44 results
N-terminal pro-brain natriuretic peptide serum levels reflect attrition of the Fontan circulation
- Djoeke Wolff, Joost P. van Melle, Tineke P. Willems, Beatrijs Bartelds, Mark-Jan Ploegstra, Hans Hillege, Tjark Ebels, Rolf M. F. Berger
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- Journal:
- Cardiology in the Young / Volume 30 / Issue 6 / June 2020
- Published online by Cambridge University Press:
- 09 June 2020, pp. 753-760
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Objective:
N-terminal pro-brain natriuretic peptide has an established role in the diagnosis and prognosis of heart failure. In Fontan patients, this peptide is often increased, but its diagnostic value in this particular non-physiologic, univentricular circulation is unclear. We investigated whether N-terminal pro-brain natriuretic peptide represents ventricular function or other key variables in Fontan patients.
Methods and results:Ninety-five consecutive Fontan patients ≥10 years old who attended the outpatient clinic of the Center for Congenital Heart Diseases in 2012–2013 were included. Time since Fontan completion was 16 ± 9 years. Median N-terminal pro-brain natriuretic peptide was 114 (61–264) ng/l and was higher than gender-and age-dependent normal values in 54% of the patients. Peptide Z-scores were higher in patients in NYHA class III/IV compared to those in class I/II, but did not correlate with ventricular function assessed by MRI and echocardiography, nor with peak exercise capacity. Instead, peptide Z-scores significantly correlated with follow-up duration after Fontan completion (p < 0.001), right ventricular morphology (p = 0.004), indexed ventricular mass (p = 0.001), and inferior caval vein diameter (p < 0.001) (adjusted R2 = 0.615).
Conclusions:N-terminal pro-brain natriuretic peptide levels in Fontan patients correlate with functional class, but do not necessarily indicate ventricular dysfunction. Increased peptide levels were associated with a longer existence of the Fontan circulation, morphologic ventricular characteristics, and signs of increased systemic venous congestion. Since the latter are known to be key determinants of the performance of the Fontan circulation, these findings suggest increase in N-terminal pro-brain natriuretic peptide levels to indicate attrition of the Fontan circulation, independent of ventricular function.
The validity of self-rated psychotic symptoms in depressed inpatients
- F. Seemüller, M. Riedel, M. Obermeier, R. Schennach-Wolff, I. Spellmann, S. Meyer, M. Bauer, M. Adli, K. Kronmüller, M. Ising, P. Brieger, G. Laux, W. Bender, I. Heuser, J. Zeiler, W. Gaebel, H.-J. Möller
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- Journal:
- European Psychiatry / Volume 27 / Issue 7 / October 2012
- Published online by Cambridge University Press:
- 15 April 2020, pp. 547-552
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Background
Self-ratings of psychotic experiences might be biased by depressive symptoms.
MethodData from a large naturalistic multicentre trial on depressed inpatients (n = 488) who were assessed on a biweekly basis until discharge were analyzed. Self-rated psychotic symptoms as assessed with the 90-Item Symptom Checklist (SCL-90) were correlated with the SCL-90 total score, the SCL-90 depression score, the Beck Depression Inventory (BDI), the Hamilton Depression Rating Scale 21 item (HAMD-21) total score, the Montgomery Åsberg Depression Rating Scale (MADRS) total score and the clinician-rated paranoid-hallucinatory score of the Association for Methodology and Documentation in Psychiatry (AMDP) scale.
ResultsAt discharge the SCL-90 psychosis score correlated highest with the SCL-90 depression score (0.78, P<0.001) and with the BDI total score (0.64, P<0.001). Moderate correlations were found for the MADRS (0.34, P<0.001), HAMD (0.37, P<0.001) and AMDP depression score (0.33, P<0.001). Only a weak correlation was found between the SCL-90 psychosis score and the AMDP paranoid-hallucinatory syndrome score (0.15, P<0.001). Linear regression showed that change in self-rated psychotic symptoms over the treatment course was best explained by a change in the SCL-90 depression score (P<0.001). The change in clinician-rated AMDP paranoid-hallucinatory score had lesser influence (P = 0.02).
ConclusionsIn depressed patients self-rated psychotic symptoms correlate poorly with clinician-rated psychotic symptoms. Caution is warranted when interpreting results from epidemiological surveys using self-rated psychotic symptom questionnaires as indicators of psychotic symptoms. Depressive symptoms which are highly prevalent in the general population might influence such self-ratings.
