36 results
P.031 SMILES: Sunnybrook-St. Michael’s Integrated Leadership/QI in Endovascular Stroke care – enhancing hyperacute stroke protocols for optimized door-to-intervention times
- L Notario, AM Liu, H Chin, M Im, S Zhuo, A Lumban, R Simec, J Abalos, K Montgomery, T Fertuck, J Lee, C Convery, K Lazo, L McMillan, CM Hawkes, H Khosravani
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- Journal:
- Canadian Journal of Neurological Sciences / Volume 51 / Issue s1 / June 2024
- Published online by Cambridge University Press:
- 24 May 2024, p. S23
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Background: Hyperacute stroke care demands rapid, coordinated care. Traditional metrics like Door-to-Needle time are pivotal but insufficient for capturing the complexity of endovascular stroke interventions. The SMILES collaboration aims to standardize and optimize protocols for door-to-intervention times, incorporating Crew Resource Management (CRM). Methods: The multidisciplinary initiative integrates both hospitals, ED, neurology, and QI teams. We employed a comprehensive approach: stakeholder engagement, simulation-based learning, process mapping, and literature review. Emphasis was placed on enhancing situational awareness, triage and prioritization, cognitive load management, role clarity, effective communication, and debriefing. Results: The collaboration led to PDSA cycles and development of refined stroke protocols. Interventions included: 1) A ’zero point survey’ for team pre-arrival briefings, enhancing situational awareness and role clarity; 2) Streamlined patient registration to reduce cognitive load and improve triage efficiency; 3) Direct transfer of patients to imaging. Additionally, digital tools were implemented to facilitate communication. Simulation sessions reinforced CRM principles, leading to improved team cohesion and operational performance. Conclusions: The SMILES initiative is grounded in CRM principles by standardizing protocols and emphasizing non-technical skills crucial for high-stakes environments. This improves outcomes but also fosters a culture of safety and efficiency. Future directions include an evaluation of these protocols’ impact on patient factors.
The oxygen uptake efficiency slope in adults with CHD: group validity
- J. M. Redfern, S. Hawkes, A. Bryan, D. Cullington, R. Ashrafi
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- Cardiology in the Young , First View
- Published online by Cambridge University Press:
- 15 January 2024, pp. 1-10
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The maximal oxygen uptake (V02 max) is a well-validated measure of cardiorespiratory function that is calculated during a maximal cardiopulmonary exercise test. V02 max enables physicians to objectively assess cardiopulmonary function to aid in decision-making for patients with CHD. A significant proportion of these patients however are unable to achieve a maximal exercise test, and as such, there is a need for reliable submaximal predictors of cardiorespiratory reserve.
The oxygen uptake efficiency slope represents a measure of how effectively oxygen is extracted from the lungs and taken into the body and can be calculated from a submaximal exercise test. Its reliability as a predictor of cardiorespiratory reserve has been validated in various patient populations, but there is limited evidence for its validity in adult patients with CHD.
Retrospective analysis of cardiopulmonary exercise test data in 238 consecutive patients with CHD who completed a maximal cardiopulmonary exercise test at our tertiary cardiology centre demonstrated a strong correlation between peak V02 and the oxygen uptake efficiency slope (0.936). A strong correlation with peak V02 was also demonstrated when oxygen uptake efficiency slope was calculated at ventilatory anaerobic threshold (OUESVAT), 75% (OUES75), and 90% (OUES90) of the test (0.833, 0.905, 0.927 respectively).
In adult patients with CHD who are unable to complete a maximal cardiopulmonary exercise test, the oxygen uptake efficiency slope is a reliable indicator of cardiopulmonary fitness which correlates strongly with peak V02 at or beyond the ventilatory anaerobic threshold. Further research is required to validate the findings in patients with less common anatomies and to assess the relationship between the oxygen uptake efficiency slope and mortality.
Understanding of turbulence modulation and particle response in a particle-laden jet from direct numerical simulations
- Hua Zhou, Evatt R. Hawkes, Timothy C.W. Lau, Rey Chin, Graham J. Nathan, Haiou Wang
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- Journal of Fluid Mechanics / Volume 950 / 10 November 2022
- Published online by Cambridge University Press:
- 13 October 2022, A3
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Point-particle direct numerical simulations have been employed to quantify the turbulence modulation and particle responses in a turbulent particle-laden jet in the two-way coupled regime with an inlet Reynolds number based on bulk velocity and jet diameter $({D_j})$ of ~10 000. The investigation focuses on three cases with inlet bulk Stokes numbers of 0.3, 1.4 and 11.2. Special care is taken to account for the particle–gas slip velocity and non-uniform particle concentrations at the nozzle outlet, enabling a reasonable prediction of particle velocity and concentration fields. Turbulence modulation is quantified by the variation of the gas-phase turbulent kinetic energy (TKE). The presence of the particle phase is found to damp the gas-phase TKE in the near-field region within $5{D_j}$ from the inlet but subsequently increases the TKE in the intermediate region of (5–20)Dj. An analysis of the gas-phase TKE transport equation reveals that the direct impact of the particle phase is to dissipate TKE via the particle-induced source term. However, the finite inertia of the particle phase affects the gas-phase velocity gradients, which indirectly affects the TKE production and dissipation, leading to the observed TKE attenuation and enhancement. Particle response to the gas-phase flow is quantified. Particles are found to exhibit notably stronger response to the gas-phase axial velocity than to the radial velocity. A new dimensionless figure is presented that collapses both the axial and radial components of the particle response as a function of the local Stokes number based on their respective integral length scales.
