or more aspects of product liability law that the courts had developed. In addition, the US has had several rounds of ‘tort reform’, in which state legislatures have restricted tort law, and some of those reforms were targeted specifically at product liability claims or, because of their breadth, encompassed product claims as well as other tort claims.
It is true that federal law sets some important limits on state product liability law in certain areas subject to federal regulation. For example, because, under the US Constitution, federal law pre-empts conflicting state law, manufacturers of generic drugs, medical devices, and automobiles who have satisfied federal-law regulations with respect to safe product design, or warnings of product risks, are sometimes immune from liability under state tort law. In addition, the US Supreme Court has identified federal constitutional limits on when, how, and in what amounts punitive damages may be awarded. Still, state law is the primary source of law governing liability for product-related injuries.
It would be a significant overstatement to say that, in substance, the US has 51 different versions of product liability law: there is a good deal of uniformity across the product liability law of each state and the District of Columbia. But there are also important differences, and thus it is oft en inaccurate to speak and write as if there were a single US product liability law. In what follows, we will aim to address the product liability issues confronted in this volume by reference to legal rules that have gained broad acceptance across the different US jurisdictions, and we will also try to note areas in which the law varies significantly among jurisdictions.
An Environmental Scan of Academic Emergency Medicine at the 17 Canadian Medical Schools: Why Does this Matter to Emergency Physicians?
- Ian G. Stiell, Jennifer D. Artz, Eddy S. Lang, Jonathan Sherbino, Laurie J. Morrison, James Christenson, Jeffrey J. Perry, Claude Topping, Robert Woods, Robert S. Green, Rodrick Lim, Kirk Magee, John Foote, Garth Meckler, Mark Mensour, Simon Field, Brian Chung, Martin Kuuskne, James Ducharme, Vera Klein, Jill McEwen
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- Journal:
- Canadian Journal of Emergency Medicine / Volume 19 / Issue 1 / January 2017
- Published online by Cambridge University Press:
- 21 July 2016, pp. 39-46
- Print publication:
- January 2017
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Objective
We sought to conduct a major objective of the CAEP Academic Section, an environmental scan of the academic emergency medicine programs across the 17 Canadian medical schools.
MethodsWe developed an 84-question questionnaire, which was distributed to academic heads. The responses were validated by phone by the lead author to ensure that the questions were answered completely and consistently. Details of pediatric emergency medicine units were excluded from the scan.
ResultsAt eight of 17 universities, emergency medicine has full departmental status and at two it has no official academic status. Canadian academic emergency medicine is practiced at 46 major teaching hospitals and 13 specialized pediatric hospitals. Another 69 Canadian hospital EDs regularly take clinical clerks and emergency medicine residents. There are 31 full professors of emergency medicine in Canada. Teaching programs are strong with clerkships offered at 16/17 universities, CCFP(EM) programs at 17/17, and RCPSC residency programs at 14/17. Fourteen sites have at least one physician with a Master’s degree in education. There are 55 clinical researchers with salary support at 13 universities. Sixteen sites have published peer-reviewed papers in the past five years, ranging from four to 235 per site. Annual budgets range from $200,000 to $5,900,000.
ConclusionThis comprehensive review of academic activities in emergency medicine across Canada identifies areas of strengths as well as opportunities for improvement. CAEP and the Academic Section hope we can ultimately improve ED patient care by sharing best academic practices and becoming better teachers, educators, and researchers.
