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Contemporary Soviet Research on Latin America
- J. Gregory Oswald
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- Journal:
- Latin American Research Review / Volume 1 / Issue 2 / Spring 1966
- Published online by Cambridge University Press:
- 24 October 2022, pp. 77-96
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This essay is divided into three parts: a discussion of the pervasive role of Marxism-Leninism in Soviet Latin American studies; an examination of the contents of a collection of translated readings of USSR scholars tentatively entitled The Soviet Image of Latin America, 1945–1965: A Documentary History, and a general survey of certain basic works devoted to the principal Latin American themes prescribed by the Communist Party of the Soviet Union.
Global redistribution of income and household energy footprints: a computational thought experiment
- Y. Oswald, J.K. Steinberger, D. Ivanova, J. Millward-Hopkins
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- Journal:
- Global Sustainability / Volume 4 / 2021
- Published online by Cambridge University Press:
- 15 January 2021, e4
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Non-technical summary
Global income inequality and energy consumption inequality are related. High-income households consume more energy than low-income ones, and for different purposes. Here, we explore the global household energy consumption implications of global income redistribution. We show that global income inequality shapes not only inequalities of energy consumption but the quantity and composition of overall energy demand. Our results call for the inclusion of income distribution into energy system models, as well as into energy and climate policy.
Technical summaryDespite a rapidly growing number of studies on the relationship between inequality and energy, there is little research estimating the effect of income redistribution on energy demand. We contribute to this debate by proposing a simple but granular and data-driven model of the global income distribution and of global household energy consumption. We isolate the effect of income distribution on household energy consumption and move beyond the assumption of aggregate income–energy elasticities. First, we model expenditure as a function of income. Second, we determine budget shares of expenditure for a variety of products and services by employing product-granular income elasticities of demand. Subsequently, we apply consumption-based final energy intensities to product and services to obtain energy footprint accounts. Testing variants of the global income distribution, we find that the ‘energy costs’ of equity are small. Equitable and inequitable distributions of income, however, entail distinct structural change in energy system terms. In an equitable world, fewer people live in energy poverty and more energy is consumed for subsistence and necessities, instead of luxury and transport.
Social media summaryEquality in global income shifts household energy footprints towards subsistence, while inequality shifts them towards transport and luxury.
The MeerKAT telescope as a pulsar facility: System verification and early science results from MeerTime
- M. Bailes, A. Jameson, F. Abbate, E. D. Barr, N. D. R. Bhat, L. Bondonneau, M. Burgay, S. J. Buchner, F. Camilo, D. J. Champion, I. Cognard, P. B. Demorest, P. C. C. Freire, T. Gautam, M. Geyer, J.-M. Griessmeier, L. Guillemot, H. Hu, F. Jankowski, S. Johnston, A. Karastergiou, R. Karuppusamy, D. Kaur, M. J. Keith, M. Kramer, J. van Leeuwen, M. E. Lower, Y. Maan, M. A. McLaughlin, B. W. Meyers, S. Osłowski, L. S. Oswald, A. Parthasarathy, T. Pennucci, B. Posselt, A. Possenti, S. M. Ransom, D. J. Reardon, A. Ridolfi, C. T. G. Schollar, M. Serylak, G. Shaifullah, M. Shamohammadi, R. M. Shannon, C. Sobey, X. Song, R. Spiewak, I. H. Stairs, B. W. Stappers, W. van Straten, A. Szary, G. Theureau, V. Venkatraman Krishnan, P. Weltevrede, N. Wex, T. D. Abbott, G. B. Adams, J. P. Burger, R. R. G. Gamatham, M. Gouws, D. M. Horn, B. Hugo, A. F. Joubert, J. R. Manley, K. McAlpine, S. S. Passmoor, A. Peens-Hough, Z. R Ramudzuli, A. Rust, S. Salie, L. C. Schwardt, R. Siebrits, G. Van Tonder, V. Van Tonder, M. G. Welz
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- Journal:
- Publications of the Astronomical Society of Australia / Volume 37 / 2020
- Published online by Cambridge University Press:
- 15 July 2020, e028
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We describe system verification tests and early science results from the pulsar processor (PTUSE) developed for the newly commissioned 64-dish SARAO MeerKAT radio telescope in South Africa. MeerKAT is a high-gain (
${\sim}2.8\,\mbox{K Jy}^{-1}$ ) low-system temperature (
${\sim}18\,\mbox{K at }20\,\mbox{cm}$ ) radio array that currently operates at 580–1 670 MHz and can produce tied-array beams suitable for pulsar observations. This paper presents results from the MeerTime Large Survey Project and commissioning tests with PTUSE. Highlights include observations of the double pulsar
$\mbox{J}0737{-}3039\mbox{A}$ , pulse profiles from 34 millisecond pulsars (MSPs) from a single 2.5-h observation of the Globular cluster Terzan 5, the rotation measure of Ter5O, a 420-sigma giant pulse from the Large Magellanic Cloud pulsar PSR
$\mbox{J}0540{-}6919$ , and nulling identified in the slow pulsar PSR J0633–2015. One of the key design specifications for MeerKAT was absolute timing errors of less than 5 ns using their novel precise time system. Our timing of two bright MSPs confirm that MeerKAT delivers exceptional timing. PSR
$\mbox{J}2241{-}5236$ exhibits a jitter limit of
$<4\,\mbox{ns h}^{-1}$ whilst timing of PSR
$\mbox{J}1909{-}3744$ over almost 11 months yields an rms residual of 66 ns with only 4 min integrations. Our results confirm that the MeerKAT is an exceptional pulsar telescope. The array can be split into four separate sub-arrays to time over 1 000 pulsars per day and the future deployment of S-band (1 750–3 500 MHz) receivers will further enhance its capabilities.