Comparison of analytical methods used for measuring major ions in the EPICA Dome C (Antarctica) ice core
- Geneviève C. Littot, Robert Mulvaney, Regine Röthlisberger, Roberto Udisti, Eric W. Wolff, Emiliano Castellano, Martine De Angelis, Margareta E. Hansson, Stefan Sommer, Jørgen P. Steffensen
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- Journal:
- Annals of Glaciology / Volume 35 / 2002
- Published online by Cambridge University Press:
- 26 June 2018, pp. 299-305
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In the past, ionic analyses of deep ice cores tended to consist of a few widely spaced measurements that indicated general trends in concentration. the ion-chromatographic methods widely used provide well-validated individual data, but are time-consuming. the development of continuous flow analysis (CFA) methods has allowed very rapid, high-resolution data to be collected in the field for a wide range of ions. In the European Project for Ice Coring in Antarctica (EPICA) deep ice-core drilling at Dome C, many ions have been measured at high resolution, and several have been analyzed by more than one method. the full range of ions has been measured in five different laboratories by ion chromatography (IC), at resolutions of 2.5–10 cm. In the field, CFA was used to measure the ions Na+, Ca2+, nitrate and ammonium. Additionally, a new semi-continuous in situ IC method, fast ion chromatography (FIC), was used to analyze sulphate, nitrate and chloride. Some data are now available to 788 m depth. In this paper we compare the data obtained by the three methods, and show that the rapid methods (CFA and FIC) give an excellent indication of trends in ionic data. Differences between the data from the different methods do occur, and in some cases these are genuine, being due to differences in speciation in the methods. We conclude that the best system for most deep ice-core analysis is a rapid system of CFA and FIC, along with in situ meltwater collection for analysis of other ions by IC, but that material should be kept aside for a regular check on analytical quality and for more detailed analysis of some sections.
Trends in proportion of older HIV-infected people in care in Latin America and the Caribbean: a growing challenge
- Y. Caro-Vega, P. F. Belaunzarán-Zamudio, B. Crabtree-Ramírez, B. E. Shepherd, F. Mejia, M. J. Giganti, P. Patterson, B. Grinsztejn, M. Wolff, J. W. Pape, D. Padgett, J. L. Castilho, C. McGowan, J. G. Sierra-Madero
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- Journal:
- Epidemiology & Infection / Volume 146 / Issue 10 / July 2018
- Published online by Cambridge University Press:
- 30 May 2018, pp. 1308-1311
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We aimed to quantify the proportion of people receiving care for HIV-infection that are 50 years or older (older HIV patients) in Latin America and the Caribbean between 2000 and 2015 and to estimate the contribution to the growth of this population of people enrolled before (<50yo) and after 50 years old (yo) (⩾50yo). We used a series of repeated, cross-sectional measurements over time in the Caribbean, Central and South American network (CCASAnet) cohort. We estimated the percentage of patients retained in care each year that were older HIV patients. For every calendar year, we divided patients into two groups: those who enrolled before age 50 and after age 50. We used logistic regression models to estimate the change in the proportion of older HIV patients between 2000 and 2015. The percentage of CCASAnet HIV patients over 50 years had a threefold increase (8% to 24%) between 2000 and 2015. Most of the growth of this population can be explained by the increasing proportion of people that enrolled before 50 years and aged in care. These changes will impact needs of care for people living with HIV, due to multiple comorbidities and high risk of disability associated with aging.
Nitrate in Greenland and Antarctic ice cores: a detailed description of post-depositional processes
- Regine Röthlisberger, Manuel A. Hutterli, Eric W. Wolff, Robert Mulvaney, Hubertus Fischer, Matthias Bigler, Kumiko Goto-Azuma, Margareta E. Hansson, Urs Ruth, Marie-Louise Siggaard-Andersen, Jørgen P. Steffensen
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- Journal:
- Annals of Glaciology / Volume 35 / 2002
- Published online by Cambridge University Press:
- 14 September 2017, pp. 209-216
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A compilation of nitrate (NO3–) data from Greenland has shown that recent NO3– concentrations reveal a temperature dependence similar to that seen in Antarctica. Except for sites with very low accumulation rates, lower temperatures tend to lead to higher NO3– concentrations preserved in the ice. Accumulation rate, which is closely linked to temperature, might influence the concentrations preserved in snow as well, but its effect cannot be separated from the temperature imprint. Processes involved in NO3– deposition are discussed and shown to be temperature- and/or accumulation-rate-dependent. Apart from scavenging of nitric acid (HNO3) during formation of precipitation, uptake of HNO3 onto the ice crystal’s surface during and after precipitation seems to contribute further to the NO3– concentrations found in surface snow. Post-depositional loss of NO3– from the top snow layers is caused by release of HNO3 and by photolysis of NO3–. It is suggested that photolysis accounts for considerable losses at sites with very low accumulation rates. Depending on the site characteristic, and given that the temperature and accumulation-rate dependence is quantified, it should be possible to infer changes in atmospheric HNO3 concentrations.
