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VIII.1 - Acquired Immune Deficiency Syndrome (AIDS)

from Part VIII - Major Human Diseases Past and Present

Published online by Cambridge University Press:  28 March 2008

Kenneth F. Kiple
Affiliation:
Bowling Green State University, Ohio
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Summary

Acquired immune deficiency syndrome (AIDS), first identified in 1981, is an infectious disease characterized by a failure of the body’s immunologic system. As a result, affected individuals become increasingly vulnerable to many normally harmless microorganisms, eventually leading to severe morbidity and high mortality. The infection, spread sexually and through blood, has a high fatality rate, approaching 100 percent. Caused by a human retrovirus known as HIV-1, AIDS can now be found throughout the world – in both Western industrialized countries and also the developing nations of Africa and Latin America.

Although precise epidemiological data remain unknown, public health officials throughout the world have focused attention on this pandemic and its potentially catastrophic impact on health, resources, and social structure. Treatments for the disease have been developed, but there is currently no cure or vaccine.

Etiology and Epidemiology

Beginning in the late 1970s, physicians in New York and California reported the increasing occurrence of a rare type of cancer, Kaposi’s sarcoma, and a variety of infections including pneumocystis pneumonia among previously healthy young homosexual men. Because of the unusual character of these diseases, which are typically associated with a failure of the immune system, epidemiologists began to search for characteristics that might link these cases. AIDS was first formally described in 1981, although it now appears that the virus that causes the disease must have been silently spreading in a number of populations during the previous decade. Early epidemiological studies suggested that homosexual men, recipients of blood transfusions and blood products (especially hemophiliacs), and intravenous drug users were at greatest risk for the disease.

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Publisher: Cambridge University Press
Print publication year: 1993

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References

Anderson, R. M., May, R. M., and McLean, A. R.. 1988. Possible demographic consequences of AIDS in developing countries. Nature 332.CrossRefGoogle ScholarPubMed
Bayer, Ronald. 1989. AIDS, privacy, and responsibility. Daedalus 118.Google ScholarPubMed
Bloom, David E., and Carliner, Geoffrey. 1988. The economic impact of AIDS in the United States. Science 239.CrossRefGoogle ScholarPubMed
Christakis, Nicholas A. 1989. Responding to a pandemic: International interests in AIDS control. Daedalus 118.Google Scholar
Cotton, Deborah. 1988. The impact of AIDS on the medical care system. Journal of the American Medical Association 260.Google ScholarPubMed
Curran, James W., et al. 1988. Epidemiology HIV infection and AIDS in the United States. Science 239.CrossRefGoogle ScholarPubMed
Fauci, Anthony S. 1983. The acquired immune deficiency syndrome: The ever broadening clinical spectrum. Journal of the American Medical Association 249.Google ScholarPubMed
Fauci, Anthony S. 1988. The human immunodeficiency virus: Infectivity and mechanisms of pathogenesis. Science 239.CrossRefGoogle ScholarPubMed
Fineberg, Harvey V. 1988. Education to prevent AIDS: Prospects and obstacles. Science 239.CrossRefGoogle ScholarPubMed
Fineberg, Harvey V. 1988. The social dimensions of AIDS. Scientific American 259.CrossRefGoogle Scholar
Fox, Daniel M. 1986. AIDS and the American health policy: The history and prospects of a crisis of authority. Milbank Quarterly 64.CrossRefGoogle ScholarPubMed
Fox, Daniel M., Day, Patricia, and Klein, Rudolf. 1989. The power of professionalism: Policies for AIDS in Britain, Sweden, and the United States. Daedalus 118.Google ScholarPubMed
Friedland, G. H., and Klein, R. S.. 1987. Transmission of the human immunodeficiency virus. New England Journal of Medicine 317.CrossRefGoogle ScholarPubMed
Friedland, Gerald H. 1989. Clinical care in the AIDS epidemic. Daedalus 118.Google ScholarPubMed
Friedman, Samuel, et al. 1987. The AIDS epidemic among blacks and Hispanics. Milbank Quarterly 65 (Suppl. 2):.CrossRefGoogle ScholarPubMed
Gallo, Robert, and Montagnier, Luc. 1988. AIDS in 1989. Scientific American 259.Google Scholar
Gostin, Larry. 1986. The future of communicable disease control: Toward a new concept in public health law. Milbank Quarterly 64.CrossRefGoogle Scholar
Hamburg, Margaret A., and Fauci, Anthony S.. 1989. AIDS: The challenge to biomedical research. Daedalus 118.Google Scholar
Haseltine, William A. 1989. Prospects for the medical control of the AIDS epidemic. Daedalus 118.Google Scholar
Heyward, William L., and Curran, James W.. 1988. The epidemiology of AIDS in the U.S. Scientific American 259.CrossRefGoogle ScholarPubMed
,Institute of Medicine. National Academy of Sciences. 1988. Confronting AIDS. Washington, D.C..
Keniston, Kenneth. 1989. Introduction to the issue. Daedalus 118.Google Scholar
Macklin, R., and Friedland, G. H.. 1986. AIDS research: The ethics of clinical trials. Law, Medicine, and Health-Care 14.CrossRefGoogle ScholarPubMed
Mann, Jonathan M., et al. 1988. The international epidemiology of AIDS. Scientific American 259.CrossRefGoogle Scholar
May, Robert M., Anderson, Roy M., and Blower, Sally M.. 1989. The epidemiology and transmission dynamics of HIV AIDS. Daedalus 118.Google Scholar
Nelkin, Dorothy, and Hilgartner, Stephen. 1986. Disputed dimensions of risk: A public school controversy over AIDS. Milbank Quarterly 64.CrossRefGoogle ScholarPubMed
Nicholas, Eve K. 1989. Mobilizing against AIDS. Cambridge, Mass..Google Scholar
Osborn, June E. 1988. AIDS: Politics and science. New England Journal of Medicine 318.CrossRefGoogle Scholar
Osborn, June E. 1989. Public health and the politics of AIDS prevention. Daedalus 118.Google ScholarPubMed
,Panos Institute. 1988. AIDS and the Third World: Update. Washington, D.C..
Piot, Peter, et al. 1988. AIDS: An international perspective. Science 239.CrossRefGoogle Scholar
,Presidential Commission on the Human Immunodeficiency Virus Epidemic. Report. 1988. Washington, D.C..
Ron, Aran, and Rogers, David E.. 1989. AIDS in the United States: Patient care and politics. Daedalus 118.Google ScholarPubMed
Rosenberg, Charles E. 1989. What is an epidemic?Daedalus 118.Google ScholarPubMed
Shilts, Randy. 1987. And the band played on. New York.Google Scholar
,U.S. Office of Technology Assessment. 1985. Review of the public health services response to AIDS: A technical memorandum. Washington, D.C.
Winkenwerder, William, Kessler, Austin R., and Stolec, Rhonda M.. 1989. Federal spending for illness caused by the human immunodeficiency virus. New England Journal of Medicine 320.CrossRefGoogle ScholarPubMed
Zalduondo, Barbara O., Msamanga, Gernard Iddi, and Chen, Lincoln C.. 1989. AIDS in Africa: Diversity in the global pandemic. Daedalus 118.Google Scholar

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