LO78: Ready for launch? A survey of readiness factors among 2019 Competence By Design launch disciplines
- W. Cheung, A. Hall, T. Dalseg, A. Oswald, L. Cook, E. Van Melle, J. Frank
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- Journal:
- Canadian Journal of Emergency Medicine / Volume 22 / Issue S1 / May 2020
- Published online by Cambridge University Press:
- 13 May 2020, pp. S35-S36
- Print publication:
- May 2020
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Introduction: A critical component for successful implementation of any innovation is an organization's readiness for change. Competence by Design (CBD) is the Royal College's major change initiative to reform the training of medical specialists in Canada. The purpose of this study was to measure readiness to implement CBD among the 2019 launch disciplines. Methods: An online survey was distributed to program directors of the 2019 CBD launch disciplines one month prior to implementation. Questions were developed based on the R = MC2 framework for organizational readiness. They addressed program motivation to implement CBD, general capacity for change, and innovation-specific capacity. Questions related to motivation and general capacity were scored using a 5-point scale of agreement. Innovation-specific capacity was measured by asking participants whether they had completed 33 key pre-implementation tasks (yes/no) in preparation for CBD. Bivariate correlations were conducted to examine the relationship between motivation, general capacity and innovation specific capacity. Results: Survey response rate was 42% (n = 79). A positive correlation was found between all three domains of readiness (motivation and general capacity, r = 0.73, p < 0.01; motivation and innovation specific capacity, r = 0.52, p < 0.01; general capacity and innovation specific capacity, r = 0.47, p < 0.01). Most respondents agreed that successful launch of CBD was a priority (74%). Fewer felt that CBD was a move in the right direction (58%) and that implementation was a manageable change (53%). While most programs indicated that their leadership (94%) and faculty and residents (87%) were supportive of change, 42% did not have experience implementing large-scale innovation and 43% indicated concerns about adequate support staff. Programs had completed an average of 72% of pre-implementation tasks. No difference was found between disciplines (p = 0.11). Activities related to curriculum mapping, competence committees and programmatic assessment had been completed by >90% of programs, while <50% of programs had engaged off-service rotations. Conclusion: Measuring readiness for change aids in the identification of factors that promote or inhibit successful implementation. These results highlight several areas where programs struggle in preparation for CBD launch. Emergency medicine training programs can use this data to target additional implementation support and ongoing faculty development initiatives.
Factors associated to resistant depression
- D. Souery, P. Oswald, I. Massat, U. Bailler, J. Bollen, K. Demyttenaere, S. Kasper, Y. Lecrubier, S. Montgomery, A. Serretti, J. Zohar, J. Mendlewicz
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- Journal:
- European Psychiatry / Volume 22 / Issue S1 / March 2007
- Published online by Cambridge University Press:
- 16 April 2020, p. S69
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Background and Aims
Few studies have been conducted looking at clinical features associated to treatment resistant depression (TRD) defined as failure to at least two consecutive antidepressant trials. The objective of this study was to identify clinical and demographic factors associated to TRD in a large sample of depressed patients who failed to reach response or remission after at least two consecutive adequate treatments.
MethodsA total of 702 patients with unipolar major depression were included in the analysis. 346 patients were considered as non resistant. The remaining 356 patients were considered as resistant with a HAM-D-17 score remaining ≥ 17 after 2 consecutive adequate trials. Cox regression models were used to examine the association between individual clinical variables and TRD.
ResultsEleven variables were found to be associated with TRD. Anxiety comorbidity (p<0.001, OR=2.6), comorbid panic disorder (p<0.001, OR=2.6) and social phobia (p<0.008, OR=2.1), personality disorder (p<0.049, OR=1.7), suicidal risk (p<0.001, OR=2.2), severity (p<0.001, OR=1.7), melancholia (p<0.018, OR=1.5), a number of hospitalizations > 1 (p<0.003, OR=1.6), recurrent episodes (p<0.009, OR=1.5), early age of onset (p<0.009, OR=2.0) and non response to the first antidepressant received lifetime (p<0.019, OR=1.6).
ConclusionsOur findings provide a set of eleven relevant clinical variables associated to TRD which can be explored at the clinical level. The statistical model used in this analysis allowed for a hierarchy of these variables (based on the OR) showing that comorbid anxiety disorder is the most powerful clinical factor associated to TRD.
Comparison of settlement-era vegetation reconstructions for STEPPS and REVEALS pollen–vegetation models in the northeastern United States
- Mathias Trachsel, Andria Dawson, Christopher J. Paciorek, John W. Williams, Jason S. McLachlan, Charles V. Cogbill, David R. Foster, Simon J. Goring, Stephen T. Jackson, W. Wyatt Oswald, Bryan N. Shuman
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- Journal:
- Quaternary Research / Volume 95 / May 2020
- Published online by Cambridge University Press:
- 07 April 2020, pp. 23-42
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Reconstructions of prehistoric vegetation composition help establish natural baselines, variability, and trajectories of forest dynamics before and during the emergence of intensive anthropogenic land use. Pollen–vegetation models (PVMs) enable such reconstructions from fossil pollen assemblages using process-based representations of taxon-specific pollen production and dispersal. However, several PVMs and variants now exist, and the sensitivity of vegetation inferences to PVM selection, variant, and calibration domain is poorly understood. Here, we compare the reconstructions, parameter estimates, and structure of a Bayesian hierarchical PVM, STEPPS, both to observations and to REVEALS, a widely used PVM, for the pre–Euro-American settlement-era vegetation in the northeastern United States (NEUS). We also compare NEUS-based STEPPS parameter estimates to those for the upper midwestern United States (UMW). Both PVMs predict the observed macroscale patterns of vegetation composition in the NEUS; however, reconstructions of minor taxa are less accurate and predictions for some taxa differ between PVMs. These differences can be attributed to intermodel differences in structure and parameter estimates. Estimates of pollen productivity from STEPPS broadly agree with estimates produced for use in REVEALS, while comparison between pollen dispersal parameter estimates shows no significant relationship. STEPPS parameter estimates are similar between the UMW and NEUS, suggesting that STEPPS parameter estimates are transferable between floristically similar regions and scales.