Sensitivity of chemical species to climatic changes in the last 45 kyr as revealed by high-resolution Dome C (East Antarctica) ice-core analysis
- Roberto Udisti, Silvia Becagli, Silvia Benassai, Martine De Angelis, Margareta E. Hansson, Jean Jouzel, Jacob Schwander, Jørgen P. Steffensen, Rita Traversi, Eric Wolff
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- Journal:
- Annals of Glaciology / Volume 39 / 2004
- Published online by Cambridge University Press:
- 14 September 2017, pp. 457-466
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To assess the cause/effect relationship between climatic and environmental changes, we report high-resolution chemical profiles of the Dome C ice core (788m, 45 kyr), drilled in the framework of the European Project for Ice Coring in Antarctica (EPICA). Snow-concentration and depositional-flux changes during the last deglaciation were compared with climatic changes, derived by δD profile. Concentration and temperature profiles showed an anticorrelation, driven by changes in source intensity and transport efficiency of the atmospheric aerosol and by snow accumulation-rate variations. The flux calculation allowed correction for accumulation rate. While sulphate and ammonium fluxes are quite constant, Na+, Mg2+ and Ca2+ underwent the greatest changes, showing fluxes respectively about two, three and six times lower in the Holocene than in the Last Glacial Maximum. Chloride, nitrate and methanesulphonic acid (MSA) also exhibited large changes, but their persistence depends on depositional and post-depositional effects. The comparison between concentrations and δD profiles revealed leads and lags between chemical and temperature trends: Ca2+ and nitrate preceded by about 300 years the δD increase at the deglaciation onset, while MSA showed a 400 year delay. Generally, all components reached low Holocene values in the first deglaciation step (18.0–14.0 kyr BP), but Na+, Mg2+ and nitrate show changes during the Antarctic Cold Reversal (14.0– 12.5 kyr BP).
Snow chemistry across Antarctica
- N. Bertler, P.A. Mayewski, A. Aristarain, P. Barrett, S. Becagli, R. Bernardo, S. Bo, Xiao C., M. Curran, Qin D., D. Dixon, F. Ferrona, H. Fischer, M. Frey, M. Frezzotti, F. Fundel, C. Genthon, R. Gragnani, G. Hamilton, M. Handley, S. Hong, E. Isaksson, Kang J., Ren J., K. Kamiyama, S. Kanamori, E. Kärkäs, L. Karlöf, S. Kaspari, K. Kreutz, E. Meyerson, A. Kurbatov, Y. Ming, Zhang M., H. Motoyama, R. Mulvaney, H. Oerter, E. Osterberg, M. Proposito, A. Pyne, U. Ruth, J. Simões, B. Smith, S. Sneed, K. Teinilä, F. Traufetter, R. Udisti, A. Virkkula, O. Watanabe, B. Williamson, J-G. Winther, Li Y., E. Wolff, Li Z., A. Zielinski
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- Journal:
- Annals of Glaciology / Volume 41 / 2005
- Published online by Cambridge University Press:
- 14 September 2017, pp. 167-179
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An updated compilation of published and new data of major-ion (Ca, Cl, K, Mg, Na, NO3, SO4) and methylsulfonate (MS) concentrations in snow from 520 Antarctic sites is provided by the national ITASE (International Trans-Antarctic Scientific Expedition) programmes of Australia, Brazil, China, Germany, Italy, Japan, Korea, New Zealand, Norway, the United Kingdom, the United States and the national Antarctic programme of Finland. The comparison shows that snow chemistry concentrations vary by up to four orders of magnitude across Antarctica and exhibit distinct geographical patterns. The Antarctic-wide comparison of glaciochemical records provides a unique opportunity to improve our understanding of the fundamental factors that ultimately control the chemistry of snow or ice samples. This paper aims to initiate data compilation and administration in order to provide a framework for facilitation of Antarctic-wide snow chemistry discussions across all ITASE nations and other contributing groups. The data are made available through the ITASE web page (http://www2.umaine.edu/itase/content/syngroups/snowchem.html) and will be updated with new data as they are provided. In addition, recommendations for future research efforts are summarized.
