17 results
Implementation of the Targeted Assessment for Prevention Strategy in a healthcare system to reduce Clostridioides difficile infection rates
- Katelyn A. White, Minn M. Soe, Amy Osborn, Christie Walling, Lucy V. Fike, Carolyn V. Gould, David T. Kuhar, Jonathan R. Edwards, Ronda L. Cochran
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- Journal:
- Infection Control & Hospital Epidemiology / Volume 41 / Issue 3 / March 2020
- Published online by Cambridge University Press:
- 13 January 2020, pp. 295-301
- Print publication:
- March 2020
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Background:
Prevention of Clostridioides difficile infection (CDI) is a national priority and may be facilitated by deployment of the Targeted Assessment for Prevention (TAP) Strategy, a quality improvement framework providing a focused approach to infection prevention. This article describes the process and outcomes of TAP Strategy implementation for CDI prevention in a healthcare system.
Methods:Hospital A was identified based on CDI surveillance data indicating an excess burden of infections above the national goal; hospitals B and C participated as part of systemwide deployment. TAP facility assessments were administered to staff to identify infection control gaps and inform CDI prevention interventions. Retrospective analysis was performed using negative-binomial, interrupted time series (ITS) regression to assess overall effect of targeted CDI prevention efforts. Analysis included hospital-onset, laboratory-identified C. difficile event data for 18 months before and after implementation of the TAP facility assessments.
Results:The systemwide monthly CDI rate significantly decreased at the intervention (β2, −44%; P = .017), and the postintervention CDI rate trend showed a sustained decrease (β1 + β3; −12% per month; P = .008). At an individual hospital level, the CDI rate trend significantly decreased in the postintervention period at hospital A only (β1 + β3, −26% per month; P = .003).
Conclusions:This project demonstrates TAP Strategy implementation in a healthcare system, yielding significant decrease in the laboratory-identified C. difficile rate trend in the postintervention period at the system level and in hospital A. This project highlights the potential benefit of directing prevention efforts to facilities with the highest burden of excess infections to more efficiently reduce CDI rates.
Response of Selected Soybean (Glycine max) Cultivars to Dimethenamid and Metolachlor in Hydroponic Conditions
- Bradley T. Osborne, David R. Shaw, Randall L. Ratliff
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- Journal:
- Weed Technology / Volume 9 / Issue 1 / March 1995
- Published online by Cambridge University Press:
- 12 June 2017, pp. 178-181
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Soybean cultivars were grown in a hydroponic culture to evaluate tolerance to dimethenamid and metolachlor. Root length was reduced in 7 of the 32 cultivars with 50 ppb dimethenamid. ‘Asgrow 5403’ and ‘Bryan’ root lengths were reduced more than 20%. ‘Asgrow 6297’ was the only cultivar with greater than 12% root length reductions with 83 ppb metolachlor. The longest lateral root of all cultivars was shortened with dimethenamid. ‘NK-1460’ and Bryan expressed the most lateral root length reduction, at 73 and 62%, respectively. Asgrow 6297 was tolerant to dimethenamid, but lateral roots were reduced 16%. Metolachlor reduced the lateral root lengths of 12 cultivars, with Asgrow 5403, ‘Coker 6955,’ and Bryan reduced more than 20%. Bryan was the most sensitive cultivar to both herbicides, while ‘Brim’ was the most tolerant of cultivars evaluated.
Soybean (Glycine Max) Cultivar Tolerance to San 582H and Metolachlor As Influenced by Soil Moisture
- Bradley T. Osborne, David R. Shaw, Randall L. Ratliff
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- Journal:
- Weed Science / Volume 43 / Issue 2 / June 1995
- Published online by Cambridge University Press:
- 12 June 2017, pp. 288-292
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Field experiments were conducted in 1991 and 1992 to evaluate differential soybean cultivar tolerance to SAN 582H and metolachlor applied PRE, as influenced by soil moisture. Eighteen d after planting, a 3× rate of SAN 582H (3.0 kg ai ha−1) reduced plant populations of ‘Wright,’ ‘Bedford,’ and ‘Stonewall’ and metolachlor did not. At leaf drop, neither herbicide reduced crop height with optimum moisture. With excessive moisture, 3× rates of SAN 582H reduced plant height of Wright, Bedford, ‘Walters,’ ‘Young,’ ‘Brim,’ and ‘Bryan,’ and metolachlor reduced height of ‘Sharkey.’ The greatest yield reductions were due to excessive moisture, regardless of herbicide. Neither herbicide reduced yields with optimum moisture nor did a 1× rate with excessive moisture. However, with excessive moisture, a 3× rate of metolachlor (5.0 kg ai ha−1) reduced yield of Bedford by 470 kg ha−1, and the 3× rate of SAN 582H reduced yield of ‘Rhodes,’ Walters, and ‘Centennial’ more than 500 kg ha−1. Overall, soybean tolerance to both herbicides was good, but if used above recommended rates and with excessive moisture, injury can occur.