Constraining the geothermal heat flux in Greenland at regions of radar-detected basal water
- Soroush Rezvanbehbahani, Leigh A. Stearns, C. J. van der Veen, Gordon K. A. Oswald, Ralf Greve
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- Journal:
- Journal of Glaciology / Volume 65 / Issue 254 / December 2019
- Published online by Cambridge University Press:
- 04 November 2019, pp. 1023-1034
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The spatial distribution of basal water critically impacts the evolution of ice sheets. Current estimates of basal water distribution beneath the Greenland Ice Sheet (GrIS) contain large uncertainties due to poorly constrained boundary conditions, primarily from geothermal heat flux (GHF). The existing GHF models often contradict each other and implementing them in numerical ice-sheet models cannot reproduce the measured temperatures at ice core locations. Here we utilize two datasets of radar-detected basal water in Greenland to constrain the GHF at regions with a thawed bed. Using the three-dimensional ice-sheet model SICOPOLIS, we iteratively adjust the GHF to find the minimum GHF required to reach the bed to the pressure melting point, GHFpmp, at locations of radar-detected basal water. We identify parts of the central-east, south and northwest Greenland with significantly high GHFpmp. Conversely, we find that the majority of low-elevation regions of west Greenland and parts of northeast have very low GHFpmp. We compare the estimated constraints with the available GHF models for Greenland and show that GHF models often do not honor the estimated constraints. Our results highlight the need for community effort to reconcile the discrepancies between radar data, GHF models, and ice core information.
Low prevalence of substance use in people with 22q11.2 deletion syndrome
- Claudia Vingerhoets, Mathilde J.F. van Oudenaren, Oswald J.N. Bloemen, Erik Boot, Esther D.A. van Duin, Laurens J.M. Evers, Ania M. Fiksinski, Elemi J. Breetvelt, Lisa D. Palmer, Elfi Vergaelen, Annick Vogels, Carin Meijer, Jan Booij, Genetic Risk and Outcome of Psychosis (GROUP) investigators, Liewe de Haan, Ann Swillen, Jacob A.S. Vorstman, Anne S. Bassett, Therese A.M.J. van Amelsvoort
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- Journal:
- The British Journal of Psychiatry / Volume 215 / Issue 5 / November 2019
- Published online by Cambridge University Press:
- 03 January 2019, pp. 661-667
- Print publication:
- November 2019
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Background
22q11.2 deletion syndrome (22q11DS), one of the most common recurrent copy number variant disorders, is associated with dopaminergic abnormalities and increased risk for psychotic disorders.
AimsGiven the elevated prevalence of substance use and dopaminergic abnormalities in non-deleted patients with psychosis, we investigated the prevalence of substance use in 22q11DS, compared with that in non-deleted patients with psychosis and matched healthy controls.
MethodThis cross-sectional study involved 434 patients with 22q11DS, 265 non-deleted patients with psychosis and 134 healthy controls. Psychiatric diagnosis, full-scale IQ and COMT Val158Met genotype were determined in the 22q11DS group. Substance use data were collected according to the Composite International Diagnostic Interview.
ResultsThe prevalence of total substance use (36.9%) and substance use disorders (1.2%), and weekly amounts of alcohol and nicotine use, in patients with 22q11DS was significantly lower than in non-deleted patients with psychosis or controls. Compared with patients with 22q11DS, healthy controls were 20 times more likely to use substances in general (P < 0.001); results were also significant for alcohol and nicotine use separately. Within the 22q11DS group, there was no relationship between the prevalence of substance use and psychosis or COMT genotype. Male patients with 22q11DS were more likely to use substances than female patients with 22q11DS.
ConclusionsThe results suggest that patients with 22q11DS are at decreased risk for substance use and substance use disorders despite the increased risk of psychotic disorders. Further research into neurobiological and environmental factors involved in substance use in 22q11DS is necessary to elucidate the mechanisms involved.
Declaration of interestNone.
Updated European Consensus Statement on diagnosis and treatment of adult ADHD
- J.J.S. Kooij, D. Bijlenga, L. Salerno, R. Jaeschke, I. Bitter, J. Balázs, J. Thome, G. Dom, S. Kasper, C. Nunes Filipe, S. Stes, P. Mohr, S. Leppämäki, M. Casas, J. Bobes, J.M. Mccarthy, V. Richarte, A. Kjems Philipsen, A. Pehlivanidis, A. Niemela, B. Styr, B. Semerci, B. Bolea-Alamanac, D. Edvinsson, D. Baeyens, D. Wynchank, E. Sobanski, A. Philipsen, F. McNicholas, H. Caci, I. Mihailescu, I. Manor, I. Dobrescu, T. Saito, J. Krause, J. Fayyad, J.A. Ramos-Quiroga, K. Foeken, F. Rad, M. Adamou, M. Ohlmeier, M. Fitzgerald, M. Gill, M. Lensing, N. Motavalli Mukaddes, P. Brudkiewicz, P. Gustafsson, P. Tani, P. Oswald, P.J. Carpentier, P. De Rossi, R. Delorme, S. Markovska Simoska, S. Pallanti, S. Young, S. Bejerot, T. Lehtonen, J. Kustow, U. Müller-Sedgwick, T. Hirvikoski, V. Pironti, Y. Ginsberg, Z. Félegyházy, M.P. Garcia-Portilla, P. Asherson
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- Journal:
- European Psychiatry / Volume 56 / Issue 1 / February 2019
- Published online by Cambridge University Press:
- 16 November 2018, pp. 14-34
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Background Attention-deficit/hyperactivity disorder (ADHD) is among the most common psychiatric disorders of childhood that often persists into adulthood and old age. Yet ADHD is currently underdiagnosed and undertreated in many European countries, leading to chronicity of symptoms and impairment, due to lack of, or ineffective treatment, and higher costs of illness.