Capture and scanning electron microscopy of individual snow crystals
- E. W. Wolff, A. P. Reid
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- Journal of Glaciology / Volume 40 / Issue 134 / 1994
- Published online by Cambridge University Press:
- 20 January 2017, pp. 195-197
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A snow crystal has been successfully collected on to a scanning electron microscope (SEM) stub in central Greenland. It was preserved at liquid-nitrogen temperature for 5 months, prior to examination in the SEM. This is believed to be the first time a snow crystal has been observed directly in the SEM and offers some new experimental methods for understanding crystals and their chemistry.
Development of paediatric electrophysiology standards for Florida Children’s Medical Services
- Jorge McCormack, Stephen Seslar, Grace Wolff, Ming Young, Randall Bryant, Rodrigo Neghme, Steven Fishberger, Jamie A. Decker, Mary Sokoloski, Jason Ho, David Lawrence, Chrishonda Jenkins, Kelli Stannard, Gerold L. Schiebler, William Blanchard, Jeffrey P. Jacobs
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- Journal:
- Cardiology in the Young / Volume 24 / Issue 6 / December 2014
- Published online by Cambridge University Press:
- 29 December 2014, pp. 1134-1149
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The Florida Children’s Medical Services (CMS) has a long-standing history of ensuring that providers of multiple paediatric subspecialties abide by the highest standards. The cardiac sub-committee has written quality standard documents that participating programmes must meet or exceed. These standards oversee paediatric cardiology services including surgery, catheterisations, and outpatient services. On April, 2012, the cardiac sub-committee decided to develop similar standards in paediatric electrophysiology. A task force was created and began this process. These standards include a catalogue of required and optional equipment, as well as staff and physician credentials. We sought to establish expectations of procedural numbers by practitioner and facility. The task force surveyed the members of the Pediatric and Congenital Electrophysiology Society. Finding no consensus, the task force is committed to generate the data by requiring that the CMS participating programmes enrol and submit data to the Multicenter Pediatric and Adult Congenital EP Quality (MAP-IT™) Initiative. This manuscript details the work of the Florida CMS Paediatric Electrophysiology Task Force.
Contingent Capital: The Case of COERCs
- George Pennacchi, Theo Vermaelen, Christian C. P. Wolff
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- Journal:
- Journal of Financial and Quantitative Analysis / Volume 49 / Issue 3 / June 2014
- Published online by Cambridge University Press:
- 08 July 2014, pp. 541-574
- Print publication:
- June 2014
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This paper introduces and analyzes a new form of contingent convertible: a call option enhanced reverse convertible (COERC). If an issuing bank’s market value of capital breaches a trigger, COERCs convert to many new equity shares that would heavily dilute existing shareholders, except that shareholders have the option to purchase these shares at the bond’s par value. COERCs have low risk: They are almost always fully repaid in cash. Yet, they reduce government bailouts by replenishing a bank’s capital. COERCs’ design also avoids problems with market-value triggers, such as manipulation or panic, while reducing moral hazard and debt overhang.
Local food environments are associated with girls’ energy, sugar-sweetened beverage and snack-food intakes
- Andrea L Deierlein, Maida P Galvez, Irene H Yen, Susan M Pinney, Frank M Biro, Lawrence H Kushi, Susan Teitelbaum, Mary S Wolff
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- Journal:
- Public Health Nutrition / Volume 17 / Issue 10 / October 2014
- Published online by Cambridge University Press:
- 12 May 2014, pp. 2194-2200
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Objective
To describe availability and frequency of use of local snack-food outlets and determine whether reported use of these outlets was associated with dietary intakes.
DesignData were cross-sectional. Availability and frequency of use of three types of local snack-food outlets were reported. Daily dietary intakes were based on the average of up to four 24 h dietary recalls. Multivariable linear regression models estimated average daily intakes of energy, sugar-sweetened beverages (SSB) and snack foods/sweets associated with use of outlets.