Social motivation in infancy is associated with familial recurrence of ASD
- Natasha Marrus, Kelly N. Botteron, Zoë Hawks, John R. Pruett, Jr., Jed T. Elison, Joshua J. Jackson, Lori Markson, Adam T. Eggebrecht, Catherine A. Burrows, Lonnie Zwaigenbaum, Stephen R. Dager, Annette M. Estes, Heather Cody Hazlett, Robert T. Schultz, Joseph Piven, John N. Constantino
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- Development and Psychopathology / Volume 36 / Issue 1 / February 2024
- Published online by Cambridge University Press:
- 03 October 2022, pp. 101-111
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Pre-diagnostic deficits in social motivation are hypothesized to contribute to autism spectrum disorder (ASD), a heritable neurodevelopmental condition. We evaluated psychometric properties of a social motivation index (SMI) using parent-report item-level data from 597 participants in a prospective cohort of infant siblings at high and low familial risk for ASD. We tested whether lower SMI scores at 6, 12, and 24 months were associated with a 24-month ASD diagnosis and whether social motivation’s course differed relative to familial ASD liability. The SMI displayed good internal consistency and temporal stability. Children diagnosed with ASD displayed lower mean SMI T-scores at all ages and a decrease in mean T-scores across age. Lower group-level 6-month scores corresponded with higher familial ASD liability. Among high-risk infants, strong decline in SMI T-scores was associated with 10-fold odds of diagnosis. Infant social motivation is quantifiable by parental report, differentiates children with versus without later ASD by age 6 months, and tracks with familial ASD liability, consistent with a diagnostic and susceptibility marker of ASD. Early decrements and decline in social motivation indicate increased likelihood of ASD, highlighting social motivation’s importance to risk assessment and clarification of the ontogeny of ASD.
Testing alternative cascades from internalizing and externalizing symptoms to adolescent alcohol use and alcohol use disorder through co-occurring symptoms and peer delinquency
- Matthew D. Scalco, Craig R. Colder, Jennifer P. Read, Liliana J. Lengua, William F. Wieczorek, Larry W. Hawk, Jr.
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- Development and Psychopathology / Volume 33 / Issue 1 / February 2021
- Published online by Cambridge University Press:
- 20 April 2020, pp. 29-46
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Given the equivocal literature on the relationship between internalizing symptoms and early adolescent alcohol use (AU) and AU disorder (AUD), the present study took a developmental perspective to understand how internalizing and externalizing symptoms may operate together in the etiology of AU and AUD. We pit the delayed onset and rapid escalation hypothesis (Hussong et al., 2011) against a synthesis of the dual failure model and the stable co-occurring hypothesis (Capaldi, 1992; Colder et al., 2013, 2018) to test competing developmental pathways to adolescent AU and AUD involving problem behavior, peer delinquency, and early initiation of AU. A latent transactional and mediational framework was used to test pathways to AUD spanning developmental periods before AU initiation (Mage = 11) to early and high risk for AUD (Mage = 14–15 and Mage = 17–18). The results supported three pathways to AUD. The first started with “pure” externalizing symptoms in early childhood and involved multiple mediators, including the subsequent development of co-occurring symptoms and peer delinquency. The second pathway involved stable co-occurring symptoms. Interestingly, chronically elevated pure internalizing symptoms did not figure prominently in pathways to AUD. Selection and socialization effects between early AU and peer delinquency constituted a third pathway.
Bazirite, BaZrSi3O9, a new mineral from Rockall Island, Inverness-shire, Scotland
- B. R. Young, J. R. Hawkes, R. J. Merriman, M. T. Styles
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- Mineralogical Magazine / Volume 42 / Issue 321 / March 1978
- Published online by Cambridge University Press:
- 05 July 2018, pp. 35-40
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Bazirite, BaZrSi3O9, is one of several late-stage interstitial minerals present in the aegirine-riebeckite granite of Rockall Island. Crystals are hexagonal, probably ¯6m2, colourless, chiefly as anhedral grains. Only forms noted {10¯10} and probably {10¯14}, cleavage {0001} and probably {10¯14}. ‘Low’ and ‘high’ titanium varieties with respective mean compositions: SiO2 39·71%, ZrO2 26·38%, BaO 33·69%, TiO2 0·17%, SnO2 0·06% and SiO2 39·59%, ZrO2 26·12%, BaO 34·12%, TiO2 0·51%, SnO2 0·11%. Low and high refractive index types exist; uniaxial positive with ω = 1·6751±0·0003. ɛ = 1·6850±0·0003 and ω = 1·6813±0·0003, ɛ = 1·691 (deduced); probably due to differences in titanium content. Fluorescence (2537 Å), moderately strong, pale whitish blue. Space group almost certainly P¯6c2. Cell dimensions: low R.I. variety, a = 6·7690±0·0005 Å, c = 10·020±0·001 Å; high R.I. variety, a = 6·7662± 0·0005 Å, c = 10·158±0·0010 Å. Strongest lines are 3·80 Å (100), 2·800 (100), 5·85 (35), 3·38 (35), Z = 2. Dcalc = 3·82. Related minerals, benitoite and pabstite.
Sound generation by turbulent premixed flames
- Ali Haghiri, Mohsen Talei, Michael J. Brear, Evatt R. Hawkes
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- Journal of Fluid Mechanics / Volume 843 / 25 May 2018
- Published online by Cambridge University Press:
- 19 March 2018, pp. 29-52
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This paper presents a numerical study of the sound generated by turbulent, premixed flames. Direct numerical simulations (DNS) of two round jet flames with equivalence ratios of 0.7 and 1.0 are first carried out. Single-step chemistry is employed to reduce the computational cost, and care is taken to resolve both the near and far fields and to avoid noise reflections at the outflow boundaries. Several significant features of these two flames are noted. These include the monopolar nature of the sound from both flames, the stoichiometric flame being significantly louder than the lean flame, the observed frequency of peak acoustic spectral amplitude being consistent with prior experimental studies and the importance of so-called ‘flame annihilation’ events as acoustic sources. A simple model that relates these observed annihilation events to the far-field sound is then proposed, demonstrating a surprisingly high degree of correlation with the far-field sound from the DNS. This model is consistent with earlier works that view a premixed turbulent flame as a distribution of acoustic sources, and provides a physical explanation for the well-known monopolar content of the sound radiated by premixed turbulent flames.
Milk Thistle (Silybum marianum) Seed Germination
- J. A. Young, R. A. Evans, R. B. Hawkes
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- Journal:
- Weed Science / Volume 26 / Issue 4 / July 1978
- Published online by Cambridge University Press:
- 12 June 2017, pp. 395-398
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The germination of seeds (achenes) of milk thistle [Silybum marianum (L.) Gaertn.] was investigated. One month after harvest, milk thistle seeds had afterripening requirements related to germination temperature that limited germination to 10 to 20 C temperatures. The time required to satisfy afterripening requirements was dependent on germination temperature. Generally the higher the incubation temperature during germination, the longer the afterripening requirement (up to a maximum of 5 months). Once afterripening requirements were satisfied, milk thistle seeds germinated over a temperature range of from 0 to 30 C. Optimum germination occurred with 2 to 15 C 16-h cold periods alternating with 10 to 30 C 8-h warm periods. Emergence of milk thistle seedlings decreased with increased burial depth, but substantial emergence occurred from 8 cm. Germination on the surface of the soil or litter was greatly reduced compared to that with slight soil or litter coverage. Potassium nitrate (KNO3) added to the germination substrate at 1.0 mM enhanced the germination of milk thistle seeds at 2 and 5 C incubation temperatures.
