36 results
A mixed-methods analysis of patient safety incidents involving opioid substitution treatment with methadone or buprenorphine in community-based care in England and Wales
- R. Gibson, N. Macleod, L. Donaldson, H. Williams, A. Sheikh, A. Carson-Stevens
-
- Journal:
- European Psychiatry / Volume 64 / Issue S1 / April 2021
- Published online by Cambridge University Press:
- 13 August 2021, p. S558
-
- Article
-
- You have access Access
- Open access
- Export citation
-
Introduction
There is a paucity of knowledge and understanding of medical error in opioid substitution treatment programmes.
ObjectivesTo characterise patient safety incidents involving opioid-substitution treatment with methadone or buprenorphine in community-based care to identify the sources and nature of harm, describe and interpret themes and use this qualitative analysis to identify priorities to focus future improvement work.
MethodsWe undertook a mixed-methods study examining incidents involving opioid substitution treatment with methadone or buprenorphine in community-based care submitted between 2005 and 2015 from the National Reporting and Learning System, a repository of incident reports from England and Wales. We analysed each report using four frameworks to identify incident type, contributory factors, incident outcome and severity of harm. Analysis involved detailed data coding and iterative generation of data summaries using descriptive statistical and thematic analysis.
Results2,284 reports were identified. We found that most risks of harm came from failure in one of four processes of care delivery: prescribing opiate-substitution (n=151); supervised dispensing errors (n=248); non-supervised dispensing errors (n=318); and monitoring and communication activities (n=1544). Most incidents resulting in harm involved supervised or non-supervised dispensing (n=91/127, 72%). Staff- (e.g. mistakes, not following protocols) and organisation-related (e.g. poor working conditions or poor continuity of care between services) contributory factors were present for over half of incidents.
ConclusionsWe have identified four processes of care delivery and associated contributory factors, which represent potential target areas for healthcare systems worldwide to develop interventions to improve the safe delivery of opioid substitution treatment.
Invited review: A position on the Global Livestock Environmental Assessment Model (GLEAM)
- M. J. MacLeod, T. Vellinga, C. Opio, A. Falcucci, G. Tempio, B. Henderson, H. Makkar, A. Mottet, T. Robinson, H. Steinfeld, P. J. Gerber
-
- Article
-
- You have access Access
- HTML
- Export citation
-
The livestock sector is one of the fastest growing subsectors of the agricultural economy and, while it makes a major contribution to global food supply and economic development, it also consumes significant amounts of natural resources and alters the environment. In order to improve our understanding of the global environmental impact of livestock supply chains, the Food and Agriculture Organization of the United Nations has developed the Global Livestock Environmental Assessment Model (GLEAM). The purpose of this paper is to provide a review of GLEAM. Specifically, it explains the model architecture, methods and functionality, that is the types of analysis that the model can perform. The model focuses primarily on the quantification of greenhouse gases emissions arising from the production of the 11 main livestock commodities. The model inputs and outputs are managed and produced as raster data sets, with spatial resolution of 0.05 decimal degrees. The Global Livestock Environmental Assessment Model v1.0 consists of five distinct modules: (a) the Herd Module; (b) the Manure Module; (c) the Feed Module; (d) the System Module; (e) the Allocation Module. In terms of the modelling approach, GLEAM has several advantages. For example spatial information on livestock distributions and crops yields enables rations to be derived that reflect the local availability of feed resources in developing countries. The Global Livestock Environmental Assessment Model also contains a herd model that enables livestock statistics to be disaggregated and variation in livestock performance and management to be captured. Priorities for future development of GLEAM include: improving data quality and the methods used to perform emissions calculations; extending the scope of the model to include selected additional environmental impacts and to enable predictive modelling; and improving the utility of GLEAM output.
The Australian Square Kilometre Array Pathfinder: Performance of the Boolardy Engineering Test Array
- Part of
- D. McConnell, J. R. Allison, K. Bannister, M. E. Bell, H. E. Bignall, A. P. Chippendale, P. G. Edwards, L. Harvey-Smith, S. Hegarty, I. Heywood, A. W. Hotan, B. T. Indermuehle, E. Lenc, J. Marvil, A. Popping, W. Raja, J. E. Reynolds, R. J. Sault, P. Serra, M. A. Voronkov, M. Whiting, S. W. Amy, P. Axtens, L. Ball, T. J. Bateman, D. C.-J. Bock, R. Bolton, D. Brodrick, M. Brothers, A. J. Brown, J. D. Bunton, W. Cheng, T. Cornwell, D. DeBoer, I. Feain, R. Gough, N. Gupta, J. C. Guzman, G. A. Hampson, S. Hay, D. B. Hayman, S. Hoyle, B. Humphreys, C. Jacka, C. A. Jackson, S. Jackson, K. Jeganathan, J. Joseph, B. S. Koribalski, M. Leach, E. S. Lensson, A. MacLeod, S. Mackay, M. Marquarding, N. M. McClure-Griffiths, P. Mirtschin, D. Mitchell, S. Neuhold, A. Ng, R. Norris, S. Pearce, R. Y. Qiao, A. E. T. Schinckel, M. Shields, T. W. Shimwell, M. Storey, E. Troup, B. Turner, J. Tuthill, A. Tzioumis, R. M. Wark, T. Westmeier, C. Wilson, T. Wilson
-
- Journal:
- Publications of the Astronomical Society of Australia / Volume 33 / 2016
- Published online by Cambridge University Press:
- 09 September 2016, e042
-
- Article
-
- You have access Access
- HTML
- Export citation
-
We describe the performance of the Boolardy Engineering Test Array, the prototype for the Australian Square Kilometre Array Pathfinder telescope. Boolardy Engineering Test Array is the first aperture synthesis radio telescope to use phased array feed technology, giving it the ability to electronically form up to nine dual-polarisation beams. We report the methods developed for forming and measuring the beams, and the adaptations that have been made to the traditional calibration and imaging procedures in order to allow BETA to function as a multi-beam aperture synthesis telescope. We describe the commissioning of the instrument and present details of Boolardy Engineering Test Array’s performance: sensitivity, beam characteristics, polarimetric properties, and image quality. We summarise the astronomical science that it has produced and draw lessons from operating Boolardy Engineering Test Array that will be relevant to the commissioning and operation of the final Australian Square Kilometre Array Path telescope.
