48 results
TRAILBLAZER-ALZ 4: Topline Study Results Directly Comparing Donanemab to Aducanumab on Amyloid Lowering in Early, Symptomatic Alzheimer's Disease
- Stephen Salloway, Elly Lee, Michelle Papka, Andrew Pain, Ena Oru, Margaret B. Ferguson, Hong Wang, Michael Case, Ming Lu, Emily C Collins, Dawn A. Brooks, John Sims
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- Journal:
- BJPsych Open / Volume 9 / Issue S1 / July 2023
- Published online by Cambridge University Press:
- 07 July 2023, p. S67
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Aims
To evaluate the potential superiority of donanemab vs. aducanumab on the percentage of participants with amyloid plaque clearance (≤24.1 Centiloids [CL]) at 6 months in patients with early symptomatic Alzheimer's disease (AD) in phase 3 TRAILBLAZER-ALZ-4 study. The amyloid cascade in AD involves the production and deposition of amyloid beta (Aβ) as an early and necessary event in the pathogenesis of AD.
MethodsParticipants (n = 148) were randomized 1:1 to receive donanemab (700 mg IV Q4W [first 3 doses], then 1400 mg IV Q4W [subsequent doses]) or aducanumab (per USPI: 1 mg/kg IV Q4W [first 2 doses], 3 mg/kg IV Q4W [next 2 doses], 6 mg/kg IV Q4W [next 2 doses] and 10 mg/kg IV Q4W [subsequent doses]).
ResultsBaseline demographics and characteristics were well-balanced across treatment arms (donanemab [N = 71], aducanumab [N = 69]). Twenty-seven donanemab-treated and 28 aducanumab-treated participants defined as having intermediate tau.
Upon assessment of florbetapir F18 PET scans (6 months), 37.9% donanemab-treated vs. 1.6% aducanumab-treated participants achieved amyloid clearance (p < 0.001). In the intermediate tau subpopulation, 38.5% donanemab-treated vs. 3.8% aducanumab-treated participants achieved amyloid clearance (p = 0.008).
Percent change in brain amyloid levels were −65.2%±3.9% (baseline: 98.29 ± 27.83 CL) and −17.0%±4.0% (baseline: 102.40 ± 35.49 CL) in donanemab and aducanumab arms, respectively (p < 0.001). In the intermediate tau subpopulation, percent change in brain amyloid levels were −63.9%±7.4% (baseline: 104.97 ± 25.68 CL) and −25.4%±7.8% (baseline: 102.23 ± 28.13 CL) in donanemab and aducanumab arms, respectively (p ≤ 0.001).
62.0% of donanemab-treated and 66.7% of aducanumab-treated participants reported an adverse event (AE), there were no serious AEs due to ARIA in donanemab arm and 1.4% serious AEs (one event) due to ARIA were reported in aducanumab arm.
ConclusionThis study provides the first active comparator data on amyloid plaque clearance in patients with early symptomatic AD. Significantly higher number of participants reached amyloid clearance and amyloid plaque reductions with donanemab vs. aducanumab at 6 months.
Previously presented at the Clinical Trials on Alzheimer's Disease - 15th Conference, 2022.
A State of Biopreparedness
- Kavita Varshney, Caren Friend, Shopna Bag, Margaret Murphy, Kathy Dempsey, Penelope Clark, Patricia Ferguson
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- Journal:
- Prehospital and Disaster Medicine / Volume 34 / Issue s1 / May 2019
- Published online by Cambridge University Press:
- 06 May 2019, p. s15
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- May 2019
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Introduction:
Westmead Hospital (WMH) recognized gaps in its preparedness to respond to the Ebola 2014 outbreak in West Africa. A fragmented system was identified. A ‘State of Bio-preparedness’ project team convened to discuss all healthcare services in the planning, training, and implementation of a biopreparedness response.
Methods:A survey targeting the staff’s competence and confidence in biologically hazardous infection management was conducted. Semi-structured interviews explored staff members’ experiences and perspectives of biopreparedness response. The collaborative team called “State of Biopreparedness” (SOB) was assembled and a clinical practice improvement project was undertaken. To assess readiness, nine simulated Viral Haemorrhagic Fever (VHF) exercises involving staff and consumers were conducted. These exercises were debriefed by the multidisciplinary committee and themes and issues were identified. These nine simulation drills then assessed readiness and evaluated performance.
Results:A number of consistent issues continue to emerge including:
1. A standard communication pathway for notification was needed - use of the incident paging system (111 pages) to notify the hospital’s incident management team.
2. A consistent and coordinated approach to the training and maintenance of standardized and high-level Personal Protective Equipment (PPE) protocols for frontline clinical and clinical staff was required.
3. Clear delineation of roles and responsibilities and supporting these roles by translating the VHF Control Guideline and policy into task cards and checklists.
