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To establish the prevalence of double burden of malnutrition (DBM) and triple burden of malnutrition (TBM) among mother–child pairs in Malawi and explore their geographical distribution and associated multilevel factors.
Design:
Cross-sectional study using secondary data from the 2015–2016 Malawi Demographic and Health Survey using a mixed effects binomial model to identify multilevel factors associated with DBM and TBM. Georeferenced covariates were used to map the predicted prevalence of DBM and TBM.
Setting:
All twenty-eight districts in Malawi.
Participants:
Mother–child pairs with mothers aged 15–49 years and children aged below 60 months (n 4618 pairs) for DBM and between 6 and 59 months (n 4209 pairs) for TBM.
Results:
Approximately 5·5 % (95% confidence interval (CI): 4·7 %, 6·4 %) of mother–child pairs had DBM, and 3·1 % (95 % CI: 2·5 %, 4·0 %) had TBM. The subnational-level prevalence of DBM and TBM was highest in cities. The adjusted odds of DBM were threefold higher (adjusted Odds Ratio, AOR: 2·8, 95 % CI: 1·1, 7·3) with a higher proportion of wealthy households in a community. The adjusted odds of TBM were 60 % lower (AOR: 0·4; 95 % CI: 0·2, 0·8) among pairs where the women had some education compared with women with no education.
Conclusions:
Although the prevalence of DBM and TBM is currently low in Malawi, it is more prevalent in pairs with women with no education and in relatively wealthier communities. Targeted interventions should address both maternal overnutrition and child undernutrition in cities and these demographics.
Evidence suggests inflammation may be a key mechanism by which psychosocial stress, including loneliness, predisposes to depression. Observational and clinical studies have suggested simvastatin, with its anti-inflammatory properties, may have a potential use in the treatment of depression. Previous experimental medicine trials investigating 7-day use of statins showed conflicting results, with simvastatin displaying a more positive effect on emotional processing compared with atorvastatin. It is possible that statins require longer administration in predisposed individuals before showing the expected positive effects on emotional processing.
Aims
Here, we aim to test the neuropsychological effects of 28-day simvastatin administration versus placebo, in healthy volunteers at risk for depression owing to loneliness.
Method
This is a remote experimental medicine study. One hundred participants across the UK will be recruited and randomised to either 28-day 20 mg simvastatin or placebo in a double-blind fashion. Before and after administration, participants will complete an online testing session involving tasks of emotional processing and reward learning, processes related to vulnerability to depression. Working memory will also be assessed and waking salivary cortisol samples will be collected. The primary outcome will be accuracy in identifying emotions in a facial expression recognition task, comparing the two groups across time.
The coronavirus disease 2019 (COVID-19) pandemic and the resulting containment measures, such as “lockdown” and “social distancing”, have had important consequences on people’s mental and physical health.
Objectives
We aimed to study the effect of social isolation and subsequent re- exposure and eventual changes in general and ED-specific psychopathology in people with Eating Disorders (EDs).
Methods
Three-hundred twelve Italian people with EDs (179 Anorexia Nervosa, 83 Bulimia Nervosa, 48 Binge Eating Disorder and 22 Other Specific Feeding Eating Disorder) were asked to fill-in an online survey to explore several dimensions such as: anxiety, depression, panic, insomnia, suicide ideation, stress, post-traumatic stress and obsessive-compulsive symptoms. Differences in ED specific and general symptoms among the 3 investigated time periods (before, during and after the end of lockdown) were assessed with a one-way ANOVA with repeated measures. Subsequently, ED diagnosis was introduced as covariate in the analysis in order to investigate the possible contribution on psychopathological changes.
Results
ED core symptoms increased during the lockdown but most of them returned to pre-COVID19 levels at re-opening. The severity of general psychopathology also increased during the lockdown and persisted high in the following phase, except for depression and suicide ideation. None of this symptoms was affected by ED diagnosis, participants’age and illness duration.
Conclusions
People with EDs showed worsening of both general and specific psychopathology; moreover, changes in general psychopathology persisted in the re-opening period suggesting a higher stress vulnerability in this kind of patients.
The problem of occupational stress in healthcare workers is hardly new, but effective interventions in this area are lacking despite being sorely needed – especially in the ongoing COVID-19 pandemic. The results of a Cochrane review suggest that cognitive–behavioural therapy and mental and physical relaxation reduce stress more than no intervention but not more than alternative interventions, and that changing work schedules may lead to a reduction of stress. Other organisational interventions showed no effect on stress levels. However, the evidence is of low quality owing to risk of bias and lack of precision. This commentary critically appraises the review and attempts to put its findings into the current real-world context.