Notes on Contributors
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- By David Amigoni, Mark Asquith, Jane Bownas, Adelene Buckland, Carolyn Burdett, Pamela Dalziel, Christine DeVine, Tim Dolin, Roger Ebbatson, Trish Ferguson, Shanyn Fiske, Simon Gatrell, Sophie Gilmartin, William Greenslade, Ann Heilmann, Michael Herbert, John Hughes, Rena Jackson, Elizabeth Langland, Sarah E. Maier, Phillip Mallett, Francesco Marroni, Jane Mattisson, Andrew Nash, K. M. Newton, Francis O’Gorman, John Osborne, Patrick Parrinder, Andrew Radford, Fred Reid, Angelique Richardson, Mary Rimmer, Peter Robinson, Dennis Taylor, Jenny Bourne, Jane Thomas, Herbert F. Tucker, Norman Vance, Roger Webster, Rebecca Welshman, Glen Wickens, Melanie Williams, Keith Wilson, T. R. Wright
- Edited by Phillip Mallett, University of St Andrews, Scotland
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- Thomas Hardy in Context
- Published online:
- 05 February 2013
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- 18 March 2013, pp ix-xvi
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- By Rose Teteki Abbey, K. C. Abraham, David Tuesday Adamo, LeRoy H. Aden, Efrain Agosto, Victor Aguilan, Gillian T. W. Ahlgren, Charanjit Kaur AjitSingh, Dorothy B E A Akoto, Giuseppe Alberigo, Daniel E. Albrecht, Ruth Albrecht, Daniel O. Aleshire, Urs Altermatt, Anand Amaladass, Michael Amaladoss, James N. Amanze, Lesley G. Anderson, Thomas C. Anderson, Victor Anderson, Hope S. Antone, María Pilar Aquino, Paula Arai, Victorio Araya Guillén, S. Wesley Ariarajah, Ellen T. Armour, Brett Gregory Armstrong, Atsuhiro Asano, Naim Stifan Ateek, Mahmoud Ayoub, John Alembillah Azumah, Mercedes L. García Bachmann, Irena Backus, J. Wayne Baker, Mieke Bal, Lewis V. Baldwin, William Barbieri, António Barbosa da Silva, David Basinger, Bolaji Olukemi Bateye, Oswald Bayer, Daniel H. Bays, Rosalie Beck, Nancy Elizabeth Bedford, Guy-Thomas Bedouelle, Chorbishop Seely Beggiani, Wolfgang Behringer, Christopher M. Bellitto, Byard Bennett, Harold V. Bennett, Teresa Berger, Miguel A. Bernad, Henley Bernard, Alan E. Bernstein, Jon L. Berquist, Johannes Beutler, Ana María Bidegain, Matthew P. Binkewicz, Jennifer Bird, Joseph Blenkinsopp, Dmytro Bondarenko, Paulo Bonfatti, Riet en Pim Bons-Storm, Jessica A. Boon, Marcus J. Borg, Mark Bosco, Peter C. Bouteneff, François Bovon, William D. Bowman, Paul S. Boyer, David Brakke, Richard E. Brantley, Marcus Braybrooke, Ian Breward, Ênio José da Costa Brito, Jewel Spears Brooker, Johannes Brosseder, Nicholas Canfield Read Brown, Robert F. Brown, Pamela K. Brubaker, Walter Brueggemann, Bishop Colin O. Buchanan, Stanley M. Burgess, Amy Nelson Burnett, J. Patout Burns, David B. Burrell, David Buttrick, James P. Byrd, Lavinia Byrne, Gerado Caetano, Marcos Caldas, Alkiviadis Calivas, William J. Callahan, Salvatore Calomino, Euan K. Cameron, William S. Campbell, Marcelo Ayres Camurça, Daniel F. Caner, Paul E. Capetz, Carlos F. Cardoza-Orlandi, Patrick W. Carey, Barbara Carvill, Hal Cauthron, Subhadra Mitra Channa, Mark D. Chapman, James H. Charlesworth, Kenneth R. Chase, Chen Zemin, Luciano Chianeque, Philip Chia Phin Yin, Francisca H. Chimhanda, Daniel Chiquete, John T. Chirban, Soobin Choi, Robert Choquette, Mita Choudhury, Gerald Christianson, John Chryssavgis, Sejong Chun, Esther Chung-Kim, Charles M. A. Clark, Elizabeth A. Clark, Sathianathan Clarke, Fred Cloud, John B. Cobb, W. Owen Cole, John A Coleman, John J. Collins, Sylvia Collins-Mayo, Paul K. Conkin, Beth A. Conklin, Sean Connolly, Demetrios J. Constantelos, Michael A. Conway, Paula M. Cooey, Austin Cooper, Michael L. Cooper-White, Pamela Cooper-White, L. William Countryman, Sérgio Coutinho, Pamela Couture, Shannon Craigo-Snell, James L. Crenshaw, David Crowner, Humberto Horacio Cucchetti, Lawrence S. Cunningham, Elizabeth Mason Currier, Emmanuel Cutrone, Mary L. Daniel, David D. Daniels, Robert Darden, Rolf Darge, Isaiah Dau, Jeffry C. Davis, Jane Dawson, Valentin Dedji, John W. de Gruchy, Paul DeHart, Wendy J. Deichmann Edwards, Miguel A. De La Torre, George E. Demacopoulos, Thomas de Mayo, Leah DeVun, Beatriz de Vasconcellos Dias, Dennis C. Dickerson, John M. Dillon, Luis Miguel Donatello, Igor Dorfmann-Lazarev, Susanna Drake, Jonathan A. Draper, N. Dreher Martin, Otto Dreydoppel, Angelyn Dries, A. J. Droge, Francis X. D'Sa, Marilyn Dunn, Nicole Wilkinson Duran, Rifaat Ebied, Mark J. Edwards, William H. Edwards, Leonard H. Ehrlich, Nancy L. Eiesland, Martin Elbel, J. Harold Ellens, Stephen Ellingson, Marvin M. Ellison, Robert Ellsberg, Jean