The Mopra Southern Galactic Plane CO Survey — Data Release 1
- Catherine Braiding, M. G. Burton, R. Blackwell, C. Glück, J. Hawkes, C. Kulesa, N. Maxted, D. Rebolledo, G. Rowell, A. Stark, N. Tothill, J. S. Urquhart, F. Voisin, A. J. Walsh, P. de Wilt, G. F. Wong
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- Journal:
- Publications of the Astronomical Society of Australia / Volume 32 / 2015
- Published online by Cambridge University Press:
- 20 May 2015, e020
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We present observations of the first 10° of longitude in the Mopra CO survey of the southern Galactic plane, covering Galactic longitude l = 320–330° and latitude b = ±0.5°, and l = 327–330°, b = +0.5–1.0°. These data have been taken at 35-arcsec spatial resolution and 0.1 km s−1 spectral resolution, providing an unprecedented view of the molecular clouds and gas of the southern Galactic plane in the 109–115 GHz J = 1–0 transitions of 12CO, 13CO, C18O, and C17O. Together with information about the noise statistics from the Mopra telescope, these data can be retrieved from the Mopra CO website and the CSIRO-ATNF data archive.
On velocity and reactive scalar spectra in turbulent premixed flames
- H. Kolla, E. R. Hawkes, A. R. Kerstein, N. Swaminathan, J. H. Chen
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- Journal of Fluid Mechanics / Volume 754 / 10 September 2014
- Published online by Cambridge University Press:
- 07 August 2014, pp. 456-487
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Kinetic energy and reactive scalar spectra in turbulent premixed flames are studied from compressible three-dimensional direct numerical simulations (DNS) of a temporally evolving rectangular slot-jet premixed flame, a statistically one-dimensional configuration. The flames correspond to a lean premixed hydrogen–air mixture at an equivalence ratio of 0.7, preheated to 700 K and at 1 atm, and three DNS are considered with a fixed jet Reynolds number of 10 000 and a jet Damköhler number varying between 0.13 and 0.54. For the study of spectra, motivated by the need to account for density change, which can be locally strong in premixed flames, a new density-weighted definition for two-point velocity/scalar correlations is proposed. The density-weighted two-point correlation tensor retains the essential properties of its constant-density (incompressible) counterpart and recovers the density-weighted Reynolds stress tensor in the limit of zero separation. The density weighting also allows the derivation of balance equations for velocity and scalar spectrum functions in the wavenumber space that illuminate physics unique to combusting flows. Pressure–dilatation correlation is a source of kinetic energy at high wavenumbers and, analogously, reaction rate–scalar fluctuation correlation is a high-wavenumber source of scalar energy. These results are verified by the spectra constructed from the DNS data. The kinetic energy spectra show a distinct inertial range with a $\def \xmlpi #1{}\def \mathsfbi #1{\boldsymbol {\mathsf {#1}}}\let \le =\leqslant \let \leq =\leqslant \let \ge =\geqslant \let \geq =\geqslant \def \Pr {\mathit {Pr}}\def \Fr {\mathit {Fr}}\def \Rey {\mathit {Re}}-5/3$ scaling followed by a ‘diffusive–reactive’ range at higher wavenumbers. The exponential drop-off in this range shows a distinct inflection in the vicinity of the wavenumber corresponding to a laminar flame thickness, $\delta _L$, and this is attributed to the contribution from the pressure–dilatation term in the energy balance in wavenumber space. Likewise, a clear spike in spectra of major reactant species (hydrogen) arising from the reaction-rate term is observed at wavenumbers close to $\delta _L$. It appears that in the inertial range classical scaling laws for the spectra involving the Kolmogorov scale are applicable, but in the high-wavenumber range where chemical reactions have a strong signature the laminar flame thickness produces a better collapse. It is suggested that a full scaling should perhaps involve the Kolmogorov scale, laminar flame thickness, Damköhler number and Karlovitz number.
Early adolescent alcohol use in context: How neighborhoods, parents, and peers impact youth
- Elisa M. Trucco, Craig R. Colder, William F. Wieczorek, Liliana J. Lengua, Larry W. Hawk, Jr.
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- Development and Psychopathology / Volume 26 / Issue 2 / May 2014
- Published online by Cambridge University Press:
- 12 March 2014, pp. 425-436
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Developmental–ecological models are useful for integrating risk factors across multiple contexts and conceptualizing mediational pathways for adolescent alcohol use, yet these comprehensive models are rarely tested. This study used a developmental–ecological framework to investigate the influence of neighborhood, family, and peer contexts on alcohol use in early adolescence (N = 387). Results from a multi-informant longitudinal cross-lagged mediation path model suggested that high levels of neighborhood disadvantage were associated with high levels of alcohol use 2 years later via an indirect pathway that included exposure to delinquent peers and adolescent delinquency. Results also indicated that adolescent involvement with delinquent peers and alcohol use led to decrements in parenting, rather than being consequences of poor parenting. Overall, the study supported hypothesized relationships among key microsystems thought to influence adolescent alcohol use, and thus findings underscore the utility of developmental–ecological models of alcohol use.