4. Strengthening intra- and interdepartmental staff collaboration and communication.
5. Infection control measures to be taken by staff after identifying a patient with possible VHF to reduce the risk of transmission of disease to staff, other patients, and visitors.
Discussion:Integrating disaster management processes with clinical protocols had a positive impact on the hospital’s biopreparedness response. Simulation exercises were a vital and practical way for staff to feel confident and competent to perform their roles.
Food composition tables in resource-poor settings: exploring current limitations and opportunities, with a focus on animal-source foods in sub-Saharan Africa
- Julia de Bruyn, Elaine Ferguson, Margaret Allman-Farinelli, Ian Darnton-Hill, Wende Maulaga, John Msuya, Robyn Alders
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- Journal:
- British Journal of Nutrition / Volume 116 / Issue 10 / 28 November 2016
- Published online by Cambridge University Press:
- 08 November 2016, pp. 1709-1719
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- 28 November 2016
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Animal-source foods (ASF) have the potential to enhance the nutritional adequacy of cereal-based diets in low- and middle-income countries, through the provision of high-quality protein and bioavailable micronutrients. The development of guidelines for including ASF in local diets requires an understanding of the nutrient content of available resources. This article reviews food composition tables (FCT) used in sub-Saharan Africa, examining the spectrum of ASF reported and exploring data sources for each reference. Compositional data are shown to be derived from a small number of existing data sets from analyses conducted largely in high-income nations, often many decades previously. There are limitations in using such values, which represent the products of intensively raised animals of commercial breeds, as a reference in resource-poor settings where indigenous breed livestock are commonly reared in low-input production systems, on mineral-deficient soils and not receiving nutritionally balanced feed. The FCT examined also revealed a lack of data on the full spectrum of ASF, including offal and wild foods, which correspond to local food preferences and represent valuable dietary resources in food-deficient settings. Using poultry products as an example, comparisons are made between compositional data from three high-income nations, and potential implications of differences in the published values for micronutrients of public health significance, including Fe, folate and vitamin A, are discussed. It is important that those working on nutritional interventions and on developing dietary recommendations for resource-poor settings understand the limitations of current food composition data and that opportunities to improve existing resources are more actively explored and supported.
Following A Glittering Trail: Geo-Chemical and Petrographic Characterization of Micaceous Sherds Recovered from Dismal River Sites
- Sarah Trabert, Sunday Eiselt, David V. Hill, Jeffrey Ferguson, Margaret Beck
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- Journal:
- American Antiquity / Volume 81 / Issue 2 / April 2016
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- 20 January 2017, pp. 364-374
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- April 2016
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Protohistoric Ancestral Apache Dismal River groups (A.D. 1600–1750) participated in large exchange networks linking them to other peoples on the Plains and U.S. Southwest. Ceramic vessels made from micaceous materials appear at many Dismal River sites, and micaceous pottery recovered from the Central High Plains is typically seen as evidence for interaction with northern Rio Grande pueblos. However, few mineral or chemical characterization analyses have been conducted on these ceramics, and the term “micaceous” has been applied to a broad range of vessel types regardless of the form, size, or amount of mica in their pastes. Our recent analyses, including macroscopic evaluation combined with petrography and neutron activation analyses (NAA), indicate that only a small subset of Dismal River sherds are derived from New Mexico clays. The rest were likely manufactured using materials from Colorado and Wyoming. Seasonal mobility patterns may have given Dismal River potters the opportunity to collect mica raw materials as they traveled between the Central Plains and Front Range, and this has implications for the importance of internal Plains social networks during the Protohistoric and Historic periods.
Presidential Address 2015—Negotiating Sites of Memory
- Margaret Ferguson
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- PMLA / Publications of the Modern Language Association of America / Volume 130 / Issue 3 / May 2015
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- 23 October 2020, pp. 546-565
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- May 2015
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This text was written as a talk for a particular occasion, the Presidential Address on 9 January 2015 during the MLA Annual Convention in Vancouver, British Columbia. I have not removed the traces of this occasion from the text because they are integral to its argument about sites of memory. I hope my readers will imagine themselves as auditors gathered in a large room in the West Building of the Vancouver Convention Centre, built on the edge of a waterway called Burrard Inlet (fig. 1). That waterway, which is represented in several of the images that accompany this text, had—and still has—a different name in the languages of the indigenous peoples who have inhabited the Vancouver area since before it became part of an American hemisphere. Names, in languages that are ancient but also modern, are a key topic in the reflections that follow.
I'm grateful to you for the gift of your time. Though my talk explores a view of historical time as a multidirectional and multidimensional phenomenon, I'm aware that our shared time in this room goes in one direction in the simple sense that we'll all be older when this session ends, and probably even more hungry, thirsty, and tired than we are now. I've found that the MLA convention sometimes feels like a memory marathon, with special testings of the brain muscles that allow us to recognize faces and recall the first and last names of acquaintances, and even of good friends, whom we haven't seen for a while. Such experiences of remembering and forgetting contributed to my decision to focus on the MLA itself as one of the two sites of memory I want to explore with you this evening. The other site I want to think about is Vancouver, the place where we are now: a modern city built on a site where humans have been living for the last eight to ten millennia (Carlson 12-16).