Kinetics of CSF Phenytoin in Children
- G. Koren, Z. Barzilay, E. Schachar, N. Brand, S. Danee, H. Halkin, S.M. MacLeod
-
- Journal:
- Canadian Journal of Neurological Sciences / Volume 10 / Issue 3 / August 1983
- Published online by Cambridge University Press:
- 18 September 2015, pp. 195-197
-
- Article
-
- You have access Access
- Export citation
-
The efficacy of intravenous phenytoin for the treatment of status epilepticus is related to the rapid entry of phenytoin into brain parenchyma. There is no information concerning the correlation between phenytoin serum and CSF concentrations in children, and the application of CSF data to clinical use. We report 7 children (2–11 yrs) who were treated or exposed to phenytoin in doses between 10.5–230 mg/kg. Lumbar puncture was performed 9 times in 6 of the patients. In one patient, an intraventricular catheter permitted successive assessment of CSF phenytoin concentrations. The ratio of CSF/serum phenytoin concentrations was 0.16 ± 0.08, with gradual increase over the first 8 hours as the serum phenytoin concentration decreased. There was good correlation between therapeutic outcome and CSF phenytoin levels higher than 2 mcg/ml. In one patient the coma state secondary to phenytoin intoxication was associated with high CSF concentration (6 mcg/ml).
Rett Syndrome: Investigation of Nine Patients, including PET Scan
- Henry G. Dunn, A. Jon Stoessl, Helena H. Ho, Patrick M. MacLeod, Kenneth J. Poskitt, Doris J. Doudet, Michael Schulzer, Derek Blackstock, Teresa Dobko, Ben Koop, Giovana V. de Amorim
-
- Journal:
- Canadian Journal of Neurological Sciences / Volume 29 / Issue 4 / November 2002
- Published online by Cambridge University Press:
- 02 December 2014, pp. 345-357
-
- Article
-
- You have access Access
- Export citation
-
Background:
We describe nine females with Rett Syndrome (RS), aged 14 to 26 years. All had had developmental delay before the end of their first year and had subsequently regressed to profound dementia with apraxia, ataxia, irregular respirations and often also seizures.
Methods:The Revised Gesell developmental assessment and Alpern-Boll Developmental Profile were used in modified form. Volumetric measurements of basal ganglia using MRI were compared with the findings in nine age-matched volunteer females. Positron emission scans with [18F]-6-fluorodopa and [11C]-raclopride were performed under light anesthesia with intravenous Propofol, and the findings were compared with those in healthy control girls. Bidirectional sequencing of the coding regions of the MECP2 gene was investigated in blood samples for mutational analyses.
Results:The RS females functioned at a mental age level ranging from about 4 to 15 months. The scores correlated with height, weight and head circumference. Magnetic resonance scans of basal ganglia showed a significant reduction in the size of the caudate heads and thalami in the Rett cases. Positron emission scans demonstrated that the mean uptake of fluorodopa in RS was reduced by 13.1% in caudate and by 12.5% in putamen as compared to the controls, while dopamine D2 receptor binding was increased significantly by 9.7% in caudate and 9.6% in putamen. Mutations in the coding regions of the MECP2 gene were present in all nine patients. No significant correlation between type and location of mutation and volumetric changes or isotope uptake was demonstrable.
Conclusion:Our findings suggest a mild presynaptic deficit of nigrostriatal activity in Rett syndrome.
A Comparison of the QIDS-C16, QIDS-SR16, and the MADRS in an Adult Outpatient Clinical Sample
- Ira H. Bernstein, A. John Rush, Diane Stegman, Laurie Macleod, Bradley Witte, Madhukar H. Trivedi
-
- Journal:
- CNS Spectrums / Volume 15 / Issue 7 / July 2010
- Published online by Cambridge University Press:
- 07 November 2014, pp. 458-468
-
- Article
- Export citation
-
Background: This study compared the 16-item Clinician and Self-Report versions of the Quick Inventory of Depressive Symptomatology (QIDS-C16 and QIDS-SR16) and the 10-item Montgomery-Asberg Depression Rating Scale (MADRS) in adult outpatients. The comparison was based on psychometric features and their performance in identifying those in a major depressive episode as defined by the Mini-International Neuropsychiatric Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition.
Methods: Of 278 consecutive outpatients, 181 were depressed. Classical test theory, factor analysis, and item response theory were used to evaluate the psychometric features and receiver operating characteristic (ROC) analyses.
Results: All three measures were unidimensional. All had acceptable reliability (coefficient α=.87 for MADRS10, .82 for QIDS-C16, and .80 for QIDS-SR16). Test information function was higher for the MADRS (ie, it was most sensitive to individual differences in levels of depression). The MADRS and QIDS-C16 slightly but consistently outperformed the QIDS-SR16 in differentiating between depressed versus non-depressed patients.
Conclusion: All three measures have satisfactory psychometric properties and are valid screening tools for a major depressive episode.
Associations of cannabis and cigarette use with psychotic experiences at age 18: findings from the Avon Longitudinal Study of Parents and Children
- S. H. Gage, M. Hickman, J. Heron, M. R. Munafò, G. Lewis, J. Macleod, S. Zammit
-
- Journal:
- Psychological Medicine / Volume 44 / Issue 16 / December 2014
- Published online by Cambridge University Press:
- 10 April 2014, pp. 3435-3444
-
- Article
-
- You have access Access
- Open access
- HTML
- Export citation
-
Background.
A clearer understanding of the basis for the association between cannabis use and psychotic experiences (PEs) is required. Our aim was to examine the extent to which associations between cannabis and cigarette use and PEs are due to confounding.
Method.A cohort study of 1756 adolescents with data on cannabis use, cigarette use and PEs.
Results.Cannabis use and cigarette use at age 16 were both associated, to a similar degree, with PEs at age 18 [odds ratio (OR) 1.48, 95% confidence interval (CI) 1.18–1.86 for cannabis and OR 1.61, 95% CI 1.31–1.98 for cigarettes]. Adjustment for cigarette smoking frequency (OR 1.27, 95% CI 0.91–1.76) or other illicit drug use (OR 1.25, 95% CI 0.91–1.73) substantially attenuated the relationship between cannabis and PEs. The attenuation was to a lesser degree when cannabis use was adjusted for in the cigarette PE association (OR 1.42, 95% CI 1.05–1.92). However, almost all of the participants used cannabis with tobacco, including those who classed themselves as non-cigarette smokers.
Conclusions.Teasing out the effects of cannabis from tobacco is highly complex and may not have been dealt with adequately in studies to date, including this one. Complementary methods are required to robustly examine the independent effects of cannabis, tobacco and other illicit drugs on PEs.