Contributors
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- By Rony A. Adam, Gloria Bachmann, Nichole M. Barker, Randall B. Barnes, John Bennett, Inbar Ben-Shachar, Jonathan S. Berek, Sarah L. Berga, Monica W. Best, Eric J. Bieber, Frank M. Biro, Shan Biscette, Anita K. Blanchard, Candace Brown, Ronald T. Burkman, Joseph Buscema, John E. Buster, Michael Byas-Smith, Sandra Ann Carson, Judy C. Chang, Annie N. Y. Cheung, Mindy S. Christianson, Karishma Circelli, Daniel L. Clarke-Pearson, Larry J. Copeland, Bryan D. Cowan, Navneet Dhillon, Michael P. Diamond, Conception Diaz-Arrastia, Nicole M. Donnellan, Michael L. Eisenberg, Eric Eisenhauer, Sebastian Faro, J. Stuart Ferriss, Lisa C. Flowers, Susan J. Freeman, Leda Gattoc, Claudine Marie Gayle, Timothy M. Geiger, Jennifer S. Gell, Alan N. Gordon, Victoria L. Green, Jon K. Hathaway, Enrique Hernandez, S. Paige Hertweck, Randall S. Hines, Ira R. Horowitz, Fred M. Howard, William W. Hurd, Fidan Israfilbayli, Denise J. Jamieson, Carolyn R. Jaslow, Erika B. Johnston-MacAnanny, Rohna M. Kearney, Namita Khanna, Caroline C. King, Jeremy A. King, Ira J. Kodner, Tamara Kolev, Athena P. Kourtis, S. Robert Kovac, Ertug Kovanci, William H. Kutteh, Eduardo Lara-Torre, Pallavi Latthe, Herschel W. Lawson, Ronald L. Levine, Frank W. Ling, Larry I. Lipshultz, Steven D. McCarus, Robert McLellan, Shruti Malik, Suketu M. Mansuria, Mohamed K. Mehasseb, Pamela J. Murray, Saloney Nazeer, Farr R. Nezhat, Hextan Y. S. Ngan, Gina M. Northington, Peggy A. Norton, Ruth M. O'Regan, Kristiina Parviainen, Resad P. Pasic, Tanja Pejovic, K. Ulrich Petry, Nancy A. Phillips, Ashish Pradhan, Elizabeth E. Puscheck, Suneetha Rachaneni, Devon M. Ramaeker, David B. Redwine, Robert L. Reid, Carla P. Roberts, Walter Romano, Peter G. Rose, Robert L. Rosenfield, Shon P. Rowan, Mack T. Ruffin, Janice M. Rymer, Evis Sala, Ritu Salani, Joseph S. Sanfilippo, Mahmood I. Shafi, Roger P. Smith, Meredith L. Snook, Thomas E. Snyder, Mary D. Stephenson, Thomas G. Stovall, Richard L. Sweet, Philip M. Toozs-Hobson, Togas Tulandi, Elizabeth R. Unger, Denise S. Uyar, Marion S. Verp, Rahi Victory, Tamara J. Vokes, Michelle J. Washington, Katharine O'Connell White, Paul E. Wise, Frank M. Wittmaack, Miya P. Yamamoto, Christine Yu, Howard A. Zacur
- Edited by Eric J. Bieber, Joseph S. Sanfilippo, University of Pittsburgh, Ira R. Horowitz, Emory University, Atlanta, Mahmood I. Shafi
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- Book:
- Clinical Gynecology
- Published online:
- 05 April 2015
- Print publication:
- 23 April 2015, pp viii-xiv
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Authors' reply
- Jonathan Green, N. Biehal, C. Roberts, J. Dixon, C. Kay, E. Parry, J. Rothwell, A. Roby, D. Kapadia, S. Scott, I. Sinclair
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- Journal:
- The British Journal of Psychiatry / Volume 205 / Issue 6 / December 2014
- Published online by Cambridge University Press:
- 02 January 2018, pp. 498-499
- Print publication:
- December 2014