SettingMulti-site, observational cohort study in the USA, 2004–2006.
SubjectsGirls aged 6–8 years (n 1010).
ResultsWeekly frequency of use of local snack-food outlets increased with number of available types of outlets. Girls with access to only one type of outlet reported consuming food/beverage items less frequently than girls with access to two or three types of outlets (P <0·001). Girls’ daily energy, SSB and snack foods/sweets intakes increased with greater use of outlets. Girls who reported using outlets>1 to 3 times/week consumed 0·27 (95 % CI 0·13, 0·40) servings of SSB more daily than girls who reported no use. Girls who reported using outlets>3 times/week consumed 449·61 (95 % CI 134·93, 764·29) kJ, 0·43 (95 % CI 0·29, 0·58) servings of SSB and 0·38 (95 % CI 0·12, 0·65) servings of snack foods/sweets more daily than those who reported no use.
ConclusionsGirls’ frequency of use of local snack-food outlets increases with the number of available types of outlets and is associated with greater daily intakes of energy and servings of SSB and snack foods/sweets.
Cost drivers of inpatient mental health care: a systematic review
- J. Wolff, P. McCrone, L. Koeser, C. Normann, A. Patel
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- Journal:
- Epidemiology and Psychiatric Sciences / Volume 24 / Issue 1 / February 2015
- Published online by Cambridge University Press:
- 16 December 2013, pp. 78-89
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Aims.
New reimbursement schemes for inpatient mental health care are imminent in the UK and Germany. The shared intention is to reflect cost differences between patients in reimbursement rates. This requires understanding of patient characteristics that influence hospital resource use. The aim of this review was to show which associations between mental health care per diem hospital costs and patient characteristics are supported by current evidence.
Methods.A systematic review of the literature published between 1980 and 2012 was carried out. The search strategy included electronic databases and hand-searching. Furthermore, reference lists, citing articles and related publications were screened and experts were contacted.
Results.The search found eight studies. Dispersion in per diem costs was moderate, as was the ability to explain it with patient characteristics. Six patient characteristics were identified as the most relevant variables. These were (1) age, (2) major diagnostic group, (3) risk, (4) legal problems, (5) the ability to perform activities of daily living and (6) presence of psychotic or affective symptoms. Two non-patient-related factors were identified. These were (1) day of stay and (2) treatment site.
Conclusions.Idiosyncrasies of mental health care complicated the prediction of per diem hospital costs. More research is required in European settings since transferability of results is unlikely.
Notes on the contributors
- Edited by Yo Tomita, Queen's University Belfast, Robin A. Leaver, Queen's University Belfast, Jan Smaczny, Queen's University Belfast
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- Book:
- Exploring Bach's B-minor Mass
- Published online:
- 05 October 2013
- Print publication:
- 17 October 2013, pp xv-xviii
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3 - How has climate responded to natural perturbations?
- Edited by Sarah E. Cornell, I. Colin Prentice, Macquarie University, Sydney, Joanna I. House, University of Bristol, Catherine J. Downy, European Space Agency
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- Understanding the Earth System
- Published online:
- 05 November 2012
- Print publication:
- 09 August 2012, pp 72-101
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Summary
In this chapter, we describe and explain some of the patterns observed in the behaviour of Earth’s climate system. We explain some of the causes of the climate’s natural variability, setting contemporary climate change in its longer-term context. We describe the various lines of evidence about climate forcing and the feedbacks that determine the responses to perturbations, and the way in which reconstructions of past climates can be used in combination with models and contemporary observations of change.
Introduction
Human activity is creating a major perturbation to the Earth, directly affecting the composition of the atmosphere, and the nature of the land surface . These direct effects are expected in turn to cause impacts on numerous aspects of the Earth: regional climates , the distribution of ice and vegetation types, and perhaps the circulation of the oceans. Numerous interactions within the Earth system must be understood to enable prediction of the effects of the imposed changes. Models used for prediction are underpinned by a physical understanding of the climate. Aspects of these models are generally tuned to the Earth we experience today, but it is their representation of Earth’s response to change that really interests us.
By observing the Earth, both directly in the present and indirectly in the past, we learn about processes and feedbacks that models need to represent; and we can test whether the real Earth has responded to perturbations with the speed and magnitude that our models display. The ultimate goal is to use such observations to test models quantitatively, and to calibrate some of their less-constrained parameters. This goal cannot be fully realized unless we have knowledge of both the perturbation and the spatial pattern and magnitude of the response. This chapter concentrates on observations of how the Earth’s climate has responded to perturbations in the past.