Methods The European Network Adult ADHD and the Section for Neurodevelopmental Disorders Across the Lifespan (NDAL) of the European Psychiatric Association (EPA), aim to increase awareness and knowledge of adult ADHD in and outside Europe. This Updated European Consensus Statement aims to support clinicians with research evidence and clinical experience from 63 experts of European and other countries in which ADHD in adults is recognized and treated.
Results Besides reviewing the latest research on prevalence, persistence, genetics and neurobiology of ADHD, three major questions are addressed: (1) What is the clinical picture of ADHD in adults? (2) How should ADHD be properly diagnosed in adults? (3) How should adult ADHDbe effectively treated?
Conclusions ADHD often presents as a lifelong impairing condition. The stigma surrounding ADHD, mainly due to lack of knowledge, increases the suffering of patients. Education on the lifespan perspective, diagnostic assessment, and treatment of ADHD must increase for students of general and mental health, and for psychiatry professionals. Instruments for screening and diagnosis of ADHD in adults are available, as are effective evidence-based treatments for ADHD and its negative outcomes. More research is needed on gender differences, and in older adults with ADHD.
Response of Deeproot Sedge (Cyperus entrerianus) to Herbicide and Prescribed Fire in Texas Coastal Prairie
- Jonathan R. King, Andrew J. Bennett, Warren C. Conway, David J. Rosen, Brian P. Oswald
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- Journal:
- Invasive Plant Science and Management / Volume 8 / Issue 1 / March 2015
- Published online by Cambridge University Press:
- 20 January 2017, pp. 15-31
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Introduced accidentally from South America, deeproot sedge is rapidly expanding in a variety of habitats throughout the southeastern United States. Of particular concern is its rapid expansion, naturalization, and formation of monocultures in Texas coastal prairie, one of the most imperiled temperate ecoregions in North America. The objective of this research was to examine how deeproot sedge responds to prescribed fire, to the herbicide imazapic, and to treatment combinations of both. Combinations of prescribed fire and imazapic treatments and imazapic-only treatments effectively reduced deeproot sedge cover and frequency. However, plots exposed to dormant season fires (with no imazapic) had greater deeproot sedge cover after burn treatments were applied, indicating that coastal prairie management using only dormant season prescribed fire will not work toward reduction or management of this exotic invasive species. Although deeproot sedge cover was often reduced in fire–imazapic treatment combinations, it was still present in treatment plots. Moreover, desirable functional plant groups (i.e., native bunchgrasses) did not respond positively to the fire–imazapic treatments, but in some instances, woody plant coverage increased. Repeated, long-term approaches using integrated and coordinated efforts with multiple treatment options will be necessary to restore community structure to desired compositional levels. Such integrated approaches should be effective in reducing deeproot sedge frequency, cover, and extent to more manageable levels throughout its introduced geographic range.
Total Nonstructural Carbohydrate Trends in Deeproot Sedge (Cyperus entrerianus)
- Jonathan R. King, Warren C. Conway, David J. Rosen, Brian P. Oswald, Hans M. Williams
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- Journal:
- Weed Science / Volume 62 / Issue 1 / March 2014
- Published online by Cambridge University Press:
- 20 January 2017, pp. 186-192
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Native to temperate South America, deeproot sedge has naturalized throughout the southeastern United States. Often forming dense, homogenous stands, deeproot sedge has become widespread, invasive, and potentially harmful ecologically throughout the coastal prairie ecoregion of Texas. Possessing characteristics (rapid growth, generalized habitat requirements) of other weedy congeners (purple nutsedge and yellow nutsedge), its relatively recent expansion highlights the critical need to develop effective control techniques and strategies for this species throughout this endangered ecoregion. Research was performed to delineate total nonstructural carbohydrate (TNC) trends in deeproot sedge rhizomes for development of a phenologically based schedule for herbicide applications and mechanical treatments. Overall, TNC levels were greatest in May to August and lowest from October to January, regardless of study area. Apparently, deeproot sedge exerts little energy into seed production because TNC levels were continually replenished throughout the growing season. As such, foliar-herbicide application throughout the growing season should achieve total plant kill. Conversely, deeproot sedge rhizome TNC levels never fell below 30%, even during winter, which indicates that winter mechanical treatments or winter prescribed fires will not be effective because substantial rhizome reserves are present to support resprouting during the next growing season. Beyond a priori prevention, sequential herbicide applications combined with integrated, sequential, prescribed fire and herbicide treatments will be needed for long-term deeproot sedge control throughout its geographic range.
Holocene fire and vegetation dynamics in a montane forest, North Cascade Range, Washington, USA
- Susan J. Prichard, Ze'ev Gedalof, W. Wyatt Oswald, David L. Peterson
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- Journal:
- Quaternary Research / Volume 72 / Issue 1 / July 2009
- Published online by Cambridge University Press:
- 20 January 2017, pp. 57-67
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We reconstructed a 10,500-yr fire and vegetation history of a montane site in the North Cascade Range, Washington State based on lake sediment charcoal, macrofossil and pollen records. High-resolution sampling and abundant macrofossils made it possible to analyze relationships between fire and vegetation. During the early Holocene (> 10,500 to ca. 8000 cal yr BP) forests were subalpine woodlands dominated by Pinus contorta. Around 8000 cal yr BP, P. contorta sharply declined in the macrofossil record. Shade tolerant, mesic species first appeared ca. 4500 cal yr BP. Cupressus nootkatensis appeared most recently at 2000 cal yr BP. Fire frequency varies throughout the record, with significantly shorter mean fire return intervals in the early Holocene than the mid and late Holocene. Charcoal peaks are significantly correlated with an initial increase in macrofossil accumulation rates followed by a decrease, likely corresponding to tree mortality following fire. Climate appears to be a key driver in vegetation and fire regimes over millennial time scales. Fire and other disturbances altered forest vegetation at shorter time scales, and vegetation may have mediated local fire regimes. For example, dominance of P. contorta in the early Holocene forests may have been reinforced by its susceptibility to frequent, stand-replacing fire events.