The Fungus Empusa aphidis Hoffman Parasitic on the Woolly Pine Needle Aphid, Schizolachnus pini-radiatae (Davidson)1
- J. H. Grobler, D. M. MacLeod, A. J. Delyzer
-
- Journal:
- The Canadian Entomologist / Volume 94 / Issue 1 / January 1962
- Published online by Cambridge University Press:
- 31 May 2012, pp. 46-49
-
- Article
- Export citation
-
During a study on the life history and ecology of the woolly pine needle aphid, Schizolachnus pini-radiatae (Davidson), in a seven-year-old pine stand in Kirkwood township, Ontario, during the summer of 1960 (Grobler, 1962), a number of dead aphids were found the first week in September. These aphids, mummified in appearance, were shown to be infected by the fungus Empusa (= Entomophthora) aphidis Hoffman.
A BIOLOGICAL STUDY OF EPINOTIA SOLANDRIANA (LEPIDOPTERA: OLETHREUTIDAE), A LEAF ROLLER ON BIRCH IN ONTARIO
- O. H. Lindquist, L. S. Macleod
-
- Journal:
- The Canadian Entomologist / Volume 99 / Issue 10 / October 1967
- Published online by Cambridge University Press:
- 31 May 2012, pp. 1110-1114
-
- Article
- Export citation
-
The life history and habits of Epinotia solandriana Linnaeus are discussed and the immature stages described. Information is given on distribution, host trees, variations in wing pattern of the adults, laboratory rearing, and parasites.
SOIL APPLICATION OF CARBOFURAN TO CONTROL SPRUCE BUDWORM, CHORISTONEURA FUMIFERANA (LEPIDOPTERA: TORTRICIDAE), IN A MANAGED WHITE SPRUCE SEED PRODUCTION AREA
- W. H. Fogal, D. A. Winston, S. M. Lopushanski, D. A. MacLeod, A. J. Willcocks
-
- Journal:
- The Canadian Entomologist / Volume 113 / Issue 10 / October 1981
- Published online by Cambridge University Press:
- 31 May 2012, pp. 949-951
-
- Article
- Export citation
-
White spruce, Picea glauca (Moench) Voss, is a major commercial tree species used in reforestation programs throughout Canada, and seed requirements cannot be met in some years because of insect damage and the periodic nature of cone crops. The spruce budworm, Choristoneura fumiferana (Clem.), feeds on buds and cones of its hosts, causing a pronounced decrease in cone production (Schooley 1978). A current outbreak in northeastern Ontario poses a serious threat to white spruce seed supply from high value, managed seed production areas. Therefore, in 1979, we began an experiment to determine whether carbofuran, a systemic insecticide, could be used to protect buds and cones when applied to soil. We chose carbofuran because it has proved successful for control of some insects in seed orchards in the southeastern United States (DeBarr 1978)
Contributors
- Edited by Richard Appleton, University of Liverpool, Peter Camfield, Dalhousie University, Nova Scotia
-
- Book:
- Childhood Epilepsy
- Published online:
- 05 August 2011
- Print publication:
- 28 July 2011, pp viii-x
-
- Chapter
- Export citation
Contributors
-
- By Rose Teteki Abbey, K. C. Abraham, David Tuesday Adamo, LeRoy H. Aden, Efrain Agosto, Victor Aguilan, Gillian T. W. Ahlgren, Charanjit Kaur AjitSingh, Dorothy B E A Akoto, Giuseppe Alberigo, Daniel E. Albrecht, Ruth Albrecht, Daniel O. Aleshire, Urs Altermatt, Anand Amaladass, Michael Amaladoss, James N. Amanze, Lesley G. Anderson, Thomas C. Anderson, Victor Anderson, Hope S. Antone, María Pilar Aquino, Paula Arai, Victorio Araya Guillén, S. Wesley Ariarajah, Ellen T. Armour, Brett Gregory Armstrong, Atsuhiro Asano, Naim Stifan Ateek, Mahmoud Ayoub, John Alembillah Azumah, Mercedes L. García Bachmann, Irena Backus, J. Wayne Baker, Mieke Bal, Lewis V. Baldwin, William Barbieri, António Barbosa da Silva, David Basinger, Bolaji Olukemi Bateye, Oswald Bayer, Daniel H. Bays, Rosalie Beck, Nancy Elizabeth Bedford, Guy-Thomas Bedouelle, Chorbishop Seely Beggiani, Wolfgang Behringer, Christopher M. Bellitto, Byard Bennett, Harold V. Bennett, Teresa Berger, Miguel A. Bernad, Henley Bernard, Alan E. Bernstein, Jon L. Berquist, Johannes Beutler, Ana María Bidegain, Matthew P. Binkewicz, Jennifer Bird, Joseph Blenkinsopp, Dmytro Bondarenko, Paulo Bonfatti, Riet en Pim Bons-Storm, Jessica A. Boon, Marcus J. Borg, Mark Bosco, Peter C. Bouteneff, François Bovon, William D. Bowman, Paul S. Boyer, David Brakke, Richard E. Brantley, Marcus Braybrooke, Ian Breward, Ênio José da Costa Brito, Jewel Spears Brooker, Johannes Brosseder, Nicholas Canfield Read Brown, Robert F. Brown, Pamela K. Brubaker, Walter Brueggemann, Bishop Colin O. Buchanan, Stanley M. Burgess, Amy Nelson Burnett, J. Patout Burns, David B. Burrell, David Buttrick, James P. Byrd, Lavinia Byrne, Gerado Caetano, Marcos Caldas, Alkiviadis Calivas, William J. Callahan, Salvatore Calomino, Euan K. Cameron, William S. Campbell, Marcelo Ayres Camurça, Daniel F. Caner, Paul E. Capetz, Carlos F. Cardoza-Orlandi, Patrick W. Carey, Barbara Carvill, Hal Cauthron, Subhadra Mitra Channa, Mark D. Chapman, James H. Charlesworth, Kenneth R. Chase, Chen Zemin, Luciano Chianeque, Philip Chia Phin Yin, Francisca H. Chimhanda, Daniel Chiquete, John T. Chirban, Soobin Choi, Robert Choquette, Mita