L1-SMOOTHING FOR THE ORNSTEIN–UHLENBECK SEMIGROUP
- Part of
- K. Ball, F. Barthe, W. Bednorz, K. Oleszkiewicz, P. Wolff
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- Journal:
- Mathematika / Volume 59 / Issue 1 / January 2013
- Published online by Cambridge University Press:
- 02 August 2012, pp. 160-168
- Print publication:
- January 2013
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Given a probability density, we estimate the rate of decay of the measure of the level sets of its evolutes by the Ornstein–Uhlenbeck semigroup. The rate is faster than what follows from the preservation of mass and Markov’s inequality.
ENVIRONMENTAL REVIEW & CASE STUDY: Reviewing NEPA's Past: Improving NEPA's Future
- Roger P. Hansen, Theodore A. Wolff
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- Journal:
- Environmental Practice / Volume 13 / Issue 3 / September 2011
- Published online by Cambridge University Press:
- 14 September 2011, pp. 235-249
- Print publication:
- September 2011
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On December 31, 2009, President Barack Obama proclaimed the 40th anniversary of the National Environmental Policy Act of 1969 (NEPA), a landmark “conservation” law. During this 40-year period, NEPA has been hailed as a champion of American “environmental rights” and criticized as an obstacle to economic progress. In the view of some critics, NEPA uselessly exploits private and public time and resources. It is remarkable that NEPA, although battered and worn, has survived virtually intact for four decades. This article is not a “how to” dissertation containing new or revised prescriptions for preparing defendable environmental impact statements (EISs), environmental assessments (EAs), and other action-forcing documents prepared by federal agencies. It is not a recitation of main provisions in the NEPA [National Environmental Policy Act of 1969] with which most readers are familiar. Instead, it selects 10 of a plethora of problems blockading responsible NEPA process implementation: seven historic and persistent and three new or emerging. This selection is by no means an all-inclusive list. Finally, the article reviews NEPA's development and looks to some future steps that might be taken to implement NEPA as its founders intended.
Environmental Practice 13:235–249 (2011)
Infection and immunity for human parvovirus B19 in patients with febrile exanthema
- M. S. PEDRANTI, P. BARBERO, C. WOLFF, L. M. GHIETTO, M. ZAPATA, M. P. ADAMO
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- Journal:
- Epidemiology & Infection / Volume 140 / Issue 3 / March 2012
- Published online by Cambridge University Press:
- 18 May 2011, pp. 454-461
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The contribution of parvovirus B19 (B19V) as a causative agent of febrile exanthema (FE) in Cordoba, Argentina, was analysed by detection of viral DNA, and specific IgM and IgG. Serum from 141 patients with FE who were negative for measles and rubella, collected during 2005–2009, plus serum from 31 healthy individuals, were assayed. B19V was the aetiological agent in 14·9% of all FE cases, and in 39·1% in an epidemic year (2007). B19V DNA was detected in 47·6% of IgM-positive FE patients, 30·2% of IgM-negative/IgG-positive FE patients, and 9·7% of healthy controls, indicating B19V long-term infection in ~10% of immunocompetent individuals. Persistent B19V DNA was significantly more frequent in children than adults and in males than females. All patients with acute B19V infection had rash and fever, 85·7% had adenopathy, and only 14·3% had arthropathy. This is the first follow-up study of markers of infection and immunity for B19V infection in Argentina.