Since Plio-Pleistocene time, southward migration of shortening in the eastern part of the Greater Caucasus into the Kura foreland basin has progressively formed the Kura fold–thrust belt and Alazani piggyback basin, which separates the Kura fold–thrust belt from the Greater Caucasus. Previous work argued for an eastward propagation of the Kura fold–thrust belt, but this hypothesis was based on coarse geological maps and speculative ages for units within the Kura fold–thrust belt. Here we investigate the initiation of deformation within the Gombori range in the western Kura fold–thrust belt and evaluate this eastward propagation hypothesis. Sediments exposed in the Gombori range have a Greater Caucasus source, despite the modern drainage network in the NE Gombori range, which is dominated by NE-flowing rivers. Palaeocurrent analyses of the oldest and youngest syntectonic units indicate a switch happened between ~2.7 Ma and 1 Ma from dominantly SW-directed flow to palaeocurrents more similar to the modern drainage network. A single successful 26Al–10Be burial date indicates the youngest syntectonic sediments are 1.0 ± 1.0 Ma, which, while not a precise age, is consistent with original mapping suggesting these sediments are of Akchagylian–Apsheronian (2.7–0.88 Ma) age. These results, along with recent updated dating of thrust initiation in the eastern Kura fold–thrust belt, suggest that deformation within the Kura fold–thrust belt initiated synchronously or nearly synchronously along-strike. We additionally use topographic analyses to show that the Gombori range continues to be a zone of active deformation.
Literature underlines that the Edinburgh Postnatal Depression Scale (EPDS) was the most common measure to assess pregnancy and postpartum depression worldwide and suggests that the rate of false positive cases is high. Furthermore, the EPDS measures, but not distinguish between depression and anxiety. The aim of this study was to value the ability of the Mood Spectrum Self Report Last Month (MOOD SR LM) to detect the rate of false positive obtained with EPDS
Method
We recruited 81 pregnant women at the third month of pregnancy. 32 women were affected by Major Depression (MD) assessed by Structured Clinical Interview for DSM IV Axis I Diagnosis and 49 women had EPDS score ≥ 13 but didn’t reach the diagnosis of MD by SCID I(False posivite group). Women were administered with the Postpartum Depression Predictors Inventory-Revised (PDPI-R), MOOD SR-LM, Work and Social Adjustment Scale(WSAS) at the third month of pregnancy.
Results
The two groups wasn't different concerning the average scores using PDPI and EPDS. The WSAS average scores were higher in the depressed women group than in the false positive group. Tree factors of MOOD SR LR (“Depressive Mood”, “Psychomotor Retardation and “Drug/Illness related Depression”) had higher average scores in the depressed women group than in the false positive group.
Conclusion
To our results, MOOD SR LM seem to be able to decrease the false positive cases. Further studies concerning this use of MOOD SR LM are necessary.
Perinatal depression is a particolar challenge to clinicians, and its prevalence estimates are difficult to compare across studies. Furthermore,there are no studies that systematically assessed the incidence of perinatal depression. The aim of this study is to estimate prevalence, incidence, recurrence and new onset of DSM IV minor and major depression (mMD) in an unselected population of pregnant women.
Method
1066 pregnant women were recruited at third month of pregnancy (T0), and minor/major depression (mMD) was assessed by the Structured Clinical Interview for DSM IV disorders (SCID I). The SCID I was administered at baseline evaluation (T0), the Edimburgh Postnatal Depression Scale (EPDS) was administered at third, 6th (T1), 8th (T2) month of pregnancy, and the SCID I Mood module was administered to confirme an eventual DSM-IV minor or major depression diagnosis when the EPDS score was≥13.
Results
The pregnancy period prevalence of mMD was 12,4%.The point prevalence of mMD decreased from 8,6% at the 3rd month of pregnancy to 1,7% at the 8th month of pregnancy.The cumulative incidence of mMD was 2,2%. The weighted incidence of new onsets during pregnancy was 1,6%. The weighted percentage of recurrences during pregnancy was 3,7%.
Conclusion
The decline in the point prevalence during the second and third trimester of pregnancy found in our study may be attributed to psychological counselling and/or pharmacological treatment.Further studies about new onsets of depression during pregnancy are highly important in order to improve clinical prediction of risk in any individual woman.