Bethke Elshtain, Eldon Jay Epp, Peter C. Erb, Tassilo Erhardt, Maria Erling, Noel Leo Erskine, Gillian R. Evans, Virginia Fabella, Michael A. Fahey, Edward Farley, Margaret A. Farley, Wendy Farley, Robert Fastiggi, Seena Fazel, Duncan S. Ferguson, Helwar Figueroa, Paul Corby Finney, Kyriaki Karidoyanes FitzGerald, Thomas E. FitzGerald, John R. Fitzmier, Marie Therese Flanagan, Sabina Flanagan, Claude Flipo, Ronald B. Flowers, Carole Fontaine, David Ford, Mary Ford, Stephanie A. Ford, Jim Forest, William Franke, Robert M. Franklin, Ruth Franzén, Edward H. Friedman, Samuel Frouisou, Lorelei F. Fuchs, Jojo M. Fung, Inger Furseth, Richard R. Gaillardetz, Brandon Gallaher, China Galland, Mark Galli, Ismael García, Tharscisse Gatwa, Jean-Marie Gaudeul, Luis María Gavilanes del Castillo, Pavel L. Gavrilyuk, Volney P. Gay, Metropolitan Athanasios Geevargis, Kondothra M. George, Mary Gerhart, Simon Gikandi, Maurice Gilbert, Michael J. Gillgannon, Verónica Giménez Beliveau, Terryl Givens, Beth Glazier-McDonald, Philip Gleason, Menghun Goh, Brian Golding, Bishop Hilario M. Gomez, Michelle A. Gonzalez, Donald K. Gorrell, Roy Gottfried, Tamara Grdzelidze, Joel B. Green, Niels Henrik Gregersen, Cristina Grenholm, Herbert Griffiths, Eric W. Gritsch, Erich S. Gruen, Christoffer H. Grundmann, Paul H. Gundani, Jon P. Gunnemann, Petre Guran, Vidar L. Haanes, Jeremiah M. Hackett, Getatchew Haile, Douglas John Hall, Nicholas Hammond, Daphne Hampson, Jehu J. Hanciles, Barry Hankins, Jennifer Haraguchi, Stanley S. Harakas, Anthony John Harding, Conrad L. Harkins, J. William Harmless, Marjory Harper, Amir Harrak, Joel F. Harrington, Mark W. Harris, Susan Ashbrook Harvey, Van A. Harvey, R. Chris Hassel, Jione Havea, Daniel Hawk, Diana L. Hayes, Leslie Hayes, Priscilla Hayner, S. Mark Heim, Simo Heininen, Richard P. Heitzenrater, Eila Helander, David Hempton, Scott H. Hendrix, Jan-Olav Henriksen, Gina Hens-Piazza, Carter Heyward, Nicholas J. Higham, David Hilliard, Norman A. Hjelm, Peter C. Hodgson, Arthur Holder, M. Jan Holton, Dwight N. Hopkins, Ronnie Po-chia Hsia, Po-Ho Huang, James Hudnut-Beumler, Jennifer S. Hughes, Leonard M. Hummel, Mary E. Hunt, Laennec Hurbon, Mark Hutchinson, Susan E. Hylen, Mary Beth Ingham, H. Larry Ingle, Dale T. Irvin, Jon Isaak, Paul John Isaak, Ada María Isasi-Díaz, Hans Raun Iversen, Margaret C. Jacob, Arthur James, Maria Jansdotter-Samuelsson, David Jasper, Werner G. Jeanrond, Renée Jeffery, David Lyle Jeffrey, Theodore W. Jennings, David H. Jensen, Robin Margaret Jensen, David Jobling, Dale A. Johnson, Elizabeth A. Johnson, Maxwell E. Johnson, Sarah Johnson, Mark D. Johnston, F. Stanley Jones, James William Jones, John R. Jones, Alissa Jones Nelson, Inge Jonsson, Jan Joosten, Elizabeth Judd, Mulambya Peggy Kabonde, Robert Kaggwa, Sylvester Kahakwa, Isaac Kalimi, Ogbu U. Kalu, Eunice Kamaara, Wayne C. Kannaday, Musimbi Kanyoro, Veli-Matti Kärkkäinen, Frank Kaufmann, Léon Nguapitshi Kayongo, Richard Kearney, Alice A. Keefe, Ralph Keen, Catherine Keller, Anthony J. Kelly, Karen Kennelly, Kathi Lynn Kern, Fergus Kerr, Edward Kessler, George Kilcourse, Heup Young Kim, Kim Sung-Hae, Kim Yong-Bock, Kim Yung Suk, Richard King, Thomas M. King, Robert M. Kingdon, Ross Kinsler, Hans G. Kippenberg, Cheryl A. Kirk-Duggan, Clifton Kirkpatrick, Leonid Kishkovsky, Nadieszda Kizenko, Jeffrey Klaiber, Hans-Josef Klauck, Sidney Knight, Samuel Kobia, Robert Kolb, Karla Ann Koll, Heikki Kotila, Donald Kraybill, Philip D. W. Krey, Yves Krumenacker, Jeffrey Kah-Jin Kuan, Simanga R. Kumalo, Peter Kuzmic, Simon Shui-Man Kwan, Kwok Pui-lan, André LaCocque, Stephen E. Lahey, John Tsz Pang Lai, Emiel Lamberts, Armando Lampe, Craig Lampe, Beverly J. Lanzetta, Eve LaPlante, Lizette Larson-Miller, Ariel Bybee Laughton, Leonard Lawlor, Bentley Layton, Robin A. Leaver, Karen Lebacqz, Archie Chi Chung Lee, Marilyn J. Legge, Hervé LeGrand, D. L. LeMahieu, Raymond Lemieux, Bill J. Leonard, Ellen M. Leonard, Outi Leppä, Jean Lesaulnier, Nantawan Boonprasat Lewis, Henrietta Leyser, Alexei Lidov, Bernard Lightman, Paul Chang-Ha Lim, Carter Lindberg, Mark R. Lindsay, James R. Linville, James C. Livingston, Ann Loades, David Loades, Jean-Claude Loba-Mkole, Lo Lung Kwong, Wati Longchar, Eleazar López, David W. Lotz, Andrew Louth, Robin W. Lovin, William Luis, Frank D. Macchia, Diarmaid N. J. MacCulloch, Kirk R. MacGregor, Marjory A. MacLean, Donald MacLeod, Tomas S. Maddela, Inge Mager, Laurenti Magesa, David G. Maillu, Fortunato Mallimaci, Philip Mamalakis, Kä Mana, Ukachukwu Chris Manus, Herbert Robinson