Current and planned research on agriculture for improved nutrition: A mapping and a gap analysis
- J. Waage, C. Hawkes, R. Turner, E. Ferguson, D. Johnston, B. Shankar, G. McNeill, J. Hussein, H. Homans, D. Marais, F. Haseen
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- Proceedings of the Nutrition Society / Volume 72 / Issue OCE5 / 2013
- Published online by Cambridge University Press:
- 14 October 2013, E316
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The Mopra Southern Galactic Plane CO Survey
- Michael G. Burton, C. Braiding, C. Glueck, P. Goldsmith, J. Hawkes, D. J. Hollenbach, C. Kulesa, C. L. Martin, J. L. Pineda, G. Rowell, R. Simon, A. A. Stark, J. Stutzki, N. J. H. Tothill, J. S. Urquhart, C. Walker, A. J. Walsh, M. Wolfire
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- Publications of the Astronomical Society of Australia / Volume 30 / 2013
- Published online by Cambridge University Press:
- 14 August 2013, e044
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We present the first results from a new carbon monoxide (CO) survey of the southern Galactic plane being conducted with the Mopra radio telescope in Australia. The 12CO, 13CO, and C18O J = 1–0 lines are being mapped over the $l = 305^{\circ }\text{--} 345^{\circ }, b = \pm 0.5^{\circ }$ portion of the fourth quadrant of the Galaxy, at 35 arcsec spatial and 0.1 km s−1 spectral resolution. The survey is being undertaken with two principal science objectives: (i) to determine where and how molecular clouds are forming in the Galaxy and (ii) to probe the connection between molecular clouds and the ‘missing’ gas inferred from gamma-ray observations. We describe the motivation for the survey, the instrumentation and observing techniques being applied, and the data reduction and analysis methodology. In this paper, we present the data from the first degree surveyed, $l = 323^{\circ } \text{--} 324^{\circ }, b = \pm 0.5^{\circ }$. We compare the data to the previous CO survey of this region and present metrics quantifying the performance being achieved; the rms sensitivity per 0.1 km s−1 velocity channel is ~1.5 K for ${\rm ^{12}CO}$ and ~0.7 K for the other lines. We also present some results from the region surveyed, including line fluxes, column densities, molecular masses, ${\rm ^{12}CO/^{13}CO}$ line ratios, and ${\rm ^{12}CO}$ optical depths. We also examine how these quantities vary as a function of distance from the Sun when averaged over the 1 square degree survey area. Approximately 2 × 106M⊙ of molecular gas is found along the G323 sightline, with an average H2 number density of $n_{\text{H}_2} \sim 1$ cm−3 within the Solar circle. The CO data cubes will be made publicly available as they are published.
Disturbance energy transport and sound production in gaseous combustion
- Michael J. Brear, Frank Nicoud, Mohsen Talei, Alexis Giauque, Evatt R. Hawkes
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- Journal of Fluid Mechanics / Volume 707 / 25 September 2012
- Published online by Cambridge University Press:
- 12 July 2012, pp. 53-73
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This paper presents an analysis of the energy transported by disturbances in gaseous combustion. It extends the previous work of Myers (J. Fluid Mech., vol. 226, 1991, 383–400) and so includes non-zero mean-flow quantities, large-amplitude disturbances, varying specific heats and chemical non-equilibrium. This extended form of Myers’ ‘disturbance energy’ then enables complete identification of the conditions under which the famous Rayleigh source term can be derived from the equations governing combusting gas motion. These are: small disturbances in an irrotational, homentropic, non-diffusive (in terms of species, momentum and energy) and stationary mean flow at chemical equilibrium. Under these assumptions, the Rayleigh source term becomes the sole source term in a conservation equation for the classical acoustic energy. It is also argued that the exact disturbance energy flux should become an acoustic energy flux in the far-field surrounding a (reacting or non-reacting) jet. In this case, the volume integral of the disturbance energy source terms are then directly related to the area-averaged far-field sound produced by the jet. This is demonstrated by closing the disturbance energy budget over a set of aeroacoustic, direct numerical simulations of a forced, low-Mach-number, laminar, premixed flame. These budgets show that several source terms are significant, including those involving the mean-flow and entropy fields. This demonstrates that the energetics of sound generation cannot be examined by considering the Rayleigh source term alone.
Sound generation by laminar premixed flame annihilation
- MOHSEN TALEI, MICHAEL J. BREAR, EVATT R. HAWKES
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- Journal of Fluid Mechanics / Volume 679 / 25 July 2011
- Published online by Cambridge University Press:
- 18 April 2011, pp. 194-218
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This paper presents a numerical and theoretical investigation of the sound generated by premixed flame annihilation. Planar, axisymmetric and spherically symmetric flame annihilation events are considered. The compressible Navier–Stokes, energy and progress variable equations are first solved using simple chemistry simulations, resolving both the flame dynamics and the acoustics. These simulations show that the amplitude of the far-field sound produced by the annihilation events depends on the flame thickness, particularly for the axisymmetric and spherically symmetric flame annihilation events. The flame propagation velocity is also always observed to increase significantly prior to flame annihilation, which is in keeping with other reported experimental and numerical studies. A theory is then presented that relates the far-field sound to the flame annihilation event by using a previously reported and extended form of Lighthill's acoustic analogy. A comparison with the numerical results shows that this theory accurately represents the far-field sound produced by considering only the temporal heat release source term in Lighthill's acoustic analogy, as reported by others. Additional assumptions of an infinitely thin flame and constant flame speed are then invoked in an attempt to simplify the problem. In the planar annihilation, this theory results in good predictions of the overall pressure change. However, these assumptions lead to significant under-prediction of the amplitude of far-field sound produced for the axisymmetric and spherically symmetric annihilation events. Finally, dimensional reasoning supported by the simulations and theory is used to develop scalings of the far-field sound in terms of the flame parameters.