Assessing capacity to consent to treatment with cholinesterase inhibitors in dementia using a specific and standardized version of the MacArthur Competence Assessment Tool (MacCAT-T)
- Tanja Mueller, Julia Haberstroh, Maren Knebel, Frank Oswald, Roman Kaspar, Christoph J. Kemper, Petra Halder-Sinn, Johannes Schroeder, Johannes Pantel
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- Journal:
- International Psychogeriatrics / Volume 29 / Issue 2 / February 2017
- Published online by Cambridge University Press:
- 09 November 2016, pp. 333-343
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Background:
The use of assessment tools has been shown to improve the inter-rater reliability of capacity assessments. However, instrument-based capacity assessments of people with dementia face challenges. In dementia research, measuring capacity with instruments like the MacArthur Competence Assessment Tool for Treatment (MacCAT-T) mostly employ hypothetical treatment vignettes that can overwhelm the abstraction capabilities of people with dementia and are thus not always suitable for this target group. The primary aim of this study was to provide a standardized real informed consent paradigm that enables the dementia-specific properties of capacity to consent to treatment in people with dementia to be identified in a real informed consent process that is both externally valid and ethically justifiable.
Methods:The sample consisted of 53 people with mild to moderate dementia and a group of 133 people without cognitive impairment. Rather than using a hypothetical treatment vignette, we used a standardized version of the MacCAT-T to assess capacity to consent to treatment with cholinesterase inhibitors in people with dementia. Inter-rater reliability, item statistics, and psychometric properties were also investigated.
Results:Intraclass correlations (ICCs) (0.951–0.990) indicated high inter-rater reliability of the standardized real informed consent paradigm. In the dementia group, performance on different items of the MacCAT-T varied. Most people with dementia were able to express a treatment choice, and were aware of the need to take a tablet. Further information on the course of the disorder and the benefits and risks of the treatment were less understood, as was comparative reasoning regarding treatment alternatives.
Conclusion:The standardized real informed consent paradigm enabled us to detect dementia-specific characteristics of patients’ capacity to consent to treatment with cholinesterase inhibitors. In order to determine suitable enhanced consent procedures for this treatment, we recommend the consideration of MacCAT-T results on an item level. People with dementia seem to understand only basic information. Our data indicate that one useful strategy to enhance capacity to consent is to reduce attention and memory demands as far as possible.
8 - Influence of plant defenses and nutrients on trophic control of ecosystems
- from Part III - Patterns and Processes
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- By Karin T. Burghardt, Yale University, Oswald J. Schmitz, Yale University
- Edited by Torrance C. Hanley, Northeastern University, Boston, Kimberly J. La Pierre, University of California, Berkeley
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- Book:
- Trophic Ecology
- Published online:
- 05 May 2015
- Print publication:
- 07 May 2015, pp 203-232
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Summary
Introduction
Ecological systems are extraordinarily complex. Thus classical approaches to resolve ecosystem functioning have simplified analyses by conceptualizing ecosystems as being organized into trophic level compartments that contain organisms with similar feeding dependencies (e.g., producers, herbivores, carnivores) (Elton, 1927; Lindeman, 1942). Two competing worldviews on the regulation of ecosystem productivity emanated from such a conceptualization of ecosystem structure. The bottom-up view posits that the productivity of each trophic level is essentially limited by the one immediately below it (Lindeman, 1942; Feeny, 1968), while the top-down view recognizes that resource levels influence production, but contends that herbivore populations are mostly limited by predators rather than producer biomass (Hairston et al., 1960). Accordingly, predators can indirectly increase the productivity of a given system by reducing the negative effects of herbivores on plant biomass, resulting in a world that is green with plant material, rather than denuded by herbivory (Paine, 1969; Oksanen et al., 1981). Bottom-up theory countered that the world is green not because of predators, but instead due to variation in plant quality as a result of anti-herbivore defenses or weather patterns (Murdoch, 1966; Ehrlich and Birch, 1967; Scriber and Feeny, 1975; White, 1978; Feeny, 1991; Polis and Strong, 1996). This variation causes much of the “green” world to be inedible to herbivores; thus herbivores are still resource-limited.
The recognition of context-dependence in the degree of top-down or bottom-up control of ecosystems has resulted in gradual changes in how ecosystem functioning is envisioned. For instance, the “exploitation ecosystems” hypothesis (EEH) addresses context-dependence by combining elements of top-down and bottom-up concepts (Oksanen et al., 1981; Oksanen and Oksanen, 2000). At low levels of soil resource availability, plants are not productive enough to support herbivore populations and are thus bottom-up controlled (see Fig. 5.3). At medium levels of soil resources, an ecosystem can support herbivore populations, which in turn control plant productivity, while carnivores enter the ecosystem and control the herbivore population at the highest resource availability, thus releasing plant productivity from herbivore control.
