This article examines the intersection between forced labour, supply chain risks and environmental, social and governance concerns that pose a threat to the ‘Just Transition’. It addresses how states, businesses and other stakeholders drive or fail Just Transitions and why. Through an application of a ‘policy currents framework’ to the case study of solar panel supply chains originating in China, we analyse states, international organisations and civil society organisations’ framing of modern slavery issues in the context of the ‘Just Transition’. We focus on the framing of challenges and solutions to the nexus of forced labour and climate change. We draw attention to the fact decarbonisation risks are being achieved at the cost of labour rights abuses within supply chains, question whether the concept of renewable sources is ‘Just’ and provide a series of recommendations for stakeholders.

Film offers untapped potential for making critical interventions in world politics, particularly in ways that harness people’s capacity to narrate stories that creatively empower their communities. Combining International Relations scholarship on visual politics with narrative theory and feminist scholarship on care, this paper presents film as a means of exploring and expressing narrative agency; that is, the power to tell stories that represent people’s experiences in ways that disrupt hegemonic narratives. Dialectics of care and narrative agency are explored in the context of military-to-civilian ‘transition’ in Britain. We argue that the landscape of transition for military veterans is dominated by a preoccupation with employment and economic productivity, resulting in a ‘care deficit’ for veterans leaving the military. Through the Stories in Transition project, which used co-created film to explore narrative agency in the context of three veterans’ charities, we argue that the act of making care visible constitutes a necessary intervention in this transitional landscape. Grounding this intervention within feminist care ethics and the related notion of care aesthetics, we highlight the potential for film to reveal in compelling audio-visual narratives an alternative project of transition which might better sustain life and hope in the aftermath of military service.

A topic of recent interest involves the nature of theistic faith, and in particular, the boundaries of such faith. For example, philosophers have taken opposing positions on whether atheists and agnostics can have theistic faith. I consider a related question: whether anti-theists, who think God’s existence would be a bad thing, can have faith. I argue for a negative answer, although with several caveats.

Objectives/Goals: This study will integrate scientific evidence to create messaging about the modifiable risk factors for Alzheimer’s disease (AD) and examine how culturally tailoring elements in message content, such as text and visualizations in infographic messaging, impacts cognitive processing of AD prevention messages among Black adults. Methods/Study Population: This study is guided by the two-dimensional theory of cultural sensitivity and the elaboration likelihood model (ELM). The two-dimensional theory distinguishes between surface structure (visualizations) and deep structure (text with embedded cultural features) in messaging. The ELM considers how message attributes influence cognitive processing. A 2 × 2 factorial experiment will test the impact of cultural features (surface vs. deep) and message type (text-based vs. infographic) on persuasive outcomes regarding modifying AD risk factors. Black adults will be recruited from local churches and randomly assigned to one of four conditions, after which they will complete post-test measures. Statistical analyses will determine the effects of cultural tailoring and message effects on outcome variables. Results/Anticipated Results: Guided by previous literature (Resnicow et al., 1999; Lazard & Atkinson, 2015; Lam et al., 2022), we hypothesize an interaction effect of cultural tailoring and message type, wherein surface structure infographic messages and deep structure text-based messages will outperform the other two message conditions, resulting in greater cognitive processing and more positive attitudes and behavioral intentions toward modifying AD risk factors. In addition, a research question asks whether there will be differences between surface structure infographic messages and deep structure text-based messages on outcome variables. The study will advance understanding of the effects of cultural sensitivity and visual vs. text-based messaging by integrating these literatures. Discussion/Significance of Impact: This research will contribute to the literature on culturally tailored health messages and persuasive effects of text vs. visual messages. The findings can inform the development of more effective, culturally relevant public health campaigns for AD prevention by reducing risk for AD through modifiable risk factors in diverse populations.

We study the descriptive complexity of sets of points defined by restricting the statistical behaviour of their orbits in dynamical systems on Polish spaces. Particular examples of such sets are the sets of generic points of invariant Borel probability measures, but we also consider much more general sets (for example, $\alpha $-Birkhoff regular sets and the irregular set appearing in the multifractal analysis of ergodic averages of a continuous real-valued function). We show that many of these sets are Borel in general, and all these are Borel when we assume that our space is compact. We provide examples of these sets being non-Borel, properly placed at the first level of the projective hierarchy (they are complete analytic or co-analytic). This proves that the compactness assumption is, in some cases, necessary to obtain Borelness. When these sets are Borel, we measure their descriptive complexity using the Borel hierarchy. We show that the sets of interest are located at most at the third level of the hierarchy. We also use a modified version of the specification property to show that these sets are properly located at the third level of the hierarchy for many dynamical systems. To demonstrate that the specification property is a sufficient, but not necessary, condition for maximal descriptive complexity of a set of generic points, we provide an example of a compact minimal system with an invariant measure whose set of generic points is $\boldsymbol {\Pi }^0_3$-complete.