Choudhury, Gerald Christianson, John Chryssavgis, Sejong Chun, Esther Chung-Kim, Charles M. A. Clark, Elizabeth A. Clark, Sathianathan Clarke, Fred Cloud, John B. Cobb, W. Owen Cole, John A Coleman, John J. Collins, Sylvia Collins-Mayo, Paul K. Conkin, Beth A. Conklin, Sean Connolly, Demetrios J. Constantelos, Michael A. Conway, Paula M. Cooey, Austin Cooper, Michael L. Cooper-White, Pamela Cooper-White, L. William Countryman, Sérgio Coutinho, Pamela Couture, Shannon Craigo-Snell, James L. Crenshaw, David Crowner, Humberto Horacio Cucchetti, Lawrence S. Cunningham, Elizabeth Mason Currier, Emmanuel Cutrone, Mary L. Daniel, David D. Daniels, Robert Darden, Rolf Darge, Isaiah Dau, Jeffry C. Davis, Jane Dawson, Valentin Dedji, John W. de Gruchy, Paul DeHart, Wendy J. Deichmann Edwards, Miguel A. De La Torre, George E. Demacopoulos, Thomas de Mayo, Leah DeVun, Beatriz de Vasconcellos Dias, Dennis C. Dickerson, John M. Dillon, Luis Miguel Donatello, Igor Dorfmann-Lazarev, Susanna Drake, Jonathan A. Draper, N. Dreher Martin, Otto Dreydoppel, Angelyn Dries, A. J. Droge, Francis X. D'Sa, Marilyn Dunn, Nicole Wilkinson Duran, Rifaat Ebied, Mark J. Edwards, William H. Edwards, Leonard H. Ehrlich, Nancy L. Eiesland, Martin Elbel, J. Harold Ellens, Stephen Ellingson, Marvin M. Ellison, Robert Ellsberg, Jean Bethke Elshtain, Eldon Jay Epp, Peter C. Erb, Tassilo Erhardt, Maria Erling, Noel Leo Erskine, Gillian R. Evans, Virginia Fabella, Michael A. Fahey, Edward Farley, Margaret A. Farley, Wendy Farley, Robert Fastiggi, Seena Fazel, Duncan S. Ferguson, Helwar Figueroa, Paul Corby Finney, Kyriaki Karidoyanes FitzGerald, Thomas E. FitzGerald, John R. Fitzmier, Marie Therese Flanagan, Sabina Flanagan, Claude Flipo, Ronald B. Flowers, Carole Fontaine, David Ford, Mary Ford, Stephanie A. Ford, Jim Forest, William Franke, Robert M. Franklin, Ruth Franzén, Edward H. Friedman, Samuel Frouisou, Lorelei F. Fuchs, Jojo M. Fung, Inger Furseth, Richard R. Gaillardetz, Brandon Gallaher, China Galland, Mark Galli, Ismael García, Tharscisse Gatwa, Jean-Marie Gaudeul, Luis María Gavilanes del Castillo, Pavel L. Gavrilyuk, Volney P. Gay, Metropolitan Athanasios Geevargis, Kondothra M. George, Mary Gerhart, Simon Gikandi, Maurice Gilbert, Michael J. Gillgannon, Verónica Giménez Beliveau, Terryl Givens, Beth Glazier-McDonald, Philip Gleason, Menghun Goh, Brian Golding, Bishop Hilario M. Gomez, Michelle A. Gonzalez, Donald K. Gorrell, Roy Gottfried, Tamara Grdzelidze, Joel B. Green, Niels Henrik Gregersen, Cristina Grenholm, Herbert Griffiths, Eric W. Gritsch, Erich S. Gruen, Christoffer H. Grundmann, Paul H. Gundani, Jon P. Gunnemann, Petre Guran, Vidar L. Haanes, Jeremiah M. Hackett, Getatchew Haile, Douglas John Hall, Nicholas Hammond, Daphne Hampson, Jehu J. Hanciles, Barry Hankins, Jennifer Haraguchi, Stanley S. Harakas, Anthony John Harding, Conrad L. Harkins, J. William Harmless, Marjory Harper, Amir Harrak, Joel F. Harrington, Mark W. Harris, Susan Ashbrook Harvey, Van A. Harvey, R. Chris Hassel, Jione Havea, Daniel Hawk, Diana L. Hayes, Leslie Hayes, Priscilla Hayner, S. Mark Heim, Simo Heininen, Richard P. Heitzenrater, Eila Helander, David Hempton, Scott H. Hendrix, Jan-Olav Henriksen, Gina Hens-Piazza, Carter Heyward, Nicholas J. Higham, David Hilliard, Norman A. Hjelm, Peter C. Hodgson, Arthur Holder, M. Jan Holton, Dwight N. Hopkins, Ronnie Po-chia Hsia, Po-Ho Huang, James Hudnut-Beumler, Jennifer S. Hughes, Leonard M. Hummel, Mary E. Hunt, Laennec Hurbon, Mark Hutchinson, Susan E. Hylen, Mary Beth Ingham, H. Larry Ingle, Dale T. Irvin, Jon Isaak, Paul John Isaak, Ada María Isasi-Díaz, Hans Raun Iversen, Margaret C. Jacob, Arthur James, Maria Jansdotter-Samuelsson, David Jasper, Werner G. Jeanrond, Renée Jeffery, David Lyle Jeffrey, Theodore W. Jennings, David H. Jensen, Robin Margaret Jensen, David Jobling, Dale A. Johnson, Elizabeth A. Johnson, Maxwell E. Johnson, Sarah Johnson, Mark D. Johnston, F. Stanley Jones, James William Jones, John R. Jones, Alissa Jones Nelson, Inge Jonsson, Jan Joosten, Elizabeth Judd, Mulambya Peggy Kabonde, Robert Kaggwa, Sylvester Kahakwa, Isaac Kalimi, Ogbu U. Kalu, Eunice Kamaara, Wayne C. Kannaday, Musimbi Kanyoro, Veli-Matti Kärkkäinen, Frank Kaufmann, Léon Nguapitshi Kayongo, Richard Kearney, Alice A. Keefe, Ralph Keen, Catherine Keller, Anthony J. Kelly, Karen Kennelly, Kathi Lynn Kern, Fergus Kerr, Edward Kessler, George Kilcourse, Heup Young Kim, Kim Sung-Hae, Kim Yong-Bock, Kim Yung Suk, Richard King, Thomas M. King, Robert M. Kingdon, Ross Kinsler, Hans G. Kippenberg, Cheryl A. Kirk-Duggan, Clifton Kirkpatrick, Leonid Kishkovsky, Nadieszda Kizenko, Jeffrey Klaiber, Hans-Josef Klauck, Sidney Knight, Samuel Kobia, Robert Kolb, Karla Ann Koll, Heikki Kotila, Donald Kraybill, Philip D. W. Krey, Yves Krumenacker, Jeffrey Kah-Jin Kuan, Simanga R. Kumalo, Peter Kuzmic, Simon Shui-Man Kwan, Kwok Pui-lan, André LaCocque, Stephen E. Lahey, John Tsz Pang Lai, Emiel Lamberts, Armando Lampe, Craig Lampe, Beverly J. Lanzetta, Eve LaPlante, Lizette