Defining pathogenic verocytotoxin-producing Escherichia coli (VTEC) from cases of human infection in the European Union, 2007–2010
- W. MESSENS, D. BOLTON, G. FRANKEL, E. LIEBANA, J. McLAUCHLIN, S. MORABITO, E. OSWALD, E. J. THRELFALL
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- Journal:
- Epidemiology & Infection / Volume 143 / Issue 8 / June 2015
- Published online by Cambridge University Press:
- 24 June 2014, pp. 1652-1661
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During 2007–2010, 13 545 confirmed human verocytotoxin (VT)-producing Escherichia coli (VTEC) infections were reported in the European Union, including 777 haemolytic uraemic syndrome (HUS) cases. Clinical manifestations were reported for 53% of cases, 64% of which presented with diarrhoea alone and 10% with HUS. Isolates from 85% of cases were not fully serotyped and could not be classified on the basis of the Karmali seropathotype concept. There is no single or combination of phenotypic or genetic marker(s) that fully define ‘pathogenic’ VTEC. Isolates which contain the vtx2 (verocytotoxin 2) gene in combination with the eae (intimin-encoding) gene or aaiC (secreted protein of enteroaggregative E. coli) and aggR (plasmid-encoded regulator) genes have been associated with a higher risk of more severe illness. A molecular approach targeting genes encoding VT and other virulence determinants is thus proposed to allow an assessment of the potential severity of disease that may be associated with a given VTEC isolate.
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- By Frank Andrasik, Melissa R. Andrews, Ana Inés Ansaldo, Evangelos G. Antzoulatos, Lianhua Bai, Ellen Barrett, Linamara Battistella, Nicolas Bayle, Michael S. Beattie, Peter J. Beek, Serafin Beer, Heinrich Binder, Claire Bindschaedler, Sarah Blanton, Tasia Bobish, Michael L. Boninger, Joseph F. Bonner, Chadwick B. Boulay, Vanessa S. Boyce, Anna-Katharine Brem, Jacqueline C. Bresnahan, Floor E. Buma, Mary Bartlett Bunge, John H. Byrne, Jeffrey R. Capadona, Stefano F. Cappa, Diana D. Cardenas, Leeanne M. Carey, S. Thomas Carmichael, Glauco A. P. Caurin, Pablo Celnik, Kimberly M. Christian, Stephanie Clarke, Leonardo G. Cohen, Adriana B. Conforto, Rory A. Cooper, Rosemarie Cooper, Steven C. Cramer, Armin Curt, Mark D’Esposito, Matthew B. Dalva, Gavriel David, Brandon Delia, Wenbin Deng, Volker Dietz, Bruce H. Dobkin, Marco Domeniconi, Edith Durand, Tracey Vause Earland, Georg Ebersbach, Jonathan J. Evans, James W. Fawcett, Uri Feintuch, Toby A. Ferguson, Marie T. Filbin, Diasinou Fioravante, Itzhak Fischer, Agnes Floel, Herta Flor, Karim Fouad, Richard S. J. Frackowiak, Peter H. Gorman, Thomas W. Gould, Jean-Michel Gracies, Amparo Gutierrez, Kurt Haas, C.D. Hall, Hans-Peter Hartung, Zhigang He, Jordan Hecker, Susan J. Herdman, Seth Herman, Leigh R. Hochberg, Ahmet Höke, Fay B. Horak, Jared C. Horvath, Richard L. Huganir, Friedhelm C. Hummel, Beata Jarosiewicz, Frances E. Jensen, Michael Jöbges, Larry M. Jordan, Jon H. Kaas, Andres M. Kanner, Noomi Katz, Matthew S. Kayser, Annmarie Kelleher, Gerd Kempermann, Timothy E. Kennedy, Jürg Kesselring, Fary Khan, Rachel Kizony, Jeffery D. Kocsis, Boudewijn J. Kollen, Hubertus Köller, John W. Krakauer, Hermano I. Krebs, Gert Kwakkel, Bradley Lang, Catherine E. Lang, Helmar C. Lehmann, Angelo C. Lepore, Glenn S. Le Prell, Mindy F. Levin, Joel M. Levine, David A. Low, Marilyn MacKay-Lyons, Jeffrey D. Macklis, Margaret Mak, Francine Malouin, William C. Mann, Paul D. Marasco, Christopher J. Mathias, Laura McClure, Jan Mehrholz, Lorne M. Mendell, Robert H. Miller, Carol Milligan, Beth Mineo, Simon W. Moore, Jennifer Morgan, Charbel E-H. Moussa, Martin Munz, Randolph J. Nudo, Joseph J. Pancrazio, Theresa Pape, Alvaro Pascual-Leone, Kristin M. Pearson-Fuhrhop, P. Hunter Peckham, Tamara L. Pelleshi, Catherine Verrier Piersol, Thomas Platz, Marcus Pohl, Dejan B. Popović, Andrew M. Poulos, Maulik Purohit, Hui-Xin Qi, Debbie Rand, Mahendra S. Rao, Josef P. Rauschecker, Aimee Reiss, Carol L. Richards, Keith M. Robinson, Melvyn Roerdink, John C. Rosenbek, Serge Rossignol, Edward S. Ruthazer, Arash Sahraie, Krishnankutty Sathian, Marc H. Schieber, Brian J. Schmidt, Michael E. Selzer, Mijail D. Serruya, Himanshu Sharma, Michael Shifman, Jerry Silver, Thomas Sinkjær, George M. Smith, Young-Jin Son, Tim Spencer, John D. Steeves, Oswald Steward, Sheela Stuart, Austin J. Sumner, Chin Lik Tan, Robert W. Teasell, Gareth Thomas, Aiko K. Thompson, Richard F. Thompson, Wesley J. Thompson, Erika Timar, Ceri T. Trevethan, Christopher Trimby, Gary R. Turner, Mark H. Tuszynski, Erna A. van Niekerk, Ricardo Viana, Difei Wang, Anthony B. Ward, Nick S. Ward, Stephen G. Waxman, Patrice L. Weiss, Jörg Wissel, Steven L. Wolf, Jonathan R. Wolpaw, Sharon Wood-Dauphinee, Ross D. Zafonte, Binhai Zheng, Richard D. Zorowitz
- Edited by Michael Selzer, Stephanie Clarke, Leonardo Cohen, Gert Kwakkel, Robert Miller, Case Western Reserve University, Ohio
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- Textbook of Neural Repair and Rehabilitation
- Published online:
- 05 May 2014