Depression during pregnancy is associated to physical symptoms that can impair the functioning of women; furthermore some of the depression somatic symptoms (i.e., sleep disturbance, fatigue, weight change and appetite) are also features of pregnancy. The overlap of symptomatology can interfere with the identification and the diagnosis of the mood episode. Aim of this study is to compare the the depressive phenomenology and the presence of Axis I comorbidity between pregnant and non pregnant depressed women.
Method
We diagnosed Major Depression (MD) using the Structured Clinical Interview for Axis I Diagnosis DSM IV (SCID I) in 32 pregnant women at third month of pregnancy and 87 non pregnant women and we compared the depressive phenomenology in the two groups. Then we administered the Mood Spectrum Self Repost Last Month (MOOD SR-LM) in the two group in order to study the mood spectrum symptomatology.
Results
Pregnant depressed women have higher psychomotor retardation, higher levels of concentration and lower agitation than non pregnant depressed women.
The severity of depression symptoms was similar in the two depressed groups.
Conclusion
Our results agree with current litterature about the presence of psychomotor retardation in depressed pregnant women.
The higher level of concentration in pregnant women could be explained by the high comorbidity with Generalized Anxiety Disorder (GAD). In the pregnant depressed women the Obsessive-Compulsive Disorder (OCD) and Panic Disorder (PD) comorbidity are more rappresentated.
Global warming and the associated glacier retreat recently revealed the entrance to an ice–rock tunnel, at an altitude of ~3600 m a.s.l., in the uppermost portion of the Forni Glacier in the Central Italian Alps. The tunnel served as an entrance to an Austro-Hungarian cableway station excavated in the rocks during the Great War just behind the frontline. A comprehensive geophysical survey, based on seismic and ground-penetrating radar profiling, was then undertaken to map other possible World War I (WWI) remains still embedded in the ice. The ice–rock interface was reconstructed over the entire saddle and in the uppermost portion of the glacier. A prominent linear reflector was surprisingly similar to the common response of buried pipes. The reflector orientation, almost longitudinal to the slope, does not seem to be compatible with a glacial conduit or with other natural features. Numerical simulations of a series of possible targets constrained interpretation to a partly water-filled rounded shape cavity. The presence of a preserved WWI tunnel connecting Mount Vioz and Punta Linke could be considered a realistic hypothesis. The Forni glacier could be still considered polythermal and comprised of cold ice without basal sliding in its top portion.
Probably, the long-term monitoring of the solar atmosphere started in Italy with the first telescopic observations of the Sun made by Galileo Galilei in the early 17th century. His recorded observations and science results, as well as the work carried out by other following outstanding Italian astronomers inspired the start of institutional programs of regular solar observations at the Arcetri, Catania, and Rome Observatories.
These programs have accumulated daily images of the solar photosphere and chromosphere taken at various spectral bands over a time span larger than 80 years. In the last two decades, regular solar observations were continued with digital cameras only at the Catania and Rome Observatories, which are now part of the INAF National Institute for Astrophysics. At the two sites, daily solar images are taken at the photospheric G-band, Blue (λ = 409.4 nm), and Red (λ = 606.9 nm) continua spectral ranges and at the chromospheric Ca II K and Hα lines, with a 2″ spatial resolution.
Solar observation in Italy, which benefits from over 2500 hours of yearly sunshine, currently aims at the operational monitoring of solar activity and long-term variability and at the continuation of the historical series as well. Existing instruments will be soon enriched by the SAMM double channel telescope equipped with magneto-optical filters that will enable the tomography of the solar atmosphere with simultaneous observations at the K I 769.9 nm and Na I D 589.0 nm lines. In this contribution, we present the available observations and outline their scientific relevance.
Microtremor measurements and the horizontal-to-vertical spectral ratio (HVSR)
technique, generally used for site effect studies as well as to determine the
thickness of soft sedimentary layers, can effectively be applied to map the
thickness of glaciers. In this work the radio-echo sounding, geoelectric and
active seismic methods, widely employed to image the earth interior, are applied
to verify the reliability of the HVSR technique in Alpine and Antarctic glacial
environments. The technique has been used to analyze passive seismic data from
glaciers of the Adamello and Ortles-Cevedale massifs (Italy), the Bernese
Oberland Alps (Switzerland) and from the Whillans Ice Stream (West Antarctica).