Contributors
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- By Rose Teteki Abbey, K. C. Abraham, David Tuesday Adamo, LeRoy H. Aden, Efrain Agosto, Victor Aguilan, Gillian T. W. Ahlgren, Charanjit Kaur AjitSingh, Dorothy B E A Akoto, Giuseppe Alberigo, Daniel E. Albrecht, Ruth Albrecht, Daniel O. Aleshire, Urs Altermatt, Anand Amaladass, Michael Amaladoss, James N. Amanze, Lesley G. Anderson, Thomas C. Anderson, Victor Anderson, Hope S. Antone, María Pilar Aquino, Paula Arai, Victorio Araya Guillén, S. Wesley Ariarajah, Ellen T. Armour, Brett Gregory Armstrong, Atsuhiro Asano, Naim Stifan Ateek, Mahmoud Ayoub, John Alembillah Azumah, Mercedes L. García Bachmann, Irena Backus, J. Wayne Baker, Mieke Bal, Lewis V. Baldwin, William Barbieri, António Barbosa da Silva, David Basinger, Bolaji Olukemi Bateye, Oswald Bayer, Daniel H. Bays, Rosalie Beck, Nancy Elizabeth Bedford, Guy-Thomas Bedouelle, Chorbishop Seely Beggiani, Wolfgang Behringer, Christopher M. Bellitto, Byard Bennett, Harold V. Bennett, Teresa Berger, Miguel A. Bernad, Henley Bernard, Alan E. Bernstein, Jon L. Berquist, Johannes Beutler, Ana María Bidegain, Matthew P. Binkewicz, Jennifer Bird, Joseph Blenkinsopp, Dmytro Bondarenko, Paulo Bonfatti, Riet en Pim Bons-Storm, Jessica A. Boon, Marcus J. Borg, Mark Bosco, Peter C. Bouteneff, François Bovon, William D. Bowman, Paul S. Boyer, David Brakke, Richard E. Brantley, Marcus Braybrooke, Ian Breward, Ênio José da Costa Brito, Jewel Spears Brooker, Johannes Brosseder, Nicholas Canfield Read Brown, Robert F. Brown, Pamela K. Brubaker, Walter Brueggemann, Bishop Colin O. Buchanan, Stanley M. Burgess, Amy Nelson Burnett, J. Patout Burns, David B. Burrell, David Buttrick, James P. Byrd, Lavinia Byrne, Gerado Caetano, Marcos Caldas, Alkiviadis Calivas, William J. Callahan, Salvatore Calomino, Euan K. Cameron, William S. Campbell, Marcelo Ayres Camurça, Daniel F. Caner, Paul E. Capetz, Carlos F. Cardoza-Orlandi, Patrick W. Carey, Barbara Carvill, Hal Cauthron, Subhadra Mitra Channa, Mark D. Chapman, James H. Charlesworth, Kenneth R. Chase, Chen Zemin, Luciano Chianeque, Philip Chia Phin Yin, Francisca H. Chimhanda, Daniel Chiquete, John T. Chirban, Soobin Choi, Robert Choquette, Mita Choudhury, Gerald Christianson, John Chryssavgis, Sejong Chun, Esther Chung-Kim, Charles M. A. Clark, Elizabeth A. Clark, Sathianathan Clarke, Fred Cloud, John B. Cobb, W. Owen Cole, John A Coleman, John J. Collins, Sylvia Collins-Mayo, Paul K. Conkin, Beth A. Conklin, Sean Connolly, Demetrios J. Constantelos, Michael A. Conway, Paula M. Cooey, Austin Cooper, Michael L. Cooper-White, Pamela Cooper-White, L. William Countryman, Sérgio Coutinho, Pamela Couture, Shannon Craigo-Snell, James L. Crenshaw, David Crowner, Humberto Horacio Cucchetti, Lawrence S. Cunningham, Elizabeth Mason Currier, Emmanuel Cutrone, Mary L. Daniel, David D. Daniels, Robert Darden, Rolf Darge, Isaiah Dau, Jeffry C. Davis, Jane Dawson, Valentin Dedji, John W. de Gruchy, Paul DeHart, Wendy J. Deichmann Edwards, Miguel A. De La Torre, George E. Demacopoulos, Thomas de Mayo, Leah DeVun, Beatriz de Vasconcellos Dias, Dennis C. Dickerson, John M. Dillon, Luis Miguel Donatello, Igor Dorfmann-Lazarev, Susanna Drake, Jonathan A. Draper, N. Dreher Martin, Otto Dreydoppel, Angelyn Dries, A. J. Droge, Francis X. D'Sa, Marilyn Dunn, Nicole Wilkinson Duran, Rifaat Ebied, Mark J. Edwards, William H. Edwards, Leonard H. Ehrlich, Nancy L. Eiesland, Martin Elbel, J. Harold Ellens, Stephen Ellingson, Marvin M. Ellison, Robert Ellsberg, Jean Bethke Elshtain, Eldon Jay Epp, Peter C. Erb, Tassilo Erhardt, Maria Erling, Noel Leo Erskine, Gillian R. Evans, Virginia Fabella, Michael A. Fahey, Edward Farley, Margaret A. Farley, Wendy Farley, Robert Fastiggi, Seena Fazel, Duncan S. Ferguson, Helwar Figueroa, Paul Corby Finney, Kyriaki Karidoyanes FitzGerald, Thomas E. FitzGerald, John R. Fitzmier, Marie Therese Flanagan, Sabina Flanagan, Claude Flipo, Ronald B. Flowers, Carole Fontaine, David Ford, Mary Ford, Stephanie A. Ford, Jim Forest, William Franke, Robert M. Franklin, Ruth Franzén, Edward H. Friedman, Samuel Frouisou, Lorelei F. Fuchs, Jojo M. Fung, Inger Furseth, Richard R. Gaillardetz, Brandon Gallaher, China Galland, Mark Galli, Ismael García, Tharscisse Gatwa, Jean-Marie Gaudeul, Luis María Gavilanes del Castillo, Pavel L. Gavrilyuk, Volney P. Gay, Metropolitan Athanasios Geevargis, Kondothra M. George, Mary Gerhart, Simon Gikandi, Maurice Gilbert, Michael J. Gillgannon, Verónica Giménez Beliveau, Terryl Givens, Beth Glazier-McDonald, Philip Gleason, Menghun Goh, Brian Golding, Bishop Hilario M. Gomez, Michelle A. Gonzalez, Donald K. Gorrell, Roy Gottfried, Tamara Grdzelidze, Joel B. Green, Niels Henrik Gregersen, Cristina Grenholm, Herbert Griffiths, Eric W. Gritsch, Erich S. Gruen, Christoffer H. Grundmann, Paul H. Gundani, Jon P. Gunnemann, Petre Guran, Vidar L. Haanes, Jeremiah M. Hackett, Getatchew Haile, Douglas John Hall, Nicholas Hammond, Daphne Hampson, Jehu J. Hanciles, Barry Hankins, Jennifer Haraguchi, Stanley S. Harakas, Anthony John Harding, Conrad L. Harkins, J. William Harmless, Marjory Harper, Amir Harrak, Joel F. Harrington, Mark W. Harris, Susan Ashbrook Harvey, Van A. Harvey, R. Chris Hassel, Jione Havea, Daniel Hawk, Diana L. Hayes, Leslie Hayes, Priscilla