Editor's Column—Remembering Patsy Yaeger: Her Work and Its Influence
- Simon Gikandi, Marianne Hirsch, Jennifer Wenzel, Margaret W. Ferguson, Marah Gubar, Joseph Allen Boone, Sidonie Smith, Katherine Henninger, Marjorie Levinson
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- PMLA / Publications of the Modern Language Association of America / Volume 130 / Issue 2 / March 2015
- Published online by Cambridge University Press:
- 23 October 2020, pp. 219-235
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- March 2015
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- By Frank Andrasik, Melissa R. Andrews, Ana Inés Ansaldo, Evangelos G. Antzoulatos, Lianhua Bai, Ellen Barrett, Linamara Battistella, Nicolas Bayle, Michael S. Beattie, Peter J. Beek, Serafin Beer, Heinrich Binder, Claire Bindschaedler, Sarah Blanton, Tasia Bobish, Michael L. Boninger, Joseph F. Bonner, Chadwick B. Boulay, Vanessa S. Boyce, Anna-Katharine Brem, Jacqueline C. Bresnahan, Floor E. Buma, Mary Bartlett Bunge, John H. Byrne, Jeffrey R. Capadona, Stefano F. Cappa, Diana D. Cardenas, Leeanne M. Carey, S. Thomas Carmichael, Glauco A. P. Caurin, Pablo Celnik, Kimberly M. Christian, Stephanie Clarke, Leonardo G. Cohen, Adriana B. Conforto, Rory A. Cooper, Rosemarie Cooper, Steven C. Cramer, Armin Curt, Mark D’Esposito, Matthew B. Dalva, Gavriel David, Brandon Delia, Wenbin Deng, Volker Dietz, Bruce H. Dobkin, Marco Domeniconi, Edith Durand, Tracey Vause Earland, Georg Ebersbach, Jonathan J. Evans, James W. Fawcett, Uri Feintuch, Toby A. Ferguson, Marie T. Filbin, Diasinou Fioravante, Itzhak Fischer, Agnes Floel, Herta Flor, Karim Fouad, Richard S. J. Frackowiak, Peter H. Gorman, Thomas W. Gould, Jean-Michel Gracies, Amparo Gutierrez, Kurt Haas, C.D. Hall, Hans-Peter Hartung, Zhigang He, Jordan Hecker, Susan J. Herdman, Seth Herman, Leigh R. Hochberg, Ahmet Höke, Fay B. Horak, Jared C. Horvath, Richard L. Huganir, Friedhelm C. Hummel, Beata Jarosiewicz, Frances E. Jensen, Michael Jöbges, Larry M. Jordan, Jon H. Kaas, Andres M. Kanner, Noomi Katz, Matthew S. Kayser, Annmarie Kelleher, Gerd Kempermann, Timothy E. Kennedy, Jürg Kesselring, Fary Khan, Rachel Kizony, Jeffery D. Kocsis, Boudewijn J. Kollen, Hubertus Köller, John W. Krakauer, Hermano I. Krebs, Gert Kwakkel, Bradley Lang, Catherine E. Lang, Helmar C. Lehmann, Angelo C. Lepore, Glenn S. Le Prell, Mindy F. Levin, Joel M. Levine, David A. Low, Marilyn MacKay-Lyons, Jeffrey D. Macklis, Margaret Mak, Francine Malouin, William C. Mann, Paul D. Marasco, Christopher J. Mathias, Laura McClure, Jan Mehrholz, Lorne M. Mendell, Robert H. Miller, Carol Milligan, Beth Mineo, Simon W. Moore, Jennifer Morgan, Charbel E-H. Moussa, Martin Munz, Randolph J. Nudo, Joseph J. Pancrazio, Theresa Pape, Alvaro Pascual-Leone, Kristin M. Pearson-Fuhrhop, P. Hunter Peckham, Tamara L. Pelleshi, Catherine Verrier Piersol, Thomas Platz, Marcus Pohl, Dejan B. Popović, Andrew M. Poulos, Maulik Purohit, Hui-Xin Qi, Debbie Rand, Mahendra S. Rao, Josef P. Rauschecker, Aimee Reiss, Carol L. Richards, Keith M. Robinson, Melvyn Roerdink, John C. Rosenbek, Serge Rossignol, Edward S. Ruthazer, Arash Sahraie, Krishnankutty Sathian, Marc H. Schieber, Brian J. Schmidt, Michael E. Selzer, Mijail D. Serruya, Himanshu Sharma, Michael Shifman, Jerry Silver, Thomas Sinkjær, George M. Smith, Young-Jin Son, Tim Spencer, John D. Steeves, Oswald Steward, Sheela Stuart, Austin J. Sumner, Chin Lik Tan, Robert W. Teasell, Gareth Thomas, Aiko K. Thompson, Richard F. Thompson, Wesley J. Thompson, Erika Timar, Ceri T. Trevethan, Christopher Trimby, Gary R. Turner, Mark H. Tuszynski, Erna A. van Niekerk, Ricardo Viana, Difei Wang, Anthony B. Ward, Nick S. Ward, Stephen G. Waxman, Patrice L. Weiss, Jörg Wissel, Steven L. Wolf, Jonathan R. Wolpaw, Sharon Wood-Dauphinee, Ross D. Zafonte, Binhai Zheng, Richard D. Zorowitz