Larson-Miller, Ariel Bybee Laughton, Leonard Lawlor, Bentley Layton, Robin A. Leaver, Karen Lebacqz, Archie Chi Chung Lee, Marilyn J. Legge, Hervé LeGrand, D. L. LeMahieu, Raymond Lemieux, Bill J. Leonard, Ellen M. Leonard, Outi Leppä, Jean Lesaulnier, Nantawan Boonprasat Lewis, Henrietta Leyser, Alexei Lidov, Bernard Lightman, Paul Chang-Ha Lim, Carter Lindberg, Mark R. Lindsay, James R. Linville, James C. Livingston, Ann Loades, David Loades, Jean-Claude Loba-Mkole, Lo Lung Kwong, Wati Longchar, Eleazar López, David W. Lotz, Andrew Louth, Robin W. Lovin, William Luis, Frank D. Macchia, Diarmaid N. J. MacCulloch, Kirk R. MacGregor, Marjory A. MacLean, Donald MacLeod, Tomas S. Maddela, Inge Mager, Laurenti Magesa, David G. Maillu, Fortunato Mallimaci, Philip Mamalakis, Kä Mana, Ukachukwu Chris Manus, Herbert Robinson Marbury, Reuel Norman Marigza, Jacqueline Mariña, Antti Marjanen, Luiz C. L. Marques, Madipoane Masenya (ngwan'a Mphahlele), Caleb J. D. Maskell, Steve Mason, Thomas Massaro, Fernando Matamoros Ponce, András Máté-Tóth, Odair Pedroso Mateus, Dinis Matsolo, Fumitaka Matsuoka, John D'Arcy May, Yelena Mazour-Matusevich, Theodore Mbazumutima, John S. McClure, Christian McConnell, Lee Martin McDonald, Gary B. McGee, Thomas McGowan, Alister E. McGrath, Richard J. McGregor, John A. McGuckin, Maud Burnett McInerney, Elsie Anne McKee, Mary B. McKinley, James F. McMillan, Ernan McMullin, Kathleen E. McVey, M. Douglas Meeks, Monica Jyotsna Melanchthon, Ilie Melniciuc-Puica, Everett Mendoza, Raymond A. Mentzer, William W. Menzies, Ina Merdjanova, Franziska Metzger, Constant J. Mews, Marvin Meyer, Carol Meyers, Vasile Mihoc, Gunner Bjerg Mikkelsen, Maria Inêz de Castro Millen, Clyde Lee Miller, Bonnie J. Miller-McLemore, Alexander Mirkovic, Paul Misner, Nozomu Miyahira, R. W. L. Moberly, Gerald Moede, Aloo Osotsi Mojola, Sunanda Mongia, Rebeca Montemayor, James Moore, Roger E. Moore, Craig E. Morrison O.Carm, Jeffry H. Morrison, Keith Morrison, Wilson J. Moses, Tefetso Henry Mothibe, Mokgethi Motlhabi, Fulata Moyo, Henry Mugabe, Jesse Ndwiga Kanyua Mugambi, Peggy Mulambya-Kabonde, Robert Bruce Mullin, Pamela Mullins Reaves, Saskia Murk Jansen, Heleen L. Murre-Van den Berg, Augustine Musopole, Isaac M. T. Mwase, Philomena Mwaura, Cecilia Nahnfeldt, Anne Nasimiyu Wasike, Carmiña Navia Velasco, Thulani Ndlazi, Alexander Negrov, James B. Nelson, David G. Newcombe, Carol Newsom, Helen J. Nicholson, George W. E. Nickelsburg, Tatyana Nikolskaya, Damayanthi M. A. Niles, Bertil Nilsson, Nyambura Njoroge, Fidelis Nkomazana, Mary Beth Norton, Christian Nottmeier, Sonene Nyawo, Anthère Nzabatsinda, Edward T. Oakes, Gerald O'Collins, Daniel O'Connell, David W. Odell-Scott, Mercy Amba Oduyoye, Kathleen O'Grady, Oyeronke Olajubu, Thomas O'Loughlin, Dennis T. Olson, J. Steven O'Malley, Cephas N. Omenyo, Muriel Orevillo-Montenegro, César Augusto Ornellas Ramos, Agbonkhianmeghe E. Orobator, Kenan B. Osborne, Carolyn Osiek, Javier Otaola Montagne, Douglas F. Ottati, Anna May Say Pa, Irina Paert, Jerry G. Pankhurst, Aristotle Papanikolaou, Samuele F. Pardini, Stefano Parenti, Peter Paris, Sung Bae Park, Cristián G. Parker, Raquel Pastor, Joseph Pathrapankal, Daniel Patte, W. Brown Patterson, Clive Pearson, Keith F. Pecklers, Nancy Cardoso Pereira, David Horace Perkins, Pheme Perkins, Edward N. Peters, Rebecca Todd Peters, Bishop Yeznik Petrossian, Raymond Pfister, Peter C. Phan, Isabel Apawo Phiri, William S. F. Pickering, Derrick G. Pitard, William Elvis Plata, Zlatko Plese, John Plummer, James Newton Poling, Ronald Popivchak, Andrew Porter, Ute Possekel, James M. Powell, Enos Das Pradhan, Devadasan Premnath, Jaime Adrían Prieto Valladares, Anne Primavesi, Randall Prior, María Alicia Puente Lutteroth, Eduardo Guzmão Quadros, Albert Rabil, Laurent William Ramambason, Apolonio M. Ranche, Vololona Randriamanantena Andriamitandrina, Lawrence R. Rast, Paul L. Redditt, Adele Reinhartz, Rolf Rendtorff, Pål Repstad, James N. Rhodes, John K. Riches, Joerg Rieger, Sharon H. Ringe, Sandra Rios, Tyler Roberts, David M. Robinson, James M. Robinson, Joanne Maguire Robinson, Richard A. H. Robinson, Roy R. Robson, Jack B. Rogers, Maria Roginska, Sidney Rooy, Rev. Garnett Roper, Maria José Fontelas Rosado-Nunes, Andrew C. Ross, Stefan Rossbach, François Rossier, John D. Roth, John K. Roth, Phillip Rothwell, Richard E. Rubenstein, Rosemary Radford Ruether, Markku Ruotsila, John E. Rybolt, Risto Saarinen, John Saillant, Juan Sanchez, Wagner Lopes Sanchez, Hugo N. Santos, Gerhard Sauter, Gloria L. Schaab, Sandra M. Schneiders, Quentin J. Schultze, Fernando F. Segovia, Turid Karlsen Seim, Carsten Selch Jensen, Alan P. F. Sell, Frank C. Senn, Kent Davis Sensenig, Damían Setton, Bal Krishna Sharma, Carolyn J. Sharp, Thomas Sheehan, N. Gerald Shenk, Christian Sheppard, Charles Sherlock, Tabona Shoko, Walter B. Shurden, Marguerite Shuster, B. Mark Sietsema, Batara Sihombing, Neil Silberman, Clodomiro Siller, Samuel Silva-Gotay, Heikki Silvet, John K. Simmons, Hagith Sivan, James