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- By André Aleman, Narmeen Ammari, Alan Anticevic, Deanna M. Barch, Christopher R. Bowie, Katherine E. Burdick, Sara J. Czaja, Anthony S. David, Colin A. Depp, Dwight Dickinson, Gary Donohoe, Melissa Fisher, Benjamin Glicksberg, Michael F. Green, Maya Gupta, Philip D. Harvey, R. Walter Heinrichs, Katherine Holshausen, William P. Horan, Daniel C. Javitt, Richard Keefe, John H. Krystal, David Loewenstein, Susan R. McGurk, Kristopher I. Mathis, Brent Mausbach, Ashley A. Miles, Kim T. Mueser, Eva Muharib, Robin Murray, Akshay Nair, Rogerio Panizzutti, Thomas Patterson, Amy E. Pinkham, Abraham Reichenberg, Manuela Russo, Jonathan Schaefer, Karuna Subramaniam, Laura Vergel de Dios, Sophia Vinogradov, Daniel R. Weinberger, Jonathan K. Wynn
- Edited by Philip D. Harvey, University of Miami
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- Book:
- Cognitive Impairment in Schizophrenia
- Published online:
- 05 February 2013
- Print publication:
- 24 January 2013, pp vii-x
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Linking agriculture and health in low- and middle-income countries: an interdisciplinary research agenda
- Alan D. Dangour, Rosemary Green, Barbara Häsler, Jonathan Rushton, Bhavani Shankar, Jeff Waage
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- Journal:
- Proceedings of the Nutrition Society / Volume 71 / Issue 2 / May 2012
- Published online by Cambridge University Press:
- 16 March 2012, pp. 222-228
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Recent global fluctuations in food prices and continuing environmental degradation highlight the future challenge of feeding a growing world population. However, current dialogues rarely address the relationship between agricultural changes and health. This relationship is traditionally associated with the role of food in nutrition and with food safety, and while these are key interactions, we show in this paper that the relationship is far more complex and interesting. Besides the direct effects of agriculture on population nutrition, agriculture also influences health through its impact on household incomes, economies and the environment. These effects are felt particularly in low- and middle-income countries, where dramatic changes are affecting the agriculture–health relationship, in particular the growth of nutrition-related chronic disease and the associated double burden of under- and over-nutrition. Greater understanding of the negative effects of agriculture on health is also needed. While lengthening food value chains make the chain of influence between agricultural policy, food consumption, nutrition and health more complex, there remain opportunities to improve health by changing agricultural systems. The first challenge in doing this, we suggest, is to improve our capacity to measure the impact of agricultural interventions on health outcomes, and vice versa.
Contributors
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- By Rose Teteki Abbey, K. C. Abraham, David Tuesday Adamo, LeRoy H. Aden, Efrain Agosto, Victor Aguilan, Gillian T. W. Ahlgren, Charanjit Kaur AjitSingh, Dorothy B E A Akoto, Giuseppe Alberigo, Daniel E. Albrecht, Ruth Albrecht, Daniel O. Aleshire, Urs Altermatt, Anand Amaladass, Michael Amaladoss, James N. Amanze, Lesley G. Anderson, Thomas C. Anderson, Victor Anderson, Hope S. Antone, María Pilar Aquino, Paula Arai, Victorio Araya Guillén, S. Wesley Ariarajah, Ellen T. Armour, Brett Gregory Armstrong, Atsuhiro Asano, Naim Stifan Ateek, Mahmoud Ayoub, John Alembillah Azumah, Mercedes L. García Bachmann, Irena Backus, J. Wayne Baker, Mieke Bal, Lewis