- Edited by Michael Selzer, Stephanie Clarke, Leonardo Cohen, Gert Kwakkel, Robert Miller, Case Western Reserve University, Ohio
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- Textbook of Neural Repair and Rehabilitation
- Published online:
- 05 May 2014
- Print publication:
- 24 April 2014, pp ix-xvi
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- By Frank Andrasik, Melissa R. Andrews, Ana Inés Ansaldo, Evangelos G. Antzoulatos, Lianhua Bai, Ellen Barrett, Linamara Battistella, Nicolas Bayle, Michael S. Beattie, Peter J. Beek, Serafin Beer, Heinrich Binder, Claire Bindschaedler, Sarah Blanton, Tasia Bobish, Michael L. Boninger, Joseph F. Bonner, Chadwick B. Boulay, Vanessa S. Boyce, Anna-Katharine Brem, Jacqueline C. Bresnahan, Floor E. Buma, Mary Bartlett Bunge, John H. Byrne, Jeffrey R. Capadona, Stefano F. Cappa, Diana D. Cardenas, Leeanne M. Carey, S. Thomas Carmichael, Glauco A. P. Caurin, Pablo Celnik, Kimberly M. Christian, Stephanie Clarke, Leonardo G. Cohen, Adriana B. Conforto, Rory A. Cooper, Rosemarie Cooper, Steven C. Cramer, Armin Curt, Mark D’Esposito, Matthew B. Dalva, Gavriel David, Brandon Delia, Wenbin Deng, Volker Dietz, Bruce H. Dobkin, Marco Domeniconi, Edith Durand, Tracey Vause Earland, Georg Ebersbach, Jonathan J. Evans, James W. Fawcett, Uri Feintuch, Toby A. Ferguson, Marie T. Filbin, Diasinou Fioravante, Itzhak Fischer, Agnes Floel, Herta Flor, Karim Fouad, Richard S. J. Frackowiak, Peter H. Gorman, Thomas W. Gould, Jean-Michel Gracies, Amparo Gutierrez, Kurt Haas, C.D. Hall, Hans-Peter Hartung, Zhigang He, Jordan Hecker, Susan J. Herdman, Seth Herman, Leigh R. Hochberg, Ahmet Höke, Fay B. Horak, Jared C. Horvath, Richard L. Huganir, Friedhelm C. Hummel, Beata Jarosiewicz, Frances E. Jensen, Michael Jöbges, Larry M. Jordan, Jon H. Kaas, Andres M. Kanner, Noomi Katz, Matthew S. Kayser, Annmarie Kelleher, Gerd Kempermann, Timothy E. Kennedy, Jürg Kesselring, Fary Khan, Rachel Kizony, Jeffery D. Kocsis, Boudewijn J. Kollen, Hubertus Köller, John W. Krakauer, Hermano I. Krebs, Gert Kwakkel, Bradley Lang, Catherine E. Lang, Helmar C. Lehmann, Angelo C. Lepore, Glenn S. Le Prell, Mindy F. Levin, Joel M. Levine, David A. Low, Marilyn MacKay-Lyons, Jeffrey D. Macklis, Margaret Mak, Francine Malouin, William C. Mann, Paul D. Marasco, Christopher J. Mathias, Laura McClure, Jan Mehrholz, Lorne M. Mendell, Robert H. Miller, Carol Milligan, Beth Mineo, Simon W. Moore, Jennifer Morgan, Charbel E-H. Moussa, Martin Munz, Randolph J. Nudo, Joseph J. Pancrazio, Theresa Pape, Alvaro Pascual-Leone, Kristin M. Pearson-Fuhrhop, P. Hunter Peckham, Tamara L. Pelleshi, Catherine Verrier Piersol, Thomas Platz, Marcus Pohl, Dejan B. Popović, Andrew M. Poulos, Maulik Purohit, Hui-Xin Qi, Debbie Rand, Mahendra S. Rao, Josef P. Rauschecker, Aimee Reiss, Carol L. Richards, Keith M. Robinson, Melvyn Roerdink, John C. Rosenbek, Serge Rossignol, Edward S. Ruthazer, Arash Sahraie, Krishnankutty Sathian, Marc H. Schieber, Brian J. Schmidt, Michael E. Selzer, Mijail D. Serruya, Himanshu Sharma, Michael Shifman, Jerry Silver, Thomas Sinkjær, George M. Smith, Young-Jin Son, Tim Spencer, John D. Steeves, Oswald Steward, Sheela Stuart, Austin J. Sumner, Chin Lik Tan, Robert W. Teasell, Gareth Thomas, Aiko K. Thompson, Richard F. Thompson, Wesley J. Thompson, Erika Timar, Ceri T. Trevethan, Christopher Trimby, Gary R. Turner, Mark H. Tuszynski, Erna A. van Niekerk, Ricardo Viana, Difei Wang, Anthony B. Ward, Nick S. Ward, Stephen G. Waxman, Patrice L. Weiss, Jörg Wissel, Steven L. Wolf, Jonathan R. Wolpaw, Sharon Wood-Dauphinee, Ross D. Zafonte, Binhai Zheng, Richard D. Zorowitz
