from Part VIII - Major Human Diseases Past and Present
Published online by Cambridge University Press: 28 March 2008
In current nosology, diseases are categorized as degenerative, malignant, genetic, endocrine, and so on. For purposes of the history of diseases we must add a category that we might term ephemeral. This requires a bit of literary license, because many conditions that fall in the class of ephemeral diseases had a longer existence than that word usually implies. Ephemeral diseases comprise a large number of entities that carried working diagnostic names for earlier physicians (see, e.g., typhomalarial fever), but that are no longer recognized, at least by their previous names (Straus 1970; Hudson 1977a; Jarcho 1980).
Clinical Manifestations
A historical example of a disease that died only to leave behind a host of sprightly ghosts is the “green sickness” or chlorosis. Although noted in two Hippocratic treatises, Prorrhetic and The Diseases of Girls, the condition received its now classic description by Johann Lange in 1554 (Hippocrates 1853, 1861). He called the condition morbus virgineus. His description contains many of the elements found in the Hippocratic texts, as does the account by Ambroise Pare in 1561. Also reflecting the Hippocratic corpus is the work of Jean Varandal who is credited with first using the word “chlorosis” in 1615 (Starobinski 1981). For Varandal, chlorosis was a class of syndromes.
Reflecting a different approach, Thomas Sydenham’s description in 1683 embodied many of the clinical features relied upon at least two centuries later:
The face and body lose colour, the face also swells; so do the eyelids and ankles. The body feels heavy; there is tension and lassitude in the legs and feet, dyspnoea, palpitation of the heart, headache, febrile pulse, somnolence, pica, and suppression of the menses.
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