Marbury, Reuel Norman Marigza, Jacqueline Mariña, Antti Marjanen, Luiz C. L. Marques, Madipoane Masenya (ngwan'a Mphahlele), Caleb J. D. Maskell, Steve Mason, Thomas Massaro, Fernando Matamoros Ponce, András Máté-Tóth, Odair Pedroso Mateus, Dinis Matsolo, Fumitaka Matsuoka, John D'Arcy May, Yelena Mazour-Matusevich, Theodore Mbazumutima, John S. McClure, Christian McConnell, Lee Martin McDonald, Gary B. McGee, Thomas McGowan, Alister E. McGrath, Richard J. McGregor, John A. McGuckin, Maud Burnett McInerney, Elsie Anne McKee, Mary B. McKinley, James F. McMillan, Ernan McMullin, Kathleen E. McVey, M. Douglas Meeks, Monica Jyotsna Melanchthon, Ilie Melniciuc-Puica, Everett Mendoza, Raymond A. Mentzer, William W. Menzies, Ina Merdjanova, Franziska Metzger, Constant J. Mews, Marvin Meyer, Carol Meyers, Vasile Mihoc, Gunner Bjerg Mikkelsen, Maria Inêz de Castro Millen, Clyde Lee Miller, Bonnie J. Miller-McLemore, Alexander Mirkovic, Paul Misner, Nozomu Miyahira, R. W. L. Moberly, Gerald Moede, Aloo Osotsi Mojola, Sunanda Mongia, Rebeca Montemayor, James Moore, Roger E. Moore, Craig E. Morrison O.Carm, Jeffry H. Morrison, Keith Morrison, Wilson J. Moses, Tefetso Henry Mothibe, Mokgethi Motlhabi, Fulata Moyo, Henry Mugabe, Jesse Ndwiga Kanyua Mugambi, Peggy Mulambya-Kabonde, Robert Bruce Mullin, Pamela Mullins Reaves, Saskia Murk Jansen, Heleen L. Murre-Van den Berg, Augustine Musopole, Isaac M. T. Mwase, Philomena Mwaura, Cecilia Nahnfeldt, Anne Nasimiyu Wasike, Carmiña Navia Velasco, Thulani Ndlazi, Alexander Negrov, James B. Nelson, David G. Newcombe, Carol Newsom, Helen J. Nicholson, George W. E. Nickelsburg, Tatyana Nikolskaya, Damayanthi M. A. Niles, Bertil Nilsson, Nyambura Njoroge, Fidelis Nkomazana, Mary Beth Norton, Christian Nottmeier, Sonene Nyawo, Anthère Nzabatsinda, Edward T. Oakes, Gerald O'Collins, Daniel O'Connell, David W. Odell-Scott, Mercy Amba Oduyoye, Kathleen O'Grady, Oyeronke Olajubu, Thomas O'Loughlin, Dennis T. Olson, J. Steven O'Malley, Cephas N. Omenyo, Muriel Orevillo-Montenegro, César Augusto Ornellas Ramos, Agbonkhianmeghe E. Orobator, Kenan B. Osborne, Carolyn Osiek, Javier Otaola Montagne, Douglas F. Ottati, Anna May Say Pa, Irina Paert, Jerry G. Pankhurst, Aristotle Papanikolaou, Samuele F. Pardini, Stefano Parenti, Peter Paris, Sung Bae Park, Cristián G. Parker, Raquel Pastor, Joseph Pathrapankal, Daniel Patte, W. Brown Patterson, Clive Pearson, Keith F. Pecklers, Nancy Cardoso Pereira, David Horace Perkins, Pheme Perkins, Edward N. Peters, Rebecca Todd Peters, Bishop Yeznik Petrossian, Raymond Pfister, Peter C. Phan, Isabel Apawo Phiri, William S. F. Pickering, Derrick G. Pitard, William Elvis Plata, Zlatko Plese, John Plummer, James Newton Poling, Ronald Popivchak, Andrew Porter, Ute Possekel, James M. Powell, Enos Das Pradhan, Devadasan Premnath, Jaime Adrían Prieto Valladares, Anne Primavesi, Randall Prior, María Alicia Puente Lutteroth, Eduardo Guzmão Quadros, Albert Rabil, Laurent William Ramambason, Apolonio M. Ranche, Vololona Randriamanantena Andriamitandrina, Lawrence R. Rast, Paul L. Redditt, Adele Reinhartz, Rolf Rendtorff, Pål Repstad, James N. Rhodes, John K. Riches, Joerg Rieger, Sharon H. Ringe, Sandra Rios, Tyler Roberts, David M. Robinson, James M. Robinson, Joanne Maguire Robinson, Richard A. H. Robinson, Roy R. Robson, Jack B. Rogers, Maria Roginska, Sidney Rooy, Rev. Garnett Roper, Maria José Fontelas Rosado-Nunes, Andrew C. Ross, Stefan Rossbach, François Rossier, John D. Roth, John K. Roth, Phillip Rothwell, Richard E. Rubenstein, Rosemary Radford Ruether, Markku Ruotsila, John E. Rybolt, Risto Saarinen, John Saillant, Juan Sanchez, Wagner Lopes Sanchez, Hugo N. Santos, Gerhard Sauter, Gloria L. Schaab, Sandra M. Schneiders, Quentin J. Schultze, Fernando F. Segovia, Turid Karlsen Seim, Carsten Selch Jensen, Alan P. F. Sell, Frank C. Senn, Kent Davis Sensenig, Damían Setton, Bal Krishna Sharma, Carolyn J. Sharp, Thomas Sheehan, N. Gerald Shenk, Christian Sheppard, Charles Sherlock, Tabona Shoko, Walter B. Shurden, Marguerite Shuster, B. Mark Sietsema, Batara Sihombing, Neil Silberman, Clodomiro Siller, Samuel Silva-Gotay, Heikki Silvet, John K. Simmons, Hagith Sivan, James C. Skedros, Abraham Smith, Ashley A. Smith, Ted A. Smith, Daud Soesilo, Pia Søltoft, Choan-Seng (C. S.) Song, Kathryn Spink, Bryan Spinks, Eric O. Springsted, Nicolas Standaert, Brian Stanley, Glen H. Stassen, Karel Steenbrink, Stephen J. Stein, Andrea Sterk, Gregory E. Sterling, Columba Stewart, Jacques Stewart, Robert B. Stewart, Cynthia Stokes Brown, Ken