Contributors
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- By Rose Teteki Abbey, K. C. Abraham, David Tuesday Adamo, LeRoy H. Aden, Efrain Agosto, Victor Aguilan, Gillian T. W. Ahlgren, Charanjit Kaur AjitSingh, Dorothy B E A Akoto, Giuseppe Alberigo, Daniel E. Albrecht, Ruth Albrecht, Daniel O. Aleshire, Urs Altermatt, Anand Amaladass, Michael Amaladoss, James N. Amanze, Lesley G. Anderson, Thomas C. Anderson, Victor Anderson, Hope S. Antone, María Pilar Aquino, Paula Arai, Victorio Araya Guillén, S. Wesley Ariarajah, Ellen T. Armour, Brett Gregory Armstrong, Atsuhiro Asano, Naim Stifan Ateek, Mahmoud Ayoub, John Alembillah Azumah, Mercedes L. García Bachmann, Irena Backus, J. Wayne Baker, Mieke Bal, Lewis V. Baldwin, William Barbieri, António Barbosa da Silva, David Basinger, Bolaji Olukemi Bateye, Oswald Bayer, Daniel H. Bays, Rosalie Beck, Nancy Elizabeth Bedford, Guy-Thomas Bedouelle, Chorbishop Seely Beggiani, Wolfgang Behringer, Christopher M. Bellitto, Byard Bennett, Harold V. Bennett, Teresa Berger, Miguel A. Bernad, Henley Bernard, Alan E. Bernstein, Jon L. Berquist, Johannes Beutler, Ana María Bidegain, Matthew P. Binkewicz, Jennifer Bird, Joseph Blenkinsopp, Dmytro Bondarenko, Paulo Bonfatti, Riet en Pim Bons-Storm, Jessica A. Boon, Marcus J. Borg, Mark Bosco, Peter C. Bouteneff, François Bovon, William D. Bowman, Paul S. Boyer, David Brakke, Richard E. Brantley, Marcus Braybrooke, Ian Breward, Ênio José da Costa Brito, Jewel Spears Brooker, Johannes Brosseder, Nicholas Canfield Read Brown, Robert F. Brown, Pamela K. Brubaker, Walter Brueggemann, Bishop Colin O. Buchanan, Stanley M. Burgess, Amy Nelson Burnett, J. Patout Burns, David B. Burrell, David Buttrick, James P. Byrd, Lavinia Byrne, Gerado Caetano, Marcos Caldas, Alkiviadis Calivas, William J. Callahan, Salvatore Calomino, Euan K. Cameron, William S. Campbell, Marcelo Ayres Camurça, Daniel F. Caner, Paul E. Capetz, Carlos F. Cardoza-Orlandi, Patrick W. Carey, Barbara Carvill, Hal Cauthron, Subhadra Mitra Channa, Mark D. Chapman, James H. Charlesworth, Kenneth R. Chase, Chen Zemin, Luciano Chianeque, Philip Chia Phin Yin, Francisca H. Chimhanda, Daniel Chiquete, John T. Chirban, Soobin Choi, Robert Choquette, Mita Choudhury, Gerald Christianson, John Chryssavgis, Sejong Chun, Esther Chung-Kim, Charles M. A. Clark, Elizabeth A. Clark, Sathianathan Clarke, Fred Cloud, John B. Cobb, W. Owen Cole, John A Coleman, John J. Collins, Sylvia Collins-Mayo, Paul K. Conkin, Beth A. Conklin, Sean Connolly, Demetrios J. Constantelos, Michael A. Conway, Paula M. Cooey, Austin Cooper, Michael L. Cooper-White, Pamela Cooper-White, L. William Countryman, Sérgio Coutinho, Pamela Couture, Shannon Craigo-Snell, James L. Crenshaw, David Crowner, Humberto Horacio Cucchetti, Lawrence S. Cunningham, Elizabeth Mason Currier, Emmanuel Cutrone, Mary L. Daniel, David D. Daniels, Robert Darden, Rolf Darge, Isaiah Dau, Jeffry C. Davis, Jane Dawson, Valentin Dedji, John W. de Gruchy, Paul DeHart, Wendy J. Deichmann Edwards, Miguel A. De La Torre, George E. Demacopoulos, Thomas de Mayo, Leah DeVun, Beatriz de Vasconcellos Dias, Dennis C. Dickerson, John M. Dillon, Luis Miguel Donatello, Igor Dorfmann-Lazarev, Susanna Drake, Jonathan A. Draper, N. Dreher Martin, Otto Dreydoppel, Angelyn Dries, A. J. Droge, Francis X. D'Sa, Marilyn Dunn, Nicole Wilkinson Duran, Rifaat Ebied, Mark J. Edwards, William H. Edwards, Leonard H. Ehrlich, Nancy L. Eiesland, Martin Elbel, J. Harold Ellens, Stephen Ellingson, Marvin M. Ellison, Robert Ellsberg, Jean Bethke Elshtain, Eldon Jay Epp, Peter C. Erb, Tassilo Erhardt, Maria Erling, Noel Leo Erskine, Gillian R. Evans, Virginia Fabella, Michael A. Fahey, Edward Farley, Margaret A. Farley, Wendy Farley, Robert Fastiggi, Seena Fazel, Duncan S. Ferguson, Helwar Figueroa, Paul Corby Finney, Kyriaki Karidoyanes FitzGerald, Thomas E. FitzGerald, John R. Fitzmier, Marie Therese Flanagan, Sabina Flanagan, Claude Flipo, Ronald B. 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Yee, Viktor Yelensky, Yeo Khiok-Khng, Gustav K. K. Yeung, Angela Yiu, Amos Yong, Yong Ting Jin, You Bin, Youhanna Nessim Youssef, Eliana Yunes, Robert Michael Zaller, Valarie H. Ziegler, Barbara Brown Zikmund, Joyce Ann Zimmerman, Aurora Zlotnik, Zhuo Xinping
- Edited by Daniel Patte, Vanderbilt University, Tennessee