Comparing with the results obtained from the different geophysical imaging
methods, we show that the resonance frequency in the HVSR spectra correlates
well with the ice thickness at the site, in a wide range from a few tens of
meters to more than 800 m. The reliability of the method mainly depends
on the coupling of sensors at the glacier surface and on the basal impedance
contrast. This passive seismic technique offers a logistically efficient and
cost effective method to map glacier and ice-sheet thicknesses. Moreover, under
certain conditions, it allows reliable estimations of the basal seismic
properties.
The objective of this study was to estimate the genetic parameters for thermoregulation traits and the relationships with performance of Large White lactating sows reared in a tropical humid climate. The thermoregulation traits were rectal temperature (RT), cutaneous temperature (CT) and respiratory rate (RR) during lactation measured in the afternoon (1200 h) and in the morning (0700 h). The production traits were sow’s average daily feed intake (ADFI), litter BW gain (LBWg) and sow’s proportion of BW change between farrowing and weaning (BWc). Complete data included 931 lactating performance on 329 Large White sows from the INRA experimental unit in Guadeloupe (French West Indies). Random regression models using linear spline functions were used for longitudinal data (RT, CT, RR and daily feed intake). Results showed that when ignoring values at the beginning and the end of lactation, the traits studied can be treated as the same trait throughout days of lactation, with fairly constant heritability and variance. However, largest heritabilities and genetic variances were estimated in mid-lactation. Heritability estimates on average performance during lactation were low to moderate for thermoregulation traits (0.35±0.09 for RT, 0.34±0.12 for CT and 0.39±0.13 for RR). Heritability estimates for production traits were 0.26±0.08 for ADFI, 0.20±0.07 for BWc and 0.31±0.09 for LBWg. Significant genetic correlations between thermoregulation traits and production traits were only obtained for ADFI and RR (0.35±0.12). From this study it can be concluded that thermoregulation traits are heritable, indicating that there are genetic differences in heat stress tolerance in lactating Large White sows.
In this paper an associative-parametric approach is proposed in order to model the mesh of an aeronautical concept starting from a set of high-level structural primitives. This approach allows the designer to carry out the geometric modelling and the automatic mesh generation within one software environment in a fast and interactive way. The structural optimisation process is then simplified, with a relevant man-hours saving. A lower number of data transfers between different software is, moreover, involved with less problems related to the data corruption. To assure orders of continuity higher than C0 between adjacent instances, a suitable mathematical description of the structural primitives has been proposed. This description assures the maintenance of the required continuity constraints when the mesh is modified. Appropriate schemes of dependences are identified to guarantee the automatic propagation of the modifications complying with the continuity constraints.
The main objective of the present work was to determine the nutritional value and the strategies of using green banana meal (BM) in growing pigs. Two trials involving a total of 96 growing pigs were designed to study the effect of the harvest stage on the nutritional and energy values of BM (trial 1) and to evaluate the consequence of feeding gradual levels of BM on growth performance and feeding behavior in growing pigs (trial 2). In trial 1, the digestive utilization of three diets including 40% BM were compared with a control (C) soybean meal-corn diet in two batches of 12 pigs. BM was obtained from fruits harvested at 750 degrees-days (DD; early harvesting stage), 900 DD (normal harvesting stage) and 1150 DD (late harvesting stage). In trial 2, 72 Large White pigs were grouped in pens of nine animals and were given ad libitum access to one of the four dietary treatments (two pens/diet) differing from the rate of inclusion of 900 DD BM (0%, 20%, 40%, 60%). The estimated energy apparent digestibility coefficients of BM increased with the harvest stage (75.5%, 80.7% and 83.2% for BM at 750, 900 and 1150 DD, respectively). Digestible energy and metabolizable energy values were higher for BM at 1150 DD (13.56 and 13.05 MJ/kg DM, respectively) than at 900 DD (13.11 and 12.75 MJ/kg DM, respectively) or at 750 DD (12.00 and 11.75 MJ/kg DM, respectively). In trial 2, average daily gain and feed conversion ratio were not affected (P>0.05) by the rate of BM inclusion (822 g/day and 2.75 kg/kg on average, respectively). Feed intake and feeding behavior parameters were not significantly influenced by the dietary treatments except for the rate of feed ingestion with a lower value for the diet with 40% of BM (27.4 v. 32.2 g/min on average; P<0.01) when compared with the other diets. Results of this study indicate that the energy value of BM increases with the harvest stage and that BM can be incorporated up to 60% in growing finishing pig diets.