Stone, Anne Stott, Elizabeth Stuart, Monya Stubbs, Marjorie Hewitt Suchocki, David Kwang-sun Suh, Scott W. Sunquist, Keith Suter, Douglas Sweeney, Charles H. Talbert, Shawqi N. Talia, Elsa Tamez, Joseph B. Tamney, Jonathan Y. Tan, Yak-Hwee Tan, Kathryn Tanner, Feiya Tao, Elizabeth S. Tapia, Aquiline Tarimo, Claire Taylor, Mark Lewis Taylor, Bishop Abba Samuel Wolde Tekestebirhan, Eugene TeSelle, M. Thomas Thangaraj, David R. Thomas, Andrew Thornley, Scott Thumma, Marcelo Timotheo da Costa, George E. “Tink” Tinker, Ola Tjørhom, Karen Jo Torjesen, Iain R. Torrance, Fernando Torres-Londoño, Archbishop Demetrios [Trakatellis], Marit Trelstad, Christine Trevett, Phyllis Trible, Johannes Tromp, Paul Turner, Robert G. Tuttle, Archbishop Desmond Tutu, Peter Tyler, Anders Tyrberg, Justin Ukpong, Javier Ulloa, Camillus Umoh, Kristi Upson-Saia, Martina Urban, Monica Uribe, Elochukwu Eugene Uzukwu, Richard Vaggione, Gabriel Vahanian, Paul Valliere, T. J. Van Bavel, Steven Vanderputten, Peter Van der Veer, Huub Van de Sandt, Louis Van Tongeren, Luke A. Veronis, Noel Villalba, Ramón Vinke, Tim Vivian, David Voas, Elena Volkova, Katharina von Kellenbach, Elina Vuola, Timothy Wadkins, Elaine M. Wainwright, Randi Jones Walker, Dewey D. Wallace, Jerry Walls, Michael J. Walsh, Philip Walters, Janet Walton, Jonathan L. Walton, Wang Xiaochao, Patricia A. Ward, David Harrington Watt, Herold D. Weiss, Laurence L. Welborn, Sharon D. Welch, Timothy Wengert, Traci C. West, Merold Westphal, David Wetherell, Barbara Wheeler, Carolinne White, Jean-Paul Wiest, Frans Wijsen, Terry L. Wilder, Felix Wilfred, Rebecca Wilkin, Daniel H. Williams, D. Newell Williams, Michael A. Williams, Vincent L. Wimbush, Gabriele Winkler, Anders Winroth, Lauri Emílio Wirth, James A. Wiseman, Ebba Witt-Brattström, Teofil Wojciechowski, John Wolffe, Kenman L. Wong, Wong Wai Ching, Linda Woodhead, Wendy M. Wright, Rose Wu, Keith E. Yandell, Gale A. Yee, Viktor Yelensky, Yeo Khiok-Khng, Gustav K. K. Yeung, Angela Yiu, Amos Yong, Yong Ting Jin, You Bin, Youhanna Nessim Youssef, Eliana Yunes, Robert Michael Zaller, Valarie H. Ziegler, Barbara Brown Zikmund, Joyce Ann Zimmerman, Aurora Zlotnik, Zhuo Xinping
- Edited by Daniel Patte, Vanderbilt University, Tennessee
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- The Cambridge Dictionary of Christianity
- Published online:
- 05 August 2012
- Print publication:
- 20 September 2010, pp xi-xliv
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The effects of body size and vitamin D status on bone mass of British women from South Asian and European origin: results from the Vitamin D, Food Intake, Nutrition and Exposure to Sunlight in Southern England (D-FINES) Study
- W. T. K. Lee, A. L. Darling, P. A. Lee, A. Osborn, F. Hanjra, P. Duckworth, P. Cardew, S. Patel, R. Gray, S. A. Lanham-New
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- Journal:
- Proceedings of the Nutrition Society / Volume 69 / Issue OCE1 / 2010
- Published online by Cambridge University Press:
- 17 March 2010, E45
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Statistical properties of mechanically generated surface gravity waves: a laboratory experiment in a three-dimensional wave basin
- M. ONORATO, L. CAVALERI, S. FOUQUES, O. GRAMSTAD, P. A. E. M. JANSSEN, J. MONBALIU, A. R. OSBORNE, C. PAKOZDI, M. SERIO, C. T. STANSBERG, A. TOFFOLI, K. TRULSEN
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- Journal of Fluid Mechanics / Volume 627 / 25 May 2009
- Published online by Cambridge University Press:
- 25 May 2009, pp. 235-257
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A wave basin experiment has been performed in the MARINTEK laboratories, in one of the largest existing three-dimensional wave tanks in the world. The aim of the experiment is to investigate the effects of directional energy distribution on the statistical properties of surface gravity waves. Different degrees of directionality have been considered, starting from long-crested waves up to directional distributions with a spread of ±30° at the spectral peak. Particular attention is given to the tails of the distribution function of the surface elevation, wave heights and wave crests. Comparison with a simplified model based on second-order theory is reported. The results show that for long-crested, steep and narrow-banded waves, the second-order theory underestimates the probability of occurrence of large waves. As directional effects are included, the departure from second-order theory becomes less accentuated and the surface elevation is characterized by weak deviations from Gaussian statistics.