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- The Cambridge Dictionary of Christianity
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- 05 August 2012
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- 20 September 2010, pp xi-xliv
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Use of the India-ink Immuno-reaction for the rapid detection of enteric pathogens in two areas of Nigeria
- G. Ternak, M. Wolff, D. P. Britt
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- Journal of Hygiene / Volume 87 / Issue 3 / December 1981
- Published online by Cambridge University Press:
- 25 March 2010, pp. 493-499
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The India-ink Immuno-reaction (IIR) was used as a simple, convenient procedure for the detection of carriers of enteric organisms in an unselected sample of patients attending a mission clinic at Kubacha in a remote area of Kaduna State, northern Nigeria. To assess the reliability of this procedure in difficult working conditions a similar population from the same clinic was subsequently examined by routine bacteriological culture techniques. Because of a temporary shortage of suitable anti-sera we were unable also to examine specimens from this second group by IIR.
A further group of patients attending the out-patients clinic of the General Hospital in Kaduna with symptoms of acute enteric disease was investigated using both IIR and routine culture.
Proportionally more positive results were obtained for Salmonellae, Shigellae and Vibrios with IIR than with routine culture. A larger scale controlled survey is desirable to evaluate the procedure further.
Analysis of regional congenital cardiac surgical outcomes in Florida using The Society of Thoracic Surgeons Congenital Heart Surgery Database
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- Jeffrey P. Jacobs, James A. Quintessenza, Redmond P. Burke, Mark S. Bleiweis, Barry J. Byrne, Eric L. Ceithaml, William M. DeCampli, Jorge M. Giroud, Richard A. Perryman, Eliot R. Rosenkranz, Grace Wolff, Vicki Posner, Sue Steverson, William B. Blanchard, Gerry L. Schiebler
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- Cardiology in the Young / Volume 19 / Issue 4 / August 2009
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- 01 August 2009, pp. 360-369
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Background
Florida is the fourth largest state in the United States of America. In 2004, 218,045 live babies were born in Florida, accounting for approximately 1744 new cases of congenital heart disease. We review the initial experience of The Society of Thoracic Surgeons Congenital Heart Surgery Database with a regional outcomes report, namely the Society of Thoracic Surgeons Florida Regional Report.
MethodsEight centres in Florida provide services for congenital cardiac surgery. The Children’s Medical Services of Florida provide a framework for quality improvement collaboration between centres. All congenital cardiac surgical centres in Florida have voluntarily agreed to submit data to the Society of Thoracic Surgeons Database. The Society of Thoracic Surgeons and Duke Clinical Research Institute prepared a Florida Regional Report to allow detailed regional analysis of outcomes for congenital cardiac surgery.
ResultsThe report of 2007 from the Society of Thoracic Surgeons Congenital Heart Surgery Database includes details of 61,014 operations performed during the 4 year data harvest window, which extended from 2003 through 2006. Of these operations, 6,385 (10.5%) were performed in Florida. Discharge mortality in the data from Florida overall, and from each Florida site, with 95% confidence intervals, is not different from cumulative data from the entire Society of Thoracic Surgeons Database, both for all patients and for patients stratified by complexity.
ConclusionsA regional consortium of congenital heart surgery centres in Florida under the framework of the Children’s Medical Services has allowed for inter-institutional collaboration with the goal of quality improvement. This experience demonstrates, first, that the database maintained by the Society of Thoracic Surgeons can provide the framework for regional analysis of outcomes, and second, that voluntary regional collaborative efforts permit the pooling of data for such analysis.