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- 24 April 2014, pp ix-xvi
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- By Frank Andrasik, Melissa R. Andrews, Ana Inés Ansaldo, Evangelos G. Antzoulatos, Lianhua Bai, Ellen Barrett, Linamara Battistella, Nicolas Bayle, Michael S. Beattie, Peter J. Beek, Serafin Beer, Heinrich Binder, Claire Bindschaedler, Sarah Blanton, Tasia Bobish, Michael L. Boninger, Joseph F. Bonner, Chadwick B. Boulay, Vanessa S. Boyce, Anna-Katharine Brem, Jacqueline C. Bresnahan, Floor E. Buma, Mary Bartlett Bunge, John H. Byrne, Jeffrey R. Capadona, Stefano F. Cappa, Diana D. Cardenas, Leeanne M. Carey, S. Thomas Carmichael, Glauco A. P. Caurin, Pablo Celnik, Kimberly M. Christian, Stephanie Clarke, Leonardo G. Cohen, Adriana B. Conforto, Rory A. Cooper, Rosemarie Cooper, Steven C. Cramer, Armin Curt, Mark D’Esposito, Matthew B. Dalva, Gavriel David, Brandon Delia, Wenbin Deng, Volker Dietz, Bruce H. Dobkin, Marco Domeniconi, Edith Durand, Tracey Vause Earland, Georg Ebersbach, Jonathan J. Evans, James W. Fawcett, Uri Feintuch, Toby A. Ferguson, Marie T. Filbin, Diasinou Fioravante, Itzhak Fischer, Agnes Floel, Herta Flor, Karim Fouad, Richard S. J. Frackowiak, Peter H. Gorman, Thomas W. Gould, Jean-Michel Gracies, Amparo Gutierrez, Kurt Haas, C.D. Hall, Hans-Peter Hartung, Zhigang He, Jordan Hecker, Susan J. Herdman, Seth Herman, Leigh R. Hochberg, Ahmet Höke, Fay B. Horak, Jared C. Horvath, Richard L. Huganir, Friedhelm C. Hummel, Beata Jarosiewicz, Frances E. Jensen, Michael Jöbges, Larry M. Jordan, Jon H. Kaas, Andres M. Kanner, Noomi Katz, Matthew S. Kayser, Annmarie Kelleher, Gerd Kempermann, Timothy E. Kennedy, Jürg Kesselring, Fary Khan, Rachel Kizony, Jeffery D. Kocsis, Boudewijn J. Kollen, Hubertus Köller, John W. Krakauer, Hermano I. Krebs, Gert Kwakkel, Bradley Lang, Catherine E. Lang, Helmar C. Lehmann, Angelo C. Lepore, Glenn S. Le Prell, Mindy F. Levin, Joel M. Levine, David A. Low, Marilyn MacKay-Lyons, Jeffrey D. Macklis, Margaret Mak, Francine Malouin, William C. Mann, Paul D. Marasco, Christopher J. Mathias, Laura McClure, Jan Mehrholz, Lorne M. Mendell, Robert H. Miller, Carol Milligan, Beth Mineo, Simon W. Moore, Jennifer Morgan, Charbel E-H. Moussa, Martin Munz, Randolph J. Nudo, Joseph J. Pancrazio, Theresa Pape, Alvaro Pascual-Leone, Kristin M. Pearson-Fuhrhop, P. Hunter Peckham, Tamara L. Pelleshi, Catherine Verrier Piersol, Thomas Platz, Marcus Pohl, Dejan B. Popović, Andrew M. Poulos, Maulik Purohit, Hui-Xin Qi, Debbie Rand, Mahendra S. Rao, Josef P. Rauschecker, Aimee Reiss, Carol L. Richards, Keith M. Robinson, Melvyn Roerdink, John C. Rosenbek, Serge Rossignol, Edward S. Ruthazer, Arash Sahraie, Krishnankutty Sathian, Marc H. Schieber, Brian J. Schmidt, Michael E. Selzer, Mijail D. Serruya, Himanshu Sharma, Michael Shifman, Jerry Silver, Thomas Sinkjær, George M. Smith, Young-Jin Son, Tim Spencer, John D. Steeves, Oswald Steward, Sheela Stuart, Austin J. Sumner, Chin Lik Tan, Robert W. Teasell, Gareth Thomas, Aiko K. Thompson, Richard F. Thompson, Wesley J. Thompson, Erika Timar, Ceri T. Trevethan, Christopher Trimby, Gary R. Turner, Mark H. Tuszynski, Erna A. van Niekerk, Ricardo Viana, Difei Wang, Anthony B. Ward, Nick S. Ward, Stephen G. Waxman, Patrice L. Weiss, Jörg Wissel, Steven L. Wolf, Jonathan R. Wolpaw, Sharon Wood-Dauphinee, Ross D. Zafonte, Binhai Zheng, Richard D. Zorowitz
- Edited by Michael E. Selzer, Stephanie Clarke, Leonardo G. Cohen, Gert Kwakkel, Robert H. Miller, Case Western Reserve University, Ohio
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- Textbook of Neural Repair and Rehabilitation
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- 05 June 2014
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- 24 April 2014, pp ix-xvi
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Chapter Twenty-Seven - Coda
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- By Takayuki Ohgushi, Center for Ecological Research, Kyoto University, Oswald J. Schmitz, School of Forestry and Environmental Studies, Yale University, Robert D. Holt, Department of Biology, University of Florida
- Edited by Takayuki Ohgushi, Kyoto University, Japan, Oswald Schmitz, Yale University, Connecticut, Robert D. Holt, University of Florida
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- Trait-Mediated Indirect Interactions
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- 05 February 2013
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- 06 December 2012, pp 526-529
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Summary
Community section
Phenotypic plasticity is a ubiquitous phenomenon in nature, and provides a basis for trait-mediated indirect interactions (TMIIs) among species in ecological communities. Since trait-mediated indirect effects (TMIEs) are replete across a wide range of ecosystems, it is becoming increasingly apparent that phenotypic plasticity in response to interacting species can play an important role in determining community organization and dynamics. Below we highlight the major findings of community consequences of TMIIs in this volume.