Ricin-resistant mutants of Leishmania major which express modified lipophosphoglycan remain infective for mice
- R. Cappai, L. Morris, T. Aebischer, A. Bacic, J. M. Curtis, M. Kelleher, K. S. McLeod, S. F. Moody, A. H. Osborn, E. Handman
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- Parasitology / Volume 108 / Issue 4 / May 1994
- Published online by Cambridge University Press:
- 06 April 2009, pp. 397-405
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Glycosylation variants of the virulent Leishmania major clone VI21 were generated by mutagenesis with N-methyl-N-nitroso-N-nitroguanidine and selected using the galactose-specific lectin Ricinus communis II (RCA II). Three mutants, 4B9, 1D1 and 1C12, which failed to bind RCA II, were found to have an altered expression of lipophosphoglycan (LPG), a molecule implicated in the attachment to host macrophages and survival within the phagolysosome. There were differences in the antigenicity, molecular weight and localization of LPG from mutant parasites as compared to V121. Expression of gp63, a surface molecule also implicated in attachment to macrophages, was unaltered. All 3 mutants caused disease when injected into genetically susceptible BALB/c mice but lesions developed at a much slower rate than those caused by the virulent V121 clone. This slow rate of lesion development did not correlate with promastigotes' ability to invade macrophages in vitro. Karyotype analysis showed that there was a reduction in the size of chromosome band number 2 in all 3 mutants. The differences in LPG and chromosome band 2 were retained by mutant clones following passage through mice, suggesting that these phenotypes are stable. Although the mutant parasites were infective and caused lesions, the changed structure of the LPG appeared to influence the virulence of the parasites.
Numerical algorithms for constrained maximum likelihood estimation
- Z. F. Li, M. R. Osborne, T. Prvan
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- Journal:
- The ANZIAM Journal / Volume 45 / Issue 1 / July 2003
- Published online by Cambridge University Press:
- 17 February 2009, pp. 91-114
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This paper describes a SQP-type algorithm for solving a constrained maximum likelihood estimation problem that incorporates a number of novel features. We call it MLESOL. MLESOL maintains the use of an estimate of the Fisher information matrix to the Hessian of the negative log-likelihood but also encompasses a secant approximation S to the second-order part of the augmented Lagrangian function along with tests for when to use this information. The local quadratic model used has a form something like that of Tapia's SQP augmented scale BFGS secant method but explores the additional structure of the objective function. The step choice algorithm is based on minimising a local quadratic model subject to the linearised constraints and an elliptical trust region centred at the current approximate minimiser. This is accomplished using the Byrd and Omojokun trust region approach, together with a special module for assessing the quality of the step thus computed. The numerical performance of MLESOL is studied by means of an example involving the estimation of a mixture density.
The effect of waves on subgrid-scale stresses, dissipation and model coefficients in the coastal ocean bottom boundary layer
- W. A. M. NIMMO SMITH, J. KATZ, T. R. OSBORN
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- Journal of Fluid Mechanics / Volume 583 / 25 July 2007
- Published online by Cambridge University Press:
- 04 July 2007, pp. 133-160
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Six sets of particle image velocimetry (PIV) data from the bottom boundary layer of the coastal ocean are examined. The data represent periods of high, moderate and weak mean flow relative to the amplitude of wave-induced motion, which correspond to high, moderate and low Reynolds numbers based on the Taylor microscale (Re). The two-dimensional PIV velocity distributions enable spatial filtering to calculate some of the subgrid-scale (SGS) stresses, from which we can estimate the SGS dissipation, and evaluate the performance of typically used SGS stress models. The previously reported mismatch between the SGS and viscous dissipation at moderate and low Reynolds numbers appears to be related to the sparsity of large vortical structures that dominate energy fluxes.