C. Skedros, Abraham Smith, Ashley A. Smith, Ted A. Smith, Daud Soesilo, Pia Søltoft, Choan-Seng (C. S.) Song, Kathryn Spink, Bryan Spinks, Eric O. Springsted, Nicolas Standaert, Brian Stanley, Glen H. Stassen, Karel Steenbrink, Stephen J. Stein, Andrea Sterk, Gregory E. Sterling, Columba Stewart, Jacques Stewart, Robert B. Stewart, Cynthia Stokes Brown, Ken Stone, Anne Stott, Elizabeth Stuart, Monya Stubbs, Marjorie Hewitt Suchocki, David Kwang-sun Suh, Scott W. Sunquist, Keith Suter, Douglas Sweeney, Charles H. Talbert, Shawqi N. Talia, Elsa Tamez, Joseph B. Tamney, Jonathan Y. Tan, Yak-Hwee Tan, Kathryn Tanner, Feiya Tao, Elizabeth S. Tapia, Aquiline Tarimo, Claire Taylor, Mark Lewis Taylor, Bishop Abba Samuel Wolde Tekestebirhan, Eugene TeSelle, M. Thomas Thangaraj, David R. Thomas, Andrew Thornley, Scott Thumma, Marcelo Timotheo da Costa, George E. “Tink” Tinker, Ola Tjørhom, Karen Jo Torjesen, Iain R. Torrance, Fernando Torres-Londoño, Archbishop Demetrios [Trakatellis], Marit Trelstad, Christine Trevett, Phyllis Trible, Johannes Tromp, Paul Turner, Robert G. Tuttle, Archbishop Desmond Tutu, Peter Tyler, Anders Tyrberg, Justin Ukpong, Javier Ulloa, Camillus Umoh, Kristi Upson-Saia, Martina Urban, Monica Uribe, Elochukwu Eugene Uzukwu, Richard Vaggione, Gabriel Vahanian, Paul Valliere, T. J. Van Bavel, Steven Vanderputten, Peter Van der Veer, Huub Van de Sandt, Louis Van Tongeren, Luke A. Veronis, Noel Villalba, Ramón Vinke, Tim Vivian, David Voas, Elena Volkova, Katharina von Kellenbach, Elina Vuola, Timothy Wadkins, Elaine M. Wainwright, Randi Jones Walker, Dewey D. Wallace, Jerry Walls, Michael J. Walsh, Philip Walters, Janet Walton, Jonathan L. Walton, Wang Xiaochao, Patricia A. Ward, David Harrington Watt, Herold D. Weiss, Laurence L. Welborn, Sharon D. Welch, Timothy Wengert, Traci C. West, Merold Westphal, David Wetherell, Barbara Wheeler, Carolinne White, Jean-Paul Wiest, Frans Wijsen, Terry L. Wilder, Felix Wilfred, Rebecca Wilkin, Daniel H. Williams, D. Newell Williams, Michael A. Williams, Vincent L. Wimbush, Gabriele Winkler, Anders Winroth, Lauri Emílio Wirth, James A. Wiseman, Ebba Witt-Brattström, Teofil Wojciechowski, John Wolffe, Kenman L. Wong, Wong Wai Ching, Linda Woodhead, Wendy M. Wright, Rose Wu, Keith E. Yandell, Gale A. Yee, Viktor Yelensky, Yeo Khiok-Khng, Gustav K. K. Yeung, Angela Yiu, Amos Yong, Yong Ting Jin, You Bin, Youhanna Nessim Youssef, Eliana Yunes, Robert Michael Zaller, Valarie H. Ziegler, Barbara Brown Zikmund, Joyce Ann Zimmerman, Aurora Zlotnik, Zhuo Xinping
- Edited by Daniel Patte, Vanderbilt University, Tennessee
-
- Book:
- The Cambridge Dictionary of Christianity
- Published online:
- 05 August 2012
- Print publication:
- 20 September 2010, pp xi-xliv
-
- Chapter
- Export citation
Densities and habitat preferences of Andean cloud-forest birds in pristine and degraded habitats in north-eastern Ecuador
- W. Cresswell, M. Hughes, R. Mellanby, S. Bright, P. Catry, J. Chaves, J. Freile, A. Gabela, H. Martineau, R. Macleod, F. Mcphie, N. Anderson, S. Holt, S. Barabas, C. Chapel, T. Sanchez
-
- Journal:
- Bird Conservation International / Volume 9 / Issue 2 / June 1999
- Published online by Cambridge University Press:
- 11 May 2010, pp. 129-145
-
- Article
-
- You have access Access
- Export citation
-
The montane cloud-forests of the north-central Andes and the montane grassland and transitional elfin forest of the central Andean páramo contain a high diversity of bird species including several restricted range and uncommon species. Little is known of how densities of Andean cloud-forest species are affected by habitat degradation. Bird densities within pristine and degraded habitats at the Guandera Biological Reserve, Carchi province, Ecuador were recorded over a 10-week period. Densities were calculated for 48 species; where densities could be compared, 69% of species occurred at a higher density in pristine habitats. Pristine forest had the highest species richness with 72 species and páramo contained 44 species. In total, 26% of pristine forest species were only found in pristine forest, 39% of páramo species only in páramo, 13% of farmland species only in farmland and there were no exclusively secondary scrub species; 47% of species found in pristine forest, and 50% found in páramo were found in both secondary scrub and farmland. Restricted range species recorded at Guandera included the Carunculated Caracara Phalcobenus carunculatus, Black-thighed Puffleg Eriocnemis derbyi, Chestnut-bellied Cotinga Doliornis remseni, Crescent-faced Antpitta Grallaricula lineifrons, Masked Mountain-tanager Buthraupis wetmorei and Black-backed Bush-tanager Urothraupis stolzmanni. Three further species that occurred at Guandera of relatively local occurrence were the Grey-breasted Mountain Toucan Andigena hypoglauca, Golden-breasted Puffleg Eriocnemis mosquera and Mountain Avocetbill Opisthoprora euryptera. Of these nine species at least five used degraded habitats, while three occurred only in pristine treeline habitats.