This study explored the effects of different human milk oligosaccharides (HMOs), solely and in combination, on gut microbiota composition and metabolic activity (organic acid production), using anaerobic in vitro batch culture fermenters. The aim was to compare prebiotic effects of HMOs (2’FL, 3’FL, 3’SL, 6’SL, LNT, LNnT, and 1:1 ratio mixes of 2’FL/3’SL and 3’SL/LNT) in faecal samples from irritable bowel syndrome (IBS) donors and healthy controls, and to determine the best-performing HMO in IBS. Fluorescent in situ hybridisation coupled with flow cytometry was utilised to study microbiota changes in major colonic genera, and organic acid production was assessed by gas chromatography. IBS donors had different starting microbial profiles compared to healthy controls and lower levels of organic acids. In response to HMOs, there were alterations in both the control and IBS faecal microbiomes. In IBS donor fermenters, Bifidobacterium, Faecalibacterium, total bacterial numbers, and organic acid production significantly increased post-HMO intervention. When comparing the effect of HMO interventions on the microbiota and organic acid production, a mix of 3’SL/LNT HMOs may be the most promising intervention for IBS patients.

It is still an open question when groups perform better than individuals in intellective tasks. We report that in an Acquiring a Company game, what prevailed when there was disagreement among group members was the median proposal and not the best proposal. This aggregation rule explains why groups underperformed with respect to a “truth wins” benchmark and why they performed better than individuals deciding in isolation in a simple version of the task but worse in the more difficult version. Implications are drawn on when to employ groups rather than individuals in decision making.

This study aimed to assess Well-Being Index scores in paediatric cardiac ICU (PCICU) registered nurses and advanced practice providers. Secondary objectives included identifying factors correlating with at-risk Well-Being Index scores and exploring predictors of these scores, with attention to the impact of the coronavirus disease 2019 pandemic. A multicentre electronic survey was conducted between October 2021 and January 2022. Registered nurses and advanced practice providers working in PCICUs at US centres participating in the Collaborative Research from the Pediatric Cardiac Intensive Care Society were included.

The survey included the nine-item Well-Being Index and questions about demographics and factors influencing well-being, such as coronavirus disease 2019. The Well-Being Index is a validated tool to predict workforce distress and well-being. Out of 218 participants (180 registered nurses, 38 advanced practice providers), 137 registered nurses (76%) and 15 advanced practice providers (39%) had at-risk Well-Being Index scores. A total of 61% of nurses and 34% of advanced practice providers reported an intent to leave. Intent to leave was significantly linked to lower well-being for registered nurses (p = 0.002). Leadership support reduced registered nurses’ distress risk by 68% compared to no support (p = 0.04). Increased stress since coronavirus disease 2019 raised registered nurses’ poor well-being risk by four times (p = 0.001). PCICU registered nurses and advanced practice providers are at risk for poor well-being, exacerbated by the pandemic. Those with poor well-being may be more likely to leave. Leadership support is vital for nurses’ well-being. Further research is needed to establish baseline well-being.

Of 313 patients whose outpatient parenteral antimicrobial therapy was managed by an ID physician, only 39 [12.5%, 95% CI (8.8%–16.1%)] had clinical decisions influenced by erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), or both. ESR/CRP ordering was associated with $530 in excess cost per treatment course (average duration 5.1 weeks) representing a diagnostic stewardship opportunity.

Joseph Addison’s Cato (1713) is a play in the US-American bloodstream: it was quoted repeatedly by the architects of the American Revolution and was famously performed by Washington’s troops at Valley Forge in 1778. But what does this 300-year-old verse tragedy—with its entangled political, racial, and theatrical histories and implications—have to say to audiences in the present-day US South at the Clarence Brown Theatre, Tennessee, in 2023?

We present the first nonlinear results on the problem of non-rotating thermal convection in an internally heated full sphere. A nonlinear stability analysis by the energy method yields that, at least for no-slip boundary conditions, the critical Rayleigh numbers for linear stability and nonlinear stability coincide. We then explore different ranges of the parameter regime using direct numerical simulations. We first report on the system behaviour for a fixed Prandtl number of unity and both stress-free and no-slip boundary conditions up to very high forcing, reaching Rayleigh number $Ra=2\times 10^{12}$, approximately 250 million times the critical value ($Ra_c$) for the onset of convection under no-slip conditions. For both boundary conditions, we observe a scaling for the advective heat transfer measured by the Nusselt number $Nu$ close to $Nu \sim Ra^{1/4}$. This is consistent with a scaling prediction that we formulate analogously to the classical scaling in Rayleigh–Bénard convection. We then investigate the Prandtl number dependence at low to intermediate forcing for stress-free boundary conditions in the ranges $0.1 \leq Pr \leq 30$ and $Ra_c=3091\leq Ra \leq 3\times 10^5 \approx 100Ra_c$. We find five distinct dynamical regimes depending on the Prandtl number, describe each regime individually and issue heuristic interpretations of the system behaviour where possible.

In 2003, Ozsváth, Szabó and Rasmussen introduced the $\tau $ invariant for knots, and in 2011, Sarkar [‘Grid diagrams and the Ozsváth–Szabó tau-invariant’, Math. Res. Lett. 18(6) (2011), 1239–1257] published a computational shortcut for the $\tau $ invariant of knots that can be represented by diagonal grid diagrams. Previously, the only knots known to have diagonal grid diagram representations were torus knots. We prove that all such knots are positive knots and we produce an example of a knot with a diagonal grid diagram representation which is not a torus knot.

The interaction between national constitutions and transnational sources of law (foreign and international) has generated quite an active disagreement in the United States about what these bodies of law have to do with each other. This paper will explore these debates and the postures towards transnational law and its role in domestic constitutional adjudication which they express. It will identify three postures — of convergence, of resistance, and of engagement — that are manifest in the opinions of different justices of important high courts around the world, and will argue for a posture of ‘engagement’ at least in established constitutional systems like that of the United States.