Hayner, S. Mark Heim, Simo Heininen, Richard P. Heitzenrater, Eila Helander, David Hempton, Scott H. Hendrix, Jan-Olav Henriksen, Gina Hens-Piazza, Carter Heyward, Nicholas J. Higham, David Hilliard, Norman A. Hjelm, Peter C. Hodgson, Arthur Holder, M. Jan Holton, Dwight N. Hopkins, Ronnie Po-chia Hsia, Po-Ho Huang, James Hudnut-Beumler, Jennifer S. Hughes, Leonard M. Hummel, Mary E. Hunt, Laennec Hurbon, Mark Hutchinson, Susan E. Hylen, Mary Beth Ingham, H. Larry Ingle, Dale T. Irvin, Jon Isaak, Paul John Isaak, Ada María Isasi-Díaz, Hans Raun Iversen, Margaret C. Jacob, Arthur James, Maria Jansdotter-Samuelsson, David Jasper, Werner G. Jeanrond, Renée Jeffery, David Lyle Jeffrey, Theodore W. Jennings, David H. Jensen, Robin Margaret Jensen, David Jobling, Dale A. Johnson, Elizabeth A. Johnson, Maxwell E. Johnson, Sarah Johnson, Mark D. Johnston, F. Stanley Jones, James William Jones, John R. Jones, Alissa Jones Nelson, Inge Jonsson, Jan Joosten, Elizabeth Judd, Mulambya Peggy Kabonde, Robert Kaggwa, Sylvester Kahakwa, Isaac Kalimi, Ogbu U. Kalu, Eunice Kamaara, Wayne C. Kannaday, Musimbi Kanyoro, Veli-Matti Kärkkäinen, Frank Kaufmann, Léon Nguapitshi Kayongo, Richard Kearney, Alice A. Keefe, Ralph Keen, Catherine Keller, Anthony J. Kelly, Karen Kennelly, Kathi Lynn Kern, Fergus Kerr, Edward Kessler, George Kilcourse, Heup Young Kim, Kim Sung-Hae, Kim Yong-Bock, Kim Yung Suk, Richard King, Thomas M. King, Robert M. Kingdon, Ross Kinsler, Hans G. Kippenberg, Cheryl A. Kirk-Duggan, Clifton Kirkpatrick, Leonid Kishkovsky, Nadieszda Kizenko, Jeffrey Klaiber, Hans-Josef Klauck, Sidney Knight, Samuel Kobia, Robert Kolb, Karla Ann Koll, Heikki Kotila, Donald Kraybill, Philip D. W. Krey, Yves Krumenacker, Jeffrey Kah-Jin Kuan, Simanga R. Kumalo, Peter Kuzmic, Simon Shui-Man Kwan, Kwok Pui-lan, André LaCocque, Stephen E. Lahey, John Tsz Pang Lai, Emiel Lamberts, Armando Lampe, Craig Lampe, Beverly J. Lanzetta, Eve LaPlante, Lizette Larson-Miller, Ariel Bybee Laughton, Leonard Lawlor, Bentley Layton, Robin A. Leaver, Karen Lebacqz, Archie Chi Chung Lee, Marilyn J. Legge, Hervé LeGrand, D. L. LeMahieu, Raymond Lemieux, Bill J. Leonard, Ellen M. Leonard, Outi Leppä, Jean Lesaulnier, Nantawan Boonprasat Lewis, Henrietta Leyser, Alexei Lidov, Bernard Lightman, Paul Chang-Ha Lim, Carter Lindberg, Mark R. Lindsay, James R. Linville, James C. Livingston, Ann Loades, David Loades, Jean-Claude Loba-Mkole, Lo Lung Kwong, Wati Longchar, Eleazar López, David W. Lotz, Andrew Louth, Robin W. Lovin, William Luis, Frank D. Macchia, Diarmaid N. J. MacCulloch, Kirk R. MacGregor, Marjory A. MacLean, Donald MacLeod, Tomas S. Maddela, Inge Mager, Laurenti Magesa, David G. Maillu, Fortunato Mallimaci, Philip Mamalakis, Kä Mana, Ukachukwu Chris Manus, Herbert Robinson Marbury, Reuel Norman Marigza, Jacqueline Mariña, Antti Marjanen, Luiz C. L. Marques, Madipoane Masenya (ngwan'a Mphahlele), Caleb J. D. Maskell, Steve Mason, Thomas Massaro, Fernando Matamoros Ponce, András Máté-Tóth, Odair Pedroso Mateus, Dinis Matsolo, Fumitaka Matsuoka, John D'Arcy May, Yelena Mazour-Matusevich, Theodore Mbazumutima, John S. McClure, Christian McConnell, Lee Martin McDonald, Gary B. McGee, Thomas McGowan, Alister E. McGrath, Richard J. McGregor, John A. McGuckin, Maud Burnett McInerney, Elsie Anne McKee, Mary B. McKinley, James F. McMillan, Ernan McMullin, Kathleen E. McVey, M. Douglas Meeks, Monica Jyotsna Melanchthon, Ilie Melniciuc-Puica, Everett Mendoza, Raymond A. Mentzer, William W. Menzies, Ina Merdjanova, Franziska Metzger, Constant J. Mews, Marvin Meyer, Carol Meyers, Vasile Mihoc, Gunner Bjerg Mikkelsen, Maria Inêz de Castro Millen, Clyde Lee Miller, Bonnie J. Miller-McLemore, Alexander Mirkovic, Paul Misner, Nozomu Miyahira, R. W. L. Moberly, Gerald Moede, Aloo Osotsi Mojola, Sunanda Mongia, Rebeca Montemayor, James Moore, Roger E. Moore, Craig E. Morrison O.Carm, Jeffry H. Morrison, Keith Morrison, Wilson J. Moses, Tefetso Henry Mothibe, Mokgethi Motlhabi, Fulata Moyo, Henry Mugabe, Jesse Ndwiga Kanyua Mugambi, Peggy Mulambya-Kabonde, Robert Bruce Mullin, Pamela Mullins Reaves, Saskia Murk Jansen, Heleen L. Murre-Van den Berg, Augustine Musopole, Isaac M. T. Mwase, Philomena Mwaura, Cecilia Nahnfeldt, Anne Nasimiyu Wasike, Carmiña Navia Velasco, Thulani Ndlazi, Alexander Negrov, James B. Nelson, David G. Newcombe, Carol Newsom, Helen J. Nicholson, George W. E. Nickelsburg, Tatyana Nikolskaya, Damayanthi M. A. Niles, Bertil Nilsson, Nyambura Njoroge, Fidelis Nkomazana, Mary Beth Norton, Christian Nottmeier, Sonene Nyawo, Anthère Nzabatsinda, Edward T. Oakes, Gerald O'Collins, Daniel O'Connell, David W. Odell-Scott, Mercy Amba Oduyoye, Kathleen O'Grady, Oyeronke Olajubu, Thomas O'Loughlin, Dennis T. Olson, J. Steven O'Malley, Cephas N. Omenyo, Muriel Orevillo-Montenegro, César Augusto Ornellas Ramos, Agbonkhianmeghe E. Orobator, Kenan B. Osborne, Carolyn Osiek, Javier Otaola Montagne, Douglas F. Ottati, Anna May Say Pa, Irina Paert, Jerry G. Pankhurst, Aristotle Papanikolaou, Samuele F. Pardini, Stefano Parenti, Peter Paris, Sung Bae Park, Cristián G. Parker, Raquel Pastor, Joseph Pathrapankal, Daniel Patte, W. Brown Patterson, Clive Pearson, Keith F. Pecklers, Nancy Cardoso Pereira, David Horace Perkins, Pheme Perkins, Edward N. Peters, Rebecca Todd Peters, Bishop Yeznik