Skip to main content Accessibility help
×
Hostname: page-component-76fb5796d-45l2p Total loading time: 0 Render date: 2024-04-25T08:54:09.669Z Has data issue: false hasContentIssue false

VIII.110 - Poliomyelitis

from Part VIII - Major Human Diseases Past and Present

Published online by Cambridge University Press:  28 March 2008

Kenneth F. Kiple
Affiliation:
Bowling Green State University, Ohio
Get access

Summary

Poliomyelitis is an acute disease caused by inflammation and destruction of motor neurons after infection by a poliovirus. Sensory functions are not affected. Although frequently asymptomatic, the infection may cause fever and a number of other general symptoms, described as abortive polio or minor illness. Occasionally, however, these prodromal symptoms are followed a few days later by infection of the central nervous system (CNS) and fever, with meningitis, or paresis (weakness) or paralysis of one or more muscles. Many patients recover use of the muscle or some muscles affected in the following months, although some have permanent paralysis or paresis. When the muscles of respiration are affected, death may follow.

Other enteroviruses of the ECHO (Enteric Cytopathic Human Orphan virus) and Coxsackie groups may also cause meningitis and paresis, or temporary paralysis. In the past, cases of abortive polio and those with paralysis who later recovered were often included in statistics as polio cases. Today, only cases with paralysis or paresis after 3 months are recorded as paralytic polio.

Poliomyelitis was known by several names until the 1870s, when it became known as acute anterior poliomyelitis. Among them was Heine–Medin disease (after two early researchers, Jacob von Heine and Karl Oscar Medin) and infantile paralysis because it affected mainly young children. As more adults and older children were affected, poliomyelitis – inflammation of the gray marrow – became the name of choice and is often shortened to polio.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bodian, David. 1976. Poliomyelitis and the sources of useful knowledge. Johns Hopkins Medical Journal 138.Google ScholarPubMed
Enders, John Franklin. 1949. Cultivation of the Lansing strain of poliomyelitis virus in cultures of various human embryonic tissues. Science 109.CrossRefGoogle ScholarPubMed
Flexner, Simon, and Lewis, Paul A.. 1910. Experimental poliomyelitis in monkeys: Active immunization and passive serum protection. Journal of the American Medical Association 54.Google Scholar
Hedley, O. F. 1940. Public Health Reports 55.Google Scholar
Koprowski, Hilary, et al. 1952. Immune responses in human volunteers upon oral administration of a rodentadapted strain of poliomyelitis virus. American Journal of Hygiene 55.Google ScholarPubMed
Lambert, A. 1920. Acute rheumatic fever. Journal of the American Medical Association 74.CrossRefGoogle Scholar
Paul, John R. 1971. A history of poliomyelitis. New Haven.Google Scholar
Sabin, Albert B. 1955. Characteristics and genetic potentialities of experimentally produced and naturally occurring variants of poliomyelitis virus. Annals of the New York Academy of Sciences 61.CrossRefGoogle ScholarPubMed
Sabin, Albert B., and Olitsky, Peter K.. 1936. Cultivation of poliomyelitis virus in vitro in human embryonic nervous tissue. Proceedings of the Society for Experimental Biology and Medicine 34.Google Scholar
Salk, Jonas E., et al. 1953. Studies in human subjects on active immunization against poliomyelitis. I. A preliminary report of experiments in progress. Journal of the American Medical Association 151.Google ScholarPubMed
Underwood, Michael. 1789. Treatise on the diseases of children. London.Google Scholar
Wickman, Ivan. 1913. Acute poliomyelitis. Nervous and mental diseases monograph series No. 16. New York.Google Scholar
,World Health Organization. 1955. Poliomyelitis. Monograph series No. 26. Geneva.
Wyatt, Harold V. 1973a. Hypogammaglobulinemia and poliomyelitis. Journal of Infectious Diseases 128.CrossRefGoogle Scholar
Wyatt, Harold V. 1973b. Is polio a model for consumer research? Nature 241.CrossRefGoogle Scholar
Wyatt, Harold V. 1975a. Is poliomyelitis a genetically-determined disease? I. A genetic model. Medical Hypotheses 1.Google Scholar
Wyatt, Harold V. 1975b. Is poliomyelitis a genetically-determined disease? II. A critical examination of the epidemiological data. Medical Hypotheses 1.Google Scholar
Wyatt, Harold V. 1975c. Risk of live poliovirus in immunodeficient children. Journal of Pediatrics 87.CrossRefGoogle Scholar
Wyatt, Harold V. 1976a. Is poliomyelitis an auto-allergic disease triggered by virus?Medical Hypotheses 2.CrossRefGoogle Scholar
Wyatt, Harold V. 1976b. Provocation poliomyelitis and entry of poliovirus to the CNS. Medical Hypotheses 2.CrossRefGoogle Scholar
Wyatt, Harold V. 1978a. Abortive poliomyelitis or minor illness as a clue to genetic susceptibility. Medical Microbiology and Immunology 166.CrossRefGoogle Scholar
Wyatt, Harold V. 1978b. Polio immunization: Benefits and risks. Journal of Family Practice 7.Google Scholar
Wyatt, Harold V. 1979. Poliomyelitis in the fetus and the newborn. A comment on the new understanding of the pathogenesis. Clinical Pediatrics 18.CrossRefGoogle ScholarPubMed
Wyatt, Harold V. 1981. Provocation poliomyelitis: Neglected clinical observations from 1914 to 1950. Bulletin of the History of Medicine 55.Google ScholarPubMed
Wyatt, Harold V. 1984. The popularity of injections in the Third World: Origins and consequences. Social Science and Medicine 19.CrossRefGoogle ScholarPubMed
Wyatt, Harold V. 1985. Provocation of poliomyelitis by multiple injections. Transactions of the Royal Society for Tropical Medicine and Hygiene 79.CrossRefGoogle ScholarPubMed
Wyatt, Harold V. 1989. Poliomyelitis in developing countries: Lower limb paralysis and injections. Transactions of the Royal Society for Tropical Medicine and Hygiene 83.CrossRefGoogle ScholarPubMed
Wyatt, Harold V. 1990. Incubation of poliomyelitis as calculated from the time of entry into the central nervous system via the peripheral nerve pathways. Reviews of Infectious Diseases 12.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

  • Poliomyelitis
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.172
Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

  • Poliomyelitis
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.172
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Poliomyelitis
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.172
Available formats
×