- Edited by Michael E. Selzer, Stephanie Clarke, Leonardo G. Cohen, Gert Kwakkel, Robert H. Miller, Case Western Reserve University, Ohio
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- Textbook of Neural Repair and Rehabilitation
- Published online:
- 05 June 2014
- Print publication:
- 24 April 2014, pp ix-xvi
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- By Ioannis P. Androulakis, Djillali Annane, Gérard Audibert, Lisa L. Barnes, Paolo Bartolomeo, Walter S. Bartynski, David A. Bennett, Nicolas Bruder, Nathan E. Brummel, Steve E. Calvano, Alain Cariou, F. Chretien, Jan Claassen, Colm Cunningham, Souhayl Dahmani, Robert Dantzer, Dimitry S. Davydow, Sanjay V. Desai, E. Wesley Ely, Frédéric Faugeras, Karen J. Ferguson, Brandon Foreman, Sadanand M. Gaikwad, Rebecca F. Gottesman, Maura A. Grega, Richard D. Griffiths, Marion Griton, Stefan D. Gurney, Hebah M. Hefzy, Michael T. Heneka, Dustin M. Hipp, Ramona O. Hopkins, Christopher G. Hughes, James C. Jackson, Christina Jones, Peter W. Kaplan, Keith W. Kelley, Raymond C. Koehler, Matthew A. Koenig, Jan Pieter Konsman, Felix Kork, John P. Kress, Stephen F. Lowry, Alawi Luetz, David Luis, Alasdair M. J. MacLullich, Guy M. McKhann, Jean Mantz, Panteleimon D. Mavroudis, Mervyn Maze, Bruno Mégarbane, Lionel Naccache, Dale M. Needham, Pratik P. Pandharipande, Jean-Francois Payen, V. Hugh Perry, Margaret Pisani, C. Rauturier, Benjamin Rohaut, Jennifer Ryan, Robert D. Sanders, Jeremy D. Scheff, Frederic Sedel, Ola A. Selnes, Tarek Sharshar, Martin Siegemund, Yoanna Skrobik, Jamie W. Sleigh, Romain Sonneville, Claudia D. Spies, Luzius A. Steiner, Robert D. Stevens, Raoul Sutter, Fabio Silvio Taccone, Richard E. Temes, Willem A. van Gool, Christel C. Vanbesien, F. Verdonk, Odile Viltart, Julia Wendon, Catherine N. Widmann, Robert S. Wilson
- Edited by Robert D. Stevens, Tarek Sharshar, E. Wesley Ely, Vanderbilt University, Tennessee
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- Brain Disorders in Critical Illness
- Published online:
- 05 October 2013
- Print publication:
- 19 September 2013, pp viii-xii
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Examining the Production and Distribution of Shivwits Ware Pottery in the American Southwest
- Karen G. Harry, Timothy J. Ferguson, James R. Allison, Brett T. McLaurin, Jeff Ferguson, Margaret Lyneis
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- Journal:
- American Antiquity / Volume 78 / Issue 2 / April 2013
- Published online by Cambridge University Press:
- 20 January 2017, pp. 385-396
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- April 2013
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Compositional analyses were undertaken to evaluate the hypothesis that Shivwits Ware pottery found in southern Nevada was not produced in that area but, instead, manufactured on the Shivwits Plateau. The evidence supports this hypothesis and indicates that large quantities of Shivwits Ware jars moved through a distribution system linking the upland areas of the western Arizona Strip with the lowlands of southeastern Nevada. This long-distance movement of utilitarian pottery is unusual for precontact North America, in that it occurred in the apparent absence of any centralized distribution mechanisms and between what would have been small, kin-based communities. The nature and the causes for the development of this distribution system are discussed.