RESEARCH ARTICLE: Sustainability Education and Public Diplomacy: A Case Study of the United States Institute on the Environment
- John Cusick, Christina Monroe, Scott MacLeod, Nicholas H. Barker
-
- Journal:
- Environmental Practice / Volume 12 / Issue 1 / March 2010
- Published online by Cambridge University Press:
- 12 March 2010, pp. 8-17
- Print publication:
- March 2010
-
- Article
- Export citation
-
Funded by the United States (US) Department of State's Bureau of Educational and Cultural Affairs, the US Institute on the Environment organized by the East-West Center hosted 20 undergraduate and graduate students for a six-week program in May–June 2009. Through involvement in the institute, participants gained an understanding of the environmental movement in the US by engaging advocacy, market, policy, cultural, and scientific approaches to environmental issues and seeing how these approaches are intertwined in the quest for developing sustainable pathways to environmental stewardship. The institute interacted with a diverse range of stakeholders, from government policy and management representatives, activists, educators, and for-profits involved in the broadly defined environmental movement. The curriculum was designed to maximize experiential learning through a variety of exercises and activities that demonstrated the dynamic complexity of environmental stewardship. Education for Sustainable Development provided a framework to design a program with proposed outcomes that include public diplomacy. The take-home lessons of each participant and the long-term cumulative impacts they will have in their respective fields of study and places of residence will ultimately measure the success of this public diplomacy initiative.
Environmental Practice 12:8–17 (2010)
A novel predictor of multilocus haplotype homozygosity: comparison with existing predictors
- I. M. MacLEOD, T. H. E. MEUWISSEN, B. J. HAYES, M. E. GODDARD
-
- Journal:
- Genetics Research / Volume 91 / Issue 6 / December 2009
- Published online by Cambridge University Press:
- 01 February 2010, pp. 413-426
-
- Article
-
- You have access Access
- HTML
- Export citation
-
The patterns of linkage disequilibrium (LD) between dense polymorphic markers are shaped by the ancestral population history. It is therefore possible to use multilocus predictors of LD to infer past population history and to infer sharing of identical alleles in quantitative trait locus (QTL) studies. We develop a multilocus predictor of LD for pairs of haplotypes, which we term haplotype homozygosity (HHn): the probability that any two haplotypes share a given number of n adjacent identical markers or ‘runs of homozygosity’. Our method, based on simplified coalescence theory, accounts for recombination and mutation. We compare our HHn predictions, with HHn in simulated populations and with two published predictors of HHn. Our method performs consistently better across a range of population parameters, including populations with a severe bottleneck followed by expansion, compared to two published methods. We demonstrate that we can predict the pattern of HHn observed in dense single nucleotide polymorphisms (SNPs) genotyped in a cattle population, given appropriate historical changes in population size. Our method is practical for use with very large numbers of individuals and dense genome wide polymorphic DNA data. It has potential applications in inferring ancestral population history and QTL mapping studies.
Ecological studies of ixodid ticks (Acari: Ixodidae) in Zambia. III. Seasonal activity and attachment sites on cattle, with notes on other hosts
- J. MacLeod, M. H. Colbo, M. H. Madbouly, B. Mwanaumo
-
- Journal:
- Bulletin of Entomological Research / Volume 67 / Issue 1 / March 1977
- Published online by Cambridge University Press:
- 10 July 2009, pp. 161-173
-
- Article
- Export citation
-
Abstract
The seasonal activity of the adults of 13 tick species was studied on cattle herds in the Central Province of Zambia from 1969 to 1972. The six main species, Boophilus decoloratus (Koch), Hyalomma marginatum rufipes Koch, H. truncatum Koch, Amblyomma variegatum (F.), Rhipicephalus appendiculatus Neum., and R. evertsi Neum. behaved as previously described for the Southern Province. R. compositus Neum. appeared from August, with peak numbers in September–October. R. simus Koch and R. tricuspis Dön. appeared from October, for seven months and three months respectively. R. supertritus Neum. and Ixodes cavipalpus Nutt. & Warb. had a brief activity season from November to January, and R. pravus gp. and R. sanguineus gp. were active from December to July. The distribution of ticks over the body of cattle was determined by fractionised collections, which gave reliable quantitative information for nine of the species. A limited number of collections from sheep, goats and dogs are analysed in relation to season. Collections from 127 wild animals, mainly along the escarpment and riverine bush of the Zambesi, are recorded.
Ecological studies of ixodid ticks (Acari, Ixodidae) in Zambia. I. Cattle as hosts of the larvae of Amblyomma variegatum (F.) and Rhipicephalus appendiculatus neum.
- John MacLeod, M. H. Colbo
-
- Journal:
- Bulletin of Entomological Research / Volume 66 / Issue 1 / March 1976
- Published online by Cambridge University Press:
- 10 July 2009, pp. 65-74
-
- Article
- Export citation
-
The roles of cattle and alternative hosts in maintaining the immature stages of Amblyomma variegatum (F.) and Rhipicephalus appendiculatus Neum. are unknown. Weekly collections of ticks from cattle in two herds in Zambia indicated an apparently higher nymph-adult ratio in the annual totals for A. variegatum than for R. appendiculatus. The larva-nymph ratios for these herds were estimated by a patch-sampling method in which all larvae and nymphs on 100 cm2 areas on the cheek, neck, dewlap, shoulder, ribs, abdomen and lower-foreleg were collected. The overall annual ratios of larvae to nymphs on the two herds were: A. variegatum 5:1 and 14:1, R. appendiculatus 1·5:1 in both herds. The ratios suggest that cattle themselves feed larvae of A. variegatum in sufficient numbers to maintain their nymphal infestation level. The numbers of cattle-fed larvae of R. appendiculatus may not be adequate for this, and alternative hosts may play an important part in maintaining the population at existing levels. There was negligible evidence of significant shift of distribution of the immature stages over the body with advancing season, and it is suggested that patch-sampling affords a method of quantitative comparison of the relative infestations by the immature stages of ticks.