TMIIs are common and can determine trophic structure in marine pelagic and insect host–parasitoid systems, both of which have been little explored (Chapters 3 and 4).
TMIEs in prey–predator systems should be taken into consideration in terms of non-trophic links (Chapter 2), size- and age-structure of a population (Chapter 5) and density-dependence (Chapter 6).
Herbivore-caused phenotypic plasticity and/or genetic variations of plants have significant, indirect impacts on diversity and abundance of predators, and prey–predator interactions by bottom-up cascading effects (Chapters 7 and 9).
Chapter One - Introduction
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- By Takayuki Ohgushi, Center for Ecological Research, Kyoto University, Oswald J. Schmitz, School of Forestry and Environmental Studies, Yale University, Robert D. Holt, Department of Biology, University of Florida
- Edited by Takayuki Ohgushi, Kyoto University, Japan, Oswald Schmitz, Yale University, Connecticut, Robert D. Holt, University of Florida
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- Trait-Mediated Indirect Interactions
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- 05 February 2013
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- 06 December 2012, pp 1-6
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Summary
Community ecology is experiencing a resurgence, driven in part by its central importance in addressing critical applied problems, ranging from the control of pest and invasive species, to the wise harvest of natural resources, to projecting the impact of global climate change. A fundamental tenet of community ecology is that species do not exist in isolation: they are directly, and more importantly, indirectly interconnected with myriad other species. The essential ‘glue’ that holds communities together and that makes them more than the haphazard sum of individual species is the nexus of indirect interactions among three or more species that emerges from direct interactions such as predation, competition and mutualism between pairs of species. The recognition of indirect effects has triggered a rapid growth of empirical and theoretical research that aims to predict community-level dynamics under different contexts.
Indirect effects occur when the impacts of one species on another are influenced by one or more intermediate species. Indirect effects are diverse, but can be classified broadly as either (1) density-mediated or (2) trait-mediated. Density-mediated indirect effects (DMIEs) result from numerical responses of species to each other. For instance, a fox may kill rabbits, reducing rabbit population size, and so relaxing herbivory upon herbaceous plants. Hence, the fox’s indirect effect on plants is mediated by density changes in rabbits; this is known as a trophic cascade. DMIEs, such as depicted by this trophic cascade, and other mechanisms such as apparent competition between prey mediated by the numerical response of a shared predator, have been well studied and have contributed to our understanding of community organization and ecosystem functioning in both terrestrial and aquatic systems (Holt and Lawton 1994; Polis et al. 2000; Terborgh and Estes 2010). However, the fox may not only kill rabbits, it may alter their behaviour and other traits. For instance, rabbits may hide more in the presence of foxes and so have less opportunity to feed on herbs. This indirect effect of the fox upon the plants could be strong, even though rabbit abundance remains high in the presence of foxes. In this case, it is a change in a rabbit’s trait – altered behaviour to avoid predation – that determines the outcome of the predator–prey direct interaction and the nature of the indirect effect of foxes on plants.
Chapter Seventeen - Species functional traits, trophic control and the ecosystem consequences of adaptive foraging in the middle of food chains
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- By Geoffrey C. Trussell, Marine Science Center and Department of Biology, Northeastern University, Oswald J. Schmitz, School of Forestry and Environmental Studies, Yale University
- Edited by Takayuki Ohgushi, Kyoto University, Japan, Oswald Schmitz, Yale University, Connecticut, Robert D. Holt, University of Florida
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- Trait-Mediated Indirect Interactions
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- 05 February 2013
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- 06 December 2012, pp 324-338
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Summary
Introduction
An ecosystem is often defined simply as a community of organisms interacting with each other and their biophysical environment. This definition arose from early conceptions of how the natural world is organized and is elegant in its simplicity because it captures the basic elements of a functioning system (Tansley 1935; Leopold 1939; Lindeman 1942). But those trying to develop a synthetic, empirical understanding of how ecosystems function and how they will respond to environmental change are abundantly aware that there is much inherent complexity implied by this seemingly simple definition. To cope with this complexity, ecologists have traditionally abstracted one part of the definition and elaborated the other. For example, ecosystem ecologists have long assumed that interacting organisms can be simply assigned to different compartments (e.g., producer, primary and secondary consumer, decomposer) and focused on environmental and biophysical aspects that dictate the transformation and flow of materials and energy among various compartments (Lindeman 1942; Odum 1969; Likens et al. 1970). In contrast, community ecologists have downplayed the biophysical aspects of materials and energy transfer and focused on organismal populations (Shelford 1913; Elton 1927; Hutchinson 1957; Paine 1966; MacArthur 1972), their diversity and the myriad interactions (e.g., predation, competition, facilitation) that determine their distribution and abundance (Reiners 1986; DeAngelis 1992).
Modern efforts to integrate organismal and abiotic factors into the study of ecosystems arguably were inspired by Hairston, Slobodkin and Smith’s (HSS) classic paper (Hairston et al. 1960), which sought to merge Lindeman’s trophic dynamic perspective (Lindeman 1942) and MacArthur’s population ecology perspective (MacArthur 1958) to explain why, in the face of putatively abundant herbivores, the world is still largely green rather than denuded by herbivory. HSS made the simple argument that the world is green because predators limit the impact of herbivores on plants. This paper highlighted the ecological significance of indirect effects by viewing the biological component of ecosystems as being comprised of linear food chains where interacting species (who eats whom) determine the flow of materials and energy through the ecosystem (Paine 1988; Cohen et al. 1990).
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