State-Level Measures of Institutional Budgetary Influence from the American State Administrators Project: 1964–98
- Nelson C. Dometrius, Cynthia Bowling, Margaret R. Ferguson, Deil S. Wright
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- Journal:
- State Politics & Policy Quarterly / Volume 13 / Issue 1 / March 2013
- Published online by Cambridge University Press:
- 25 January 2021, pp. 107-120
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- March 2013
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The American State Administrators Project is a half-century long research program surveying the attitudes and behavior of state agency leaders. The project has produced a voluminous number of publications and conference papers. At the same time it has also faced several difficulties in making its data more widely available to the scholarly community. This paper describes the Project, some of the data difficulties it has faced, and the portion of the data being distributed with this article.
The Letter of Recommendation as Strange Work
- Margaret Ferguson
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- Journal:
- PMLA / Publications of the Modern Language Association of America / Volume 127 / Issue 4 / October 2012
- Published online by Cambridge University Press:
- 23 October 2020, pp. 954-962
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- October 2012
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On the one hand, the gift presents itself as a radical Other of the commodity—and therefore also of work, insofar as the latter is understood as an investment of time and energy made in the expectation of wages or profit. On the other hand, the idea of the gift seems constantly to be drawn back under the horizon of rational exchange, and to be thus endlessly re-revealed as a secret ally of both work and the Work.
—Scott Cutler Shershow, The Work and the Gift
I have put together all these details to convince you that this recommendation of mine is something out of the common.
Quae ego omnia collegi, ut intellegeres non vulgarem esse commendationem hanc meam.
—Cicero, Epistulae ad familiares, book 13
LAST FALL I FOUND IN MY OFFICE MAILBOX AN ENVELOPE FROM A SOPHOMORE ENGLISH MAJOR WHO HAD ASKED ME DURING THE SUMMER for a last-minute letter of recommendation for a scholarship competition. The envelope contained a handwritten thank-you note—and a gift certificate for a local restaurant. I e-mailed the student to thank her and to tell her that I couldn't accept the gift certificate since the letter I had written for her was part of my job as a teacher. She insisted; I insisted. She said that several teachers had turned her down before I agreed (from a hotel in Germany) to write for her. I felt rueful, as well as grateful to her for the token of gratitude that I couldn't accept. Eventually she won the debate: I accepted the printed piece of paper and took my daughters out to a free lunch.
Contributors
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- By Rose Teteki Abbey, K. C. Abraham, David Tuesday Adamo, LeRoy H. Aden, Efrain Agosto, Victor Aguilan, Gillian T. W. Ahlgren, Charanjit Kaur AjitSingh, Dorothy B E A Akoto, Giuseppe Alberigo, Daniel E. Albrecht, Ruth Albrecht, Daniel O. Aleshire, Urs Altermatt, Anand Amaladass, Michael Amaladoss, James N. Amanze, Lesley G. Anderson, Thomas C. Anderson, Victor Anderson, Hope S. Antone, María Pilar Aquino, Paula Arai, Victorio Araya Guillén, S. Wesley Ariarajah, Ellen T. Armour, Brett Gregory Armstrong, Atsuhiro Asano, Naim Stifan Ateek, Mahmoud Ayoub, John Alembillah Azumah, Mercedes L. García Bachmann, Irena Backus, J. Wayne Baker, Mieke Bal, Lewis V. Baldwin, William Barbieri, António Barbosa da Silva, David Basinger, Bolaji Olukemi Bateye, Oswald Bayer, Daniel H. Bays, Rosalie Beck, Nancy Elizabeth Bedford, Guy-Thomas Bedouelle, Chorbishop Seely Beggiani, Wolfgang Behringer, Christopher M. Bellitto, Byard Bennett, Harold V. Bennett, Teresa Berger, Miguel A. Bernad, Henley Bernard, Alan E. Bernstein, Jon L. Berquist, Johannes Beutler, Ana María Bidegain, Matthew P. Binkewicz, Jennifer Bird, Joseph Blenkinsopp, Dmytro Bondarenko, Paulo Bonfatti, Riet en Pim Bons-Storm, Jessica A. Boon, Marcus J. Borg, Mark Bosco, Peter C. Bouteneff, François Bovon, William D. Bowman, Paul S. Boyer, David Brakke, Richard E. Brantley, Marcus Braybrooke, Ian Breward, Ênio José da Costa Brito, Jewel Spears Brooker, Johannes Brosseder, Nicholas Canfield Read Brown, Robert F. Brown, Pamela K. Brubaker, Walter Brueggemann, Bishop Colin O. Buchanan, Stanley M. Burgess, Amy Nelson Burnett, J. Patout Burns, David B. Burrell, David Buttrick, James P. Byrd, Lavinia Byrne, Gerado Caetano, Marcos Caldas, Alkiviadis Calivas, William J. Callahan, Salvatore Calomino, Euan K. Cameron, William S. Campbell, Marcelo Ayres Camurça, Daniel F. Caner, Paul E. Capetz, Carlos F. Cardoza-Orlandi, Patrick W. Carey, Barbara Carvill, Hal Cauthron, Subhadra Mitra Channa, Mark D. Chapman, James H. Charlesworth, Kenneth R. Chase, Chen Zemin, Luciano Chianeque, Philip Chia Phin Yin, Francisca H. Chimhanda, Daniel Chiquete, John T. Chirban, Soobin Choi, Robert Choquette, Mita Choudhury, Gerald Christianson, John Chryssavgis, Sejong Chun, Esther Chung-Kim, Charles M. A. Clark, Elizabeth A. Clark, Sathianathan Clarke, Fred Cloud, John B. Cobb, W. Owen Cole, John A Coleman, John J. Collins, Sylvia Collins-Mayo, Paul K. Conkin, Beth A. Conklin, Sean Connolly, Demetrios J. Constantelos, Michael A. Conway, Paula M. Cooey, Austin Cooper, Michael L. Cooper-White, Pamela Cooper-White, L. William Countryman, Sérgio Coutinho, Pamela Couture, Shannon Craigo-Snell, James L. Crenshaw, David Crowner, Humberto Horacio Cucchetti, Lawrence S. Cunningham, Elizabeth Mason Currier, Emmanuel Cutrone, Mary L. Daniel, David D. Daniels, Robert Darden, Rolf Darge, Isaiah Dau, Jeffry C. Davis, Jane Dawson, Valentin Dedji, John W. de Gruchy, Paul DeHart, Wendy J. 