Skip to main content Accessibility help
×
Hostname: page-component-76fb5796d-45l2p Total loading time: 0 Render date: 2024-04-29T22:23:36.368Z Has data issue: false hasContentIssue false

VIII.61 - Goiter

from Part VIII - Major Human Diseases Past and Present

Published online by Cambridge University Press:  28 March 2008

Kenneth F. Kiple
Affiliation:
Bowling Green State University, Ohio
Get access

Summary

Quis tumidum guttur miratur in Alpibus?

Juvenal, Satire 13, c. A.D. 127

Goiter is an ancient disease that has always been more common in some places than in others. Chinese writings show that goiter was known at least by the third century B.C. (Lee 1941) and possibly earlier (Needham et al. 1970). When Juvenal (Decimus Junius Juvenalis), the Roman satirist, wrote, about A.D. 127, “Who is amazed at a swollen neck in the Alps?” he knew that goiter was so much more common there than elsewhere that it should be no surprise.

Terminology

The word “goiter” (or goitre in Europe) derives from the Latin gutter, but the meaning has shifted from “throat” or “neck” to mean specifically an enlarged thyroid gland. An ancient Greek synonym was bronchocele, a term actually used to describe any enlargement in the neck, although it meant literally a swelling or an outpouching of the trachea. Over time this term also came to mean an enlarged thyroid (e.g., the English “bronchocele” of the eighteenth and nineteenth centuries). Modern synonyms are the Spanish bocio (from Latin, botium), the Italian gozzo, and the German Kropf. The ancient Latin word struma was probably originally used to describe inflamed lymph nodes in the neck, most likely tuberculous, but was later used to denote the normal thyroid gland, and is still so used although it is almost obsolete.