Conditional sampling of SGS stresses and dissipation based on wave phase using Hilbert transforms demonstrate persistent and repeatable direct effects of large-scale but weak straining by the waves on the SGS energy flux at small scales. The SGS energy flux is phase-dependent, peaking when the streamwise-wave-induced velocity is accelerating, and lower when this velocity is decelerating. Combined with strain rate generated by the mean flow, the streamwise wave strain causes negative energy flux (backscatter), whereas the vertical wave strain causes a positive flux. The phase-dependent variations and differences between horizontal and vertical contributions to the cascading process extend to strains that are substantially higher than the wave-induced motion. These trends may explain the measured difference between spatial energy spectra of streamwise velocity fluctuations and spectra of the wall-normal component, i.e. the formation of spectral bumps in the spectra of the streamwise component at the wavenumbers for the transition between inertial and dissipation scales.
All the model coefficients of typical SGS stress models measured here are phase dependent and show similar trends. Thus, the variations of measured SGS dissipation with phase are larger than those predicted by the model variables. In addition, the measured coefficients of the static Smagorinsky SGS stress model decrease with decreasing turbulence levels, and increase with filter size. The dynamic model provides higher correlation coefficients than the Smagorinsky model, but the substantial fluctuations in their values indicate that ensemble averaging is required. The ‘global’ dynamic model coefficients indicate that the use of a scale-dependent dynamic model may be appropriate. The structure function model yields poor correlation coefficients and is found to be over-dissipative under all but the highest turbulence levels. The nonlinear model has higher correlations with measured stresses, as expected, but it also does not reproduce the trends with wave phase.
Local isotropy and the decay of turbulence in a stratified fluid
- A. E. Gargett, T. R. Osborn, P. W. Nasmyth
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- Journal:
- Journal of Fluid Mechanics / Volume 144 / July 1984
- Published online by Cambridge University Press:
- 20 April 2006, pp. 231-280
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The validity of the assumption of local isotropy is investigated using measurements of three orthogonal components of the turbulent velocity fields associated with initially high-Reynolds-number geophysical turbulence. The turbulent fields, generated by various large-scale internal motions caused by tidal flows over an estuarine sill, decay under the influence of stable mean density gradients. With measurements from sensors mounted on a submersible, we examine the evolution of spectral shapes and of ratios of cross-stream to streamwise components, as well as the degree of high-wavenumber universality, for the observational range of the parameter I≡ ks/kb = lb/ls. This ratio is a measure of separation between the Kolmogoroff wavenumber ks≡ (ε/ν3)¼ ≡ 2π/ls typical of scales by which turbulent kinetic energy has been dissipated (at rate ε), and the buoyancy wavenumber kb ≡ (N3/ε)½ ≡ 2π/lb typical of scales at which the ambient stratification parameter N ≡ (−gρz/ρ0)½ becomes important. For values of I larger than ∼ 3000, inertial subranges are observed in all spectra, and the spectral ratio ϕ22/ϕ11 of cross-stream to streamwise spectral densities reaches the isotropic value of 4/3 for about a decade in wavenumber. As ks/kb decreases, inertial subranges vanish, but spectra of the cross-stream and streamwise components continue to satisfy isotropic relationships at dissipation wavenumbers. We provide a criterion for when ε may safely be estimated from a single measured component of the dissipation tensor, and also explore questions of appropriate low-wavenumber normalization for buoyancy-modified turbulence.
Multiwavelength observations of eclipsing polars
- A. Schwope, V. Hambaryan, A. Staude, R. Schwarz, G. Kanbach, H. Steinle, F. Schrey, T. Marsh, V. Dhillon, J. Osborne, P. Wheatley, S. Potter
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- Journal:
- International Astronomical Union Colloquium / Volume 190 / 2004
- Published online by Cambridge University Press:
- 12 April 2016, pp. 92-105
- Print publication:
- 2004
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Multiwavelength observations of polars are essential for developing the big picture of these systems, particularly to gain understanding of the relevant accretion-induced heating and cooling processes. Eclipsing polars are prime targets for such studies since different radiation processes can be disentangled by observations with high-time resolution. We present a preliminary combined analysis of space-based observations (XMM-Newton, ROSAT, HST) with ground-based high-speed photometry (MCCP, OPTIMA, ULTRACAM) of DP Leo, HU Aqr and UZ For. We determine the location and extent of different emission components and find secular and short-term changes in the accretion geometries. We find displaced optical and X-ray emission regions in DP Leo and HU Aqr as well as mini-bursts and accretion arcs of variable size in HU Aqr. We report marked changes in the X-ray eclipse length of UZ For between high and low states.
The importance of high temperature electron-phonon coupling to the thermodynamic properties of Ce0.9Th0.1 and other f-electron bonded metals
- M. E. Manley, R. J. McQueeney, B. Fultz, T. Swan-Wood, O. Delaire, E. A. Goremychkin, J. C. Cooley, W. L. Hults, J. C. Lashley, R. Osborn, J. L. Smith
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- Journal:
- MRS Online Proceedings Library Archive / Volume 802 / 2003
- Published online by Cambridge University Press:
- 01 February 2011, DD2.3
- Print publication:
- 2003
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Recent results from inelastic neutron scattering studies on Ce0.9Th0.1 are used to demonstrate the importance of electron-phonon coupling to the physical properties of f-electron bonded metals. In the case of Ce0.9Th0.1, the phonon density of states (DOS) of α-phase shows a significant softening when heated but shows no change across the α-γ transition despite the 11% volume change. This is supported by analysis of the magnetic spectra showing that most of the transition entropy can be accounted for with the crystal field and spin fluctuations. The precursor phonon softening, the lack of any phonon change across the transition, the magnetic spectra, and the volume transition itself can all be explained in terms of the atomic displacement sensitivity of the hybridization of the local f-electrons with conduction electrons. The electron-phonon coupling resulting from these displacement-sensitive electronic states appears to be essential to understanding cerium. Some of the behavior characteristic of these states, a large volume changes and precursor phonon softening, occurs in many other f-electron bonded metals suggesting that the phenomena is not unique to cerium.