V. Baldwin, William Barbieri, António Barbosa da Silva, David Basinger, Bolaji Olukemi Bateye, Oswald Bayer, Daniel H. Bays, Rosalie Beck, Nancy Elizabeth Bedford, Guy-Thomas Bedouelle, Chorbishop Seely Beggiani, Wolfgang Behringer, Christopher M. Bellitto, Byard Bennett, Harold V. Bennett, Teresa Berger, Miguel A. Bernad, Henley Bernard, Alan E. Bernstein, Jon L. Berquist, Johannes Beutler, Ana María Bidegain, Matthew P. Binkewicz, Jennifer Bird, Joseph Blenkinsopp, Dmytro Bondarenko, Paulo Bonfatti, Riet en Pim Bons-Storm, Jessica A. Boon, Marcus J. Borg, Mark Bosco, Peter C. Bouteneff, François Bovon, William D. Bowman, Paul S. Boyer, David Brakke, Richard E. Brantley, Marcus Braybrooke, Ian Breward, Ênio José da Costa Brito, Jewel Spears Brooker, Johannes Brosseder, Nicholas Canfield Read Brown, Robert F. Brown, Pamela K. Brubaker, Walter Brueggemann, Bishop Colin O. Buchanan, Stanley M. Burgess, Amy Nelson Burnett, J. Patout Burns, David B. Burrell, David Buttrick, James P. Byrd, Lavinia Byrne, Gerado Caetano, Marcos Caldas, Alkiviadis Calivas, William J. Callahan, Salvatore Calomino, Euan K. Cameron, William S. Campbell, Marcelo Ayres Camurça, Daniel F. Caner, Paul E. Capetz, Carlos F. Cardoza-Orlandi, Patrick W. Carey, Barbara Carvill, Hal Cauthron, Subhadra Mitra Channa, Mark D. Chapman, James H. Charlesworth, Kenneth R. Chase, Chen Zemin, Luciano Chianeque, Philip Chia Phin Yin, Francisca H. Chimhanda, Daniel Chiquete, John T. Chirban, Soobin Choi, Robert Choquette, Mita Choudhury, Gerald Christianson, John Chryssavgis, Sejong Chun, Esther Chung-Kim, Charles M. A. Clark, Elizabeth A. Clark, Sathianathan Clarke, Fred Cloud, John B. Cobb, W. Owen Cole, John A Coleman, John J. Collins, Sylvia Collins-Mayo, Paul K. Conkin, Beth A. Conklin, Sean Connolly, Demetrios J. Constantelos, Michael A. Conway, Paula M. Cooey, Austin Cooper, Michael L. Cooper-White, Pamela Cooper-White, L. William Countryman, Sérgio Coutinho, Pamela Couture, Shannon Craigo-Snell, James L. Crenshaw, David Crowner, Humberto Horacio Cucchetti, Lawrence S. Cunningham, Elizabeth Mason Currier, Emmanuel Cutrone, Mary L. Daniel, David D. Daniels, Robert Darden, Rolf Darge, Isaiah Dau, Jeffry C. Davis, Jane Dawson, Valentin Dedji, John W. de Gruchy, Paul DeHart, Wendy J. Deichmann Edwards, Miguel A. De La Torre, George E. Demacopoulos, Thomas de Mayo, Leah DeVun, Beatriz de Vasconcellos Dias, Dennis C. Dickerson, John M. Dillon, Luis Miguel Donatello, Igor Dorfmann-Lazarev, Susanna Drake, Jonathan A. Draper, N. Dreher Martin, Otto Dreydoppel, Angelyn Dries, A. J. Droge, Francis X. D'Sa, Marilyn Dunn, Nicole Wilkinson Duran, Rifaat Ebied, Mark J. Edwards, William H. Edwards, Leonard H. Ehrlich, Nancy L. Eiesland, Martin Elbel, J. Harold Ellens, Stephen Ellingson, Marvin M. Ellison, Robert Ellsberg, Jean Bethke Elshtain, Eldon Jay Epp, Peter C. Erb, Tassilo Erhardt, Maria Erling, Noel Leo Erskine, Gillian R. Evans, Virginia Fabella, Michael A. Fahey, Edward Farley, Margaret A. Farley, Wendy Farley, Robert Fastiggi, Seena Fazel, Duncan S. Ferguson, Helwar Figueroa, Paul Corby Finney, Kyriaki Karidoyanes FitzGerald, Thomas E. FitzGerald, John R. Fitzmier, Marie Therese Flanagan, Sabina Flanagan, Claude Flipo, Ronald B. 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Yee, Viktor Yelensky, Yeo Khiok-Khng, Gustav K. K. Yeung, Angela Yiu, Amos Yong, Yong Ting Jin, You Bin, Youhanna Nessim Youssef, Eliana Yunes, Robert Michael Zaller, Valarie H. Ziegler, Barbara Brown Zikmund, Joyce Ann Zimmerman, Aurora Zlotnik, Zhuo Xinping