Confusion over names is understandable, as the thyroid gland itself was unknown until the sixteenth century. Leonardo da Vinci may have drawn the thyroid about the year 1500, but the drawing was not published until much later. Andreas Vesalius did note “laryngeal glands” in 1543, but not in humans.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Alibert, J.–L. 1835. Monographic des dermatoses ou précis théorique et pratique des maladies de la peau, 2d edition. Paris.Google Scholar
Baillarger, J. G. F. 1873. Enquête sur le goitre et le crétinisme. Reviewed in: Gazette Hebdomadaire de Médicine et de Chirurgie, 2d ser., 10.Google Scholar
Baumann, E. 1895. Ueber das normale Vorkommen von Jod im Thierkörper. Hoppe-Seyler’s Zeitschrift für Physiologische Chemie 21.Google Scholar
Bruns, P. 1894. Ueber die Kropfbehandlung mit Schildrüsenfütterung. Deutsche Medizinische Wochenschrift 41.Google Scholar
Chatin, A. 1850a. Existence de l’iode dans les plantes d’eau douce: Consequences de ce fait pour la géognosie, la physiologie végétale, la thérapeutique et peut-être pour l’industrie. Comtes Rendus Hebdomadaires de I’Acadimie des Sciences 30.Google Scholar
Chatin, A. 1850b. Recherches sur l’iode des eaux douce (suite): De la présence de ce corps dans les plantes et les animaux terrestres. Comtes Rendus Hebdomadaires de I’Académie des Sciences 31.Google Scholar
Cranefield, P. F. 1962. The discovery of cretinism. Bulletin of the History of Medicine 36.Google ScholarPubMed
DeGroot, L. J., et al. 1983. Retrospective and prospective study of radiation-induced thyroid disease. American Journal of Medicine 74.CrossRefGoogle ScholarPubMed
Delange, F. M., and Ermans, A. M.. 1976. Endemic goiter and cretinism: Naturally occurring goitrogens. Pharmacology and therapy [C] 1.Google Scholar
Dumas, ( J.-B., et al. 1851. Rapport sur les recherches de M. le Dr. Grange, relatives aux causes du crélinisme et du goître, et aux moyens d’en préserver les populations. Comtes Rendus Hebdomadaires de I’Académie des Sciences 32.Google Scholar
Follis, R. H. Jr. 1960. Cellular pathology and the development of the deficiency disease concept. Bulletin of the History of Medicine 34.Google ScholarPubMed
Gaitan, E., et al. 1983. In vitro measurement of antithyroid compounds and environmental goitrogens. Journal of Clinical Endocrinology and Metabolism 56.CrossRefGoogle ScholarPubMed
Hamilton, T. E., et al. 1987. Thyroid neoplasia in Marshall Islanders exposed to nuclear fallout. Journal of the American Medical Association 258.Google ScholarPubMed
Harington, C. R. 1933. The thyroid gland: Its chemistry and physiology. London. [A historical chapter on goiter and cretinism].Google Scholar
Hirsch, A. 1885. Handbook of geographical and historical pathology, Vol. II. Chronic infective, toxic, parasitic, septic and constitutional diseases, trans. Creighton, C., from the 2nd German edition. London.Google Scholar
Inglis, J. 1838. Treatise on English bronchocele with a few remarks on the use of iodine and its compounds. London.Google Scholar
Kendall, E. C. 1915. The isolation in crystalline form of the compound which occurs in the thyroid: Its chemical nature and physiologic activity. Journal of the American Medical Association 64.Google Scholar
Lee, T. 1941. A brief history of the endocrine disorders in China. Chinese Medical Journal 59.Google Scholar
Lugol, J.-G.-A. 1829. Mémoire sur l’emploi de l’iode dans les maladies scrophuleuses. Paris.Google Scholar
Marine, D., and Lenhart, C. H.. 1910. On the occurrence of goitre (active thyroid hyperplasia) in fish. Bulletin of Johns Hopkins Hospital 21.Google Scholar
Marine, D., and Kimball, O. P.. 1920. Prevention of simple goiter in man. Archives of Internal Medicine 25.CrossRefGoogle Scholar
Matovinovic, J. 1983. Endemic goiter and cretinism at the dawn of the third millennium. Annual Review of Nutrition 3.CrossRefGoogle ScholarPubMed
Mazzaferri, E. L., and Young, R. L.. 1981. Papillary thyroid carcinoma: A 10-year follow-up report of the impact of therapy in 576 patients. American Journal of Medicine 70.CrossRefGoogle ScholarPubMed
McClendon, J. F. 1939. Iodine and the incidence of goiter. Minneapolis.Google Scholar
McClendon, J.F., and Williams, A.. 1923. Experimental goitre and iodine in natural waters in relation to distribution of goitre. Proceedings of the Society for Experimental Biology and Medicine 20.Google Scholar
Merke, F. 1984. History and iconography of endemic goitre and cretinism. Berne-Hingham. [An excellent guide to older works].Google Scholar
Morimoto, T., et al. 1987. Serum TSH, thyroglobulin, and thyroidal disorders in atomic bomb survivors exposed in youth: 30-year follow-up study. Journal of Nuclear Medicine 28.Google ScholarPubMed
Murray, G. R. 1891. Note on the treatment of myxoedema by hypodermic injections of an extract of the thyroid gland of a sheep. British Medical Journal 2.CrossRefGoogle ScholarPubMed
Needham, J., et al. 1970. Proto-endocrinology in medieval China. In Clerks and craftsmen in China and the West. Cambridge.Google Scholar
Ord, W. M. (chairman). 1888. Report of a committee of the Clinical Society of London nominated December 14, 1883, to investigate the subject of myxoedema. Transactions of the Clinical Society of London 21 (Supplement):.Google Scholar
Osler, W. 1892. The principles and practice of medicine, 1st edition. New York.Google Scholar
Osler, W. 1896. The principles and practice of medicine, 2d edition. New York.Google Scholar
Pepper, W., ed. 1894. A textbook of the theory and practice of medicine by American teachers, Vol. 2. Philadelphia.Google Scholar
Reinhold, G. 1894. Ueber Schilddrüsen Therapie bei kropfleidenden Geisteskranken. Münchener medizinische Wochenschrift 41.Google Scholar
Rolleston, H. D. 1936. The endocrine organs in health and disease with an historical review. London. [See especially].Google Scholar
Scriba, P. C., et al. 1985. Goitre and iodine deficiency in Europe. Lancet 1.Google Scholar
Stanbury, J. B., and Hetzel, B. S., eds., 1980. Endemic goiter and endemic cretinism: Iodine nutrition in health and disease. New York. [A modern detailed text].Google Scholar
Thénard, L. J., et al. 1852. Rapport sur les travaux de M. Chatin, relatifs à la recherche de l’iode, et sur différentes notes ou mémoires présentés sur le même sujet, par MM. Marchand, Nièpce, Meyrac. Comtes Rendus Hebdomadaires de I’Académie des Sciences 35.Google Scholar
Thorpe, T. E. 1902. Essays on historical chemistry. London.Google Scholar
Wood, H. C Jr. 1881. A treatise on therapeutics, 3d edition. Philadelphia.Google Scholar
,World Health Organization (WHO). 1960. Endemic goitre. Geneva. [Strong on epidemiology with good maps and a short historical chapter].

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

  • Goiter
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.123
Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

  • Goiter
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.123
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Goiter
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.123
Available formats
×