Ecological studies of ixodid ticks (Acari, Ixodidae) in Zambia. II. Ticks found on small mammals and birds
- M. H. Colbo, J. MacLeod
-
- Journal:
- Bulletin of Entomological Research / Volume 66 / Issue 3 / September 1976
- Published online by Cambridge University Press:
- 10 July 2009, pp. 489-500
-
- Article
- Export citation
-
Ticks were collected from 2136 small mammals, comprising 5 bats (5 species), 14 elephant shrews (3 species), 84 Crocidura shrews (5 species), 25 hares (1 species), 10 small carnivores (3 species), 3 hyraxes (1 species) 1998 rodents (33 species), and from 41 birds (19 species) at various localities in Zambia. From these hosts 6568 ticks (4384 larvae, 1686 nymphs, 317 males and 181 females) were recovered. Twenty-three species were positively identified and nineteen other species were assigned to genus or species-group. Host and tick records are tabulated by regions collected and for each of the two regions with the largest collections, the records are tabulated by months. The ticks collected in the high montane area near the Malawi border differed significantly from collections in other areas studied, reflecting host and climate differences. In the two areas tabulated by month, most of the immature ticks were recovered in the cool dry winter months (April to August).
High Frequency of Multidrug-Resistant Gram-Negative Rods in 2 Neonatal Intensive Care Units in the Philippines
- Jennifer M. Litzow, Christopher J. Gill, Jose B. V. Mantaring, Matthew P. Fox, William B. MacLeod, Myrna Mendoza, Sookee Mendoza, Rebecca Scobie, Charles W. Huskins, Donald A. Goldman, David H. Hamer
-
- Journal:
- Infection Control & Hospital Epidemiology / Volume 30 / Issue 6 / June 2009
- Published online by Cambridge University Press:
- 02 January 2015, pp. 543-549
- Print publication:
- June 2009
-
- Article
- Export citation
-
Background.
Although hospital-acquired infections appear to be a growing threat to the survival of newborns in the developing world, the epidemiology of this problem remains poorly characterized.
Methods.During a 10-month period, we conducted prospective longitudinal surveillance for colonization and bloodstream infection caused by gram-negative rods among all infants hospitalized in the 2 largest neonatal intensive care units in Manila, the Philippines. We determined antibiotic susceptibilities and calculated adjusted odds ratios for risk factors for bacteremia by means of multivariate logistic regression.
Results.Of 1,831 neonates enrolled during a 10-month period, 1,017 (55.5%) became newly colonized and 358 (19.6%) became bacteremic with a drug-resistant gram-negative rod, most commonly Klebsiella species, Enterobacter species, Acinetobacter species, and Pseudomonas aeruginosa. Of the invasive isolates, 20% were resistant to imipenem, 41% to trimethoprim-sulfamethoxazole, 52% to amikacin, 63% to ampicillin-sulbactam, 67% to ceftazidime, and 80% to tobramycin. The factors significantly associated with an increased risk of bacteremia were mechanical ventilation and prematurity. Additionally, colonization with a drug-resistant gram-negative rod was an independent risk factor for bacteremia (odds ratio, 1.4 [95% confidence interval, 1.0-1.9]).
Conclusions.Colonization with a drug-resistant gram-negative rod was an independent risk factor for sepsis. If our data are typical, the unusually high intensity of colonization pressure and disease caused by multidrug-resistant gram-negative rods at these 2 neonatal intensive care units indicates an emerging healthcare crisis in the developing world. Improved infection control methods are therefore critically needed in developing countries.
A.L. 63, the original British army louse powder
- H. J. Craufurd-Benson, J. MacLeod
-
- Journal:
- Journal of Hygiene / Volume 44 / Issue 4 / January 1946
- Published online by Cambridge University Press:
- 15 May 2009, pp. 294-306
-
- Article
-
- You have access Access
- Export citation
-
1. The problem of louse control by powders has been shown to be twofold, namely (a) to kill the lice present on a verminous person at the time of treatment, and (b) to prevent reinfestation of a deloused person or infestation of a clean person. In these experiments no single insecticide was found that would fulfil both functions.
2. The work shows the necessity of using laboratory tests (‘cell tests’) in conjunction with insecticide tests on the parasite living under natural conditions (‘field trials’).
3. The technique and results of the cell tests and the field trials are described in detail. In the field trials naturally louse-infested persons living in verminous surroundings were treated and examined daily to observe the true insecticidal value of each preparation.
4. Naphthalene was found to be the most effective insecticide for killing body lice quickly. It failed to give any protection against reinfestation.
5. The vegetable insecticides, derris and pyrethrum, were found to be toxic to Pediculns humanus corporis, but either alone or in combination with each other they were inferior to other combinations of insecticides.
6. The combination of high-boiling tar acids and derris resulted in the combined chemicals being more toxic to lice than either alone. This proved an activation effect, and the theory of activation is discussed.
7. Activated derris, while slow in killing lice, was shown to be the best preparation which gave protection against reinfestation.
8. The preparation referred to as A.L. 63 was outstanding as the best preparation that controlled body lice and which fulfilled the original conditions stipulated for a successful louse powder for human use. The formula is:
H.B.T.A. 2 %
Derris root 14·3 % giving 1 % rotenone and a minimum of 3 % extract in the final product
Naphthalene 50·0 %
China clay 33·7 %
The nature of each chemical in this formula is defined.
9. A.L. 63, when applied to the clothing of a verminous person, killed 95% of all lice on the treated garment in 24 hr., and gave complete protection against reinfestation for an average of 5 days, and partial protection for 8 days. When applied to clean garments as a prophylactic measure, A.L. 63 gave complete protection for an average of 7…8 days, and partial protection for approximately 16 days.
10. Patients living in a verminous environment were made to wear one shirt continuously for a month without washing it. Even under these conditions they were protected from infestation by treatment of the inside of the shirt, at 8-day intervals, with A.L. 63.
11. A short history is given of the use of A.L. 63 in the British army from 1940 to 1944.
During this work we have had much help and sympathy from many people, but we would like to place on record our especial thanks to the following: Prof. P. A. Buxton, of the London School of Hygiene and Tropical Medicine, for supplying us with the original material for establishing a louse colony, and for his great interest and encouragement during the work; Dr W. E. Parry, the Divisional Police Surgeon at Spitalfields, for his kindness in describing the best areas to search for suitable patients, and his assistance in finding suitable accommodation for establishing the ‘clinic’; those numerous volunteers, within the Cooper, McDougall and Robertson organization, who offered to feed lice when the colony was being maintained at the Research Station, and suffered much discomfort while doing so.