- Edited by Daniel Patte, Vanderbilt University, Tennessee
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- The Cambridge Dictionary of Christianity
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- 05 August 2012
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- 20 September 2010, pp xi-xliv
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Looking Backward, Looking Forward: MLA Members Speak
- April Alliston, Elizabeth Ammons, Jean Arnold, Nina Baym, Sandra L. Beckett, Peter G. Beidler, Roger A. Berger, Sandra Bermann, J.J. Wilson, Troy Boone, Alison Booth, Wayne C. Booth, James Phelan, Marie Borroff, Ihab Hassan, Ulrich Weisstein, Zack Bowen, Jill Campbell, Dan Campion, Jay Caplan, Maurice Charney, Beverly Lyon Clark, Robert A. Colby, Thomas C. Coleman III, Nicole Cooley, Richard Dellamora, Morris Dickstein, Terrell Dixon, Emory Elliott, Caryl Emerson, Ann W. Engar, Lars Engle, Kai Hammermeister, N. N. Feltes, Mary Anne Ferguson, Annie Finch, Shelley Fisher Fishkin, Jerry Aline Flieger, Norman Friedman, Rosemarie Garland-Thomson, Sandra M. Gilbert, Laurie Grobman, George Guida, Liselotte Gumpel, R. K. Gupta, Florence Howe, Cathy L. Jrade, Richard A. Kaye, Calhoun Winton, Murray Krieger, Robert Langbaum, Richard A. Lanham, Marilee Lindemann, Paul Michael Lützeler, Thomas J. Lynn, Juliet Flower MacCannell, Michelle A. Massé, Irving Massey, Georges May, Christian W. Hallstein, Gita May, Lucy McDiarmid, Ellen Messer-Davidow, Koritha Mitchell, Robin Smiles, Kenyatta Albeny, George Monteiro, Joel Myerson, Alan Nadel, Ashton Nichols, Jeffrey Nishimura, Neal Oxenhandler, David Palumbo-Liu, Vincent P. Pecora, David Porter, Nancy Potter, Ronald C. Rosbottom, Elias L. Rivers, Gerhard F. Strasser, J. L. Styan, Marianna De Marco Torgovnick, Gary Totten, David van Leer, Asha Varadharajan, Orrin N. C. Wang, Sharon Willis, Louise E. Wright, Donald A. Yates, Takayuki Yokota-Murakami, Richard E. Zeikowitz, Angelika Bammer, Dale Bauer, Karl Beckson, Betsy A. Bowen, Stacey Donohue, Sheila Emerson, Gwendolyn Audrey Foster, Jay L. Halio, Karl Kroeber, Terence Hawkes, William B. Hunter, Mary Jambus, Willard F. King, Nancy K. Miller, Jody Norton, Ann Pellegrini, S. P. Rosenbaum, Lorie Roth, Robert Scholes, Joanne Shattock, Rosemary T. VanArsdel, Alfred Bendixen, Alarma Kathleen Brown, Michael J. Kiskis, Debra A. Castillo, Rey Chow, John F. Crossen, Robert F. Fleissner, Regenia Gagnier, Nicholas Howe, M. Thomas Inge, Frank Mehring, Hyungji Park, Jahan Ramazani, Kenneth M. Roemer, Deborah D. Rogers, A. LaVonne Brown Ruoff, Regina M. Schwartz, John T. Shawcross, Brenda R. Silver, Andrew von Hendy, Virginia Wright Wexman, Britta Zangen, A. Owen Aldridge, Paula R. Backscheider, Roland Bartel, E. M. Forster, Milton Birnbaum, Jonathan Bishop, Crystal Downing, Frank H. Ellis, Roberto Forns-Broggi, James R. Giles, Mary E. Giles, Susan Blair Green, Madelyn Gutwirth, Constance B. Hieatt, Titi Adepitan, Edgar C. Knowlton, Jr., Emanuel Mussman, Sally Todd Nelson, Robert O. Preyer, David Diego Rodriguez, Guy Stern, James Thorpe, Robert J. Wilson, Rebecca S. Beal, Joyce Simutis, Betsy Bowden, Sara Cooper, Wheeler Winston Dixon, Tarek