The European Sero-Epidemiology Network: standardizing the enzyme immunoassay results for measles, mumps and rubella
- N. ANDREWS, R. G. PEBODY, G. BERBERS, C. BLONDEAU, P. CROVARI, I. DAVIDKIN, P. FARRINGTON, F. FIEVET-GROYNE, G. GABUTTI, E. GERIKE, C. GIORDANO, L. HESKETH, T. MARZEC, P. MORGAN-CAPNER, K. OSBORNE, A. M. PLEISNER, M. RAUX, A. TISCHER, U. RUDEN, M. VALLE, E. MILLER
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- Journal:
- Epidemiology & Infection / Volume 125 / Issue 1 / August 2000
- Published online by Cambridge University Press:
- 06 November 2000, pp. 127-143
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The ESEN (European Sero-Epidemiology Network) project was established to harmonize the seroepidemiology of five vaccine preventable infections including measles, mumps and rubella in eight European countries. This involved achieving comparability both in the assay results from testing in different centres and also sampling methodology. Standardization of enzyme immunoassay results was achieved through the development of common panels of sera by designated reference centres. The panels were tested at the reference laboratory and then distributed to each participating laboratory for testing using their routine methods. Standardization equations were calculated by regressing the quantitative results against those of the reference laboratory. Our study found large differences in unitage between participants, despite all using an EIA method standardized against an international or local standard. Moreover, our methodology adjusted for this difference. These standardization equations will be used to convert the results of main serosurvey testing into the reference country unitage to ensure inter-country comparability.
Selective Screening of Hospitalized Patients for the Presence of Asymptomatic Hepatitis B Virus Carriage: Predictability Based on Census Tract Data
- Larry M. Baddour, Billy R. Jennings, Pamela T. Osborne, Robert C. Rendtorff, Marge C. Moffatt, Ginger M. Luther, Jamie L. Holcomb
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- Journal:
- Infection Control / Volume 7 / Issue 11 / November 1986
- Published online by Cambridge University Press:
- 02 January 2015, pp. 546-549
- Print publication:
- November 1986
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Review of all hepatitis B surface antigen-positive patients reported to the county health department over the past 3 years showed that 60% of patients had been diagnosed at our hospital, which serves an inner city, predominantly black, indigent population. Sera from 524 adult patients admitted to the hospital were prospectively collected and tested for hepatitis B surface antigen, eight (1.5%) of which were antigen-positive. Census tract data allowed us to perform selective screening of sera from 95 other patients who were subsequently hospitalized and deemed “high risk” for hepatitis B infection. Nine of 95 (9.5%) selectively screened samples were positive for hepatitis B surface antigen, which represented a significantly higher rate of antigen carriage (P<0.0001) in hospitalized patients from “high risk” areas than that found in the general population screen. The methodology presented herein may be useful in providing a means of identifying hepatitis B surface antigen-positive patients from adult, urban, indigent care populations.
A Comparison of the Antidepressant Action of Citalopram and Amitriptyline
- D. M. Shaw, D. R. Thomas, M. H. Briscoe, R. Crimmins, B. Harris, J. Lovett, M. Raj, A. T. Lloyd, C. Osborne, G. Hughes, W. Waheed, J. Davies, A. B. Rolfe, E. Satheesan, A. Snape, V. M. Evans, N. Patel, M. A. Bari
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- Journal:
- The British Journal of Psychiatry / Volume 149 / Issue 4 / October 1986
- Published online by Cambridge University Press:
- 29 January 2018, pp. 515-517
- Print publication:
- October 1986
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The response of patients with major depressive illness to citalopram of amitriptyline was compared in a double-blind multi-centre trial. No differences in efficacy were observed, but citalopram had less hypnotic effect and a remarkably lower profile of side-effects.
The Clarification and Assessment of a Method of Psychotherapy
- D. P. Goldberg, R. F. Hobson, G. P. Maguire, F. Margison, T. O'Dowd, M. Osborn, S. Moss
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- Journal:
- The British Journal of Psychiatry / Volume 144 / Issue 6 / June 1984
- Published online by Cambridge University Press:
- 29 January 2018, pp. 567-575
- Print publication:
- June 1984
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The ‘conversational model’ of psychotherapy was investigated with a view to discovering which behaviours distinguish psychotherapists trained in this method from others, of equal clinical experience. A rating scheme designed to capture the theoretical aspects of the model, and 30 predictions were made concerning behaviours which were expected to distinguish the psychotherapists. Five psychotherapists were matched to five psychiatrists who had not been trained in this method; each doctor took on four patients for therapy, and each patient was seen on five occasions. All interviews were recorded, and excerpts from the recordings rated. Only ten of the 30 predictions were upheld. In ten further predictions, the psychotherapists displayed the appropriate behaviours, but the behaviours were not peculiar to the model, since eclectic psychiatrists also displayed them. Six model behaviours were not practised frequently by the psychotherapists, and four ‘non-model’ behaviours were equally common in either group. The research formed the basis for the preparation of materials to teach psychotherapeutic skills in a more efficient way.