from Part VIII - Major Human Diseases Past and Present
Published online by Cambridge University Press: 28 March 2008
Measles (rubeola; hard measles; red measles; 9-day measles; morbilli) is a common, acute, viral infectious disease, principally of children, with worldwide distribution, that is clinically characterized by fever and a typical red, blotchy rash combined with cough, coryza, or conjunctivitis. It is a vaccine-preventable disease, and its vaccine is one of the vaccines included in the Expanded Programme on Immunization (EPI) of the World Health Organization (WHO). The disease is known by many local names throughout the world.
Etiology and Epidemiology
Measles is caused by a virus, which is in the genus Morbillivirus of the family Paramyxoviridae. Although the virus does not survive drying on a surface, it can survive drying in microdroplets in the air.
Measles is one of the most highly communicable diseases, transmitted by contact of susceptible individuals with the nose and throat secretions of infected persons, primarily by droplet spread. Infection also occurs by direct contact, and by indirect contact through freshly soiled articles and airborne transmission. There is no reservoir for measles other than human beings, which means that a continuous chain of susceptible contacts is necessary to sustain transmission. The period of communicability is from slightly before the beginning of the prodromal phase of the disease to 4 days after the start of the rash. There is no carrier state. Measles has an incubation period from time of exposure to onset of fever of about 10 days with a range from 8 to 13 days. The incubation period from time of exposure to rash onset is about 14 days.
In populated areas with no or low vaccination coverage, measles is primarily an endemic disease of children, with epidemics occurring every 2 to 5 years. In such areas, the greatest incidence is in children under 2 years of age. Epidemic measles has a winter-spring seasonality in temperate climates and a less marked hot-dry seasonality in equatorial regions.
To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Find out more about the Kindle Personal Document Service.
To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.
To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.