el Ariss, Richard Jewell, John W. Kronik, Wendy Martin, Stuart Y. McDougal, Hugo Méndez-Ramírez, Ivy Schweitzer, Armand E. Singer, G. Thomas Tanselle, Tom Bishop, Mary Ann Caws, Marcel Gutwirth, Christophe Ippolito, Lawrence D. Kritzman, James Longenbach, Tim McCracken, Wolfe S. Molitor, Diane Quantic, Gregory Rabassa, Ellen M. Tsagaris, Anthony C. Yu, Betty Jean Craige, Wendell V. Harris, J. Hillis Miller, Jesse G. Swan, Helene Zimmer-Loew, Peter Berek, James Chandler, Hanna K. Charney, Philip Cohen, Judith Fetterley, Herbert Lindenberger, Julia Reinhard Lupton, Maximillian E. Novak, Richard Ohmann, Marjorie Perloff, Mark Reynolds, James Sledd, Harriet Turner, Marie Umeh, Flavia Aloya, Regina Barreca, Konrad Bieber, Ellis Hanson, William J. Hyde, Holly A. Laird, David Leverenz, Allen Michie, J. Wesley Miller, Marvin Rosenberg, Daniel R. Schwarz, Elizabeth Welt Trahan, Jean Fagan Yellin
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- PMLA / Publications of the Modern Language Association of America / Volume 115 / Issue 7 / December 2000
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- 23 October 2020, pp. 1986-2078
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A NEW PROTOCOL FOR THE MEASUREMENT OF PICOMOLE QUANTITIES OF MAGNESIUM IN RAT RENAL TUBULAR FLUID
- JONATHAN D. KIBBLE, NEIL AUDSLEY, J. PHILIP DAY, ROGER GREEN
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- Experimental Physiology / Volume 83 / Issue 1 / January 1998
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- 03 January 2001, pp. 11-22
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- January 1998
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The analysis of picomolar quantities of magnesium by electrothermal atomic absorption spectrophotometry (EAAS) was studied using a Perkin-Elmer-Zeeman 3030 spectrophotometer. The absorbance signal was not heavily dependent on the atomization temperature, but was greatly reduced when ashing temperatures in excess of 1200¡C were applied. The magnesium signal was significantly depressed in the presence of excess chloride in the sample matrix. However, use of NH4NO3 as a matrix modifier was sufficient to overcome this artefact. The analytical sensitivity was 0·15 absorbance units pmol-1 and the detection limit was 0·04 pmol. Using nanolitre constriction pipettes to dispense standards, the mean coefficient of variation was 5 %. Measurement of magnesium handling in the rat proximal convoluted tubule revealed a significant correlation between the tubular fluid-to-plasma ultrafiltrate (TF/UF) concentration ratio for magnesium and the tubular fluid-to-plasma (TF/P) concentration ratio for [3H]inulin (r2 = 0·56, n = 17). This indicated that magnesium is concentrated during its passage along the proximal tubule. In contrast, this was not the case for sodium (r2 = 0·11, n = 16). Mean (TF/UF)Mg (1·16 ± 0·07, n = 17) for random punctures was significantly greater than that for sodium ((TF/UF)Na = 1·02 ± 0·02, n = 16). Despite concentration of magnesium in the lumen, significant net reabsorption of magnesium was observed along the length of the tubule (fractional reabsorption, FRMg = 19·4 ± 3·0 %, n = 17). In conclusion, EAAS provides a highly sensitive, reproducible and technically simple method for measuring picomolar quantities of magnesium in renal tubular fluid.