Petrossian, Raymond Pfister, Peter C. Phan, Isabel Apawo Phiri, William S. F. Pickering, Derrick G. Pitard, William Elvis Plata, Zlatko Plese, John Plummer, James Newton Poling, Ronald Popivchak, Andrew Porter, Ute Possekel, James M. Powell, Enos Das Pradhan, Devadasan Premnath, Jaime Adrían Prieto Valladares, Anne Primavesi, Randall Prior, María Alicia Puente Lutteroth, Eduardo Guzmão Quadros, Albert Rabil, Laurent William Ramambason, Apolonio M. Ranche, Vololona Randriamanantena Andriamitandrina, Lawrence R. Rast, Paul L. Redditt, Adele Reinhartz, Rolf Rendtorff, Pål Repstad, James N. Rhodes, John K. Riches, Joerg Rieger, Sharon H. Ringe, Sandra Rios, Tyler Roberts, David M. Robinson, James M. Robinson, Joanne Maguire Robinson, Richard A. H. Robinson, Roy R. Robson, Jack B. Rogers, Maria Roginska, Sidney Rooy, Rev. Garnett Roper, Maria José Fontelas Rosado-Nunes, Andrew C. Ross, Stefan Rossbach, François Rossier, John D. Roth, John K. Roth, Phillip Rothwell, Richard E. Rubenstein, Rosemary Radford Ruether, Markku Ruotsila, John E. Rybolt, Risto Saarinen, John Saillant, Juan Sanchez, Wagner Lopes Sanchez, Hugo N. Santos, Gerhard Sauter, Gloria L. Schaab, Sandra M. Schneiders, Quentin J. Schultze, Fernando F. Segovia, Turid Karlsen Seim, Carsten Selch Jensen, Alan P. F. Sell, Frank C. Senn, Kent Davis Sensenig, Damían Setton, Bal Krishna Sharma, Carolyn J. Sharp, Thomas Sheehan, N. Gerald Shenk, Christian Sheppard, Charles Sherlock, Tabona Shoko, Walter B. Shurden, Marguerite Shuster, B. Mark Sietsema, Batara Sihombing, Neil Silberman, Clodomiro Siller, Samuel Silva-Gotay, Heikki Silvet, John K. Simmons, Hagith Sivan, James C. Skedros, Abraham Smith, Ashley A. Smith, Ted A. Smith, Daud Soesilo, Pia Søltoft, Choan-Seng (C. S.) Song, Kathryn Spink, Bryan Spinks, Eric O. Springsted, Nicolas Standaert, Brian Stanley, Glen H. Stassen, Karel Steenbrink, Stephen J. Stein, Andrea Sterk, Gregory E. Sterling, Columba Stewart, Jacques Stewart, Robert B. Stewart, Cynthia Stokes Brown, Ken Stone, Anne Stott, Elizabeth Stuart, Monya Stubbs, Marjorie Hewitt Suchocki, David Kwang-sun Suh, Scott W. Sunquist, Keith Suter, Douglas Sweeney, Charles H. Talbert, Shawqi N. Talia, Elsa Tamez, Joseph B. Tamney, Jonathan Y. Tan, Yak-Hwee Tan, Kathryn Tanner, Feiya Tao, Elizabeth S. Tapia, Aquiline Tarimo, Claire Taylor, Mark Lewis Taylor, Bishop Abba Samuel Wolde Tekestebirhan, Eugene TeSelle, M. Thomas Thangaraj, David R. Thomas, Andrew Thornley, Scott Thumma, Marcelo Timotheo da Costa, George E. “Tink” Tinker, Ola Tjørhom, Karen Jo Torjesen, Iain R. Torrance, Fernando Torres-Londoño, Archbishop Demetrios [Trakatellis], Marit Trelstad, Christine Trevett, Phyllis Trible, Johannes Tromp, Paul Turner, Robert G. Tuttle, Archbishop Desmond Tutu, Peter Tyler, Anders Tyrberg, Justin Ukpong, Javier Ulloa, Camillus Umoh, Kristi Upson-Saia, Martina Urban, Monica Uribe, Elochukwu Eugene Uzukwu, Richard Vaggione, Gabriel Vahanian, Paul Valliere, T. J. Van Bavel, Steven Vanderputten, Peter Van der Veer, Huub Van de Sandt, Louis Van Tongeren, Luke A. Veronis, Noel Villalba, Ramón Vinke, Tim Vivian, David Voas, Elena Volkova, Katharina von Kellenbach, Elina Vuola, Timothy Wadkins, Elaine M. Wainwright, Randi Jones Walker, Dewey D. Wallace, Jerry Walls, Michael J. Walsh, Philip Walters, Janet Walton, Jonathan L. Walton, Wang Xiaochao, Patricia A. Ward, David Harrington Watt, Herold D. Weiss, Laurence L. Welborn, Sharon D. Welch, Timothy Wengert, Traci C. West, Merold Westphal, David Wetherell, Barbara Wheeler, Carolinne White, Jean-Paul Wiest, Frans Wijsen, Terry L. Wilder, Felix Wilfred, Rebecca Wilkin, Daniel H. Williams, D. Newell Williams, Michael A. Williams, Vincent L. Wimbush, Gabriele Winkler, Anders Winroth, Lauri Emílio Wirth, James A. Wiseman, Ebba Witt-Brattström, Teofil Wojciechowski, John Wolffe, Kenman L. Wong, Wong Wai Ching, Linda Woodhead, Wendy M. Wright, Rose Wu, Keith E. Yandell, Gale A. Yee, Viktor Yelensky, Yeo Khiok-Khng, Gustav K. K. Yeung, Angela Yiu, Amos Yong, Yong Ting Jin, You Bin, Youhanna Nessim Youssef, Eliana Yunes, Robert Michael Zaller, Valarie H. Ziegler, Barbara Brown Zikmund, Joyce Ann Zimmerman, Aurora Zlotnik, Zhuo Xinping
- Edited by Daniel Patte, Vanderbilt University, Tennessee
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- The Cambridge Dictionary of Christianity
- Published online:
- 05 August 2012
- Print publication:
- 20 September 2010, pp xi-xliv
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Turbulent flame–wall interaction: a direct numerical simulation study
- A. GRUBER, R. SANKARAN, E. R. HAWKES, J. H. CHEN
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- Journal of Fluid Mechanics / Volume 658 / 10 September 2010
- Published online by Cambridge University Press:
- 19 August 2010, pp. 5-32