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Yee, Viktor Yelensky, Yeo Khiok-Khng, Gustav K. K. Yeung, Angela Yiu, Amos Yong, Yong Ting Jin, You Bin, Youhanna Nessim Youssef, Eliana Yunes, Robert Michael Zaller, Valarie H. Ziegler, Barbara Brown Zikmund, Joyce Ann Zimmerman, Aurora Zlotnik, Zhuo Xinping
- Edited by Daniel Patte, Vanderbilt University, Tennessee
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- The Cambridge Dictionary of Christianity
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- 05 August 2012
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- 20 September 2010, pp xi-xliv
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Deil S. Wright
- Nelson C. Dometrius, Cynthia J. Bowling, Jeffrey L. Brudney, Chung-Lae Cho, Margaret R. Ferguson, Alfred R. (Fred) Light, Jay Eungha Ryu
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- PS: Political Science & Politics / Volume 42 / Issue 4 / October 2009
- Published online by Cambridge University Press:
- 25 September 2009, pp. 790-792
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- October 2009
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Deil Spencer Wright, Alumni Distinguished Professor Emeritus at the University of North Carolina at Chapel Hill, passed away on June 30 2009, at the age of 79. Born on June 18, 1930, in Three Rivers, Michigan, to working-class parents, Deil received his BA, MPA, and Ph.D. from the University of Michigan at Ann Arbor. He spent time on the faculties of Wayne State University, the University of Iowa, and the University of California at Berkeley before landing at the University of North Carolina at Chapel Hill for the bulk of his career.
The Diets of Labouring Class Families during the course of the War
- Margaret Ferguson
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- Journal of Hygiene / Volume 18 / Issue 4 / February 1920
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- 15 May 2009, pp. 409-416
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1. Throughout the war the food value of the dietaries investigated with one exception showed great constancy, temporary shortage of certain commodities being compensated for by the greater use of others, especially of flour.
2. The food consumed was determined much more by the income and dietary habits of the families than by the restrictions imposed by rationing. The marked variations in the energy value of one dietary from time to time (normally a generous one) were directly caused by changes of income.
3. The children of three families were markedly below the average in height and weight. As the energy available in the food of these families only averaged 40 per cent. above their basal requirements calculated according to age and body surface, it seems probable that the interruption of growth had been caused by an insufficient supply of food.
4. A fourth family had at two periods of study an equally low intake of energy, but during the other two studies had at least 100 per cent. above the basal energy requirements. As the children were normal in development, growth was apparently unchecked by the temporary periods of food shortage.
Characterization and mapping of a viable anaemic mutant in the mouse: a new allele, mkvan, at the microcytic anaemia locus
- Sunil Handa, Janet M. Ferguson, Margaret E. Wallace, Grahame Bulfield
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- Genetical Research / Volume 51 / Issue 1 / February 1988
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- 14 April 2009, pp. 41-45
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A viable anaemic mouse mutant arose in the stock of a mouse fancier and has been characterized haematologically and genetically. Anaemic animals were less viable than normal animals (especially from 0 to 2 weeks of age) and had lower haemoglobin levels, percentage packed-cell volumes, higher red cell counts and lower mean cell volume than normal animals. Peripheral blood films showed a wide range of abnormal cells and extreme microcytosis. Linkage studies showed the mutant to be linked to the chromosome 15 markers Na Ca and bt; recombination with Ca was 1·37 ± 0·68 % for females and 10·5 ± 7·41 % for males. This position is similar to the microcytic anaemia, mk, mutant, and crosses between the viable anaemia mutation and mk/mk homozygotes showed the two to be allelic. Viable anaemia is therefore a second allele at the mk locus mkvan; new data give its position on chromosome 15.