The nature of the intermetallic layer which forms on the steel surface during immersionin typical galvanizing baths for galvannealed (GA) sheets production has been investigatedon two commercial Titanium-stabilized Interstitial-Free (Ti-IF) steel substratesgalvanized in baths with different Al contents. Results from this study show that in bothcases the inhibition layer is biphasic and composed of a very thin Al-rich phase layer,identified as Fe2Al5Znx, and a thicker Zn-rich phase layeron top of it, identified as δ. Experimental results also show that theFe2Al5Znx phase layer becomes discontinuouswhen decreasing the bath Al content. Discussions about the mechanisms of formation and thefinal microstructure of this inhibiting layer are also tackled in this paper by means ofthe Al-Fe-Zn ternary phase diagram at 460 °C and assumptions to justify any deviation fromthermodynamic equilibrium are as well proposed.
Movies of magnetograms of sunspots often show small-size magnetic patches that move radially away and seem to be expelled from the field of the spot. These patches are named Moving Magnetic Features (MMFs). They have been mostly observed around spots and have been interpreted as manifestations of penumbral filaments. Nevertheless, few observations of MMFS streaming out from spots without penumbra have been reported. He we investigate the physical properties of MMFs observed around the field of a pore derived by the analyses of high spectral, spatial and temporal resolution data acquired at the Dunn Solar Telescope with IBIS. We find that the main properties of the investigated features agree with those reported for MMFs observed around regular spots. These results indicate that an improvement of current numerical simulations is required to understand the generation of MMFs in the lack of penumbrae.
The seasonal variation of adult populations of Haematobia irritans Linnaeus was monitored at Santa Fe, Argentina from August 1992 to August 1994 by weekly counts of flies on grazing heifers. Each year, flies were recorded at a density of more than two flies per heifer from August/September to the following June, with peaks of abundance in mid to late spring and late summer to mid autumn. The seasonal trend of fly numbers was best correlated with the mean temperature 4 weeks prior to each fly count (correlation indices of P<0.01 in six of the nine fly periods) followed by the previous 4 week mean saturation deficit. Rainfall and relative humidity correlated poorly with the seasonality of H. irritans. Temperature appeared crucial at the beginning (late winter) and at the end (early-mid autumn) of the fly season while its relevance diminished in the middle of the season. The percentage of heifers that were infested decreased from 80–100% in the fly season to 0–55% between fly seasons but H. irritans never disappeared from the heards, indicating that if diapause occurs at the latitude of the study area, part of the fly population was not sensitive to diapause inducing factors.
We present here the first large-scale genetic characterization of grape cultivars from Transcaucasia and Anatolia. These regions where wild grapes still grow in nature have been cultivating wine and table grapes for thousands of years and are considered the cradles of viticulture. Using 12 nuclear microsatellite markers, we genotyped 116 accessions of traditional grape cultivars from Armenia, Georgia and Turkey and we detected 17 identical genotypes and six homonymy cases, mainly within each national germplasm. Neighbour-joining analysis of genetic distance showed that each germplasm could have multiple origins and although they are now separated, they might have some common ancestors. In addition, four varieties from Western Europe included as outgroups turned out to be more related to Georgian cultivars than other germplasms, suggesting a possible ancient origin in Georgia. This work represents a first step towards germplasm management of this rich ampelographic heritage.
In continuous hot dip galvanizing, steel strip is immersed in a molten zinc bath
containing small amounts of aluminium. A model has been developed describing the kinetics
of the galvanizing reactions that occur at the steel/liquid zinc interface (dissolution
of iron, heterogeneous nucleation and growth of the intermetallic phase
Fe2Al5Znx). The model has been validated using experimental
data available in the literature for a three-second galvanizing treatment.
We investigate the optical properties of InGaAs QDs emitting at 1330 nm, directly grown by Metal Organic Chemical Vapor Deposition (MOCVD) in a GaAs matrix, without indium in the barrier. The PL characterization of this new kind of QDs, shows very narrow lineshape at room temperature and a strong reduction of the temperature dependent quenching of the emission (a factor of 3 from 30 K to 300 K).
The quantum external efficiency obtained by inserting such QDs into light emitting diode structures, despite the low dot density (1.6*109 cm−2), is 0.03%. This value corresponds to an individual QD efficiency about 30% higher than that reported in the literature for state of art InGaAs/InGaAs QD LEDs.