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A turbulent flame–wall interaction (FWI) configuration is studied using three-dimensional direct numerical simulation (DNS) and detailed chemical kinetics. The simulations are used to investigate the effects of the wall turbulent boundary layer (i) on the structure of a hydrogen–air premixed flame, (ii) on its near-wall propagation characteristics and (iii) on the spatial and temporal patterns of the convective wall heat flux. Results show that the local flame thickness and propagation speed vary between the core flow and the boundary layer, resulting in a regime change from flamelet near the channel centreline to a thickened flame at the wall. This finding has strong implications for the modelling of turbulent combustion using Reynolds-averaged Navier–Stokes or large-eddy simulation techniques. Moreover, the DNS results suggest that the near-wall coherent turbulent structures play an important role on the convective wall heat transfer by pushing the hot reactive zone towards the cold solid surface. At the wall, exothermic radical recombination reactions become important, and are responsible for approximately 70% of the overall heat release rate at the wall. Spectral analysis of the convective wall heat flux provides an unambiguous picture of its spatial and temporal patterns, previously unobserved, that is directly related to the spatial and temporal characteristic scalings of the coherent near-wall turbulent structures.
Postnatal decline of maternally acquired rubella antibodies
- M. J. Cloonan, R. A. Hawkes, L. H. Stevens
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- Journal:
- Journal of Hygiene / Volume 68 / Issue 3 / September 1970
- Published online by Cambridge University Press:
- 15 May 2009, pp. 461-468
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The postnatal decline of maternally acquired rubella antibody was studied in a large group of infants. A high degree of variability was found in the rate of antibody decline (half-life). Ninety-two babies had rubella antibody half-lives lying between 14 and 70 days and three had values considerably higher. There was no significant difference between the rubella antibody half-lives of the sexes. The antibody titre at birth was weakly correlated with both birth weight and gestational age. There was a highly significant positive correlation between the baby's antibody titre at birth and that of its mother. There was a positive relationship between the half-life and the persistence of rubella antibody. Some babies had no detectable antibody by 2 months whereas others still possessed antibody at 9 months. It was found that the relationship between the half-life and the rubella antibody titre at or near birth could be described by a rectangular hyperbola.
Postnatal decline of maternally acquired viral antibodies of different specificities
- M. J. Cloonan, R. A. Hawkes, L. H. Stevens
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- Journal:
- Journal of Hygiene / Volume 69 / Issue 3 / September 1971
- Published online by Cambridge University Press:
- 15 May 2009, pp. 435-444
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The rates of decline (half-lives) of maternally acquired antibodies of two different specificities in a group of infants were found to be highly variable, ranging from 18 to 192 days for parainfluenza type 3 antibody (54 infants) and from 15 to 251 days for influenza A2 antibody (nine infants). For antibodies of both specificities approximately 75% of the half-lives were between 15 and 60 days. With parainfluenza type 3 antibody, and possibly with influenza A 2 antibody, the half-lives were inversely proportional to the initial antibody titre of the babies' sera. This relationship could be described by a rectangular hyperbola. Babies with high antibody titres at birth lost this antibody rapidly whereas in babies with low initial titres antibody declined over a longer period.
The half-lives of parainfluenza type 3 antibody and influenza A 2 antibody were compared with that of rubella antibody in the same group of infants (previously published). Maternally acquired viral antibodies of different specificities did not necessarily decline at similar rates in any given child. In nine infants, maternally acquired antibodies of two different specificities (rubella and parainfluenza type 3) declined at significantly different rates in the same child. It is suggested that although the half-life of antibody of a given specificity is related to its concentration in the serum, it is independent of the level of serum antibodies of other specificities.
Star formation in the Small Magellanic Cloud: the youngest star clusters
- E. Sabbi, A. Nota, M. Sirianni, L. R. Carlson, M. Tosi, J. Gallagher, M. Meixner, M. S. Oey, A. Pasquali, L. J. Smith, M. Vlajic, L. Hawks
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- Journal:
- Proceedings of the International Astronomical Union / Volume 2 / Issue S237 / August 2006
- Published online by Cambridge University Press:
- 01 August 2006, pp. 199-203
- Print publication:
- August 2006
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We recently launched a comprehensive ground based (ESO/VLT/NTT) and space (HST & SST) study of the present and past star formation in the Small Magellanic Cloud (SMC), in clusters and in the field, with the goal of understanding how star and cluster formation occur and propagate in an environment of low metallicity, with a gas and dust content that is significantly lower than in the Milky Way. In this paper, we present some preliminary results of the “young cluster” program, where we acquired deep F555W (~V), and F814W (~I) HST/ACS images of the four young and massive SMC star clusters: NGC 346, NGC 602, NGC 299, and NGC 376.