Kate Chedgzoy. Women's Writing in the British Atlantic World: Memory, Place and History, 1550–1700. Cambridge: Cambridge University Press, 2007. viii + 268 pp. index. bibl. $95. ISBN: 978–0–521–88098–5.
- Margaret Ferguson
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- Renaissance Quarterly / Volume 62 / Issue 1 / Spring 2009
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- 20 November 2018, pp. 303-304
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- Spring 2009
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eight - Communicating in divorced families
- Neil Ferguson
- With Gillian Douglas, Nigel Lowe, Mervyn Murch, Margaret Robinson
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- Grandparenting in Divorced Families
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- Bristol University Press
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- 20 January 2022
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- 07 January 2004, pp 79-88
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Summary
Introduction
This chapter explores how, and to what extent, the three generations in our group of divorced families communicated with each other about marriage breakdown and its consequences. First, it looks at the way that parents warned their own parents about their impending separation, and then investigates what the grandchildren told their mothers, fathers and grandparents about their relationships with the ‘other side’ of their divided families. The chapter also investigates whether or not children were used as conduits for the flow of information between the two sides of the divorced family.
Telling grandparents about the planned separation
Although grandparents were not asked directly when and how they were told about the breakdown of their child’s marriage, the interview guide included questions about their relationships with grandchildren before and after the separation. Almost half the grandparents interviewed mentioned their surprise at learning of their child’s separation. It was common for parents to hide their marriage problems from their own parents and the news of the separation often came as a shock to grandparents. Parents admitted that they were reluctant to take grandparents into their confidence, but their explanations made it clear that this was neither symptomatic of a lack of affection nor a failure to anticipate the likely effects of their separation on the wider family. A rather similar conclusion, it may be recalled, was made as a result of the investigation of children’s reluctance to confide in their grandparents when they felt upset or worried about family break-up (see Chapter Three).
The deliberate concealment of problems might be interpreted as evidence that parents did not consider grandparents to be involved. However, divorced couples were also concerned about disappointing their parents; they were worried about invoking their displeasure and anxious to protect them from the pain of their divorce – feelings that are characteristic of many parent–child relationships. The interview data revealed that most mothers had worried needlessly and were pleasantly surprised by their parents’ reactions to being told that the marriage had ended. For example, Alfie’s mother recalled:
Really, my parents could have said to me, ‘What are you doing, splitting up? This is so wrong! Don’t be ridiculous! For goodness sake, pull yourself together!’ . But they listened to what I had to say. And, rightly or wrongly, they love me and they told me so.
three - Grandparents’ relationships with grandchildren: continuity and change
- Neil Ferguson
- With Gillian Douglas, Nigel Lowe, Mervyn Murch, Margaret Robinson
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- Grandparenting in Divorced Families
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- Bristol University Press
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- 20 January 2022
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- 07 January 2004, pp 21-32
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Summary
A changing relationship
In Chapter Two, we discussed some of the factors that previous studies have indicated influence the nature of grandparents’ relationships with their grandchildren. In this chapter, we ask: ‘What importance do grandchildren attach to their relationship with their grandparents and how might these relationships be affected by divorce? And, ‘is there evidence of continuity in the grandparent–grandchild relationship in divorced families as well as evidence of change as the result of family break-up?’.
Grandparent’s relationships with their grandchildren
The studies reviewed in Chapter Two made it clear that grandparent age is related to the frequency of grandparents’ contact with their grandchildren and that older grandchildren have less contact with their grandparents. But does this mean that they are not as emotionally close to their grandparents? Here, we begin by considering the views of some teenage grandchildren and their feelings about their grandparents. They reported that they have close relationships with their grandparents, but this assertion was often accompanied by apparently contradictory evidence of a growing emotional distance. Being ‘close to grandparents’ could mean seeing them regularly, enjoying their company, sharing intimacies and expressing affection. However, we discovered that the phrase need not imply anything about frequency of contact and was used on occasion to mean ‘nurturing positive feelings’. Evidence from divorced parents suggested that older grandchildren saw their grandparents less frequently than their younger brothers and sisters. Mothers, we discovered, occasionally reminded their children that they had not seen their grandparents for some time and persuaded them to accompany them on a visit to their grandparents’ home. They reported a gradual reduction in their children’s contact with their grandparents. Most felt that this did not mean that relationships could no longer be described as ‘close’ or that grandchildren and grandparents felt less affection for each other. It was, in parents’ opinions, understandable that the relationship should change.
Alfie’s mother had been separated for two years before her decree nisi was granted over four years ago. She had a particularly close relationship with her parents who lived about a mile away and had been very supportive of her and her three children, aged 12, 16 and 18. She commented that the maternal grandparents’ ‘unconditional love’ had taught her a lot about bringing up her own children.
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